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					                                   Programme

WEDNESDAY, November 26

09.00 – 09.15         Opening
                      Dr. Nicolae Victor ZAMFIR
                      Prof. Dr. Rodica ANGHEL

Session 1
Chairmen: Dr. Renata Mikołajczak, Dr. Mariana Purice

09.15 – 09.45         Invited Lecture I1
                      Prof. Dr. Rodica Anghel

Targeted Therapy in Nuclear Medicine – Current Status and Future
Prospects
Rodica Anghel1, Dana Ples2
                      1
                        Institute of Oncology,” Prof. Dr. Al. Trestioreanu”, Bucharest
                 University of Medicine and Pharmacy “Carol Davila”, Bucharest


09.45 – 10.15         Invited Lecture I2
                      Dr. Dana Niculae

Radiolabelled Biomolecules for Targeted Radiotherapy of Cancer and
Inhibition of Angiogenesis
Dana Niculae1, Valeria Lungu1, Lorelei Brasoveanu2, Maria Iuliana Gruia3, Rodica
Anghel3, Marina Ilescu1, Diana Savu1
           1
            National Institute for Physics and Nuclear Engineering “Horia Hulubei”,
                                                                             Bucharest
        2
          Institute of Virology “Stefan S. Nicolau”, Immunology Center, Bucharest
                      3
                        Institute of Oncology,” Prof. Dr. Al. Trestioreanu”, Bucharest

10.15 – 10.45         Invited Lecture I3
                      Dr. József Környei
                                              Isotop Institute, Budapest, Hungary

Radiolabelled Biomolecules And Their Competitors For Nuclear
Medicine

10.45 – 11.15         Coffee break


Session 2
Chairmen: Dr. József Környei, Dr. Iuliana Maria Gruia
11.15 – 11.45        Invited Lecture I4
                     Dr. Renata Mikołajczak
              Polatom Radioisotope Centre, Institute of Atomic Energy, Warsaw

Therapeutic potential of radionuclides 90Y, 177Lu, 188Re. Production
possibilities and applications in nuclear medicine

11.45 – 12.05        O1
                     Dr. Maria Sahagia

Standardization of the therapeutical radionuclides
Maria Sahagia*, Anamaria Cristina Wätjen, E.L. Grigorescu, A. Luca, C. Ivan,     A.
Antohe

     National Institute for Physics and Nuclear Engineering “Horia Hulubei”,
                                                                  Bucharest
12.05 – 12.25        O2
                     Dr. Mariana Purice

Follow up of radio iodine therapy for patients with thyroid cancer
using BIOMAT- ENDO database software
Mariana Purice1, E. Marcu2, A. Goldstein1, Maria Belgun1, R. Purice3
                     1
                       National Institute of Endocrinology “C.I. Parhon”, Bucharest
                                                                2
                                                                  SOFTWIN Romania
            3
              Institute of Mathematics "Simion Stoilov" of the Romanian Academy

12.25 – 12.45        O3
                     Dr. Marina Iliescu

Click chemistry approaches in the synthesis of the radiopharmaceuticals
Marina Iliescu1, Dana Niculae1, Valeria Lungu1 and Corneliu Podina2
 1
   National Institute for Physics and Nuclear Engineering “Horia Hulubei”, Bucharest
                                                            2
                                                              University of Bucharest

12.45 – 13.05        O4
                          Dr. Constantin Lipsa

PH Monitoring and Concentration of Iodine Measurement from
Atmospheric Air
C. Lipsa1, Dorelia Simona Lipsa2, V.Ciupina1, Norina Consuela Forna3, Gica
Lehaci4
       1
         Department of Pharmacy, Ovidius University of Constanta, ROMANIA
                                                3
                                                  University “Gr.T.Popa” Iasi
                               4
                                 School “D.Cantemir”-A.M.G., Iasi, Romania

13.05 – 14.30        Lunch break
Session 3
Chairmen: Prof. Dr. Rodica Anghel, Valeria Lungu

14.30 – 14.50           O5
                        Dr. Iuliana Maria Gruia

Free radicals mediated citotoxicity induced by radiolabelled
biomolecules in targeted oncological therapy
Maria Iuliana Gruia1, Valentina Negoita1, Monica Vasilescu1, Marieta Panait1,
Dana Niculae2, Valeria Lungu2, Ion Gruia3
               1
                 Institute of Oncology,” Prof. Dr. Al. Trestioreanu”, Bucharest
      2
        National Institute for Physics and Nuclear Engineering “Horia Hulubei”,
                                                                        Bucharest
                         3
                           University of Bucharest, Faculty of Physics, Bucharest

14.50 – 15.10           O6
                        Dr. Lorelei Irina Brasoveanu

Biomolecules          Of      Potential      Clinical      Use     In     Cancer
Radioimmunotherapy
Lorelei Irina Brasoveanu1, Camelia Hotnog1, Mirela Hirt1, Mariana Claudia
Constantin1, Liliana Puiu2
   1
     Institute of Virology “Stefan S. Nicolau”, Immunology Center, Bucharest
                 2
                   Institute of Oncology,” Prof. Dr. Al. Trestioreanu”, Bucharest

