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Dartmouth Brain Imaging Laboratory

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									NA-MIC
National Alliance for Medical Image Computing
http://na-mic.org




Dartmouth Brain Imaging
      Laboratory
 Site PI: Andrew J. Saykin, Psy.D.
NA-MIC
National Alliance for Medical Image Computing
http://na-mic.org




                                ( http://synapse.hitchcock.org/ )
            Brain Imaging Laboratory
- The Dartmouth BIL was established in 1993 as an
   fMRI and brain morphometry research program.
- It is a collaborative, multidisciplinary program
   including faculty from Psychiatry, Radiology,
   Neurology, Neurosurgery, Neuropathology,
   Molecular Genetics, Computer Science & beyond.
- Four programmatic goals:
        (1) Clinical Neuroscience Research
        (2) Advanced Education and Training
        (3) Technical Development
        (4) Study Normal Human Brain Function

   National Alliance for Medical Image Computing
   http://na-mic.org
             December 2005:
  Neuroimaging Research Center 3T Magnet




National Alliance for Medical Image Computing
http://na-mic.org
    Brain Imaging Laboratory: People
FACULTY PIs (Psychiatry):                           BIL COORDINATOR
•  Laura A. Flashman, Ph.D.                         •   Heather Pixley, B.A.
•  Alan I. Green, M.D.
•  Thomas W. McAllister, M.D.                       IMAGE ANALYSTS & SYSTEMS ADMIN:
•  Brenna C. McDonald, Psy.D.                       •  John MacDonald, M.A.
•  Robert M. Roth, Ph.D.                            •  Tara McHugh, M.A.
•  Andrew J. Saykin, Psy.D.                         •  Paul Wang, B.A.
•  Heather A. Wishart, Ph.D.                        •  John West, M.S.

POST-DOCTORAL FELLOWS:                              STUDY COORDINATORS:
•  Howard Cleavinger, Ph.D. (Epilepsy)              •  Mary Hynes, RN (TBI)
•  Ellen Crouse, Ph.D. (MCI, chemotherapy)          •  Ariel Rosen, B.A. (MS)
•  Nancy Koven, Ph.D. (Schizophrenia)
•  Nadia Paré Ph.D. (MCI, ADNI)                     NEUROSCIENCE TECHNICIANS:
•  Jo Cara Pendergrass, Ph.D. (Schizophrenia)       •  Carrie Kruck, B.A. (chemotherapy)
                                                    •  Margaret Nordstrom, B.A. (MCI)
KEY TECHNICAL COLLABORATORS:
•  Konstantinos Arfanakis, Ph.D. (DTI; IIT)         RESEARCH MRI TECHNOLOGISTS:
•  Fillia Makedon , Ph.D. (Computer Science)        •  Jorge A. Forero
•  James C. Ford, Ph.D. (Computer Science)          •  Alice E. Davison
•  Li Shen, Ph.D. (CS, UMASS-Dartmouth)
•  Jason Moore, Ph.D. (Comp Genetics)

    National Alliance for Medical Image Computing
    http://na-mic.org
           Key Contributors to NA-MIC
Schizophrenia Recruitment/Assessment & fMRI Subproject PIs:
•   Laura A. Flashman, Ph.D., Associate Professor (Awareness & Memory)
•   Robert M. Roth, Ph.D., Assistant Professor (Reward fMRI, Morphometry)
•   Alan I. Green, M.D., Professor & Chair (Dual Dx and Reward fMRI)
•   Thomas W. McAllister, M.D., Professor (Awareness & Memory)
•   Andrew J. Saykin, Psy.D., Professor & Site PI (Memory Systems)
Post-doc Fellows: Nancy Koven, Ph.D & Jo Cara Pendergrass, Ph.D.
Research Staff:
• John West, M.S., Image Analysis and Scripting for fMRI, VBM, & DTI
• Heather Pixley, B.A., Coordination, IRB Issues, Image Analysis
• John MacDonald, M.A., Systems Administration, QC, Data Security
• Tara McHugh, M.A., Brain Morphometry Analysis
• Paul Wang, B.A., Brain Morphometry, Callosum project, Database

         National Alliance for Medical Image Computing
         http://na-mic.org
              Contributors to NA-MIC:
             Related Neuroimaging Work
• Robert M. Roth, Ph.D., Assistant Professor
   – Bipolar disorder and OCD (NARSAD, ADAA, Hitchcock Foundation, NCD)
• Thomas W. McAllister, M.D., Professor
   – fMRI Pharmacology and genetics of traumatic brain injury (NINDS, NICHD)
• Andrew J. Saykin, Psy.D., Professor (Site PI)
   – Preclinical Alzheimer’s disease and MCI (fMRI, DTI, morphometry) (NIA)
   – Imaging of cognitive effects of cancer chemotherapy (NCI)
   – Pending imaging projects on neurogenetics & cytokine biomarkers
• Brenna C. McDonald, Psy.D., Assistant Professor
   – Pediatric neuroimaging in epilepsy & TBI, clinical presurgical fMRI (EF)
• Heather A. Wishart, Ph.D., Assistant Professor
   – fMRI and lesion analysis in multiple sclerosis (NMSS, NINDS K23)
• Ann Christine Duhaime, M.D. Professor (Neurosurgery)
   – fMRI study of pediatric brain injury using a piglet model (NICHD)
        National Alliance for Medical Image Computing
        http://na-mic.org
       How NAMIC Fits into Portfolio
• Every project in the BIL requires advanced image analysis tools – this
  makes NAMIC a high priority.
• Most projects combine fMRI, manual and voxel-based morphometry
  and DTI – data integration is a special priority.
• The BIL team contributes expertise with fMRI methodology.
• BIL researchers contribute “driving” ideas for needed tools and features,
  test prototypes in the “real world” setting, provide feedback and plan to
  employ resulting tools in multiple scientific projects cutting across
  diseases and brain systems.
• The BIL works closely with the Core 3.1 Harvard Site and the SPL to
  achieve these goals.
• The BIL team also collaborates with Cores 1 and 2 including 2 MIT labs,
  UNC, the SPL, as well as the Training and Dissemination Cores. We
  also look forward to collaborations with other NAMIC components.


       National Alliance for Medical Image Computing
       http://na-mic.org
     Brain Imaging Lab: Sponsored Research
                               (Current and Previous)
•   Alzheimer’s Association*
•   Anxiety Disorders Association of America
•   Epilepsy Foundation*
•   Hitchcock Foundation*
•   Ira DeCamp Foundation*
•   McDonnell-Pew Foundation
•   National Alliance for Research on Schizophrenia & Depression*
•   National Inst. of Disability & Rehabilitation Research (NIDRR)*
•   National Institutes of Health*
      – NCI, NCRR, NIA, NIBIB, NICHD, NIDA, NIMH, NINDS
•   National Multiple Sclerosis Society*
•   National Science Foundation*
•   Neuroscience Research & Education Foundation
•   New Hampshire Hospital
•   Obsessive Compulsive Foundation
•   Partnership for Pediatric Epilepsy Research
•   Stanley Research Foundation
•   Industry: Pfizer & Novartis                             * multiple grants

    National Alliance for Medical Image Computing
    http://na-mic.org
        Dartmouth Brain Imaging Laboratory




                           December, 2005




National Alliance for Medical Image Computing
http://na-mic.org
Dartmouth Brain Imaging Laboratory & Alumni




National Alliance for Medical Image Computing
http://na-mic.org

								
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