Docstoc

file p Sodium-PCA

Document Sample
file p  Sodium-PCA Powered By Docstoc
					   BioSpectrum, Inc.
  Specialty cosmetic actives from GREEN nature
World leading GREEN manufacturing and technology
    Heartfelt GREEN satisfaction to customers
BIOSPECTRUM




    CONTENTS
     01 We offer GREEN ingredients.
          We offer SAFE ingredients.

     02 About BioSpectrum, Inc.
          Safety and Quality Control
          Research Areas

     03 Development Process
     04 Manufacturing Process
     05 Technologies
     06 Product Range
            BOTANICALs:HerbEx & SingleEx
            Mixture of BOTANICALs:MultiEx
            Liposomes:NLT NanoSpheres and FMLT MultiSpheres
            NLT NanoSpheres
            FMLT MultiSpheres

     08 Specialty NATURAL Ingredients
            Cell Regeneration: Stem Cell Technology
     09     Anti-Aging/Anti-Wrinkle
     11     Whitening
     12     Phytoestrogens: NATURAL Hormones for Women
     13     Anti-Inflammation/Anti-Oxidant/Soothing
     15     Dermatitis Improvement/Anti-Allergy
     16     Skin Immune System Regulation
     17     Biologically Active Peptides
     18     NATURAL Humectants
     19     Anti-Microbial Activity
     20     Chemoprevention
            Hair and Scalp Care
     22   Global Network
                                                                           BIOSPECTRUM



We offer GREEN ingredients.
Every ingredient BioSpectrum is offering is GREEN-based. You will meet only with the products from
the freshest and finest herbs with verification of conformity and origin by experienced botanists from
Korea and Europe.

Jeju Island is the largest island in Korea with incomparably beautiful NATURE. Jeju Island is known
to have the richest repository of NATURAL resources. We have launched Jeju series, which is
formulated with ingredients from PLANTS grown in Jeju Island, which makes our NATURAL
ingredients very special and unique.




We offer SAFE ingredients.
Most of the ingredients BioSpectrum has developed are clinically tested for the safety and efficacy.
Besides the remarkable skin caring effects, the clinical tests have demonstrated that our ingredients
are safe to use. Our ingredients satisfy the consumer s demands with real safety and more-than
expected effects.
BIOSPECTRUM



   About BioSpectrum, Inc.
                                                                                                                      a
                                                                                                                  Kore
                                                                                                          p. of
                                                                                                     d, Re
                                                                                               Islan
                                                                                        Jeju
                                                                                ch in
                                                                       ju   Bran
                                                              um ’s Je
                                                         pectr
                                                     BioS




   BioSpectrum is a leading developer and supplier of innovative specialty cosmetic ingredients. With
   profound knowledge and experience on PLANTs, formulation, and biological science, BioSpectrum is
   able to design and develop high-quality active ingredients for cosmetics. Our R&D team has put
   ceaseless efforts to search NATURE-derived candidates for skin care ingredients, which can be
   suggested as the alternatives for the currently using chemical cosmetic actives. BioSpectrum has
   optimized the concentration and formulation of each active ingredient based on professional knowledge
   and active research on skin disease, transdermal delivery system, skin cell-based screening system,
   and various liposome formulations.


   Safety and Quality Control
   BioSpectrum pursues high ideals to care our NATURE. We strive to make our manufacturing
   processes to be eco-compatible. We offer ECO-FRIENDLY products by using NATURE as the
   source. We’ve set up company safety and quality standards, and we endeavor to respect the
   regulatory guidelines to regulate our manufacturing process and, consequently, to control the quality
   of our products


   Research Areas
   Besides taking active researches on skin diseases, transdermal delivery system, skin cell-based
   screening system, and various liposome formulations, we have been endeavored to develop new
   technologies through the integration of stem cell technologies with cosmetics. As the result, we°Øve
   secured our unique stem cell-cosmetic technologies, and we have successfully developed our brand
   new line for stem cell-based ingredients.




                                                                                                                          BioSpectrum’s R&D Team


   02-   BioSpectrum
                                             BIOSPECTRUM



Development Process
>> Applied Techniques for NATURAL Products




                                                BioSpectrum -03
BIOSPECTRUM



   Manufacturing Process
   BioSpectrum employs its own unique technologies, as well as very well-known traditional technologies,
   to transform the NATURE into outstanding ingredients for personal care products. Every manufacturing
   process is carried out using advanced facilities including our Jeju branch. Jeju Island is the largest
   island in Korea with incomparably beautiful NATURE. Jeju Island is known to have the richest
   repository of NATURAL resources in Korea. AII of our ingredients developed in BioSpectrum are from
   plants grown in Jeju Island, except for the ones that are not native in Jeju Island. This is why our
   NATURAL ingredients are special and unique.

   BioSpectrum pursues to care our NATURE. We strive to make our manufacturing processes to be eco
   compatible. The quality of our products is controlled by following the safety and quality standards set up
   in our company and by respecting the regulatory guidelines in our every manufacturing process.




   04-   BioSpectrum
                                                                                BIOSPECTRUM



Technologies
BioSpectrum has developed its own unique technologies to convert NATURE-based raw materials into
active ingredients and technologies to deliver most efficiently to skins. By providing products with state
of the art technologies, which meet the high standards demanded by the personal care markets, we
can proudly say that our customers and their consumers are pleased with our products.

HerbEx technology is our advanced purification and concentration technology to produce PLANT
extract with high levels of purity. SingleEx technology is developed to offer highly active substances
from PLANT extracts. MultiEx technology is strategically utilized to formulate the mixture of active
ingredients. Technologies named NLT and FMLT, which are mono-layered and multi-layered
liposomes, respectively, are to embrace delicate and/or lipophilic ingredients with liposomes, and hence
to let the ingredients to exert their highest activity.



