Epidemiology of amebiasis Dr. Nicolas Padilla Professor of Pediatrics and Researcher Nursing and Obstetrics School of Celaya University of Guanajuato Introduction • Amebiasis is a worlding disease. • Principal frequency in countries with a deficiency in sanitary conditions. • It is more frequent in tropical countries. • Poorest areas. Frequency Region Infection Diasease Deaths Africa 85 millions 10 millions 10-30 thousands Asia 300 millions 20-30 25-50 millions thousands Europe 20 millions 100 Minimum thousands America 95 millions 10 millions 10-30 thousands Totals 650 millions 45-50 40-110 millions thousands Frequency • 10-20% of the world population. • Colombia and Brazil 40%. • Arabia 30%. • Mexico 27%. Mortality in Mexico • 1980 23% • 1998 < 1% Entamoeba histolytica • It was described more than 100 years ago. • It has two forms: infectant (cyst) or vegetative (trophozoite). Transmission • Faeces- mounth • Contaminated water • Contaminated meals • Street vendors of meals Factors for the development of amebiasis For the ameba • Phatogenicity of ameba, its virulence. • Amebas pathogenic and non-pathogenic Factors for the development of amebiasis For the host • Nutritional status • Age • Sex • Immunologic condition Factors for the development of amebiasis For the environment • Management of water • Management of waste • Habits nutritionals and hygienics Chemoprophylaxis • It is the method for to make prevention by chemical substance. • It is used in Mexico, with albendazole, to control the diseases by plathelmyntes and nemathelmyntes. Chemoprophylaxis • Quinfamide Studies on chemoprophylaxis • In Mexico, administration of quinfamide each 3 months during one year, in children, had 12.5% of frequency of amebiasis. Conclusions • The chemoprophylaxis scheme is a line of control of amebiasis, but also, we should increase the personel hygienic habits, to avoid eat in the streets and, to avoid the fecalism.