; Researchers Demonstrate a New Model for Drug Discovery with a Fluorescent Anesthetic
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Researchers Demonstrate a New Model for Drug Discovery with a Fluorescent Anesthetic


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     about other adverse events and near misses.                               initiated. “Though not surprising, this under-reporting was disap-
        Through August 2007, 15,524 surgical patients were reported            pointing,” the authors wrote. “During the study period, interventions
     including 957 (6.2 percent) adverse events and 34 (0.2 percent)           aimed at increasing reporting had little effect.” A presentation from
     anonymous reports. “The automated pattern recognition system              the department chair regarding what constitutes an adverse event and
     helped identify four event patterns from morbidity and mortality          the importance of tracking complications produced an initial spike in
     reports and three patterns from anonymous/near-miss reporting,” the       reporting that was short-lived.
     authors wrote. “After multidisciplinary meetings and expert reviews,
     the patterns were addressed with educational initiatives, correction of   Conclusion
     systems issues and/or intensive quality monitoring.” For instance,        The authors concluded that an online event tracking system “should
     recurring errors in chest tube placements and nurse-to-physician          be incorporated into all surgery departments irrespective of whether
     communications were detected and managed.                                 the department is associated with a residency program; however, this
        The events entered into the online system also were compared           is just one component of what should be a larger quality improve-
     with hospital databases to assess the completeness of reporting. Only     ment effort,” the authors concluded. “An online event tracking system
     27.2 percent (264 of 970) of readmissions and 41.6 percent (89 of         is a feasible, promising and potentially powerful initiative to improve
     214) of inpatient deaths were reported into the system; there was no      surgical safety in the United States.”I
     change in monthly adverse reporting rate when the online system was       Source: JAMA/Archives Journal

     Researchers Demonstrate a New Model for Drug
     Discovery with a Fluorescent Anesthetic
       n use for more than 150 years, general         action, a missing component that has             and the Austin Lamont Professor of

     I anesthetics are one of medicine’s greatest
       advances and yet there is still much to be
     learned about them. A collaboration of
                                                      hindered anesthetic research.
                                                          Researchers confirmed the compound as
                                                      anesthetic after testing it successfully in
                                                                                                       Anesthesiology and Critical Care at Penn’s
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