   TECHNOLOGY                PRODUCT                               BRIEF DESCRIPTION



                                                    Vegetable extracts obtained from over 50 kinds of
HerbEx technology          HerbEx Series
                                                    fresh plants




                                                    Highly purified active ingredients
SingleEx technology       SingleEx Series
                                                    (Over 10 items)




                                                    Formulation of mixture of active ingredients
MultiEx technology         MultiEx Series
                                                    (Over 5 items)



                                                    Nano Lipo Technology
         NLT                NanoSpheres             Nano-sized mono-layered liposomes
                                                    (Over 10 items)


                                                    Fast Multi-layered Liposome Technology
        FMLT                MultiSpheres            Multi-layered liposome preparation method;
                                                    PCT patent pending




                                                                                              BioSpectrum -05
BIOSPECTRUM



   Product Range
   >> BOTANICALs: HerbEx & SingleEx
   Through the exclusive process developed by BioSpectrum, plant mass is extracted, condensed, and
   developed as HerbEx series with approximately 10-fold condensed. Further concentration and
   purification of plant extracts makes it possible to offer highly purified NATURAL raw ingredients with
   caring activities (SingleEx series). All of the tinctures or extracted dry powders are subject to strict
   quality control. Each batch is examined carefully and stored in our special storage cellars.




   >> Mixture of BOTANICALs: MultiEx
   One of the major impediments in cosmeceutical industry is that highly concentrated cosmetic
   ingredients must be used to obtain targeted biological activities. However, even though the ingredients
   are highly purified, they are not as pure enough as to be used in pharmaceuticals. These impurities in
   highly concentrated cosmetic ingredients may cause allergic responses and particular side effects.
   When the concentration of ingredients is lowered to reduce the unwanted detrimental effects, it surely
   decreases the unwanted effects, however, the targeted beneficial actions on skin are merely
   demonstrated.

   Traditional Korean Medicine, different from occidental medicine, has been developed as oriental
   blending of numerous ingredients, which have shown similar or complementary effects for centuries.
   The rationale of BioSpectrum’s MultiEx Series is developed based on the Traditional Korean Medicine.
   It has been proved to have stronger activity than single compounds but with little side effects.

   Every product of MultiEx Series has been passed through several physiological tests to prove its
   activities on the action sites MultiEx Series are put through the clinical tests to evaluate the irritation
   effects and efficacy on human skin.


   >> Liposomes: NLT NanoSpheres and FMLT MultiSpheres
   In liposomes, which are capable in embracing both water-soluble and water-insoluble materials in a
   formulation at the same time, proteins, peptides, and other active ingredients can be contained together
   in one formulation. Besides, since the membrane of liposome is composed of lipid bilayers, which is
   very similar to skin, liposome is very compatible with skin and penetrates skin layers easily.

   BioSpectrum’s innovative and unique delivery technology provides effectively acting local therapies
   through topical application of nano-size liposome. This delivery platform allows more effective and
   superior local delivery compared to other traditional cosmetic delivery methods, by delivering greater
   quantity of active ingredients to the action site with reduced systemic side effects.




   06-   BioSpectrum
                                                                               BIOSPECTRUM



Product Range
>> NLT NanoSpheres
  Easily penetrate and soak into the skin
  Able to directly deliver biologically active substances into deep skin
  Deliver moisturizing substances directly into the skin
  Able to soothe the dermal irritative actions of several known cosmetic components (eg. retinol)
  Biodegradable and non-toxic
  Carry both water and oil soluble payloads


The NLT (Nano Lipo Technology) NanoSphere series utilizes the special characteristics of liposome:
delivering greater quantity of active ingredients to the action site with the reduction in systemic side
effects. NLT NanoSphere series exerts excellent and long lasting moisturizing and biochemical effects.
NLT NanoSphere series makes it possible to produce functional skin care products with superb effects
and comforts in use.




>> FMLT MultiSpheres
  High and sustained moisturizing profiles
  Higher diffusion profile on the horny layer
  Higher stability than general liposomes

Formulation technology for preparation of liposomes with large numbers of bilayers enables the
liposomes to encapsulate corpious amounts of both hydrophobic and hydrophilic ingredients. This
maximizes the payload of liposome and leverages its spontaneous association with active ingredients.

BioSpectrum’s FMLT (Fast Multi-layered Liposome Technology) MultiSphere series is formulated by
incorporation of multi-layered liposomes, which encapsulates corpious amounts of both hydrophobic
and hydrophilic ingredients in one formulation. The FMLT MultiSpheres maximize the payloads of
liposomes by spontaneous association of multiple active ingredients. The FMLT MultiSpheres are highly
efficient in entrapment and association of active ingredients. The multiple layers of membranes in the
FMLT MultiSpheres increase the capacity of each liposome to carry the ingredient by approximately
1000-fold. This makes it possible to anticipate 1000-fold of desired active effects. Especially for topical
applications, FMLT MultiSpheres are more effective since they increase the surface area of action sites
for ingredients in tissues. Hydrophobic coating of FMLT MultiSpheres enables the liposomes to
incorporate in the most of the cosmetic formulations except for the cleansers.




