Identifying and Competing for NIH Grant Funding

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					Identifying and Competing for
      NIH Grant Funding
            September 23, 2009
    Texas A&M University–Corpus Christi

      Office of Proposal Development
           Texas A&M University
     Texas A&M Health Science Center
                  John Ivy
              johnivy@tamu.edu
                         Presenter
    John Ivy, AB PhD, Research Development
     Officer
          Undergrad and graduate degrees in biology
          Postdoctoral experience in yeast molecular biology
          Ten years as scientist, group leader with small
           biotech company supported in large part by federal
           SBIR grants
          Ten years experience as research scientist and
           lecturer, Dept. of Biology, TAMU
          Three years experience in current position with TAMU
           and TAM-Health Science Center


                                 Texas A&M University
23 September 2009           Office of Proposal Development    2
             Texas A&M University
        Office of Proposal Development
   Unit of Office of Research and Graduate Studies
   Supports Texas A&M faculty in the development
    and writing of research and educational proposals:
       Center-level initiatives
       Multi-investigator Program Project grants
       Multidisciplinary and multi-institutional research teams
       Junior faculty research
       Diversity in the research enterprise

                                Texas A&M University
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                    OPD Member List
    Jean Ann Bowman, PhD                                 jbowman@tamu.edu
      Physical Geography/Hydrology, earth, ecological, environmental
    Mike Cronan, PE, BS (Civil/Structures), BA, MFA
      Center-level proposals, research and educational partnerships, new
        proposal and training initiatives                 mikecronan@tamu.edu
    Lucy Deckard, BS, MS (Materials)                        l-deckard@tamu.edu
      New faculty initiative, fellowships, engineering/physical
        science proposals, equipment, and instrumentation
    John Ivy, PhD (Molecular Biology)                          johnivy@tamu.edu
      NIH biomedical and biological science initiatives
    Phyllis McBride, PhD (English)                         p-mcbride@tamu.edu
      Proposal writing training, biomedical, editing
    Libby Pasciak                                               libbyp@tamu.edu
      Scheduling, workshop management, project coordination
    Robyn Pearson, BA, MA (Anthropology)                    rlpearson@tamu.edu
      Social sciences and humanities proposals, editing and rewriting

                                     Texas A&M University
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           Office of Proposal Development
          OPD-WEB http://opd.tamu.edu/
         For an electronic version of this presentation
         Funding opportunities
         Junior faculty support
         Proposal development resources
         Grant writing seminars and workshops
         Craft of Grant Writing Workbook
         Agency Toolkits
         PI perspectives on competitive proposals

                               Texas A&M University
23 September 2009         Office of Proposal Development   5
                    For more information

     For    an electronic version of this
         presentation and background
         materials
            Go to http://opd.tamu.edu/
            Click on ―Seminar Materials‖ then
             ―Seminars by Date‖
            Click on today’s date




                               Texas A&M University
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                                 Topics
              Finding Research Funding Opportunities
              Overview of the National Institutes of
               Health
                   Mission
                   Funding mechanisms
                   Reading the FOA
                   Assessing the opportunity and your
                    competitiveness
              Preparing NIH proposals
                   Content and Strategy
              Review process for NIH Proposals
              Resources
                                     Texas A&M University
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                If you don’t write grants,
                    you won’t get any
          Target     the proposal at the
              intersection where:
                research dollars are available
                your research interests lie
                available time to write a
                 competitive proposal
                              Texas A&M University
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        Your Research Interests will
          define funding sources
                   Your research interests should align
                    with the Mission of the Agency
                            Biology
                            Biomedicine
                            Health disparities
                            Behavior
                            Biochemistry
                            Computational science
                            Interdisciplinary studies

                                    Texas A&M University
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 Know the category of funding in
    which you are interested
                       Research
                       Training
                       Fellowship
                       Student retention
                       Student recruitment
                       Diversity
                       Curriculum
                       Loan reimbursement
                                 Texas A&M University
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           Funding Sources for
           Biomedical Research
      National Institutes of Health $29 bill.
      National Science Foundation $6 bill.
      Dept. of Health & Human Services
      Department of Defense
      Foundations
      Environmental Protection Agency
      US Department of Agriculture
      National Aeronautics & Space Admin.


