Two pharmaceutical marketing tools used for patient acquisition in the physician's office are patient starter kits with money-off coupon offers and physical product samples. Both have their advantages, but there are specific situations where the benefits of coupons may outweigh those of samples, particularly if you extend their value by tying them into other patient and physician relationship-marketing programs. Shire launched Vyvanse in June 2007, with the goal of making this product the US ADHD market leader within three years, and surpassing the success that the company had developed in the category with Adderall XR. The success of the Vyvanse launch illustrates a variety of benefits of utilizing free trial offers as part of a new patient starter kit. Using the combo card instead of samples allowed Vyvanse marketing to provide patients with valuable ADHD disease state and product information, and also opt in for compliance and persistence programs.