Jianing He DMD MDS enamel by benbenzhou

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									                         HE, JIANING, D.M.D., M.D.S, Ph.D.

                                  8900 Clear Sky Drive
                                    Plano, TX 75025
                                  jhe@bcd.tamhsc.edu
                                 (214) 828-8473 (work)
                                (972) 747-9886 (home)
                              (214) 828-8209 (facsimile)

Work Experience
October 2003 – present        Department of Endodontics
                              Baylor College of Dentistry
                              Dallas, TX
                               Assistant Professor
Education
July 2000 – October 2003      Department of Endodontology
                              University of Connecticut Health Center
                              School of Dental Medicine
                              Farmington, CT
                               Certificate in Endodontics

August 1997 – October 2003    Department of Biostructure and Function
                              Oral Biology Program
                              University of Connecticut Health Center
                              Farmington, CT
                               Ph.D.

September 1989 – June 1997    School of Dental Medicine
                              West China University of Medical Sciences
                              Chengdu, China
                               D.M.D., M.D.S.
Honors and Awards
2005                          Faculty Merit Award
                              Baylor College of Dentistry

                              Nominated for Teacher Of The Year
                              Baylor College of Dentistry

2003                          First place in graduate student oral research
                              presentation
                              American Association of Endodontics annual session

1996                          Bayer fellowship for excellence in dental student
                              research
                              Bayer AG, Germany

1995                          Outstanding student award
                              West China University of Medical Sciences




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Research Interests
    The roles of cycloxygenase-2 in periradicular inflammatory bone resorption
      Tissue response to dental procedures and materials in the pulp and periradicular region
      The roles of insulin-like growth factor I (IGF-1) in bone development and remodeling
      The mechanisms of the tissue-regenerative capacity of Emdogain
      Tissue compatibility of Mineral Trioxide Aggregate (MTA) and Portland Cement (PC)
Funded research activities
Current:
Texas A&M University Health Science Center Office of Vice President Research Development
Grant
Inflammatory cytokine expression and osteoclastogenesis in COX-2 deficient cells
Role: Principle investigator
Baylor College of Dentistry Faculty Intramural Grant FY04-5
Molecular mechanisms of tissue repair response to pulp capping
Role: Principle investigator
American Association of Endodontists Foundation Research Grant
The effect of COX-2 deficiency on inflammatory cytokine expression and osteoclast formation in
response to lipopolysaccharide and root canal obturation materials
Role: Principle investigator

Completed:
NIH/NIAMS
Pathogeneis and Prevention of Osteoporosis, subprojects 3 and 4
Role: Graduate student
NIH/NIDCR
Identification of Enamel Matrix Derivative (EMD) Regulated Genes
Role: Graduate Student
Teaching responsibilities
      Didactic, laboratory and clinical Endodontics for pre-doctoral dental students
      Mentoring and coordinating research activities for graduate endodontic students

Professional Membership and activities
    American Association of Endodontists
      American Dental Association
      American Society of Bone and Mineral Research
      The Endocrine Society
      Dallas Asian Dental Association
      Serve as a reviewer for the endodontic section of the journal Oral Surgery, Oral
       Medicine, Oral Pathology, Oral Radiology and Endodontics
      Served as a judge for graduate student research presentation during the 2005 American
       Association of Endodontics annual session



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Bibliography


1. He J., King Y., Jiang J., Safavi K. E., Spangberg L. S., Zhu Q. Enamel matrix derivative
   inhibits TNF--induced apoptosis in osteoblastic MC3T3-E1 cells. Oral Surg Oral Med Oral
   Pathol Oral Radiol Endod. 2005; 99 (6): 761-7

2. Lee A., He J., Zhu Q. Enamel matrix derivative stimulates the release of growth factors by
   human and mouse osteoblasts. J Endodon. 2005; 31 (3): OR 55 (Abstract)

3. He J., Jianing J., Safavi K. E., Spangberg L. S., Zhu Q. Direct contact between enamel
   matrix derivative (EMD) and osteoblasts is not required for EMD-induced cell proliferation.
   Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004; 98 (3): 370-375

4. He J., Safavi K. E., Spangberg L. S., Zhu Q. Enamel matrix derivative promotes osteoblast
   proliferation, differentiation, and the expression of osteoprotegerin. Oral Surg Oral Med
   Oral Pathol Oral Radiol Endod. 2004; 97 (2): 239-245


5. He J., Safaian G., Zhu Q. Analysis of gene expression in bone cells regulated by enamel
   matrix derivative using microarrays. AADR/IADR annual meeting, 2003 (Oral presentation)

6. Haglund R., He J., Jarvis J., Safavi K.E., Spangberg L.S., Zhu Q. Effects of Root-End Filling
   Materials on Fibroblasts and Macrophages in Vitro. Oral Surg Oral Med Oral Pathol Oral
   Radiol Endod. 2003; 95 (6): 739-45

7. Saidon Y., He J., Spangberg L.S. Cell and tissue reactions to mineral trioxide aggregate
   and Portland cement. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2003; 95(4): 483-9

8. He J., Jiang J., Lichtler A.C., Kream B.E. Effects of Insulin-like Growth Factor I (IGF-I)
   overexpression on primary osteoblasts in vitro. J Endodon 2002; 28 (3):243 OR33 (Abstract)

9. He J., Jiang J., Lichtler A.C., Kream B.E. Increased osteoblastic differentiation in primary
   murine osteoblasts transduced with an IGF-I/eGFP expressing retrovirus. J. Bone Miner.
   Res 2001; 16 (Suppl. 1): SU187. (Abstract)

10. He J., Stover M., Jiang J., Lichtler A.C., Kream B.E. Development of a bone-targeted
    bicistronic IGF-I/eGFP retroviral system for cell-based gene delivery. J. Bone Miner. Res
    2000; 15(Suppl. 1): S176. (Abstract)

11. He J., Ahamad M., Gronowicz G. The effect of TGF on mineralization in implant/osteoblast
    cultures. Graduate Student Research Day, University of Connecticut Health Center, 1998

12. He J., Cen Y., Mao X. A three-dimensional finite element stress analysis      of implant-
    supported prosthesis and its supporting tissue in the edentulous mandible. Part 6. The
    influence of superstructure in mandibular complete implant overdenture and its supporting
    tissue. Hua Xi Kou Qiang Yi Xue Za Zhi 1997 Feb;15(1):67-9. Chinese.

13. Cen Y., Mao X., He J. A three-dimensional finite element stress analysis of implant-
    supported prosthesis and its supporting tissue in the edentulous mandible. Part 5. The
    influence of implant type in complete implant overdenture and its supporting tissue
    Hua Xi Kou Qiang Yi Xue Za Zhi 1997 Feb;15(1):64-6. Chinese.



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