                         Texas A&M University
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          Where do you find the RFPs?
                    (Who ya gonna call?)
    Federal agency web sites
    Discussions with Agency and
     Foundation Representatives
    University posted listings
    Foundation web sites
    Professional societies
    Network with colleagues
    Funding sources cited in
     literature acknowledgements
    Google searches
    E-mail listserves (last but not
     least)



                                    Texas A&M University
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                    Grants.gov
      The Grants.gov web portal serves as a
      single point of access for all federal
      agency grant announcements. New
      funding announcements from federal
      agency are posted to this site daily, and
      a range of other features allow
      subscribing to email funding alerts,
      linking to agency web sites, and
      searching for funding among agencies.

                           Texas A&M University
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                    http://www.grants.gov/




                                Texas A&M University
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                    Grants.gov Search




                              Texas A&M University
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             Vaccine Keyword Results




                          Texas A&M University
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 Find NIH Funding Opportunities

         NIH Office of Extramural Research
               http://grants1.nih.gov/grants/oer.htm
               http://grants1.nih.gov/grants/guide/index.html
                       Search by keyword
                       Browse by Requests for Applications (RFAs)
                       Browse by Program Announcements (PAs)
                       Automatic funding alerts

         Institutes and Centers (IC) homepages
               Listed at http://www.nih.gov/icd
                       Go to IC homepage
                       Browse or search their “Research Funding” or "Extramural
                        Funding” section

                                            Texas A&M University
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                         Texas A&M University
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Example – Sequencing Technology




                         Texas A&M University
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Example – Sequencing Technology




                         Texas A&M University
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  Staying
 Informed
  on NIH
   FOAs




                         Texas A&M University
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Identifying NIH Solicitations by IC

   Steps for identify funding opportunities
    within an Institute or Center (IC)
     Identify appropriate IC from mission statements
     Go to their homepage http://www.nih.gov/icd
     Go to their ―Research Funding‖ or Extramural
      Funding‖ section
     Search or browse
     Sign up for Listserv or RSS feed notification


                          Texas A&M University
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          OPD-Web Funding Opportunities




                         Texas A&M University
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 TAM-HSC Office of Research & Graduate Studies




                         Texas A&M University
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 http://foundationcenter.org/pnd/rfp/




                         Texas A&M University
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    Example
      of a
    Google
     Search




                         Texas A&M University
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    Life Science Funding Source Listings
    Grants.gov                                                                         http://www.grants.gov

    National Institues of Health
          Office of Extramural Research                                  http://grants.nih.gov/grants/OER.htm
          Individual Institutes and Centers
          Sign up for email listserves or RSS feeds

    National Science Foundation                                                            http://www.nsf.gov/
          Find Funding                                                             http://www.nsf.gov/funding/
          Funded Research                                                   http://www.nsf.gov/awardsearch/

    GrantsNet sponsored by AAAS and HHMI
                                                              http://sciencecareers.sciencemag.org/funding

    Congressionally Directed Medical Research Programs
                                                                    http://cdmrp.army.mil/funding/default.htm

    Philanthropy News Digest RFP listings                      http://foundationcenter.org/pnd/rfp/
          American Cancer Society                 http://www.cancer.org/docroot/RES/RES_0.asp
          American Heart Association http://www.americanheart.org/presenter.jhtml?identifier=9713
          Cancer Research Institute                   http://www.cancerresearch.org/criprogs.html
          Life Sciences Research Foundation                        http://www.lsrf.org/geninfo.htm
          National Multiple Sclerosis Society                   http://www.nationalmssociety.org/
                                              Texas A&M University
23 September 2009                        Office of Proposal Development                                      27
            Identifying funding opportunities
                       SUMMARY

   Develop search
    protocols to fit
    research interests
   Know relevant
    agencies
   Learn grant cycles



                            Texas A&M University
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      NIH Organization and culture
                    NIH Mission
    NIH is the steward of medical and
     behavioral research for the Nation. Its
     mission is
       science in pursuit of fundamental knowledge
        about the nature and behavior of living
        systems and
       the application of that knowledge to extend
        healthy life and reduce the burdens of illness
        and disability.

