Docstoc

GINKGO BILOBA EXTRACT EPG EP Ginkgo Extract

Document Sample
GINKGO BILOBA EXTRACT EPG EP  Ginkgo Extract Powered By Docstoc
					TECHNICAL DOCUMENTATION                                                                                                   Revision: 27.04.2009


GINKGO BILOBA EXTRACT EPG 246 (EP 6.1)
NAME OF THE PLANT:                    Ginkgo biloba
PART OF THE PLANT USED:               Leaves
RATIO OF PLANT : EXTRACT:             Between 28 and 50:1
DRUG MASTER FILE (DMF):               Available in EU CTD Format
CHEMICAL DEFINITION:                  Mixture of Ginkgoflavonglycosides, Ginkgoterpenelactones and Proanthocyanidins
SYNONYMS:                             --
STRUCTURAL FORMULA:




                                                                                         CAS N. 90045-36-6
TECHNICAL DESCRIPTION:                                                      ASSAY:       - Flavonglycosides : Not less than 24.0 %
                                                                                         - Terpenelactones : Not less than 6.0 %
APPEARANCE:             Brown hygroscopic powder with                                      ginkgolides A+B+C: Between 2.8 % and 3.4 %
                        characteristic odour                                               bilobalide:        Between 2.6 % and 3.2 %
                                                                                         - Proanthocyanidins: Not more than 9.5 %
SOLUBILITY:             Soluble in ethanol/water

IDENTIFICATION:         HPLC gradient                                       IMPURITIES:
                        TLC
                                                                            GINKGOLIC ACIDS:          Less than 5 ppm
WATER CONTENT
( K. Fischer ) :        Less than 3.0 %                                     SOLVENTS:
HEAVY METALS:           Less than 10 ppm                                    ETHANOL:                  Not more than 0.5 %
                                                                            OTHERS:                   Not more than 0.1 %
SULPHATED ASH:          Less than 1.5 %

                                                                            MICROBIOLOGY:             Complies with EP

                                                                            STORAGE: Sealed container and protected from moisture



PRODUCT APPLICATIONS: Ginkgo biloba extract has an effect on the regulation of blood flow to the brain and is used primarily for the
symptomatic treatment of dementia syndrome, deficient memory, disturbances of concentration, dizziness and tinnitus. Ginkgo biloba extract is
also a free radical scavenger and powerful antioxidant.

COSMETIC APPLICATIONS: include anti ageing, free radical scavenger, antioxidant, improvement of dermal microcirculation and
stimulation of lymph drainage.

THERAPEUTIC CATEGORIES: Vasodilator, anti-ischemic, free radical scavenger and antioxidant.



Linnea SA                                      Linnea Inc. USA
Via Cantonale                                  435 McCartney Street
6595 Riazzino (Locarno)                        Easton, PA 18042
Switzerland                                    telephone: 888-253-0044 or
telephone: +41 91 850 5050                     610-253-7950
fax: +41 91 850 5070                           fax: 610-253-7970                                          www.linnea-worldwide.com

				
DOCUMENT INFO
Shared By:
Categories:
Stats:
views:105
posted:7/18/2010
language:English
pages:1
Description: GINKGO BILOBA EXTRACT EPG EP Ginkgo Extract