Documents
Resources
Learning Center
Upload
Plans & pricing Sign in
Sign Out
Get this document free

Niacinamide Helps Lower Phosphorus

VIEWS: 14 PAGES: 2

A global leader in serving libraries of all types, ProQuest LLC (“ProQuest”) supports the breadth of the information community with innovative discovery solutions that power the business of books and the best in research experience. More than a content provider or aggregator, ProQuest is an information partner, creating indispensable research solutions that connect people and information. Through innovative, user-centered discovery technology, ProQuest offers billions of pages of global content that includes historical newspapers, dissertations, and uniquely relevant resources for researchers of any age and sophistication—including content not likely to be digitized by others.

More Info
									NIB1109.qxd                                10/27/09   1:27 PM         Page 2




      10 Renal & Urology News                                                          NOVEMBER 2009                                                                                                                www.renalandurologynews.com




                                                                                                                                                                                                       Please visit us at www.renalandurologynews.com




     News in Brief
       Severe LUTS, Big                                                                         CAC in Stage 3                                                      Warfarin May Raise Stroke
       Waists Linked                                                                            CKD Patients                                                        Risk in ESRD Patients
            study of 602 Korean men with
       A    lower urinary tract symptoms
       (LUTS) secondary to benign prosta-                                                       C     oronary artery calcification (CAC)
                                                                                                      is common among patients with                                 W      arfarin use in patients with both end-stage renal disease (ESRD) and
                                                                                                                                                                           atrial fibrillation are at increased risk for stroke, data suggest. It is not asso-
       tic hyperplasia found that those with                                                    stage 3 CKD, data show. Bryan R.                                    ciated with increased all-cause mortality or hospitalization.
       a waist circumference greater than                                                       Kestenbaum, MD, of the University of                                  Researchers followed 1,671 new ESRD patients with preexisting atrial fibril-
       90 cm (central obesity) had a 36%                                                        Washington in Seattle, and colleagues                               lation for an average of 1.6 years from the time they started dialysis. Compared
       increased risk of severe LUTS com-                                                       studied 562 adult patients with CKD                                 with nonuse, warfarin use was associated with a nearly twofold increased risk
       pared with men who had smaller                                                           (estimated glomerular filtration rate                               for a new stroke, investigators reported in the Journal of the American Society
       waists. In addition, in men with cen-                                                    [eGFR] of less than 60 mL/min/                                      of Nephrology (2009;20:2223-2233). Clopidogrel or aspirin use was not associ-
       tral obesity, prostate volume corre-                                                     1.73 m2) and without clinical car-                                  ated with the risk of a new stroke.
       lated positively with urgency and                                                        diovascular disease. The patients were                                The investigators concluded that “physicians should be cognizant of the pos-
       nocturia. Findings appear in the                                                         participants in the Multi-Ethnic Study                              sible risks associated with warfarin use for atrial fibrillation in patients with
       Asian Journal of Andrology (2009;                                                        of Atherosclerosis. Of the 562 subjects,                            ESRD, with careful evaluation of the risks and benefits of intervention at the
       published online ahead of print). n                                                      98% had stage 3 CKD at baseline                                     individual patient level.” n
                                                                                                (median eGFR of 55.4). The study
                                                                                                measured CAC at baseline and again
       Megestrol May                                                                            approximately 1.6 or 3.2 years later.
                                                                                                  At baseline, 370 subjects (66%) had
                                                                                                                                                                    Emergency Departments Found
       Improve Weight                                                                           CAC and 192 (34%) did not, accord-                                  To Underuse MET for Stones
                                                                                                ing to a report in Kidney International
             pilot study showed that mega-                                                      (2009;76:991-998). The prevalence                                         edical expulsive therapy (MET) for urinary stones in American emer-
       A     strol may help improve weight
       and the ability to exercise in dialy-
                                                                                                was 24% lower in African Americans
                                                                                                than in Caucasians after adjusting for
                                                                                                                                                                    M     gency departments (ED) is underused despite evidence of its safety
                                                                                                                                                                    and efficacy, investigators have concluded.
       sis patients, according to a report in                                                   numerous potential confounders. CAC                                   John M. Hollingsworth, MD, and colleagues at the University of Michigan in
       the Journal of Renal Nutrition (2009;                                                    developed in 39 (20%) who did not                                   Ann Arbor analyzed 2000-2006 data from the National Hospital Ambulatory
       published online ahead of print).                                                        have it at baseline, for an estimated                               Medical Care Survey. They determined MET use by the prescription for a cal-
         Investigators randomized nine el-                                                      incidence of 8.5% per year. The inci-              
								
To top