CANCER NUTRITION
Dr. Martin Chasen Medical Oncologist/ Palliative Care Physician
Clinical Director McGill Cancer Nutrition and
Rehabilitation Program
The McGill University Nutrition-Rehabilitation Programme
www.mcgill.ca/cnr
McGill Cancer Nutrition – Rehabilitation Program
Cancer rehabilitation is a process that assists the patient to obtain optimal physical, social, nutritional, psychological and vocational functioning within the limits created by the disease and its treatment
McGill Cancer Nutrition – Rehabilitation Program (CNRP)
Organizational Structure
McGill Department of Oncology Division of Palliative Medicine Departments of Medicine and Oncology MUHC
Origin 2003 with clinics at the Sir Mortimer B Davis-Jewish General Hospital and Department of Medicine MUHC 2006 Cancer Rehabilitation Program RVH
Role of the Dietitian
complete a thorough nutrition assessment design a nutrition care plan tailored to the patient’s needs provide counseling and information on optimizing food intake provide counseling on symptom control such as nausea, vomiting, diarrhea, etc ensure adequate food intake to optimize function and quality of life
American Society of Parenteral and Enteral Nutrition recommends that all patients undergo nutritional screening as a component of their initial assessment
Nutritional Status is important:
Predicts the risk associated with treatment Predicts response to treatment Predicts survival and Quality of Life
Cancer Cachexia
Progressive weight loss Early satiety Generalized weakness Decreased function Progressive wasting
Nutritional Screening
Early recognition = Screening
Height Weight Weight change Diagnosis, stage Co-morbidities
1. 2. 3. 4. 5.
Nutritional Assessment
Registered Dietitian
1. 2. 3. 4. 5.
Medical history Dietary history Physical examination Antropometric measurements Laboratory data
To be effective
In routine clinical practice Patients screened at initial visit Early education
PG-SGA
Weight
Present, one month ago, six months ago Weight in last 2 weeks: decreased, increased unchanged Unchanged, more than usual, less than usual
Food Intake
Symptoms
No problems eating, no appetite, taste changes, nausea, vomiting, diarrhea, constipation, mouth sores, dry mouth, swallowing problems, smells bothersome, feel full quickly, pain Normal with no limitations, not normal but able to be up and about with fairly normal activities, not feeling up to most things, able to do little activity , pretty much bedridden
Activities and Function
Use of Patient Generated Subjective Global Assessment Tool
Dietary Counseling improves patient outcomes. A prospective, randomized, controlled trial in colorectal cancer patients undergoing radiotherapy. Paula Ravasco, Isabel Monteiro-Grillo, Pedro Marques Vidal et al.
JCO 23:1431-1438 March 1 2005
111 colorectal patients 45 stage I/II 66 Stage III/IV
37 – dietary counseling on regular foods 37 – protein supplements (2 cans/day) 37 – ad libitum intake
RAVASCO
Evaluation
Nutritional Intake (diet history)
24 hour food recall questionnaire
Anthropometric Data PGSGA QoL (EORTC – QLQ – C30
At end of RT
Group 1 – Energy intake increase of 555kcal/d (398 – 758) p = 0.002 Group 2 – Energy intake increase of 296 kcal/d (286 – 401) p = 0.04 Group 3 – Energy intake decreased - 285kcal/d (201 – 398) p < 0.1
Group 1 > Group 2 (p = 0.001)
Baseline
15 malnourished in Group 1 14 malnourished in Group 2 13 malnourished in Group 3 At 3 month Additional nutritional degeneration in G 2 and G3 relative to G1 (p < 0.001)
Quality of Life
At 3 months: G1 patients maintained or improved QoL (p < 0.02) G2 patients maintained or worsened QoL (p < 0.03) G3 patients deteriorated (p< 0.004)
CANCER REHAB TEAM
Physician Nurse Psychologist Physiotherapist Occupational Therapist Dietician Nurse Educator Medical Secretary
January - October 2006
136 new patient referrals Age Range: 18-84 yrs 71 male 65 female Diagnoses: Hepato-biliary -- 21 Breast –20 Gastro/Esophageal –28 Pancreatic – 10 Colorectal – 12 Lung –12 Gynecological- 10 Hematological – 15 Other – 9
Gastric Pacesetter and EGG Waves
3
EGG Procedure
Visipace Electrogastrogram Analyzer
1. Baseline (10 min) 2. Water load 3. Test (30 min)
3
EGG Summary Report
3
Studies Carried out at MUHC
Age Distribution (19-82 yrs)
2
Total number of Patients (n= 24)
10 14
male female
16
6
< 30 30 - 60 > 60
3
Studies Carried out at MUHC (cont’d)
Patients' diagnoses
8 7 6 5 4 3 2 1 0 7 6 6 5
GI (esophageal, pancreatic, gastric, colon)
lung
breast + ovarian+ endometrial
others (brain, leukemia, myeloma, multiple mets unknown primary)
3
100%
Studies Carried out at MUHC
10%
20%
30%
40%
50%
60%
70%
80%
90%
0%
87% 80% 73% 73% 60% 60% 53% 53% 47% 47% 47% 40% 40% 40% 40% 40% 33%
Dyspepsia Symptoms of the Patients
Fu ll fe Fr el eq in In g St ue ab af om nt ilit te y bu ac rm to rp h ea f in di in sc g ls ish pr om no be fo rm lch rt, al w in -s ith g ize ou d tp m ai ea n, ls af St te om rm ac ea ha ls ch e St Bl be om oa fo t in ac re g h m di ea st ls en or tio w n he St om n hu ac ng St ha ry om ch e ac at ha ni ch gh e t af Re te rm flu Bu x ea du rn ls rin in g g fe th el e in da g y Bu in th rp e in ch g Na wi es us th t Na ea bi tte us wh rf ea en lu id be w fo ak re e up m ea in ls th e Bu m or rn ni in Re ng g flu fe x el at in g ni in gh th t e st Na om us ac ea h af te rm ea ls Re tc hi ng
20%
3
EGG Result
The result of the EGG test
10 9 8 7 6 5 4 3 2 1 0 9 7
2 1
3
2
bradygastria
mixed dysrhythmiatending to bradygastria
normal
tachygastria
mixed dysrhythmiatending to tachygastria
mixed dysrthythmianonspecific
3
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