                            Texas A&M University
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         National Institutes of Health
      NIH is a basic research agency
      Each Institute has its own mission
      Each Institute has its own budget
      Each Institute has its own activities
      Each Institute has its own ways of doing things

       When you’re planning to submit a grant,
              check with a Program Officer
       to determine alignment of your research
       questions with their IC's mission, their specific
       policies, and the IC's priorities.
                             Texas A&M University
23 September 2009       Office of Proposal Development     30
               FY 2008 Operating Plan
                                 $29.46 Billion

                               Training
               Research Mgmt
                                  3%
                & Support 4%
                                                                   Research Project
         All Other 5%                                                Grants 52%
                                                                      $15.165
Other Research 6%


Research Centers
      10%


          R&D Contracts                                             84% awarded to >325,000
              10%                                                    extramural researchers
                                Intramural
                                 Research
                                    10%

                                       Texas A&M University
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        NIH Organizational Structure
                                                        Office of the Director


                                                                                National Institute                              National Institute
                          National Institute        National Institute
 National Institute                                                              of Arthritis and        National Cancer         of Child Health
                          on Alcohol Abuse           of Allergy and
     on Aging                                                                   Musculoskeletal              Institute             and Human
                           and Alcoholism         Infectious Diseases
                                                                               and Skin Diseases                                  Development



National Institute on     National Institute       National Institute
                           of Dental and                                                                National Institute
Deafness and Other                                 of Diabetes and             National Institute                                 National Eye
                                                                                                        of Environmental
 Communication              Craniofacial            Digestive and               on Drug Abuse                                       Institute
                              Research                                                                   Health Sciences
     Disorders                                     Kidney Diseases



                                                                                                        National Institute
 National Institute        National Heart,         National Human
                                                                               National Institute       of Neurological         National Institute
    of General            Lung, and Blood         Genome Research
                                                                               of Mental Health          Disorders and        of Nursing Research
 Medical Sciences             Institute                Institute
                                                                                                             Stroke




National Center on        National Center                                                                                      National Institute
                        for Complementary                  Fogarty              National Center
 Minority Health                                                                                          National Library      of Biomedical
                                                        International            for Research
    and Health            and Alternative                                                                   of Medicine          Imaging and
                             Medicine                      Center                 Resources
    Disparities                                                                                                                Bioengineering



                                            NIH
                                                                          Center                   Center                    No funding
                                                                     for Information            for Scientific

      23 September 2009
                                      Clinical Center            Texas A&M University
                                                                       Technology
                                                            Office of Proposal Development
                                                                                                   Review                    authority
                                                                                                                                     32
            NIH Funding Mechanisms

           Three         principal types
                     Training—T&F
                     Career Development — K
                       K99/R00,     K01, K08, etc.
                     Research     Project Grant — R
                       R01,   R03, R21



                                      Texas A&M University
23 September 2009                Office of Proposal Development   33
                    NIH Training Awards
       Individual Training awards – for predoctoral (F31),
        postdoctoral (F32), or senior fellowships (F33)
       Limited to US citizens or legal aliens

                                   Ruth L. Kirschstein
                        National Research Service Awards (NRSA)
           Institutional Research Training Grants (T32)
           Short-Term Institutional Research Training Grants (T35)
           Individual Predoctoral Awards For M.D./Ph.D. Fellowships (F30)
           Individual Predoctoral Fellowship Minority Students (F31)
           Individual Predoctoral Fellowship Students w/ Disabilities (F31)

           Individual Predoctoral Fellowship (F31)
           Individual Postdoctoral Fellowships (F32)
           Senior Fellowships (F33)

                                           Texas A&M University
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             NIH Career Development
                    K Awards
     Directed at retraining, professional career
      development, or recognition of career success
     Typically requires 75% research effort
     K Kiosk
      http://grants1.nih.gov/training/careerdevelopmentawards.htm

     Career Award Wizard
      Helps you select the right career award
      http://grants.nih.gov/training/kwizard/index.htm

