CURRICULUM VITAE collagen1

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					CURRICULUM VITAE
Niamh Nowlan
Email: nowlann@tcd.ie

Education
2007 Ph.D., Trinity Centre for Bioengineering, Trinity College Dublin, Ireland
     Thesis: “Mechanoregulation of Bone Formation: From Embryogenesis to Evolution”
     Supervisors: Dr. Paula Murphy (Zoology) & Prof. Patrick Prendergast (Trinity Centre for
     Bioengineering)
2006 P.Dip.Stat. (Postgraduate diploma in Statistics), Trinity College Dublin, Ireland.
     (Distinction)
2003 B.A. B.A.I., (Bachelor of Arts, Bachelor of Engineering), specialising in Computer
     Engineering, Trinity College Dublin, Ireland. Gold Medal and Distinction awarded.
1999 Leaving Certificate: 8 subjects at honours level; 5 A grades, 3 B grades.

Positions and Honours
Positions
2009 – present Postdoctoral Researcher, Centre for Genomic Regulation, Barcelona, Spain.
2009 (February – August)
               Visiting Scholar, Mechanical Engineering Department, Boston University,
               U.S.A.
2007 -2009     Postdoctoral research fellow, Zoology Department, Trinity College Dublin,
               Ireland.
2003           (July – September) Summer Research Student, Computer Science
               Department, Trinity College Dublin, Ireland.
2002           (June – September) Summer Intern, Le Centre Interuniversitaire de Calcul de
               Grenoble, France
2001           (June – September) Software Engineering Intern, IONA Technologies,
               Boston, U.S.A.

Honours & Awards
2008 - Fulbright Scholarship for six month research fellowship in Boston University, U.S.A.
      - Marie Curie Postdoctoral Fellowship for research to be carried out in the Centre for
         Genomic Regulation (Systems Biology Group) in Barcelona, Spain
2007 - Engineers Ireland Biomedical Research Medal 2007
      - Irish Research Council for Science Engineering and Technology (IRCSET)
         postdoctoral fellowship (2007-2009)
      - 1st Place, Royal Academy of Medicine in Ireland Student Competition
      - 2nd Place, American Society of Mechanical Engineering (ASME) PhD Student Paper
         Competition
      - 3rd Place, British Society of Developmental Biology Student Poster Competition
2006 - Royal Academy of Medicine in Ireland Bronze Medal
      - Honourable Mention, ASME PhD Student Poster Competition
      - Scholarship to attend the Jackson Lab 46th Annual Short Course in Medical and
         Experimental Mammalian Genetics (Maine, U.S.A.)
2003 - Gold Medal for degree examination results
      - IRCSET Embark Scholarship for postgraduate research
      - Maurice F. Fitzgerald Prize (advancement of knowledge in engineering)
      - MacNeill Prize (placed first in class in computer engineering degree)
      - Elected President of the Trinity St. Vincent de Paul Society (2003-2004)

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2002   - Stanford-Smith Prize (highest result), Collen Prize in Arts
       - Book prize (for obtaining first class honours in summer examinations)
       - „Diplôme de Langue‟, Alliance Française, Dublin
2001   - University of Dublin Scholarship (for academic excellence).
2000   - Book prize (for obtaining first class honours in summer examinations)

Professional Affiliations
Member: Institute of Engineers of Ireland (IEI), European Society of Biomechanics (ESB),
         Orthopaedic Research Society (ORS), British Society of Developmental Biology
         (BSDB).
Committee member: Orthopaedic Research Society (ORS) Membership Committee.

