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American Society for Laser Medicine and Surgery Abstracts Body contouring
American Society for Laser Medicine and Surgery Abstracts combined 1064/1320 nm multiplex system however caution shouldâ¨be used when exceeding external skin temperatures of 40 degreesâ¨Celsius to avoid unwanted thermal burns. Future studiesâ¨comparing the end temperature and wavelengths independentlyâ¨may help to uncover the optimal system needed for skinâ¨contracture. 43 was more readily observed in subjects with modest fat bulges.â¨Further studies of fat reduction effects in other anatomical areasâ¨with optimized treatment parameters are warranted. 130 STUDY USING EXTERNAL FOCUSEDâ¨ULTRASOUND FOR BODY CONTOUR WITH THEâ¨NEW 1 HZ HAND PIECE COMPARED TO THE 3 HZâ¨HANDPIECE 129 A PROSPECTIVE CLINICAL STUDY OFâ¨NONINVASIVE CRYOLIPOLYSIS FORâ¨SUBCUTANEOUS FAT LAYERâ¨REDUCTIONâINTERIM REPORT OFâ¨AVAILABLE SUBJECT DATA Guilherme Almeida, Leticia Almeida,â¨Andrezza Facci, Elaine Marques, Marcia Paes, Thais Notarangelli Hospital Sirio libanes, Sao Paulo, Brazil Clinica Dermatologica Dr Guilherme de Alrrieida, Sao Paulo, Brazil Jeffrey Dover, Jay Burns, Syd Coleman, Richard Fitzpatrick, Jerome Garden, David Goldberg, Roy Geronemus, Suzanne Kilmer,â¨Flor Mayoral, Robert Weiss, Brian Zelickson,â¨Elizabeth Tanzi Background: We describe our experience in treating bodyâ¨contouring using the technologies of focused ultrasound (Contourâ¨I- Ultrashape, Tel Aviv, Israel), comparing the results obtainedâ¨applying 1 Hz pulse hand piece to the 3 Hz. Study: After two years of experience with the Contour I-â¨Ultrashape device, in last 12 months we performed 354â¨treatments of 83 patients with localized fat tissue for the purposeâ¨of this study as mono therapy. 85% women and 14% men, aged 23Â¬â¨65 were treated. All patients underwent 3 sessions with at leastâ¨800 pulses with a 2 weeks interval. Areas treated: abdomen (33%) Yale University, Chestnut Hill, MAâ¨UTSouthwestern, Dallas, TXâ¨New York, NY La Jolla Cosmetic Surgery Centre, San Diego, CAâ¨Northwestern University, Chicago, ILâ¨Skin and Laser Specialists ofNY/NJ, New York, NYâ¨Laser & Skin Surgery Center, New York, NYâ¨Laser & Skin Medical Group, Inc., Sacramento, CAâ¨Miami, FL Johns Hopkins, Hunt Valley, MDâ¨Zel Skin & Laser Specialists, Edina, MN Washington Institute of Dermatology: Laser Surgery, Washington, flanks (40%), outer thighs (14%), inner thighs (3%), knees (3%),â¨axillaris fold (3%), and buttock's fold (4%). 63 (76%) were treatedâ¨with the 3 Hz and 20 ( 24%) with the new 1 Hz. All patients wereâ¨pictured by Vectra 3D system (Canfield, NJ, USA). Efficacy determined by circumference measurements, 3D pictures andâ¨patient satisfaction. Results: We measure all patients, that showed significantâ¨reduction with at least 1,2 cm in circumference each session andâ¨1.8 cm average, showed also on the 3D pictures and satisfactionâ¨related to the improvement on the appearance of body silhouetteâ¨was 86%. Pain was present in 7 patients (35%), even with cold oilâ¨and lowering the level of energy. Other side effects referred in allâ¨patients were mild transient erythema, 2 (1,6%) cases ofâ¨epidermolysis and without any other major side effect.â¨Conclusion: Non invasive body contouring by focused ultrasoundâ¨is safe and efficient for localized fat tissue with both, 1 and 3 Hzâ¨devices. We achieved with the new 1 Hz hand piece the sameâ¨results and safety issues. As expected, the new hand pieceâ¨optimized the treatment time in 30%. DC Background: Published animal studies and unpublished controlled human studies have demonstrated that cryolipolysisâ¨(cold-induced apoptotic fat cell death) is safe, well tolerated, andâ¨capable of reducing the thickness of the subcutaneous fat layerâ¨without damage to the overlying skin or associated structures.â¨This study evaluated cryolipolysis for fat layer reduction from theâ¨flanks (love handles) and back (back fat pads) when used by.