www.renalandurologynews.com FEBRUARY 2010 Renal & Urology News 29
Gel Injection for VUR is Highly Effective Treatment
ENDOSCOPIC injection of non-animal- this approach by a single surgeon at undergo a VCUG, leaving an efﬁcacy after a single treatment, according to
stabilized hyaluronic acid/dextranomer the Baylor College of Medicine in population of 166 patients. In this a report in Urology (2009; published
gel (HA/Dx) is a highly effective treat- Houston. At least two after treat- group, the surgeon, Michael H. Hsieh, online ahead of print). After a second
ment for vesicoureteral reﬂux (VUR) in ment, patients were to return for a MD, PhD, who is now at Stanford treatment, the proportions increased
children and should be considered as a voiding cystourethrogram (VCUG) School of Medicine in Stanford, Calif., to 89.6% and 95.6%, respectively.
ﬁrst-line treatment option. assessment. treated 265 ureters (252 reﬂuxing and After a third treatment, the propor-
Researchers studied 178 children with After initial treatment, 12 patients 13 non-reﬂuxing). Reﬂux resolved in tions rose slightly to 90.2% and 96%.
VUR (mean age 4.2 years) treated with were lost to follow-up or had yet to 81.9% of subjects and 86.4% of ureters The procedures were associated with
HA/Dx gel became the ﬁrst material
approved by the FDA for endoscopic
injection in children with grade 2-4 VUR,
the authors noted. Endoscopic injection
of the gel usually is performed on an
outpatient basis. It requires no incision
and can be performed quickly. ■
Have a Role
LEAD EXPOSURE may be associated
with the initiation and development of
bladder cancer, according to a study
conducted in Poland.
A team led by Tomasz Golabek, MD,
now with Mercy University Hospital in