VIEWS: 116 PAGES: 3 CATEGORY: Medicine POSTED ON: 6/13/2010
One advantage that PP monobiisters have compared with aluminium/PVC types is that they do not curve during late-stage production, making it easier to sbt them into cartons or other packets. This is because they are made of a single material, and do not suffer from differential expansion between the aluminium and PVC. The thermoforming and sealing films each have advantages compared with aluminium and PVC.
solid dosage www.pharma-mag.com BListeR paCks poLypRopyLene is Best Peter Forsmark, Technical Director, Recipharm (stockholm, sweden) explains why polypropylene blister packs are better than aluminium and PvC blisters now that the technical barriers to manufacturing them have been overcome. lister packs made entirely of PP (polypropylene) have many advantages compared with aluminium and PVC blisters, the most common type on the market. Among these advantages are lower weight and production costs, higher performance and less environmental impact throughout the production process. Polypropylene monoblisters typically consist of two plastic films with different properties, such as Etimex Purelay Pharm and Purelay Lid films (Figure 1). The ‘Pharm’ film is a PP thermoforming film that is similar to the PVC or PvdC (polyvinylidene chloride)-coated PVC films used in an aluminium/PVC blister, whereas the PP push- Figure 1: Monoblister formation, comparing Al/PVC with PP blister packs. through lidding film seals the blister and serves the same purpose as the aluminium. Examples of when PP monoblisters have replaced PVC/ PP MOnOBLIsTeRs DO nOT CuRve DuRIng LATe- aluminium blisters are Reliv and Alvedon, two paracetamol products widely used in Sweden. sTAge PRODuCTIOn, MAkIng IT eAsIeR TO One advantage that PP monoblisters have compared with aluminium/PVC types is that sLOT THeM InTO CARTOns OR OTHeR PACkeTs. they do not curve during late-stage production, making it easier to slot them into cartons or other PP thermoforming films are also better than in 1995, Recipharm (then Recip) has been packets. This is because they are made of a PVC in other respects. They are less dense, strongly committed to being an environmental single material, and do not suffer from differential lighter and more transparent, and the stiffness trendsetter in the pharmaceutical industry. expansion between the aluminium and PVC. of PP is better suited to pushing tablets from Recip was one of the first pharmaceutical The thermoforming and sealing films each have the packaging. In addition, PP thermoforming companies to be certified according to advantages compared with aluminium and PVC. films produced by heating and quenching the ISO 14001 in 1997 and, in 2001, Recipharm PP thermoforming films are more cost-effective polypropylene have excellent thermoforming undertook a product lifecycle analysis to assess than PVC films coated with PVdC sealant wrap behaviour and barrier properties. The PP
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