     Participation may be restricted to certain
      Institutes and Centers

                                    Texas A&M University
23 September 2009              Office of Proposal Development       35
                      NIH Career Awards
    Some directed at retraining, professional career
     development, and recognition of career success
    Participation in many may be restricted to certain ICs
          K01 Mentored Research Scientist
                Provides mentored career development in a new research area
                3-5 yr, 75% effort
          K02 Independent Scientist
                Provides support for newly independent scientists (see IC
                 provisions) who can demonstrate the need for a period of intensive
                 research focus as a means of enhancing their research careers.
                3-5 yr, 75% effort
          K99/R00 NIH Pathway to Independence
                2 years mentored postdoctoral research + 3 years independent
                 research in tenure track position (or equivalent)
                Must have fewer than 5 yr postdoc experience
                Open to US and non-US citizens
                                          Texas A&M University
23 September 2009                    Office of Proposal Development                   36
          Research Grants for Independent
                    Scientists
    R01 – Large Research Grant
          4-5 years, $250,000+/yr
    R03 – Small Grant
          2 year max, $50,000/yr max
    R21 – Exploratory Research Grant
          High Risk – High Reward
          Transformational
          2 years, $275,000 total
    R15 – Academic Research Enhancement Award
     (AREA)
          Primarily undergrad institutions
          Institute must have received <$3mill/yr in NIH funding

                                 Texas A&M University
23 September 2009           Office of Proposal Development      37
                 Unsolicited vs. Solicited
    NIH makes a distinction between unsolicited
     versus solicited proposals
          Unsolicited (investigator-initiated) proposals (82%)
                   Submit in response to a Parent Announcement
                   The parent announcement is simply a vehicle for you to
                    submit an investigator-initiated application for a given
                    mechanism in any area that meets the NIH mission.

          Solicited (agency-initiated) proposals (18%)
                   Program Announcements (PA)
                         New research programs and updates to ongoing programs
                          (renewable)
                   Request for Applications/Proposals (RFA/RFP)
                         One time request to fulfill specific agency research objective or
                          need

                                              Texas A&M University
23 September 2009                        Office of Proposal Development                   38
                Unsolicited vs. Solicited


         Agency initiated →

         Agency initiated →

Investigator initiated →




                             Texas A&M University
23 September 2009       Office of Proposal Development   39
                Parent Announcements




                           Texas A&M University
23 September 2009     Office of Proposal Development   40
        Parent Announcements (more)




                         Texas A&M University
23 September 2009   Office of Proposal Development   41
                    Reading an NIH FOA
            NIH Funding Opportunity Announcements
             have two main parts
            Part I. Overview Information
                   Issuing Organization
                   Participating Organizations
                   Components of Participating Organization
                   Title
                   Announcement Type
                   Program Announcement Number
                   Key Dates
                   Executive Summary

                                      Texas A&M University
23 September 2009                Office of Proposal Development   42
                    Contents of an NIH PA
                    Part II. Full Text of Announcement
  Section I. Funding Opportunity Description                       Section V. Application Review Information
    1. Research Objectives                                             1. Criteria
                                                                       2. Review and Selection Process
  Section II. Award Information                                          A. Additional Review Criteria
    1. Mechanism(s) of Support                                           B. Additional Review Considerations
    2. Funds Available                                                   C. Sharing Research Data
                                                                         D. Sharing Research Resources
  Section III. Eligibility Information                                 3. Anticipated Announcement and Award
    1. Eligible Applicants                                             Dates
       A. Eligible Institutions
       B. Eligible Individuals                                           Section VI. Award Administration
    2. Cost Sharing or Matching                                          Information
    3. Other - Special Eligibility Criteria                              1. Award Notices
                                                                         2. Administrative and National Policy
  Section IV. Application and Submission                                 Requirements
  Information                                                            3. Reporting
    1. Address to Request Application Information
    2. Content and Form of Application                                   Section VII. Agency Contact(s)
  Submission                                                             1. Scientific/Research Contact(s)
    3. Submission Dates and Times                                        2. Peer Review Contact(s)
        A. Submission, Review and Anticipated                            3. Financial/ Grants Management
  Start Dates                                                            Contact(s)
           1. Letter of Intent
        B. Sending an Application to the NIH                             Section VIII. Other Information - Required
        C. Application Processing                                        Federal Citations
    4. Intergovernmental Review
    5. Funding Restrictions
    6. Other Submission Requirements
                                                   Texas A&M University
23 September 2009                             Office of Proposal Development                                     43
                    Program Solicitation
     From the PA or RFA –
          Determine supporting ICs
          Identify mechanism (R, T, U, etc.)
          Determine eligibility
          Identify review criteria
     Learn essential information to develop and
      write a competitive proposal that is fully
      responsive to the agency’s objectives and
      review criteria.
     Use the RFP as an organizational template to
      develop the structure, order, and detail of the
      proposal narrative and to address all review
      criteria.
                                 Texas A&M University
23 September 2009           Office of Proposal Development   44
    Assess the Competition:
 Know what was recently funded
       Learning about recently funded research in
        your area helps you understand what an
        agency is looking for in the review process
             Search on-line databases of funded projects
             Review abstracts of funded proposals on agency
              web sites
             Talk to the principal investigators of funded
              proposals in your area
             Obtain copies of funded proposals
                Ask the PI



