Pharmacology
Drugs Used to Treat Disorders of
Eyes & Ears
Topics
• Glaucoma
• Mydriasis Induction
• Ophthalmic anesthetics
Glaucoma
• Degenerative disease Beta Blockers
of optic nerve timolol (Timoptic®),
• Frequently associated betaxolol (Betoptic®)
with intraocular Cholinergic
pressure (IOP)
pilocarpine (Isopto
• Therapy aimed at Carpine®)
IOP Causes miosis
Diagnostic Mydriasis &
Cycloplegia
• Anticholinergics • Adrenergic Agonists
– Atropine solutions – Phenylephrine (AK-
• Atropisol® Dilate®)
– Scopolamine solutins
• Isopto Hyoscine®
• Local anesthetic
• Tetracaine (Pontocaine®)
• Ester, not amide
• chemically unrelated to lidocaine
Drugs Affecting The Ear
• Antibiotics • Swimmer’s Ear
– chloramphenicol – isopropyl alcohol
• Chloromycetin Otic® • AuroDri® Ear Drops
– gentamicin sulfate otic – boric acid/isopropyl
• Aurocaine 2®
• Garamycin®
• Ear wax break up • Ototoxic side effects
– carbamide peroxide • aspirin
• NSAIDS
• Auro Ear Drops®
• erythromycin
– glycerin • vancomycin
• Ear Wax Removal® • vurosemide (Lasix®)