                                                                                            BioSpectrum -07
BIOSPECTRUM




              Cell Regeneration: Stem Cell Technology
             Stem cells are specific cells found in most of multi-cellular organisms. They possess the ability to renew
             themselves through cell division and to differentiate into a diverse range of specialized cell types. Adult
             stem cells, which are very specialized and lineage-restricted, readily differentiate into young and healthy
             dermal cells. However, as skin ages, the number of skin stem cells decreases and renewing activity of
             skin stem cells becomes less efficient leading to aged skin. Therefore, Incorporation of the stem cell
             technology in cosmetics is very promising and sensational in terms of bringing skin rejuvenation back.

             BioSpectrum’s stem cell technology is established through unflagging efforts and innovative researches,
             and finally succeeded in proposing very new passage to approach skin rejuvenation. Our newly
             developed stem cell products, originated from PLANTs, deliver vital energy to skin by nourishing the
             skin cells on all sides. They also empowers the regenerating system of skin to counteract the
             senescence signs, making skin to be enlivened, strengthened, and rejuvenated.



                                                Cell regeneration
                    Product Name                   Anti-aging/Anti-wrinkle                               INCI Name
                                                   Biologically active peptide


                                                                                 Hydrolyzed pea protein, Lecithin,
                      EMortal                                                    Olea europaea (Olive) fruit oil, Phytosterols, Squalane,
                                                                                 Ceramide 3, Butyrospermum parkii (Shea butter), Water




                                                                                 Hydrolyzed wheat protein, Lecithin,
                      EverLaSkin                                                 Olea europaea (Olive) fruit oil, Phytosterols, Squalane,
                                                                                 Ceramide 3, Butyrospermum parkii (Shea butter), Water




08-   BioSpectrum
                                                                                                BIOSPECTRUM



Anti-Aging/Anti-Wrinkle
Fine lines and wrinkles, the unwelcomed indicators of age, continue to be prime concerns for women.
Women are desperately looking for products and lifestyle advices to defy against aging signs and to bring
youthful elastic skin back.

Scientific and clinical studies say that aging processes are largely a series of disorders in metabolic
processes. To put simply, our cell structure starts to break down affecting all parts of our bodies: skin, hair,
bones, internal organs, eyesight, and etc. There are some natural plant extracts, which can suppress
these disorders by repairing old decaying cells, causing them to rejuvenate, thus actually reversing the
aging process.

Underlying theories on the development of BioSpectrum’s anti-aging products are to promote skin
epidermization, strengthen the structuration of extracellular matrix by fibroblast proliferation, and/or protect
structure proteins from degrading enzymes. The products in anti-aging category ranges from
phytoestrogens, which restores hormonal balance to photoprotectors, anti-oxidants, and DNA-repairing
agents, which make up the damages caused by external or internal factors. In vitro tests to were
performed for all of our products to test the efficacies on anti-oxidation, anti-wrinkle, whitening, and wound
healing.



                                      Anti-aging/Anti-wrinkle
         Product Name                   Whitening                                             INCI Name
                                        Phytoestrogen
                                        Natural humectant

      HerbEx Acerola                                            Malpighia glabra (Acerola) fruit extract

      HerbEx Eucomia                                            Eucommia ulmoides leaf extract

      HerbEx Flexin                                             Yeast extract

      HerbEx Horsetail                                          Equisetum giganteum extract

      Jeju LineFix (Patented)                                   Hypochoeris radicata extract

      Jeju Citrus Narinoid                                      Naringin, Water, Glycerin

      Jeju Citrus Quercetinone                                  Quercetin, Water, Glycerin

                                                                Soy isoflavenes, Cimicifuga racemosa root extract, Polygonum
                                                                cuspidatum root extract, Pueraria lobata root extract, Angelica
      MultiEx Phytrogen                                         polymorpha sinensis root extract, Punica granatum extract, Trifolium
                                                                pratense (Clover) flower extract, Pueraria mirifica root extract

                                                                Pueraria mirifica root extract, Cimicifuga racemosa root extract,
                                                                Glycyrrhiza glabra (Licorice) root extract, Punica granatum extract,
      MultiEx Hydro-Phytogenix                                  Equisetum arvense extract, Panax ginseng root extract, Camellia
                                                                sinensis leaf extract

                                                                Glycyrrhiza glabra (Licorice) root extract, Panax ginseng root extract,
      MultiEx Sapomax                                           Dioscorea villosa (Wild yam) root extract, Kigelia africana fruit extract,
                                                                Equisetum giganteum extract




                                                                                                                         BioSpectrum -09
BIOSPECTRUM




   Anti-Aging/Anti-Wrinkle
                                         Anti-aging/Anti-wrinkle
                                           Phytoestrogen
             Product Name                                                                                     INCI Name
                                           Soothing/Antioxidant/Anti-inflammation
                                           Dermatitis improvement/Anti-allergy

     Jeju Citrus Aglyconoid Sol                                                 Hesperetin, Naringenin, Quercetin, Glycerin, Water

     Jeju Citrus Glyconoid Sol                                                      Hesperidin, Naringin, Rutin, Glycerin, Water

     NLT AdenoSphere 2.0
                                                                                Adenosine, Lecithin, Butylene glycol
     (KFDA-Registered)

     NLT GinsenoSphere 2.0                                                      Panax ginseng root extract, Lecithin, Butylene glycol, Water

     NLT QueSphere 2.0                                                          Quercetin, Lecithin, Butylene glycol

     Vita-E NanoEmulsion                                                        Tocopheryl acetate, Lecithin, Glycerin, Water

