www.renalandurologynews.com MAY 2010 Renal & Urology News 9
News in Brief
Please visit us at www.renalandurologynews.com for the latest news updates from the fields of urology and nephrology
Short Takes ED Signals Higher Mortality
Diabetes Increases
Post-op Death Risk
of mice were genetically programmed
to develop prostate cancer. The tumors
And Cardiovascular Risk
Patients with diabetes who undergo that developed in the walnut-fed mice
cancer surgery are approximately
50% more likely to die shortly after
were about half the size of those in the
other mice, and grew 30% more slowly.
E rectile dysfunction (ED) is a strong predictor of all-cause mortality and the
composite of cardiovascular death, heart attack, stroke, and heart failure in
men with cardiovascular disease (CVD), according to the results of a worldwide
the operation than non-diabetics. This study of 1,519 men with ED and CVD. Compared with men who had CVD only,
additional risk was present across a Donor Gene Variants Predict men with both CVD and ED were twice as likely to die from all causes and 1.6
range of cancers and surgical treat- Kidney Graft Success times more likely to suffer the composite of cardiovascular death, heart attack,
ments for the disease, according to a Particular variations of the CAV1 gene
stroke, and heart-failure hospitalization. Specifically, men with the dual diagnoses
were twice as likely to die from CVD or to have a heart attack. They also were
meta-analysis of 15 published studies. in a kidney donor may determine the
20% more likely to be hospitalized for heart failure and 10% more likely to
The heightened mortality risk may be success of a kidney transplant. A new
have a stroke. The findings, published in Circulation (2010;121:1439-1446), also
at least partially attributable to the analysis uncovered significant differ- revealed that ACE inhibitors, angiotensin receptor blockers, or a combination of
higher infection and cardiovascular ences in graft survival according to the two had no influence on the development or course of ED, but could reduce
disease rates associated with diabe- donor genotypes of CAV1, which has cardiovascular events in high-risk patients, according to researchers.
tes. Findings appear in Diabetes Care a role in tissue fibrosis and vascular
(2010;33:931-939) proliferation. In 785 kidney donors
Walnuts Slow Prostate
and their recipients in Birmingham,
England, allograft failure rates were
HCV-Infected Kidneys May
Tumor Growth
Mice that consumed approximately 14
38.6% for donor genotype AA, 22.3%
for donor genotype CC, and 22.2%
Help HCV-Infected Recipients
shelled walnuts per day for two months for donor genotype AC over a median
exhibited significantly smaller, slower-
growing prostate tumors after 18
follow-up of 81 months, according to
a report in the Journal of the American
A lthough kidneys infected with hepatitis C virus (HCV) were 2.