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									000A22_MPR_0410.qxp         3/25/2010       12:09 PM      Page 1

                               Highlights of recent developments
   Zyrtec Liquid Gels available Bisphosphonate warning         CitraNatal B-Calm
                                    The FDA has announced, that
                                    at this point, the data that have
                                    been reviewed have not shown
                                    a clear connection between
                                    bisphosphonate use and a risk
                                    of atypical subtrochanteric
                                    femur fractures. The FDA will
                                    continue to review new infor-
                                    mation as it becomes available
                                    and will provide an update
   Zyrtec Liquid Gels (cetirizine when complete. Healthcare              Mission Pharmacal has
   HCl liquid gels, from McNeil professionals should continue            expanded its CitraNatal prod-
   Consumer Healthcare) have        to follow drug label recom-          uct line with the addition of
   been made available for the      mendations when prescribing          CitraNatal B-Calm prenatal
   treatment of allergic rhinitis   oral bisphosphonates. Patients       vitamins. CitraNatal B-Calm
   in patients ≥6 years of age.     should not stop taking their         contains the CitraNatal formula
     Zyrtec Liquid Gels are         medication unless told to do         plus 25mg of vitamin B6 in the
   available in a 10mg dosage       so by their healthcare provider.     multivitamin and two 25mg
   strength. The Zyrtec product     Oral bisphosphonates are com-        vitamin B6 supplements to be
   line is already available in     monly prescribed to prevent or       taken at eight-hour intervals.
   tablet, chew tablet, and syrup   treat osteoporosis in postmeno-      Studies have suggested that
   formulations.                    pausal women. Medications            vitamin B6 supplementation
     For more information           in this class include Actonel        may be beneficial in minimiz-
   call (800) 343-7805.             (risedronate tablets, from Procter   ing pregnancy-related nausea
                                    & Gamble), Boniva (ibandro-          and vomiting.
   Exalgo for managing pain         nate tablets and injection, from       See Section 14A.
   Exalgo (hydromorphone HCl Roche), Fosamax (alendronate
   extended-release tablets, from tablets and oral solution, from        Kapidex name change
   Covidien) has been approved      Merck), and Reclast (zoledronic      Kapidex (dexlansoprazole
   to manage moderate to severe acid solution for IV infusion,           delayed-release capsules, from
   pain in opioid-tolerant patients from Novartis).                      Takeda) will now be marketed
   requiring continuous, around-      For more information visit         under a new product trade
   the-clock opioid analgesia for           name, Dexilant, due to reports
   an extended period of time.      h/SafetyInformation/SafetyAle        of dispensing errors between it
   Exalgo utilizes the OROS         rtsforHumanMedicalProducts/          and Casodex (bicaluta
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