                                                                                Asiaticoside, Lecithin, Phytosterols, Squalane, Ceramide 3,
     FMLT GotuSphere 5.0                                                        Caprylic/capric triglyceride, Butyrospermum parkii (Shea butter),
                                                                                Water
                                                                                Coenzyme-Q10, Lecithin, Phytosterols, Squalane, Ceramide 3,
     FMLT Q-10 Sphere 1.0                                                       Caprylic/capric triglyceride, Butyrospermum parkii (Shea butter),
                                                                                Water
                                                                                Coenzyme-Q10, Lecithin, Phytosterols, Squalane, Ceramide 3,
     FMLT Q-10 Sphere 5.0                                                       Caprylic/capric triglyceride, Butyrospermum parkii (Shea butter),
                                                                                Water
                                                                                Naringin, Lecithin, Phytosterols, Squalane, Ceramide 3,
     FMLT NariSphere 1.0                                                        Caprylic/capric triglyceride, Butyrospermum parkii (Shea butter),
                                                                                Water
                                                                                Quercetin, Lecithin, Phytosterols, Squalane, Ceramide 3,
     FMLT QueSphere 1.0                                                         Caprylic/capric triglyceride, Butyrospermum parkii (Shea butter),
                                                                                Water

     Natural Jeju Organic Camellia Oil                                          Camellia japonica seed oil




   10-   BioSpectrum
                                                                                               BIOSPECTRUM




Whitening
Melanin, the pigment in charge of skin and hair color, is synthesized when skin is exposed to ultraviolet
light, certain drugs or chemicals. It may also be synthesized under the existence of disease or as a
result of post-inflammatory response to trauma, chemical peels, laser therapy, or acne. Global market of
skin whitening, especially market in Asia, is growing at an unprecedented rate. Asians demand for
products to get purer look, while Europeans endeavor to reduce age spots and freckles. The general
mechanism of skin whiteners is to reduce the level of tyrosinase, to regulate the activity of tyrosinase, to
hinder the uptake and distribution of melanosomes in recipient keratinocytes, and/or to promote break
down of melanin and turnover of pigmented keratinocytes.

Most of whiteners developed by BioSpectrum, Inc. are multifunctional, meaning that beside the
whitening activity, they have other skin care activities, such as anti-aging, soothing, anti-inflammation
and/or anti-oxidation. Efficacy and safety of all of our ingredients is verified in vitro and in vivo.


                                   Whitening
        Product Name                  Anti-aging/Anti-wrinkle                                         INCI Name
                                      Phytoestrogen
                                      Soothing/Anti-inflammation/Antioxidant

     Alpha-Melight (Patented)                                                  Bisabolol ([-]-Alpha-bisabolol, >98%)

     HerbEx Acerola                                                            Malpighia glabra (Acerola) fruit extract

     HerbEx Genistein 1.0                                                      Soy isoflavones

     HerbEx Irisflavone                                                        Iris florentina root extract

     Jeju Cana (Patented)                                                      Erigeron canadensis flower extract

     Jeju Lily (Patented)                                                      Phormium tenax extract

     HerbEx Mullberry                                                          Morus alba (Mulberry) leaf extract

     HerbEx Silybum                                                            Silybum marianum extract


     HerbEx Wild yam                                                           Dioscorea villosa (Wild yam) root extract

                                                                               Arbutin, Linolenic acid, Linoleic acid, Tocopheryl acetate,
     Nano-Bright                                                               Ascorbyl palmitate, Rutin, Ubiquinone, Resveratrol,
                                                                               Lecithin, Water
                                                                               Dioscorea villosa (Wild yam) root extract, Lecithin, Butylene
     NLT DioSphere 2.0                                                         glycol, Water
                                                                               Diosgenin, Lecithin, Phytosterols, Squalane, Caprylic/capric
     FMLT DioSphere 2.0                                                        triglyceride, Butyrospermum parkii (Shea butter), Ceramide 3,
                                                                               Water
                                                                               Bisabolol, Camellia japonica seed oil, Oxalis hedysaroides
     MelaCareOil
                                                                               extract




                                                                                                                       BioSpectrum -11
BIOSPECTRUM




   Phytoestrogens: NATURAL Hormones for Women
   Phytoestrogens are a diverse group of naturally occurring plant-derived hormones. They exert almost
   the same bodily effects as does the human estrogen hormone due to their structural similarity with
   human estrogen. Researchers have been explored the nutritional role of these substances in the
   regulation of cholesterol and post-menopausal symptoms. Phytoestrogens may protect against various
   health disorders, consequently leading to optimum health conditions when the estrogen levels are
   balanced.

   Numerous clinical studies have shown that estrogen helps to preserve collagen content in skin and
   elastic properties of skin while counteracting the negative effects of collagen loss on the skin.
   Phytoestrogens help to restore and maintain skin firmness.



                                      Phytoestrogen
               Product Name             Anti-aging/Anti-wrinkle                                     INCI Name
                                        Whitening
                                        Dermatitis improvement/Anti-allergy

           HerbEx Angelica                                                    Angelica polymorpha sinensis root extract

           HerbEx Black Cohosh                                                Cimicifuga racemosa root extract

           HerbEx Genistein 1.0                                               Soy isoflavones

           HerbEx Irisflavone                                                 Iris florentina root extract

           HerbEx Kudzu                                                       Pueraria lobata root extract

           HerbEx Kwao Kreu                                                   Pueraria mirifica root extract

           HerbEx Red Clover                                                  Trifolium pratense (Clover) flower extract

           HerbEx Resverol 0.5                                                Polygonum cuspidatum root extract

           HerbEx Wild Yam                                                    Dioscorea villosa (Wild yam) root extract

                                                                              Soy isoflavones, Cimicifuga racemosa root extract,
                                                                              Polygonum cuspidatum Root extract, Pueraria lobata root
           MultiEx Phytrogen                                                  extract, Angelica Polymorpha sinensis root extract, Punica
                                                                              granatum extract, Trifolium pratense (Clover) flower extract,
                                                                              Pueraria mirifica root extract