Publications and Presentations
Peer-Reviewed Journal Articles
   Nowlan, N.C., Prendergast P.J. and Murphy, P., “Identification of Mechanoregulatory
               Genes in vivo during Embryonic Bone Formation”, 2008. PLoS Computational
               Biology 4(12): e1000250 doi:10.1371/journal.pcbi.1000250.
   Nowlan, N.C., Murphy, P. and Prendergast P.J., “A Dynamic Pattern of Mechanical
               Stimulation Promotes Ossification in Avian Embryonic Long Bones”, 2008,
               Journal of Biomechanics, 41 (2), pp. 249-258.
   Roddy, K.A, Nowlan, N.C., Prendergast, P.J., Murphy, P., “3D representation of the
               developing chick knee joint: a novel approach relating multiple components”, in
               press, Journal of Anatomy.
   Foolen, J., van Donkelaar, C.C., Murphy, P., Nowlan, N.C., Huiskes, R., Ito, K., 2008.
               Collagen orientation in periosteum and perichondrium is aligned with
               preferential directions of tissue growth, J. Orthopaedic Research.
   Nowlan, N.C., Murphy, P., and Prendergast, P.J., “Mechanobiology of Embryonic Limb
               Development”, 2007. Annals of the New York Academy of Science, 1101, pp.
               389-411.
   Nowlan, N.C. and Prendergast P.J., “Evolution of Mechanoregulation of Bone Growth Will
               Lead to Non-optimal Bone Phenotypes”, 2005. Journal of Theoretical Biology,
               235 (3) pp. 408-418.

Book Chapters
   Prendergast, P.J., Nowlan, N.C., Lally, C., “Experiment and computation in
             mechanobiology, with new applications in cardiology and evolution”, 2005.
             Tissue Remodelling, Centre of Excellence for Applied Biomedical Modelling and
             Diagnostics (Editor: J. Piekarski), Warsaw, pp. 219-240.

Conference Presentations
   Oral Presentation: “Identifying Candidate Mechanoregulators of Skeletal Development”,
            2009 Summer Bioengineering Conference of the American Society of Mechanical
            Engineering, California, USA, 17th-21st June 2009.
   Oral Presentation: “Abnormal Mammalian Skeletogenesis in the Absence of Embryonic
            Muscle Contractions”, 55th Annual Meeting of the Orthopaedic Research Society,
            Las Vegas, Nevada, USA, 21-25th February, 2009.
   Oral presentation: “Patterning and differentiation of embryonic bone: the role of mechanical
            forces”, 10th International Conference on Limb Development and Regeneration,
            Madrid, Spain, 13th-16th August, 2008.
   Oral presentation: “Identification of Mechanoregulatory Genes in vivo during Embryonic
            Bone Formation”, 16th Congress of the European Society of Biomechanics,
            Lucerne, Switzerland, 6th-9th July 2008.


