ELIZABETH GILBERT • •• •• StoP) C;rg;ys \\;Ub aPlll! Me\t ~-'aL \ rill a baser! .......... _.. And 12 other fantastic possibilities , ~ that might be fully realized by 2020. BY JENNY BAILLY r-r en years ago. we were Just starting to hear buzz about Botox. Lasers seemed totally sci-fl . And you probably didn't . think you'd soon be uSing clear plastic strips to bleach your teeth at home ;;0 what innovations will the next decade bring? Will you be tightenillg YO'J( skin vvith a wand? Not quite. But you may be erasing lines with a topical gel. or slimming your love handles in one afternoon. without a single incision. We canvassed dermatologists. plastic surgeons. dentists. and chemists about what's ahead. and found hat the future is looking bright-and very beau lful P HOTOG RA PliS L ClAI lAY In 2020 dermatologists probably • won't be plumping up fine lines It sounds too good to be true. but it may seen as much as three inches." With the Injectable hyaluronic acid soon be a reality: Many dermatologists Another new body-contouring option is gels they use today. A few doctors and plastic surgeons are confident that in Zeltlq, a machine that uses intense cold to are already using a patient's own the coming years they'll be able to destroy fat cells (which are more vulnerable blood to create a protein-rich Researchers are in hot pursUit eliminate unwanted fat painlessly. without to freezing temperatures than surrounding solution that is injected into the skin of a "cure" for gray hair-and the invasiveness and risks of liposuction. tissue). Like the ultrasound treatment, Zeltlq to fill wrinkles and stimulate they're getting closer. A study One new technology uses high-intensity requires no needles, incisions, anesthesia, collagen production. It's jUst a hint of published last year showed The sun does a number on your focused ultrasound waves to penetrate the or recovery time. It's already FDA approved what's to come: "In a few years, that gray is caused by hydrogen skin: dark spots, wrinkles .•. not ski n and break up the fat cells that lie to cool the skin during other dermatologic we'll actually be able to use a peroxide and other ceU-damaging to mention potential cancers. about three-quarters of an inch beneath the procedures, and some doctors are starting patient's own skin tissue as the basis molecules that build up as we The best protection against aU of surface. Once these cells are destroyed. to use it off-label to red uce fat. "These for a custom-tailored filler that age, bleaching color from the this damage is sunscreen. And they are eliminated from the body (some technologies are still In the early stages, but will Ideally last longer-with no hair. The absence of an enzyme it Will soon be more powerful. In are metabolized as calories and the rest they will be perfected over the next decade possibility of allergy or rejection," called catalase allows these the next several years, the FDA are processed through the liver as waste. and we will finally have the ability to says Ranella Hirsch, MD, assistant molecules to accumulate, but will likely approve a proposal along with normal dietary fats). A machine eliminate fat without surgery," says Sadlck. clinical professor of dermatology EXT Life Sciences, a Michigan- reqUiring sunscreen bottles to that has harnessed this technology. ig B caveat: UltraShape and Zeltiq are not at Boston University School carry an SPF value (which based biotechnology company, 'UltraShape, is currently cleared for use in deSigned to remove large volumes offat; of Medicine. believes it has found a chemical denotes protection only from 57 countries, and its manufacturer is doctors stress that the machines are compound that can restore UVB rays) and a designation pursuing FDA approval. The UltraShape most effective on areas of "localized fat," catalase and thus return hair to of its UVA protection level. "The treatments are said to be relatively like love handles or back bulges. its original color. The compan~ is new rules will ensure that painless-"just a slight t ingly sensation," working to incorporate the sunscreen manufacturers are says Canadian dermatologist Mark LUpin, ingredient Into leave-in providing adequate protection MD. Three treatments, spaced two weeks conditioners and serums, says, from UVA rays," says Steven apart, are usually required, with noticeable cofounder Stanley Ter!ecky. pKI'>, Wang, MD, director of results seen within a month after each. professor of pharmacoLI3t;y'31 dermatologic surgery and "On average, patients ultimately see about dermatology at Memorial Sloan- Wayne State un'Il.~r'SltYA~ho·o l a two-inch reduction In circumference of Medicine. And-a,GToiilS'the Kettering Cancer Center at in the treated area," Lupin says. "And we've Atlantic, rOrealts I!!a Is-based Basking Ridge, New Jersey. Once the proposed guidelines go into hair biology res a.af!:1~ 'gIOup effect, the FDA will also likely recently IdentIfied 11 paIr af green-light Tinosorb, a sunscreen genes that may d~rnilnet~e Ingredient that absorbs a wide longevity of the cetis-tlilatg:i,ve spectrum of UVA and UVB rays hair its color. rOn~al Se'tent,lsts and is currently approved in are hard at work developing Europe and South America. a treatment (either a pill or a topical formula) to block the progressive decline in these color-giving cells and stop- or at least slow-the graying process, says group director Bruno Bernard, PhD. For details see Shop Guide. The past year has given us some effective at-home laser hair-removal options (we've seen impressive results from the Silk'n SensEpil, THE BEAUTY OF STEM CELLS $499, and the Tria Laser Hair Removal System, $S95)-but hair-free A stem cell is an exquisitely blank slate-it has the potential to become a nerve, a muscle, a retina. Or... breast legs are just the beginning. "In the not too distant future, lasers tissue, a hair follicle, elastin. Now that researchers are beginning to tap into these cells' programmable potential-to treat cancer, and intense pulsed light machines that remove pigment, soften paralysis, cardiac disease (see page 152 for more on the cells' promise in rebuilding damaged hearts)-the science lines, and treat acne will be Sitting on bathroom counters will inevitably make its way into the cosmetics industry. (Remember, Botox was first developed to treat muscle spasms of next to our toothbrushes: says Tina Alster, MD, clinical professor the eye, and the hyaluronic acid in facial fillers was used for lubricating joints.) Stem cells could potentially creat~ new of dermatology at Georgetown University Medical Center In collagen, grow new hair, and restore skin color in people with pigmentation disorders, says David Goldberg, MD, director Washington, D.C. First up: An at-home skin-resurfacing laser of laser research at Mount Sinai School of Medicine. Stunning prospects, aren't they? will be available for purchase in doctors' offices next year. The device pinpoints small areas of skin With every treatment to gradually improve discoloration and fine lines.