Schedule for the Frontiers at the Chemistry and Biology Interface Symposium in the Mid-Atlantic Region Saturday April 12, 2008, Department of Chemistry & Biochemistry, University of Maryland at College Park
Morning Sessions
8:30 - 9:00 am Coffee/snack, set up morning session posters (M1 – M36) 9:00 - 9:20 Welcome and introduction
Lecture Session Chair, Craig Townsend, Johns Hopkins University 9:20 - 9:50 9:50 - 10:10 10:10 -10:30 Unleashing the Power of Semi-Synthesis: The Discovery of Torisel, Jerry Skotnicki, Chemical Sciences Interface, Wyeth Research. Deconstruction of Iterative Multidomainal Polyketide Synthase Function, Anna L Vagstad, Jason M. Crawford, Jonathan R. Scheerer and Craig Townsend, Department of Chemistry, The Johns Hopkins University. Coupled Binding and Unfolding: Small Molecule Binding to c-Myc+, Steven J. Metallo, Ariele Viacava Follis, Dalia Hammoudeh, Huabo Wang, Edward V. Prochownik, Department of Chemistry, Georgetown University.
10:30 - 11:20 Morning poster session (M1 – M36) Lecture Session Chair, John Koh, University of Delaware 11:20 - 11:40 Inherent Antibacterial Activity of a Peptide-Based β-Hairpin Hydrogel, Daphne A. Salick,1 Juliana K. Kretsinger,1 Lisa A. Haines-Butterick,1 Darrin J. Pochan,2 Joel P. Schneider,1 1Department of Chemistry and Biochemistry, and 2 Department of Material Science and Engineering, University of Delaware. 11:40 - 12:00 c-di-GMP, a Novel Signaling Molecule in Bacteria, Herman Sintim, Irene Kiburu and Andrew Shurer, Department of Chemistry and Biochemistry, University of Maryland, College Park. 12:00 - 12:20 Application of Carbohydrate Microarray Technology to Cancer Research, Jeff Gildersleeve, Laboratory of Medicinal Chemistry, National Cancer Institute, NIH. 12:20 - 1:30 pm box lunch provided in Atrium (take down morning posters by 1 pm, put up afternoon posters A1- A35)
Afternoon Sessions
Lecture Session Chair, Phil Cole, Johns Hopkins Medical School 1:30 - 2:00 Dynamic Visualization of Signaling Activities in Living Cells, Jin Zhang, Michael Allen, Bharath Ananthanarayanan, Lisa DiPilato, Matthew Fosbrink, Xinxin Gao, Robert Newman, and Qiang Ni, Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD. The NIH Chemical Genomics Center, Craig J. Thomas, NIH Chemical Genomics Center, National Human Genome Research Institute, National Institutes of Health. Fungal Rtt109 is an Unexpected Structural Homolog of Human p300/CBP, Marc A. Holbert,3 Yong Tang,1 Katrina Meeth,1 Eva Jiang,1 Ronen Marmorstein,1,2 and Philip A. Cole3, 1Program in Gene Expression and Regulation, The Wistar Institute, 3601 Spruce Street, Philadelphia, PA 19104; 2Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104; 3Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine Afternoon poster session (A1 – A35) and coffee break/snacks
2:00 - 2:20 2:20 - 2:40
2:40 - 3:30
Lecture Session Chair, Jim Fishbein, University of Maryland, Baltimore County 3:30 - 3:50 Design of Protein Kinase-Inducible Domains, Neal J. Zondlo, Shalini Balakrishnan, Feng Gao, and Susan Carr Zondlo, Department of Chemistry and Biochemistry, University of Delaware. Inhibition of HCV as an Opportunistic Co-Infection of HIV by Ring-Expanded Nucleoside Analogues Containing the Imidazo[4,5-e][1,3]di-azepine Ring System, Ramachandra Hosmane1, Peng Zhang,1 Ning Zhang,1 Hongyi Cai,1 Andrea Baier,2 Peter Borowski,2 Brent E. Korba,3 Venkata Yedavalli,4 Kuan-Teh Jeang,4 and Yves Pommier,5 1Laboratory for Drug Design and Synthesis, Department of Chemistry & Biochemistry, University of Maryland, Baltimore County; 2Catholic University of Lublin John Paul II, Al. Krasnicka, Lublin, Poland; 3Department of Microbiology & Immunology, School of Medicine, Georgetown University Medical Center; 4Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious; 5Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute D-(+)-iso-Methanocarbathymidine, a High Affinity Substrate for HSV-tk, Victor Marquez,1 M. J. Comin,1 C. B. Vu,2 P. L. Boyer,2 C. Liao,1 S. H. Hughes,2 1 Laboratory of Medicinal Chemistry, Center for Cancer Research, National Cancer Institute at Frederick; 2HIV Drug Resistance Program, Center for Cancer Research, National Cancer Institute at Frederick
3:50 - 4:10
4:10 - 4:30
Sponsored by Department of Chemistry & Biochemistry, University of Maryland College Park College of Chemical & Life Sciences, University of Maryland College Park Department of Chemistry & Biochemistry University of Maryland, Baltimore County Department of Chemistry & Biochemistry, The University of Delaware Department of Chemistry, Johns Hopkins University Department of Pharmacology & Molecular Sciences, Johns Hopkins School of Medicine The Washington NMR Group