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   Oral presentation: “Mechanotransduction during Embryonic Bone Formation: A Role for
            Collagen X and Indian Hedgehog”, Northern Ireland Bioengineering Spring
            Meeting, Belfast, Ireland, 2nd April 2008.
   Oral Presentation: “Mechanoregulation of Embryonic Bone Formation: Using Finite
            Element Analysis to Identify Mechanosensitive Genes”, 54th Annual Meeting of
            the Orthopaedic Research Society, San Francisco, California, 2-5th March, 2008.
   Oral presentation: “Bone formation in the developing vertebrate limb: integrating
            morphology and gene expression patterns in a mechanical model 10th Irish
            Network of Developmental Biologists meeting, Cork, Ireland, 16th October 2007.
   Poster Presentation: “Correlation of computational and experimental data on mechanics in
            embryonic bone development”, Autumn Meeting of the British Society of
            Developmental Biology, Sheffield, U.K., 5–7th September, 2007.
   Oral Presentation: “Using FEA to Investigate Mechanoregulation of Embryonic Bone
            Formation”, ESB Workshop on Finite Element Modelling in Biomechanics and
            Mechanobiology, Dublin, Ireland, 26–28th August, 2007.
   Oral Presentation: “Mechanical Stimuli Resulting From Embryonic Muscle Contractions
            Promote Avian Periosteal Bone Collar Formation”, 2007 Summer Bioengineering
            Conference of the American Society of Mechanical Engineering, Keystone,
            Colorado, U.S.A., 21–24th June 2007.
   Oral presentation: “Finite element analyses of avian embryonic long bones indicate that
            mechanical forces due to embryonic muscle contractions commit cartilage cells to
            the osteogenic pathway”, Bioengineering in Ireland, Fermanagh, Ireland, 26–27th
            January 2007.
   Invited Oral Presentation: “The characterisation of mechanical stresses in the growing
            avian embryonic limb”, 5th World Congress of Biomechanics, Munich, Germany,
            29th July–4th August, 2006.
   Poster presentation: “The Calculation of Mechanical Stresses in the Growing Avian
            Embryonic Limb Using Optical Projection Tomography”, 2006 Summer
            Bioengineering Conference of the American Society of Mechanical Engineering,
            Amelia Island, Florida, U.S.A., 21–25th June, 2006.
   Oral presentation: "The Influence of Mechanical Forces in the Growing Embryonic Limb",
            52nd Annual Meeting of the Orthopaedic Research Society, Chicago, Illinois,
            U.S.A., 19–22nd March, 2006.
   Oral presentation: “The Calculation of Mechanical Stresses in the Growing Avian
            Embryonic Limb Using Optical Projection Tomography”, Bioengineering in
            Ireland, Galway, Ireland, 27–28th January 2006.
   Oral presentation: “The influence of mechanical forces on avian limb development”, 7th
            Meeting of the Irish Network of Developmental Biologists Winter Meeting, UCD,
            Dublin, Ireland, 15th December 2005.
   Oral presentation: “Computation of stresses in the growing embryonic chick limb”,
            International Conference on Computational Biomechanics, Lisbon, Portugal, 14–
            16th September 2005.
   Poster presentation: “Has Evolution led to the Optimal Skeleton”, (poster) Sir Bernard
            Crossland Symposium, Belfast, 6–7th April 2005.
   Oral presentation: “Optimality, Variation and Evolution: a Study using a Computational
            Model “, Bioengineering in Ireland, Dublin, Ireland, 28–29th January, 2005.
   Oral presentation: “A scheme for investigating the evolution of bone remodelling laws”,
            International Workshop for Numerical Models of Bone Adaptation and Repair,
            Ulm, Germany, 11–13th July 2004.
   Oral presentation: “A scheme for investigating the evolution of bone remodelling laws”,
            Bioengineering in Ireland, Limerick, Ireland, 30–31st January 2004.

Teaching Experience
2009      - Lecturer on MSc in Bioengineering “Biomechanics” module, October 2009.
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2008     - Invited speaker on Pre-Course of 16th Congress of the European Society of
            Biomechanics, Switzerland, 6th July 2008. Lecture title: Incorporating
            Mechanosensitive Gene Data into Mechanobiological Simulations”.
         - Lecturer on MSc in Bioengineering “Cell and Tissue” module, February 2008.
         - Guest lecturer on final year Engineering Biomechanics module.
         - Supervision of research project for MSc student in Trinity Centre for
            Bioengineering.
         - Supervision of undergraduate student researcher in Developmental Biology
            Laboratory.
         - Laboratory assistant for third year Developmental Biology.
2007        - Supervision of project student in Developmental Biology Laboratory, Zoology,
            Trinity College Dublin.
2006–2007 - Tutorial assistant for third year engineering tutorial “Engineering Mathematics”.
2005–2006 - Tutorial assistant for second year engineering tutorial “Thermodynamics and
            heat transfer”.
2003–2005 - Demonstrator for engineering laboratory; “Airfoil Aerodynamics”.

Course Participation
2006       - Techniques and Strategies in Molecular Medicine, run by the Dublin Molecular
              Medicine Centre (DMMC), 4, 5 & 7 December.
2005       - Jackson Lab 46th Annual Short Course in Medical and Experimental Mammalian
              Genetics, jointly run by The Jackson Laboratory and John Hopkins University, Bar
              Harbor, Maine, U.S.A., July 17-29.
2005       - “Laboratory Animal Science & Training (LAST) Ireland Training Course”
              (Qualification according to the FELASA recommendations for Category B & C).

Community Service
-           Active volunteer for the Sunshine Fund, part of the St. Vincent de Paul Society,
            which co-ordinates holidays for children from disadvantaged areas. Committee
            positions held include Vice-president (October 2007 – October 2008), Treasurer
            (January 2007 – October 2008), Head of volunteers‟ department (January –
            December 2006) and Ordinary member (April – December 2005).
-           President of Trinity College St. Vincent de Paul Society 2003-2004




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