                                  Texas A&M University
23 September 2009            Office of Proposal Development    45
              RePORT Expenditures and
                     Results
 http://projectreporter.nih.gov/reporter.cfm
 RePORT is replacing CRISP (Computer
     Retrieval of Information on Scientific Projects)
    A searchable database of federally funded
     biomedical research
       What similar projects have been funded?
       Has someone already been funded to pursue
        my idea?
       Who are my competitors?
       Who are potential collaborators?

                            Texas A&M University
23 September 2009      Office of Proposal Development   46
                         Texas A&M University
23 September 2009   Office of Proposal Development   47
                    Preparing Proposals
     All NIH proposals use either the
      electronic form SF424 or the
      paper PHS398.
     Step 1:
      Download the Instructions and
      Forms via the NIH OER website
           http://grants2.nih.gov/grants/fundi
            ng/424/
           http://grants1.nih.gov/grants/fundi
            ng/phs398/phs398.html
     Step 2:
      READ THE INSTRUCTIONS



                                         Texas A&M University
23 September 2009                   Office of Proposal Development   48
  Common Elements of NIH R01
            Cover page/face sheet
            Description: Project Summary (Abstract) & Relevance
            Performance site, key personnel
            Table of contents
            Budget page(s)
            Budget justification
            Biosketch of PI, biosketch of all other major/key personnel
            Resources
            Research Plan (Items A-D)
            Other Information under Research Plan (Items E-J)
                   References cited, human or animal research subjects,
                    inclusion of minorities/children in clinical studies, data sharing
                    plans, etc.
            Appendix items
            Checklist
                                            Texas A&M University
23 September 2009                      Office of Proposal Development                    49
                      Before you begin . . .
    Make sure you have identified the following:
          Goal
                   Indicates the purpose for the project as a whole
                   Should be aligned with the agency’s mission
          Aims
                   Indicate the purpose for each specific part of your project
                   Should be aligned with your overall goal
                   Should be specific and measurable
          Rationale
                   Indicates why you want to achieve your purpose
                   Should be clear and logical
          Expected outcomes
                   Indicate what will change as a result of your research
                    (e.g., behavior, performance, process, produce)
                   Should include both immediate and long-term outcomes

                                           Texas A&M University
23 September 2009                     Office of Proposal Development              50
  Speak with the Program Officer
         – early and often
                                                      Do   your homework first

                                                      Make   an appointment

                                                      Listen   to the response

                                                      Request    clarification

                                                      Follow   up




                         Texas A&M University
23 September 2009   Office of Proposal Development                           51
 Make your proposal competitive
    Title, Abstract, and Specific Aims are key
       May be all reviewers read
       Must excite and grab the attention
 Reviewers will assume errors in language
  and usage will translate into errors in the
  science
 Don’t be overly ambitious in what you
  propose, but convey credibility and
  capacity to perform
                            Texas A&M University
23 September 2009      Office of Proposal Development   52
                                       Title
         Used by agency administrators to route
          your proposal to the appropriate reviewers
         Should provide an accurate representation
          of your proposed project
         Should generate interest in and enthusiasm
          for your proposed project
         Should conform to agency requirements
                   Program name
                   Number of characters (NIH: 81 incl. spaces)


