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www.renalandurologynews.com MAY 2010 Renal & Urology News 9 News in Brief Please visit us at www.renalandurologynews.com for the latest news updates from the ﬁelds of urology and nephrology Short Takes ED Signals Higher Mortality Diabetes Increases Post-op Death Risk of mice were genetically programmed to develop prostate cancer. The tumors And Cardiovascular Risk Patients with diabetes who undergo that developed in the walnut-fed mice cancer surgery are approximately 50% more likely to die shortly after were about half the size of those in the other mice, and grew 30% more slowly. E rectile dysfunction (ED) is a strong predictor of all-cause mortality and the composite of cardiovascular death, heart attack, stroke, and heart failure in men with cardiovascular disease (CVD), according to the results of a worldwide the operation than non-diabetics. This study of 1,519 men with ED and CVD. Compared with men who had CVD only, additional risk was present across a Donor Gene Variants Predict men with both CVD and ED were twice as likely to die from all causes and 1.6 range of cancers and surgical treat- Kidney Graft Success times more likely to suffer the composite of cardiovascular death, heart attack, ments for the disease, according to a Particular variations of the CAV1 gene stroke, and heart-failure hospitalization. Speciﬁcally, men with the dual diagnoses were twice as likely to die from CVD or to have a heart attack. They also were meta-analysis of 15 published studies. in a kidney donor may determine the 20% more likely to be hospitalized for heart failure and 10% more likely to The heightened mortality risk may be success of a kidney transplant. A new have a stroke. The ﬁndings, published in Circulation (2010;121:1439-1446), also at least partially attributable to the analysis uncovered signiﬁcant differ- revealed that ACE inhibitors, angiotensin receptor blockers, or a combination of higher infection and cardiovascular ences in graft survival according to the two had no inﬂuence on the development or course of ED, but could reduce disease rates associated with diabe- donor genotypes of CAV1, which has cardiovascular events in high-risk patients, according to researchers. tes. Findings appear in Diabetes Care a role in tissue ﬁbrosis and vascular (2010;33:931-939) proliferation. In 785 kidney donors Walnuts Slow Prostate and their recipients in Birmingham, England, allograft failure rates were HCV-Infected Kidneys May Tumor Growth Mice that consumed approximately 14 38.6% for donor genotype AA, 22.3% for donor genotype CC, and 22.2% Help HCV-Infected Recipients shelled walnuts per day for two months for donor genotype AC over a median exhibited signiﬁcantly smaller, slower- growing prostate tumors after 18 follow-up of 81 months, according to a report in the Journal of the American A lthough kidneys infected with hepatitis C virus (HCV) were 2.
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