The multicenter clinical trial of 224 postmenopausal women - led by D. Lee Alekel, professor of nutrition and interim associate director of the Nutrition and Wellness Research Center (NWRC) at ISU and supported by the National Institute of Arthritis, Musculoskeletal and Skin Diseases, one of the research institutes of the National Institutes of Health (NIH) - was the longest ever conducted on the effects of soy isoflavones on bone mineral density (BMD).
inform April 2010, Vol. 21 (4) 225 Briefs Comprehensive metabolomic analy- Health & Nutrition ses led by Shawn Ritchie of Phenom- enome Discoveries Inc. in Saskatoon, Saskatchewan, Canada, revealed sig- nificantly reduced levels of C28 –C36 carbon-containing hydroxylated poly- unsaturated ultra-long-chain fatty acids in all three independent cohorts of colorectal cancer (CRC) patient samples relative to controls. “These metabolites are easily measurable in serum and a decrease in their con- centration appears to be highly sen- sitive and specific for the presence of CRC, regardless of ethnic or geo- graphic background,” the authors write in BMC Medicine (doi: 10.1186/1741- 7015-8-13). “The measurement of these metabolites may represent an additional tool for the early detec- tion and screening of CRC,” they con- clude. The complete article is available at http://tinyurl.com/yex6lqp. nnn Another recent study suggests a daily dose of 1.8 grams of docosahexaenoic acid (DHA) “has potential to substan- tially increase survival in metastatic Little effect of soy of soy isoflavones on bone mineral density (BMD). It compared the effects of ingest- breast cancer patients treated with isoflavones on ing daily either 80-mg or 120-mg soy iso- flavone tablets, compared to placebo tablets, bone loss chemotherapy,” according to research- on BMD and other health outcomes. ers led by Philippe Bougnoux of the ISU NWRC researchers collaborated French Institut National de la Santé et A previous six-month study by Iowa with research physiologist Marta D. Van de la Recherche Médicale (INSERM) State University (ISU; Ames, Iowa, USA) Loan and her colleagues at the US Depart- in Tours. The new study, if supported researchers had indicated that consuming ment of Agriculture Agricultural Research by additional research, suggests that modest amounts of soy protein, rich in iso- Service’s Western Human Nutrition DHA may help improve survival by flavones, lessened lumbar spine bone loss Research Cent
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