â¨clinicians in an environment representative of routine clinicalâ¨practice. Study: This multi-center, prospective, non-randomized, IRB-â¨approved study enrolled male and female subjects > 18 years ofâ¨age with clearly visible fat on the flank or back appropriate forâ¨treatment with cryolipolysis. Cooling was applied by a prototypeâ¨device to the treatment area using pre-programmed treatmentâ¨profiles that control the rate of heat extraction and treatmentâ¨duration. A contralateral untreated area (e.g., the opposite flankâ¨or portion of the back) was maintained as a control. Efficacy wasâ¨evaluated by ultrasound measurement of fat layer reduction,â¨comparison of pre and post-treatment photographs and physicianâ¨assessment. 131 CELLULITE TREATMENT WITHâ¨PHOTOMOLOGYÂ® TECHNOLOGY Nathalie Fournier, Michail Pankratov, Anne Sophie Aubree, Serge Mordon Center Laser Dermatology Phlebology, Clapiers, Franceâ¨Eleme Medical, Merrimack, NHâ¨INSERM U703-Lille University Hospital, Lille, Franceâ¨Background: PhotomologyÂ® technology combining dual-bandâ¨fight with mechanical massage and suction provides moderateâ¨temperature elevation and mechanical manipulation thatâ¨improves local blood circulation, metabolic activity includingâ¨lypolysis and stimulates chemical reactions. Study: SmoothShapesÂ® system uses 915 nm (10 W) laser fightâ¨that is preferentially absorbed in lipids with temperature Results: Based on interim results from 32 subjects, photographic,â¨ultrasound and physician assessment confirm that cryolipolysisâ¨results in a visible contour change in a msg'ority of subjects.â¨Ultrasound measurements taken on a subset of 10 subjectsâ¨demonstrated a fat layer reduction in 100% of these subjects withâ¨an average reduction of 22.4% at four months post-treatment.â¨Subjects presenting with modest fat bulges had the best cosmeticâ¨results. There were no device related adverse events reported.â¨Conclusion: Selective oyolipolysis results in reductions inâ¨subcutaneous fat without damage to the surrounding tissues.â¨While all subjects for whom ultrasound images were obtainedâ¨showed a significant reduction in fat layer, cosmetic improvement American Society for Laser Medicine and Surgery Abstracts University of California, Irvine, CAâ¨Primaeva Medical, Inc., Pleasanton, CAâ¨Premier Plastic Surgery, San Mateo, CAâ¨Stanford University, Stanford, CAâ¨Background: Noninvasive bipolar and monopolarâ¨radiofrequency (RF) deep dermal heating devices have previouslyâ¨been described. The thermal effects of Renesisâ¢, a novelâ¨minimally invasive RF device, on human skin in vivo wereâ¨characterized for the first time. Study: The device was configured to operate in bipolar modeâ¨delivering energy directly within the dermis using 5 micro-needleâ¨electrode pairs with real-time feedback of tissue temperature forâ¨treatment control. Superficial cooling was achieved using a Peltierâ¨device. A range of pulse durations between 1 and 25 seconds, andâ¨lesion temperatures between 60 and 80Â°C were tested in vivo onâ¨15 human subjects. Thermal effects were assessed histologicallyâ¨using either hematoxylin & eosin (H&E) or nitroblue-â¨tetrazoliumchloride (NBTC) staining. Results: The investigational bipolar RF device deliveredâ¨controlled heating within dermal tissue. Histological stainingâ¨with H&E revealed the presence of zones of denatured collagenâ¨within the reticular dermis. Fractional lesions separated by zonesâ¨of sparing as well as contiguous lesion patterns wereâ¨demonstrated. Histological staining with H&E and NBTCâ¨revealed sparing of adnexal structures and adipose tissue.â¨Conclusion: A novel fractional RF device utilizing a minimallyâ¨invasive bipolar micro-needle delivery system for the treatment ofâ¨human tissue was developed. To our knowledge, this is the firstâ¨report to describe use of a direct real-time temperature andâ¨impedance feedback system to control energy delivery during deepâ¨dermal heating. Treatment of 15 human subjects illustrated theâ¨controlled creation of dermally located thermal coagulation zones,â¨known as radiofrequency thermal zones. We discovered thatâ¨varying the pulse length allowed for fractional sparing ofâ¨epidermal, dermal, and adipose tissue, as well as vasculature andâ¨key adnexal structures. Our findings provide novel insightsâ¨regarding the concept of fractional treatment with an extension ofâ¨the definition to include sparing of all skin structures vital to theâ¨wound healing process. 