Little effect of soy isoflavones on bone loss by ProQuest


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									                                                                                               inform April 2010, Vol. 21 (4) 225

  Comprehensive metabolomic analy-
                                              Health & Nutrition
  ses led by Shawn Ritchie of Phenom-
  enome Discoveries Inc. in Saskatoon,
  Saskatchewan, Canada, revealed sig-
  nificantly reduced levels of C28 –C36
  carbon-containing hydroxylated poly-
  unsaturated ultra-long-chain fatty acids
  in all three independent cohorts of
  colorectal cancer (CRC) patient
  samples relative to controls. “These
  metabolites are easily measurable in
  serum and a decrease in their con-
  centration appears to be highly sen-
  sitive and specific for the presence
  of CRC, regardless of ethnic or geo-
  graphic background,” the authors write
  in BMC Medicine (doi: 10.1186/1741-
  7015-8-13). “The measurement of
  these metabolites may represent an
  additional tool for the early detec-
  tion and screening of CRC,” they con-
  clude. The complete article is available
  Another recent study suggests a daily
  dose of 1.8 grams of docosahexaenoic
  acid (DHA) “has potential to substan-
  tially increase survival in metastatic
                                               Little effect of soy                           of soy isoflavones on bone mineral density
                                                                                              (BMD). It compared the effects of ingest-
  breast cancer patients treated with          isoflavones on                                 ing daily either 80-mg or 120-mg soy iso-
                                                                                              flavone tablets, compared to placebo tablets,
                                               bone loss
  chemotherapy,” according to research-
                                                                                              on BMD and other health outcomes.
  ers led by Philippe Bougnoux of the
                                                                                                   ISU NWRC researchers collaborated
  French Institut National de la Santé et      A previous six-month study by Iowa             with research physiologist Marta D. Van
  de la Recherche Médicale (INSERM)            State University (ISU; Ames, Iowa, USA)        Loan and her colleagues at the US Depart-
  in Tours. The new study, if supported        researchers had indicated that consuming       ment of Agriculture Agricultural Research
  by additional research, suggests that        modest amounts of soy protein, rich in iso-    Service’s Western Human Nutrition
  DHA may help improve survival by             flavones, lessened lumbar spine bone loss      Research Cent
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