           NLT GeniSphere 2.0                                                 Soy isoflavones, Lecithin, Butylene glycol, Water

                                                                              Pueraria lobata root extract, Lecithin, Butylene glycol,
           NLT PueSphere 1.0
                                                                              Alcohol, Water
                                                                              Soy isoflavones, Lecithin, Phytosterols, Beta-sitosterol,
           FMLT GeniSphere 5.0                                                Ceramide 3, Caprylic/capric triqlyceride, Butyrospermum
                                                                              parkii (Shea butter), Water, Alcohol




   12-   BioSpectrum
                                                                                     BIOSPECTRUM



Anti-Inflammation/Antioxidant/Soothing
Inflammatory skin diseases are the most common problems found in dermatology. They come in many
forms, from occasional rashes, accompanied with skin itching and redness, to chronic conditions, such
as dermatitis (eczema), rosacea, seborrheic dermatitis, and psoriasis.

Skin inflammation can be characterized as acute or chronic. Acute inflammation is caused by exposure
to UV radiation, ionizing radiation, allergens, or chemical irritants (soaps, hair dyes, etc.). This type of
inflammation is typically resolved within 1 to 2 weeks accompanied by little tissue destruction. In
contrast, chronic inflammation results from a sustained immune cell-mediated inflammatory response
within the skin itself. This type of inflammation lasts long and potentially causes significant and serious
tissue destruction. Our products may offer solution to prevent and cure inflammatory responses in
troubled skins.



                                      Anti-inflammation
         Product Name                 /Antioxidant/Soothing                                INCI Name
                                         Whitening

      HerbEx Centella                                                 Centella asiatica extract

      HerbEx Curcuma                                                  Curcuma longa (Turmeric) root extract

      HerbEx Ginkgo                                                   Ginkgo biloba leaf extract

      HerbEx Grape Seed                                               Vitis vinifera (Grape) seed extract

      HerbEx Green Tea                                                Camellia sinensis leaf extract

      Jeju Artemis                                                    Artemisia princeps extract

      Jeju Lemon (Patented)                                           Citrus medica limonum (Lemon) fruit extract

      Jeju Hounia (Patented)                                          Houttuynia cordata extract

      Jeju Mentha (Patented)                                          Mentha arvensis extract

      Jeju Pinus (Patented)                                           Pinus pinaster bark extract

      HerbEx Licorice                                                 Glycyrrhiza glabra (Licorice) root extract

      HerbEx Mullberry                                                Morus alba (Mulberry) leaf extract

      HerbEx Pomegranate                                              Punica granatum extract

      HerbEx Portulaca                                                Portulaca oleracea extract

      HerbEx Schizandra                                               Schizandra chinensis fruit extract

      HerbEx Silybum                                                  Silybum marianum extract

      HerbEx Skullcap                                                 Scutellaria baicalensis root extract

      HerbEx Willow                                                   Salix alba (Willow) bark extract




                                                                                                             BioSpectrum -13
BIOSPECTRUM




   Anti-Inflammation/Antioxidant/Soothing
                                Anti-inflammation
                                /Anti-Oxidant/Soothing
                                  Anti-aging/Anti-wrinkle
           Product Name           Natural humectant                                          INCI Name
                                  Skin immune system regulation
                                  Dermatitis improvement/Anti-allergy
                                  Anti-microbial activity

                                                                        Glycyrrhiza glabra (Licorice) root extract, Camellia sinensis
                                                                        leaf extract, Rosmarinus officinalis (Rosemary) leaf extract,
     MultiEx BSASM (Patented)                                           Centella asiatica extract, Chamomilla recutita (Matricaria)
                                                                        flower/leaf extract, Scutellaria baicalensis root extract,
                                                                        Polygonum cuspidatum root extract

                                                                        Glycyrrhiza glabra (licorice) root extract, Artemisia asiatica
     MultiEx Rosanic                                                    extract, Ginkgo biloba leaf extract, Centella asiatica extract,
                                                                        Vaccinium corymbosum (Blueberry) fruit, Rosa canina fruit
                                                                        oil

     NLT CentSphere 1.0                                                 Centella asiatica extract, Lecithin



     NLT DPGSphere 2.0                                                  Dipotassium glycyrrhiziate, Lecithin, Butylene Glycol



     NLT OASphere 1.0                                                   Oleanolic Acid, Lecithin, Butylene glycol


     NLT UrSphere 2.0                                                   Ursolic acid, Lecithin, Water


                                                                        Glycyrrhiza glabra (Licorice) root extract, Camellia sinensis
                                                                        leaf extract, Rosmarinus officinalis (Rosemary) leaf extract,
                                                                        Centella asiatica extract, Chamomilla recutita (Matricaria)
                                                                        flower/leaf extract, Scutellaria baicalensis root extract,
     FMLT BSASM                                                          Polygonum cuspidatum root extract, Lecithin, Phytosterols,
                                                                        Squalane, Ceramide 3, Caprylic/capric triglyceride,
                                                                        Butyrospermum parkii (Shea butter), Butylene glycol,
                                                                        Alcohol, Water


                                                                        Aloe barbadensis leaf extract, Berberis vulgaris root extract,
                                                                        Centella asiatica extract, Dioscorea villosa (Wild yam) root
                                                                        extract, Glycyrrhiza glabra (Licorice) root extract,
     FMLT PsoriaSolve                                                   Polypodium leucotomos leaf extract, Pinus strobus bark
                                                                        extract, Lecithin, Phytosterols, Squalane, Ceramide 3,
                                                                        Caprylic/capric triglyceride, Butyrospermum parkii (Shea
                                                                        butter), Water


