Summary Statement Under the general direction of the Director of the Molecular Instrumentation Center (MIC), provide management and all aspects of technical support for a wide range of mass spectrometry instrumentation and experimentation for research in chemistry, biochemistry, medicine, materials science, physics and engineering. Additionally, provide technical support for the design and execution of appropriate experimental protocols to enable collaborative research involving the application of modern mass spectrometric methods. Type of Supervision Received/Exercised The Associate Director of Mass Spectrometry is expected to work very independently with only general guidance about MIC goals and policies from the Director of the Molecular Instrumentation Center. TYPE OF PERCENTAGE FUNCTION OF CORE FUNCTIONS/DUTIES TIME E ( Essential) or M (Marginal) BACKGROUND: The UCLA Molecular Instrumentation Center (MIC) is a state-of-the- art campus-wide facility created to enable the use of modern instrumentation in molecular characterizations. The MIC Mass Spectrometry Laboratory provides a wide range of sample characterization techniques for UCLA researchers that include: electron impact (EI), chemical (CI), matrix assisted laser desorption (MALDI), electrospray ionization (ESI), and atmospheric pressure chemical ionization (APCI). Analyzers currently available include magnetic sector, time of flight, quadrupole, ion trap and ion cyclotron resonance analyzers, and several tandem combinations of mass analyzers. Faculty and researchers require technical support for widely diverse research activities on the synthesis, characterization, testing and other studies that would benefit by the application of modern mass spectrometry to the problem. The wide range of research problems and diverse backgrounds of the user community requires careful attention to issues of high throughput, efficient training, and implementation of systems for productive shared usage. 40% A. Manage and participate in the operation, maintenance, troubleshooting, E and repair of equipment in the mass spectrometry laboratory. Arrange for outside vendors or campus shops to provide maintenance and upgrades, as required. 1) Carry out mass spectrometry measurements on samples provided by researchers. 2) Maintain the hardware and software of existing and future instruments to be acquired. 3) Plan and provide required regular maintenance. 4) Troubleshoot and repair instrument failures. B. Design and apply experimental methods for the application of modern mass spectrometry to a large variety of chemical, biochemical, 25% biomedical, and materials problems. E 1) Consult with the individual researchers and when needed with the faculty supervisors to ascertain the nature of the problems to be solved. 2) Implement new methods to approach the problem based on publications in the published literature. 3) Test new methods with known compounds to be assured of reliable results. C. Manage training and train research users and students with various, 10% appropriate backgrounds on the correct procedures and methods of E operation of equipment and to process the data as effectively as possible. 1) Write, for publication, concise directions for operation, data analysis, and experimental details for all mass spectrometers in the laboratory. 2) Develop and continuously update appropriate in-laboratory instructions to clarify operational procedures. 3) Provide information and advice to potential users of the facility. 4) Train and supervise appropriate students and other researchers in the use of the equipment and interpretation of the results. D. Provide laboratory management support. 20% E 1) Maintain database of user information and instrument reservation and usage. 2) Submit recharge information on a monthly basis for processing by business office personnel. Maintain, improve, and streamline recharge systems including computer programs. 3) Project and determine recharge rates to recover consumable costs and to regularly recommend to the MIC director updates of rates to reflect changes in consumable prices. 4) Maintain the Mass Spectrometry Laboratory web site for information that is beneficial to users of the facility. 5) Work with the MIC director and faculty to support the design, specification, procurement and modification of space. 6) Implement and improve laboratory security measures and user access authorization. 7) Lead compliance with all State and UCLA mandated safety and environmental requirements. E. Take the lead in actively improving the available instrumentation and 5% E ancillary equipment required for effective application of mass spectrometry to research problems at UCLA. 1) Participate in the preparation of grant proposals to obtain funding for additional equipment. 2) Prepare reports to granting agencies for equipment obtained on grants. 3) Manage all aspects of installation of new equipment. DUTY IMPORTANCE COMPETENCIES (SKAs, Behaviors, Attributes) REFERENCE required, preferred, or may be trained Demonstrated skill in modern mass spectrometry. A,B,C,E Required Demonstrated broad knowledge of research and development in organic A,B,C,E Required chemistry, biochemistry, ion chemistry, and chemical analysis to support a diverse array of research and instrumentation. Commitment to the implementation and utilization of modern C, E Required instrumentation into undergraduate and graduate instruction. Ability to teach experimental details to researchers with a broad range of A,B,C Required scientific backgrounds. Broad knowledge with hands-on experience in laboratory instrumentation. A,C Required Technical and scientific ability for operation, instruction, routine maintenance and minor repair. Demonstrated skill in troubleshooting hardware and software problems A,C,D Required encountered with instrumentation. Skill in prioritizing tasks in an environment where a large variety of All Required research is conducted using shared equipment. Ability to work simultaneously and productively on several projects in a All Required demanding environment. Supervisory skills to organize materials, information and people in a All Required systematic way to optimize efficiency and minimize duplication of effort. Excellent interpersonal skills to interact with graduate and undergraduate All Required students, staff, faculty, and visitors. Excellent verbal skills and ability to speak either on a one-to-one basis or All Required in a group using appropriate vocabulary and grammar to obtain and clearly convey information, and explain complex scientific and technical issues. Excellent skill in writing concise, logical, grammatically correct All Required documents, e.g. instruction manuals, descriptions of the facilities and technical capabilities of the equipment. Problem identification and resolution skills to organize work flow to All Required accomplish established objectives. Ability to work independently or as a team, follow through on All Required assignments with minimal direction and identify potentially better methods of operation. Ability to work with individuals with a wide diversity of backgrounds. All Required Ability to teach, demonstrate and guide others in the preparation, quality B,C Required control, and setup of laboratory experiments and provide technical and scientific expertise. Knowledge of safe handling and disposal of hazardous chemicals and safe A,B,C,D May be trained laboratory practices. Knowledge of current state, federal, OSHA and UCLA regulations as they apply to the laboratories. Working knowledge of inventory and material management procedures. D May be trained
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