44 elevation for fat liquefaction and 650 nm (1W) light for changes inâ¨adipocytes permeability. Suction and massage assist inâ¨evacuation of liquefied fat from intracellular space. Volunteersâ¨with mild-moderate cellulite received 8 to 12 twice-a-weekâ¨treatments on one thigh, while the contra-lateral thigh served as aâ¨control. Results: 30 female patients, phototypes I to V, mean age 40 years,â¨underwent the treatment. The mean circumferential reduction onâ¨the high level of the thigh was 1.58 cm after 5 sessions, 2.44 cmâ¨after 8 sessions, 1.4 cm at one month after the last session on theâ¨treated thigh. In comparison, the non treated side hadâ¨circumferential reduction of 0.55 cm at 5 treatments, 0.01 cm atâ¨8 treatments, and 0.81 cm at one month after the last session. Atâ¨3 months results were stable or decreasing on some patients.â¨Results at 6 months were still interesting but showed necessity ofâ¨performing new sessions. Patient's weights were stable withoutâ¨any diet. Patients' high level of satisfaction was due to the comfortâ¨and the efficacy of the treatment. Conclusion: Photomology is a comfortable treatment and hadâ¨high percentage of responders with improvement in cellulite. 132 SAFETY STUDY OF TRANSCUTANEOUSâ¨FOCUSED ULTRASOUND FOR NON-INVASIVEâ¨SKIN TIGHTENING IN ASIANSâ¨Nicola P.Y. Chan, Samantha Y. Shek, Carol S. Yu,â¨Henry H. Chan The University of Hong Kong, Hong Kong SAR, Chinaâ¨background: The objective of this study is to determine theâ¨safety of a novel focused ultrasound device (Ulthera System) inâ¨the treatment of facial skin laxity in Asians. Study: The patients received one to two full-face treatments withâ¨the transcutaneous focused ultrasound device. Three transducers * (7.5 MHz, 3.0 mm depth; 7.5 MHz, 4.5 mm depth; 4.0 MHz, 4.5 mm depth) were used to deliver a single pass of microthermal areas ofâ¨coagulation without any topical anaesthetics. Standardizedâ¨photos were taken with the Canfield Visia CR systemÂ® and allâ¨patients were clinically assessed for adverse effects up to 6 mdnthsâ¨post treatment. Subjective assessments were also evaluated withâ¨patient questionnaires. Results: 49 Chinese patients (skin type III-TV, mean age 53.3)â¨completed a total of 58 treatment sessions. Focal bruising andâ¨numbness were present in up to 1.72% of treatment sessions. Twoâ¨cases of mild post-inflammatory hyperpigmentation over theâ¨forehead were noted within one month post treatment, both ofâ¨which have responded to topical bleaching agent. The treatmentsâ¨were well-tolerated with an average pain score of up to 6.85 out of COMBINED BASICâ¨SCIENCE, CUTANEOUSâ¨LASER SURGERY,â¨AND OTOLARYNGOLOGY 10. Conclusion: Transcutaneous high intensity focused ultrasoundâ¨appears to be safe and well-tolerated for non-invasive facial skinâ¨tightening in Asians. Adverse events are mild and transient. Noâ¨permanent or delayed side-effects were noted up to 6 months postâ¨treatment. 136 LASER GENERATED SHOCKWAVE FORâ¨CLEARING MEDICAL DEVICE BIOFILMSâ¨Yosef Krespi, Victor Kizhner, Paul Stoodley 133 St. Lukes-Roosevelt, New York, NYâ¨Allegheny General Hospital, Pittsburgh, PAâ¨Background: Biofilm has emerged as a new threat not amenableâ¨to most antibiotic treatments. Biofilms as opposed to planktonicâ¨bacteria develop exopolysaccaride matrix to facilitate adherenceâ¨to tissue or prosthetic surface forming a resistant shield. A new FRACTIONAL RADIOFREQUENCY TREATMENTâ¨SPARES SKIN STRUCTURES VITAL TO THEâ¨WOUND HEALING PROCESS Christopher Zachary, Bradley Renton, James Newman, Basil Hantash Published online in Wiley InterScienceâ¨(www.interscience.wiley.com). Â© 2009 Wiley-Liss, Inc.
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