                                       Texas A&M University
23 September 2009                 Office of Proposal Development   53
         Project Summary (Abstract)
       One of the most critical sections
       Consider writing the Abstract after you've written your
        Research Plan
       Use the same elements of the Specific Aims in the
        same order
       Include
             Brief introduction to the topic
             Gap in knowledge or critical need
             Broad, long-term goals
             Specific Aims
             Describe research design and methods
             Summarize the Significance of the project
             Avoid summary of past accomplishments
             Avoid use of the first person


                                     Texas A&M University
23 September 2009               Office of Proposal Development    54
                    Project Relevance
       The second component of the Project
        Summary/Abstract (i.e., ―Description‖) is
        Relevance.
       Corresponds to "Project Narrative" in SF424
        forms
       Using no more than two or three sentences,
        describe the relevance of this research to
        public health.
       Be succinct and use plain language that can
        be understood by a general, lay audience.


                              Texas A&M University
23 September 2009        Office of Proposal Development   55
                           Research Plan
            Introduction (Resubmissions only)
           A) Specific Aims
                    Long-range goals
                    Hypothesis
                    Aims and methods
           B) Background & Significance
           C) Preliminary Studies / Progress Report
           D) Research Design and Methods
                    Structure based on Specific Aims

                                      Texas A&M University
23 September 2009                Office of Proposal Development   56
                         Specific Aims
              Provide a framework for the reviewer
              State a long-range goal of your research
               program
              Identify the gap in knowledge or critical need
              State a project goal
              State a central hypothesis that your
               experiments will address
              Provide a rationale for your approach
              State specific, measurable Specific Aims
              Discuss expected outcomes
              Do not be overly ambitious!

                                    Texas A&M University
23 September 2009              Office of Proposal Development   57
              General organization of the
                   Specific Aims the
                           Introduction to
                                                problem.
          General                     Identification of need
                                      or gap in knowledge.
                                       Long term research
                                        goal and specific
                                          project goal
                                       Central hypothesis
                                            Specific Aims




          Specific             Project outcomes & benefits

                            Texas A&M University
23 September 2009      Office of Proposal Development          58
             Specific Aims – Attributes
      Critically important
      Must provide a conceptual overview
      Must outline the project goals, objectives (aims), and
       expected outcomes
      Must be clearly written
      Must grab the reviewer’s attention
      Must generate enthusiasm for the project
      Must be able to stand alone
      Often Title, Abstract and Specific Aims may be the
       only three parts that all reviewers will have an
       opportunity to read
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               Your Central Hypothesis
    The foundation of your application – the conceptual
     underpinning on which the entire structure rests.
    Generally applications should ask questions that prove
     or disprove a hypothesis rather than use a method to
     search for a problem or simply collect information.
    Choose an important, testable, focused hypothesis that
     increases understanding of biologic processes,
     diseases, treatments, or preventions and is based on
     previous research.
    State your hypothesis in both the Specific Aims section
     and the Abstract.


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                      Specific Aims
       Don't be overly ambitious
             2-5 aims for an R01
       Avoid descriptive aims
             No fishing expeditions; no look-and-see!
       Use brief, concise, informative,
        conceptual statements (headline style)



                                Texas A&M University
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                    Writing for Reviewers

 Reviewers often have 8 or 10 proposals to
  read
 Use white space, underlining, bold, bullets,
  figures, flowcharts to make main points
  easy to find
 Put main idea of sections and paragraphs
  up front


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                    Writing for Reviewers
    Sell your proposal to a good scientist but not
     an expert
    Some review panels may not have an expert in
     your field, or panels may be blended for
     multidisciplinary initiatives
    Agencies & reviewers fund compelling, exciting
     research
    Proposals are not journal articles – proposals
     must be user-friendly and offer a narrative that
     tells a story that is memorable to reviewers

                               Texas A&M University
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           Albert Einstein on Grant Writing
    "If you can't explain something
     simply, you don't understand it
     well enough."
    "Most of the fundamental ideas
     of science are essentially
     simple, and may, as a rule, be
     expressed in language
     comprehensible to everyone."
    "Any fool can make things
     bigger, more complex, and
     more violent. It takes a touch
     of genius—and a lot of
     courage—to move in the
     opposite direction."
                                Texas A&M University
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       Must Convince Reviewers…
     Your proposed research should be
      funded
         It’s important and supports the agency
          mission and program goals
         It’s exciting
         It has a good chance of succeeding
         You are the person who should conduct the
          proposed research
                You are knowledgeable and well-qualified
                You have the support and resources required

                                   Texas A&M University
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     Charles Mingus on Grant Writing

    "Making the simple
    complicated is
    commonplace;
    making the
    complicated simple,
    awesomely simple,
    that's creativity."

