NYU CENTER FOR HEALTH INFORMATICS &
OFFICIAL LAUNCH 11-6-2009
The mission of the Center for Health Informatics and
Bioinformatics (CHIBI) is to catalyze transformative
changes in biomedicine through breakthrough
computational methodological research, best practices
services, state of the art infrastructure, and cutting-edge
Welcome & program outline
Opening remarks by Dean Robert I. Grossman, MD.
Opening remarks by Vice Dean Vivian S. Lee, MD, PhD, MBA.
Highlights from Year #1 of CHIBI & Upcoming
Research & researcher highlights:
Yuval Kluger Ph.D.
Alexander Alekseyenko Ph.D.
Stuart Brown Ph.D.
Alexander Statnikov Ph.D.
Conclusion & social gathering
OPENING REMARKS BY DEAN & CEO
ROBERT I. GROSSMAN, MD.
OPENING REMARKS BY VICE DEAN
VIVIAN S. LEE, MD, PHD, MBA.
WHAT IS HEALTH INFORMATICS AND
BIOINFORMATICS (“AKA BIOMEDICAL INFORMATICS”)?
The science that invents and studies computing methods for
discovery, storage, retrieval, and optimal use of biological and
medical information and knowledge
Brief History of Biomedical Informatics as a Discipline
The field of Biomedical informatics is surprisingly old.
1949: In Germany, the first professional organization for informatics, currently known as the Deutsche
Gesellschaft fur Medizinische Dokumentation, Informatik und Statistik, was founded by Gustav Wagner.
1960: The first appearance of medical informatics (broadly defined to include “biomedical informatics” as well
as “health informatics”) as a term ("Informatique Medicale") occurred in France.
1960s: Specialized university departments and training programs were created as early as the 1960s in
France, Germany, Belgium, and The Netherlands.
1970s: Dedicated medical informatics research units also appeared in Poland, and in the U.S. (the identifying
term being "Informatiyki Medycznej", and "Medical Informatics" respectively).
Today the International Medical Informatics Association has 54 dues-paying national associations as members.
Advanced Informatics in Medicine program in EU.
NIH-funded training programs at informatics “centers of excellence” (currently 18 funded programs).
The Association of American Medical Colleges (AAMC) has issued recommendations regarding the importance
of and the approaches needed for successful introduction of biomedical informatics education in US medical
HOW IMPORTANT IS HEALTH INFORMATICS AND
A small but indicative list of cornerstone medical
and bioresearch achievements that informatics
The Human Genome project
CAT-scans, and MRIs
Sequence alignment (e.g., BLAST)
GenBank & other research-critical databases
Microarrays, high throughput proteomics
Next generation sequencing
Molecular profiling and personalized medicine
UNIQUENESS OF NYU
World-class Medical center
But until 2008: no organized academic
Although the need is exponentially increasing
And researchers seek informatics service and
CENTER FOR HEALTH INFORMATICS & BIOINFORMATICS
CENTER FOR HEALTH INFORMATICS & BIOINFORMATICS
SELECTED CHIBI ACCOMPLISHMENTS: OCTOBER 2008-OCTOBER 2009
Enabled CTSA award to NYU (previously denied because of lack of informatics!)
Hired 5 new informatics faculty in critical new methods innovation and service areas
Brought together 15 total faculty and fostered common academic research, teaching and educational environment
Launched 3 new research informatics labs with cutting edge research
5 new staff hires and training of new and existing staff
High Performance Computing Phase I design & implementation completed and Phase II design completed
Launched integrated consultation service: Best Practices Informatics Consultation Service (BPIC)
Launched Research and Clinical Data Base Management service
Acquisition of computing infrastructure
Developed fiscally responsible and sustainable Business Plans with flexible cost recovery and several free service
components to researchers
Developed full range of next generation sequencing informatics capabilities to support all next generation sequencing
Developed extensive and in-depth working relationships with MCIT, CTSA, Genomics Center, CoEs, Cancer Center, and
numerous research labs
Secured extensive IP portfolio for free use at NYU
Launched comprehensive educational activities: tutorials, courses, seminars, invited speakers, resident training
Leading the charge for a powerful and cost-effective design of FDW and LIMS for all high-throughput data
Informatics participation in >30 grants
Launched comprehensive CHIBI web site
Launched benchmarking activities spanning sequencing informatics methods, and pathwhay analysis algorithms
Faculty grants management and career development: exceeding Dean’ standards & moving toward consistency with national
informatics RPT standards
Assembled external advisory board with distinguished advisors
>40 papers in peer-reviewed journals including highest-profile journals in biology, medicine and informatics
Published 1 book and contracted 2 more
GOALS FOR YEAR #2
High Performance Computing Phase II implementation
Design, defend and launch MS/PhD/ Post-Doctoral Training program in Health Informatics and Bioinformatics
Execute remaining faculty and staff hires & training
Move to final dry lab space
Launch walk-in BPIC stage 1 consultation
SoPs and Policies, white papers for BPIC and NG sequencing informatics
Issue FDW recommendations
Issue LIMS advisory report
Informatics faculty RPT advisory
Library informatics innovations and Library Collaborative
Remodel find-a-researcher methods and tools
Re-design biorepository informatics
Launch data mining unit and pilot projects
Further enhance NG sequencing informatics capabilities and expand R&D
Cancer Center Informatics Core
Continue and enhance education activities with new tutorials, speakers, and classes
Strengthen collaborations with Courant and other NYU entities
Complete current benchmarking cycle and launch new cycle
Broad informatics needs survey
Expand informatics faculty grant and paper portfolios; faculty career development
Explore regional informatics synergies
Expand Web presence functionality and information
First and foremost Dean B. Grossman and Vice Dean Lee without their support CHIBI
would not exist.
The CHIBI faculty, staff and trainees. Special thanks to Heidi Fitterling for organizing
Our colleagues at NYULMC and especially:
MCIT: Paul Conocenti, Nader Mherabi and their team
Webteam: Michael Mainiero, Matt Lisowski, and their team
Graphic designers: William Sommer & Korgun Maral
CTSI: Co-directors Drs. B. Cronstein and J. Hochman and their staff
Vice Dean S. Abramson
Department Chairs and Division Chiefs where informatics faculty is housed: especially Dr. M. Blaser, Dr.
D. Sabatini, Dr. D. Roth, Dr., B. Cronstein, Dr., Marc Gourevich.
The SPA office
The Cancer Center Director Dr. Bill Carroll and his associates
All our research collaborators, especially Drs Harry Ostrer, Ed Fisher, M. Blaser and their associates
The business & administration colleagues who are constantly helping CHIBI: especially Heidi Aronin,
Karen Berlinger, Keith O’brien, Swasti Raghava, Susan DiGeronimo Wild, Anne Crozat, the HR team,
Andrea Hines, Lyllian Mundo.
YUVAL KLUGER PH.D., DIRECTOR, KLUGER LAB
ALEXANDER ALEKESYENKO PH.D., MEMBER,
MOLECULAR SIGNATURES LAB
STUART BROWN PH.D., SENIOR INFORMATICS
FACULTY RESPONSIBLE FOR NEXT-GEN
ALEXANDER STATNIKOV PH.D., DIRECTOR
COMPUTATIONAL CAUSAL DISCOVERY LAB
THANK YOU AND ENJOY!