                                                                        Dioscorea villosa (Wild yam) root extract, Glycyrrhiza
                                                                        glabra (Licorice) root extract, Pyridoxine HCl, Zinc PCA,
     FMLT SeboCure                                                      Azelaic acid, Niacinamide, Soy isoflavones, Lecithin,
                                                                        Phytosterols, Squalane, Ceramide 3, Caprylic/capric
                                                                        triglyceride, Butyrospermum parkii (Shea butter), Water




   14-   BioSpectrum
                                                                                                   BIOSPECTRUM




Dermatitis Improvement/Anti-Allergy
The skin immune system (SIS) embodies the set of immune responses associated with cellular and
molecular elements of the human integument. They act together as the physiological immune defense
system of skin. There are numerous abnormal regulations of SIS. Atopic dermatitis is a syndrome with
apparent abnormal regulation in skin immune system. The skin of a patient with atopic dermatitis reacts
abnormally and easily to irritants, food, and environmental allergens, and becomes red, flaky and very
itchy. It also becomes vulnerable to surface infections caused by bacteria. Those abnormalities on
atopic skin can be normalized by the immuno-modulators from natural plants.



                              Dermatitis improvement /
                              Anti-allergy
      Product Name              Soothing/Anti-inflammation/Antioxidant                             INCI Name
                                Skin immune system regulation


  HerbEx Chamomile                                                       Chamomilla recutita (Matricaria) flower/leaf extract


  HerbEx Rosemary                                                        Rosmarinus officinalis (Rosemary) leaf extract


  HerbEx Silybum                                                         Silybum marianum extract


  HerbEx Skullcap                                                        Scutellaria baicalensis root extract


  HerbEx Willow                                                          Salix alba (Willow) bark extract


  NLT CentSphere 1.0                                                     Centella asiatica extract, Lecithin


                                                                         Glycyrrhiza glabra (Licorice) root extract, Camellia sinensis leaf
                                                                         extract, Rosmarinus officinalis (Rosemary) leaf extract, Centella
                                                                         asiatica extract, Chamomilla recutita (Matricaria) flower/leaf extract,
 FMLT BSASM                                                              Scutellaria baicalensis root extract, Polygonum cuspidatum Root
                                                                         extract, Lecithin, Phytosterols, Squalane, Ceramide 3, Caprylic/capric
                                                                         triglyceride, Butyrospermum parkii (Shea butter), Butylene glycol,
                                                                         Alcohol, Water



                                                                         Aloe barbadensis leaf extract, Berberis vulgaris root extract, Centella
                                                                         asiatica extract, Dioscorea villosa (Wild yam) root extract,Glycyrrhiza
                                                                         glabra (Licorice) root extract, Polypodium leucotomos leaf extract,
 FMLT PsoriaSolve
                                                                         Pinus strobus bark extract, Lecithin, Phytosterols, Squalane,
                                                                         Ceramide 3, Caprylic/capric triglyceride, Butyrospermum parkii
                                                                         (Shea butter), Water




                                                                                                                          BioSpectrum -15
BIOSPECTRUM




   Skin Immune System Regulation
   Some ingredients from PLANTs can help boost your skin°Øs immunity. Like other living organisms,
   PLANTs provide chemicals that are essential for our lives, such as vitamins, trace minerals, enzymes,
   and proteins. These elements can assist the immune battles to fight off the skin problems such as
   blemishes, wrinkles, redness or blotchy skin and/or aged spots. Some dermatologists are now
   beginning to suspect that these problems in the skin are due to breakdowns of the skin immune system.
   Even though more researches are needed, recently certain ingredients have already been reported as a
   part of new family of immune boosters for the skin immune system. Here's a quick look of our
   ingredients that may protect skin from external attacks and may support immune cells to fight against
   harmful invaders.



                                     Skin immune system regulation
                                       Anti-aging/Anti-wrinkle
             Product Name                                                                             INCI Name
                                       Anti-inflammation/Antioxidant/Soothing
                                       Dermatitis improvement/Anti-allergy

           HerbEx Echinaceae                                                    Echinacea angustifolia extract


           HerbEx Korean Ginseng                                                Panax ginseng root extract


           HerbEx Shiitake                                                      Lentinus edodes extract


           HerbEx Siberian Ginseng                                              Acanthopanax senticosus (Eleuthero) root extract


           Yeast Beta-Glucan                                                    Yeast beta-glucan

                                                                                Glycyrrhiza glabra (Licorice) root extract, Camellia
                                                                                sinensis leaf extract, Rosmarinus officinalis (Rosemary)
                                                                                leaf extract, Centella asiatica extract, Chamomilla recutita
                                                                                (Matricaria) flower/leaf extract, Scutellaria baicalensis root
           FMLT BSASM                                                           extract, Polygonum cuspidatum root extract, Lecithin,
                                                                                Phytosterols, Squalane, Ceramide 3, Caprylic/capric
                                                                                triglyceride, Butyrospermum parkii (Shea butter), Butylene
                                                                                glycol, Alcohol, Water

                                                                                Aloe barbadensis leaf extract, Berberis vulgaris root extract,
                                                                                Centella asiatica extract, Dioscorea villosa (Wild yam) root
                                                                                extract, Glycyrrhiza glabra (Licorice) root extract,
           FMLT PsoriaSolve                                                     Polypodium leucotomos leaf extract, Pinus Strobus bark
                                                                                extract, Lecithin, Phytosterols, Squalane, Ceramide 3,
                                                                                Caprylic/capric triglyceride, Butyrospermum parkii
                                                                                (Shea butter), Water