                         Texas A&M University
23 September 2009   Office of Proposal Development   66
        Understand the NIH Review
                 Process
Center for Scientific Review

                                         Scientific Review Group
       FUNDING                            or IC Review Branch
       DECISION

                                                IC Advisory Council

                    Institute Director

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        Understand the NIH Review
                 Process
        Center for Scientific Review
              http://cms.csr.nih.gov/
                       News and Reports
                       Peer Review Meetings
                       Resources for Applicants
        Assigns proposals to Study Section
        Describes the peer review process
        Provides a list of study section rosters
        Offers a video of a mock review session
              NIH Grant Review Process Video

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        Understand the NIH Review
                 Process
        Review is merit-based
        All applications assigned to three reviewers
        Streamlining (Triage): Reviewers identify
         those they believe in the bottom 50%
        Study Section discusses the top ~50% of
         applications
        Priority score (10-90) and percentile ranking
         are sent to PI
        Scientific Review Officer prepares a written
         summary of your proposal based on written
         critiques and Study Section discussion
        Summary statement is sent to PI
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       Know your NIH Review Criteria
      Overall Impact
            The likelihood for the project to exert a sustained, powerful
             influence on the research field(s) involved
      Core Criteria
            Significance
                   Ability of the project to improve health or advance the field
            Investigator(s)
                   Education, training, relevant experience
            Innovation
                   Originality of research
            Approach
                   Feasibility of methods and appropriateness of budget
            Environment
                   Suitability of facilities and institution support

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          Revisions & Resubmission
   Three strikes and ―you’re out‖

   Read the reviewer’s comments
         Take a break
   Re-read the reviewer’s
    comments
         Don’t take them personally
   Read the reviewer’s comments,
    AGAIN
   Call the program officer for
    feedback
   Evaluate if you should resubmit
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                    Persevere Intelligently
       Plan on rejection
             Funding rates typically 20% or lower
             Even the best researchers are declined more than
              they are funded
             Agencies expect you to revise and resubmit
       Ways to respond to a declined proposal
             Get discouraged and stop applying
             Disregard reviewers’ comments and resubmit
             Learn from reviewers’ comments and revise
              intelligently
       Pursuing grants is like honing in on a target

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                      Web Resources
      National Institutes of Health http://www.nih.gov/
            Grant Application Basics
             http://grants.nih.gov/grants/grant_basics.htm
            All About Grants Tutorial
             http://www.niaid.nih.gov/ncn/grants/default.htm
            New Investigator Portal
             http://www.niaid.nih.gov/ncn/grants/new/portal.htm
            Annotated R01 Research Plan and Summary
             Statement
             http://www.niaid.nih.gov/ncn/grants/app/
            Mock Peer Review Video
             http://www.csr.nih.gov/Video/Video.asp
            CRISP funded biomedical research
             http://crisp.cit.nih.gov/

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                      Web Resources
      Office of Proposal Development, TAMU                            http://opd.tamu.edu/
            Funding Opportunities               http://opd.tamu.edu/funding-opportunities
            Resources for Junior Faculty        http://opd.tamu.edu/resources-for-junior-faculty

            Agency Toolkits
      National Science Foundation                                      http://www.nsf.gov/
            Find Funding                                          http://www.nsf.gov/funding/
            Funded Research                            http://www.nsf.gov/awardsearch/
      Grants.gov                                                    http://www.grants.gov
      GrantsNet sponsored by AAAS and HHMI
                                  http://sciencecareers.sciencemag.org/funding
      Congressionally Directed Medical Research Programs
                                         http://cdmrp.army.mil/funding/default.htm
      Philanthropy News Digest RFP listings
                                                    http://foundationcenter.org/pnd/rfp/

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                    Questions?



                           Texas A&M University
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