VIEWS: 27 PAGES: 7 CATEGORY: Medicine POSTED ON: 6/25/2010
[...] physicians need to be able to determine accurately that a patient is better off because of a specific treatment and whether an alternative treatment might provide the same or greater benefit. [...] with more research we may eventually know if, on average, a randomly selected combination presents an advantage over randomly selected monotherapy. [...] these studies were based on so-called enriched design. [...] the data can at best answer the question of whether to continue a combination if it has been effective.
Is Monotherapy as Good as Polypharmacy in Long-Term Treatment of Bipolar Diso... Martin Alda; Lakshmi N Yatham Canadian Journal o
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