   16-   BioSpectrum
                                                                                           BIOSPECTRUM



Biologically Active Peptides
Biologically active peptides are small building blocks of proteins, which mostly act as messengers in
human body. By improving cellular communications, they can stimulate a wide range of bioactivities,
including skin regeneration. When peptides are linked with penetration enhancers, they easily penetrate
into skin and exert cellular effects. The cosmetic use of peptides is actively investigated, and as a
matter of fact, there are peptides that are known to provide tremendous variety of functions important to
moisturizers, anti-aging cosmetics or cosmeceuticals, and hair conditioners. Incorporating our NATURE
or PLANT-derived peptides in skin care products will promise to elicit beneficial skin care effects without
any irritation and sensitization.



                               Biologically active peptides
      Product Name                                                                        INCI Name
                                  Anti-aging/Anti-wrinkle

      HerbEx Flexin                                           Yeast extract

      HerbEx HealUp                                           Hydrolyzed lupine Protein

      HerbEx Silk                                             Hydrolyzed silk

      HerbEx SoftSil                                          Triticum vulgare (Wheat) seed extract

      HerbEx Soy peptide                                      Glycine soja (Soybean) protein


      AcePep                                                  Acetyl hexapeptide-8, Butylene glycol, Water



                                                              Palmitoyl pentapeptide-4, Butylene glycol, Glycerin,
      BsPep                                                   Polysorbate-20, Water


                                                              Palmitoyl tetrapeptide-7, Polysorbate 20, Butylene glycol,
      CytoPep
                                                              Xanthan gum, Water




                                                                                                                BioSpectrum -17
BIOSPECTRUM




   NATURAL Humectants
   Younger people tend to prefer lighter moisturizing products than older generations. This is because the
   younger is capable to retain water more and to produce sebum more. Humectants (hygroscopic
   substances) protect the skin from dryness, provide moisture, add resiliency, and help the skin to look
   young and healthy. The humectants can moisturize dry skin with a proper moisturizing potency.
   The humectants can prevent further dehydration by retarding the escape of water from surface tissues
   and by restoring the moisture level in deeper tissues.



                                          Natural humectants
               Product Name                                                              INCI Name
                                             Whitening

         Acer Maple Water                                          Acer Mono Sap


         HerbEx Chitosan                                           Chitosan

         HerbEx Chondroitin Sulfate                                Sodium chondroitin sulfate

         HerbEx Fructovan                                          Fructan

         HerbEx Hyaluron                                           Sodium hyaluronate


                                                                   Sodium PCA, Trehalose, Sorbitol, Glycerin, Panthenol,
         MultiEx Humid-Max                                         Sodium hyaluronate, Water


         Waterin                                                   Saccharide isomerate, Water




   18-   BioSpectrum
                                                                                                 BIOSPECTRUM




Anti-Microbial Activity
Pathogens, such as bacteria and viruses, enter the body through breaks in our skin, or when they find a
rich environment for their propagation such as in clogged and broken sebaceous glands within the hair
follicles (acne infections). As they gain access to the blood stream, they induce increased systemic
immune responses. Increased responses in immune systems interrupt the repair and healing process of
skin that has been damaged, and interfere the normal lay down of our skin cells. Additionally, they may
cause erythema (redness) around the affected sites, as well as some superficial edema (swelling) and
an excited production and lay down of collagen. We proudly offer our excellent NATURAL antibiotics,
which are originated from PLANTs, to fight against skin problems caused by microorganisms.



                            Anti-microbial activity
     Product Name             Biologically active peptides                                       INCI Name
                              Soothing/Anti-inflammation/Antioxidant

  HerbEx Allium                                                        Allium sativum (Garlic) bulb extract


  HerbEx Bloodroot                                                     Sanguinaria canadensis rhizome/root extract


  HerbEx Burdock                                                       Arctium lappa root extract


  HerbEx MagnoSoother                                                  Magnolia kobus bark extract


  HerbEx Propolis                                                      Propolis extract

                                                                       Magnolia kobus bark extract, Camellia sinensis leaf extract, Citrus
  MultiEx Magnotics                                                    grandis (Grapefruit) fruit extract, Thujopsis dolabrata branch extract

                                                                       Magnolia biondii bark extract, Propolis extract, Camellia sinensis leaf
  MultiEx Naturotics                                                   extract, Thujopsis dolabrata branch extract, Citrus grandis
  (Patented)                                                           (Grapefruit) fruit extract, Chamomilla recutita (Matricaria) flower/leaf
                                                                       extract, Salix alba (Willow) bark extract


                                                                       Azelaic acid, Lecithin, Phytosterols, Squalane, Ceramide 3,
  FMLT AzelaSphere 10.0                                                Caprylic/capric triglyceride, Butyrospermum parkii (Shea butter),
                                                                       Water


                                                                       Dioscorea villosa (Wild yam) root extract, Glycyrrhiza glabra
                                                                       (Licorice) root extract, Pyridoxine HCl, Zinc PCA, Azelaic acid,
  FMLT SeboCure                                                        Niacinamide, Soy isoflavones, Lecithin, Phytosterols, Squalane,
                                                                       Ceramide 3, Caprylic/capric triglyceride, Butyrospermum parkii
                                                                       (Shea butter), Water




                                                                                                                        BioSpectrum -19
BIOSPECTRUM




   Chemoprevention
   The rate in pathogenesis of skin cancer has increased dramatically during the past two decades, mainly
   because of cumulative exposure to the ultraviolet rays emitted by the sun. Skin cancer is a disease in
   which malignant cancer cells are found in the outer layers of skin.

   Prevention of cancer by natural and synthetic non-toxic chemo-preventive agents has become a major
   research area in the past 15 years. The naturally occurring chemo-preventive agents from the herbal
   medicine and edible plants can be evaluated in a variety of bioassays and identified for their activity as
   cancer preventive agents. Some of our NATURAL ingredients have showed significant cancer chemo-
   preventive capabilities in various carcinogen-induced cancer models.


                 Product Name                 Chemoprevention                                   INCI Name

          HerbEx Broccoli                                                   Brassica oleracea italica (Broccoli) extract

          HerbEx Ginger                                                     Zingiber officinale (Ginger) root extract




   Hair and Scalp Care
   The hair follicle is one of a few human tissues containing stem cells. The stem cells are interspersed
   within the basal layer of the outer root sheath and in an area called the bulge. From this reservoir, stem
   cells migrate to hair matrix and start to divide and differentiate. Their behavior is controlled by numerous
   cytokines produced by the dermal papilla cells. Dermal papilla cells and cells from the inner and outer
   sheaths of the follicle from androgen-dependent hairs have receptors for androgens in their cytoplasm
   and nucleus. Androgens indirectly control hair growth by influencing the synthesis and release of
   cytokines from the dermal papilla cells.

   Cosmetic ingredients affecting hair growth belong to one of the following groups: cell stimulators, anti-
   androgens and ingredients acting on potassium channels. Further development of active ingredients
   specific to certain steps in the process of hair growth will enable more successful therapy of hair growth
   disorders.


                 Product Name                 Hair and scalp care                             INCI Name

          HerbEx Polygala                                            Polygala tenuifolia root extract




   20-   BioSpectrum
         BioSpectrum, Inc.
                   Global Network
      #America                                 #Asia
      United States                            Japan
      DKSH North America, Inc.                 GSI Creos Corporation
      Tel. (+1) 973-819-5516                   Tel. (+81) 3-5211-1814 (Tokyo)
      Fax.(+1) 973-810-5518                         (+81) 6-6944-2621 (Osaka)
      Email. roy.heckel@dksh.com               Fax.(+81) 3-5211-1929 (Tokyo)
                                                    (+81) 3 6944-9662 (Osaka)
      #Europe                                  Email. cosme@gsi.co.jp

      United Kingdoms                          Taiwan
      DKSH Great Britain Limited               Fairlink Trading Co., Ltd
      Tel. (+44) 20-8879-5511                  Tel. (+886) 2 2505 1305
      Email. imogen.marsh@dksh.com             Email. fairlink@ms29.hinet.net

      Germany                                  Thailand
      MAWI Industrieagentur OHG.               Diethelm Ltd.
      Tel. (+49) 6236-4498-00                  Tel. (+66) 2-790-4000
      Fax.(+49) 6236-4498-07                   Fax.(+66) 2-332-0193
      Email. rwillmann@mawi-industrie.de       Email. jutamanee.p@dksh.com

      France                                   Berli Jucker Specialties Ltd.
      COMERCIAL QUIMICA MASSO                  Tel. (+66) 2-367-1212
      Tel. (+33) 478-6400-33                   Fax.(+66) 2-381-4548
      Fax.(+33) 478-8307-29                    Email. AmonratS@bjc.co.th
      Email. gcombes@cqmasso.com
                                               Malaysia
      Spain                                    Avares (M) Sdn. Bhd.
      SAEQUIM ESPECIALIDADES S.L.              Tel. (+60) 3-8961-2559
      Tel. (+34) 93-475-1680                   Fax.(+60) 3-8945-0780
      Fax.(+34) 93-475-1681                    Email. inquiry@avares.com.my
      Email. cosmetica@saequim.com
                                               China
      Italy                                    Shanghai Shintop Chemical Ltd.
      DKSH Italia S.r.l                        Tel. (+86) 21-64120046 (Shanghai)
      Tel. (+39) 2-3070-1832                        (+86) 20-87382349 (Guangzhou)
      Fax.(+39) 2-3070-1834                    Fax.(+86) 32-6413-0702 (Shanghai)
      Email. alberto.montano@dksh.com               (+86) 20-8738-6210 (Guangzhou)
                                               Email. charley_ren@163.com
      Greece
      Xoxacos Chemical (Chemix SA)             Philippines
      Tel. (+30) 210-6034-500                  Eunice Inc.
      Fax.(+30) 210-6034-861                   Tel. (+63) 2-932-7845
      Email. pc-pharma@chemix.gr               Fax.(+63) 2-632-7354
                                               Email. eiregulatory@euniceinc.ph
      Poland
      DKSH Switzerland Ltd. Poland             Israel
      Tel. (+48) 22-646-4239                   Lanir Ltd.
      Fax.(+48) 22-848-7640                    Tel. +972 3 5493753
      Email. violetta.komorska@dksh.com        Email. yafitdov@bezeqint.net

                                               India
                                               Mascot
                                               Tel. (+91) 22-66546820
                                               Fax.(+91) 22-6654-6821
                                               Email. ranjit@mascot.in




101-701 SK Ventium, 522 Dangjeong-dong, Gunpo-si, Gyeonggi-do, 435-776, Republic of Korea
     Tel. +82 31 436 2090~3 Fax. +82 31 436 0620      Email. info@biospectrum.com

                         www.biospectrum.com

				
DOCUMENT INFO
Shared By:
Categories:
Stats:
views:180
posted:7/17/2010
language:English
pages:23
Description: file p Sodium-PCA