15.10 – 15.30           O7
                        Dr. Irina Baran

Differential Effects of Proton- and γ-radiation on Cell Survival and
Proliferation
Irina Baran1, Ioan Ursu2, Constanta Ganea1
                    1
                      University of Medicine and Pharmacy “Carol Davila”, Bucharest
2
    National Institute for Physics and Nuclear Engineering “Horia Hulubei”, Bucharest

15.30 – 15.50           O8
                        Prof. Dr. Doc. Anica Dricu

Receptor tyrosine kinases as therapeutic targets in solid tumours
                                University of Medicine and Pharmacy Craiova
                     and Oncology Pathology, Karolinska Institute, Stockholm

15.50 – 16.15           Coffee Break

16.15 – 16.55           Presentation P1
                        Elena Pintica
                                                                               Medist
Thursday, November 27

Session 4
Chairmen: Dr. Ioannis Pirmettis, Dr. Laurentia Minea

09.00 – 09.20        O9
                     Dr. Valeria Lungu

      Radiolabelling of Neurotensin with 177Lu for peptide receptor
      targeted radiotherapy
National Institute for Physics and Nuclear Engineering “Horia Hulubei”


09.20 – 09.40        O10
                     Dr. Liviu Craciun

 [18F]FDG synthesis by an automated computer controlled system:
Improvements and general considerations
         National Institute for Physics and Nuclear Engineering “Horia Hulubei”

09.40 – 10.00        O11
                     Dr. Valentina Negoita

Experimental animal tumors as models implying the utilization of
radiolabeled molecules
Valentina Negoita, Maria Iuliana Gruia, Monica Vasilescu
                    Institute of Oncology,” Prof. Dr. Al. Trestioreanu”, Bucharest

10.00 – 10.20        O12
                     Dr. Laurentia Minea

Present clinical application of radioimmunotherapy in haematology
Laurentia Minea, Dana Ples
University of Medicine and Pharmacy “Carol Davila”, Bucharest

10.20 – 10.40        O13
                     Dr. Nicolae Verga

The role of  + emitter radionuclides in the differential diagnosis of the
skin cancers
                 University of Medicine and Pharmacy “Carol Davila”, Bucharest

10.40 – 11.15        Coffee break
Session 5
Chairmen: Dr. Christian I. Chiricuta, Dr. Lorelei I. Brasoveanu

11.15 – 11.45        Invited Lecture I5
                     Dr. Ioannis Pirmettis
                                     Demokritos National Research Center, Athens
                           Institute of radionuclides and Radiodiagnostic Products
99m
      Tc complexes for tumour imaging and sentinel lymph node detection

11.45 – 12.05        O14
                     Dr. Valeria Lungu

Targeted Radionuclide Therapy
  Horia Hulbei National Institute for Physics and Nuclear Engineering Bucharest-
                                                                       Magurele

12.05 – 12.25        O15
                     Dr. Diana Savu

Chromosomal radiosensitivity of peripheral blood lymphocytes in cancer
patients
Diana Savu1, S. Cinca2, Rodica Anghel2, Ileana Petcu1
 1
   National Institute for Physics and Nuclear Engineering “Horia Hulubei”, Bucharest
                      2
                        Institute of Oncology,” Prof. Dr. Al. Trestioreanu”, Bucharest

12.25 – 12.45        O16
                     Dr. Radu Fumarel

[99mTc] pteridinic derivatives: Determination of pharmacokinetics of
MTX (used as a photosenzitizer in PhotoStimulated Chemotherapy
protocols) by scintigraphyc monitoring
R. Fumarel1, Mirela Gherghe1, Anca Hurduc1, P. Albert1, M.L. Pascu2, N. Stafidov
                     Institute of Oncology,” Prof. Dr. Al. Trestioreanu”, Bucharest
          2
            National Institute for Laser, Plasma and Radiation Physics, Bucharest

12.45 – 13.05        O17
                     Dr. Raluca Mititelu

Multiple Myeloma. Combined Use of 99m-Tc-MIBI Scan and MRI for
Evaluation of Active Lesions
R. M. Mititelu, G. Marinescu, M. Iriciuc, A. Rimbu, S. Ghita, C. Mazilu, P.
Murgoci, I. Codorean
                        Central Clinical Emergency Military Hospital, Bucharest
13.05 – 14.00      Lunch break

Session 6
Chairmen: Prof. Dr. Anica Dricu, Dr. Marina Iliescu

14.00 – 14.20   Presentation P2
            Dr. Radu Vasilache

Cyclone storage phosphors & gamma spectroscopy versus
radio TLC as methods for molecular and isotopical purity
checking in radiopharmaceuticals production
                                         Canberra Packard

14.20 – 14.40    O18
            Dr. Liviu Craciun

A New Research Center for Radiopharmaceuticals in IFIN-
HH
   National Institute for Physics and Nuclear Engineering “Horia
                                                        Hulubei”

14.40 – 15.00   O11
            Dr. Mihai Radu

BioEval facilities for evaluation of radiopharmaceuticals
toxicity and materials biocompatibility
C. Mustaciosu, Diana Savu, Ileana Petcu, Dana Niculae, Valeria Lungu,
M.Radu
      National Institute for Physics and Nuclear Engineering “Horia
                                                Hulubei”, Bucharest

15.00 – 15.30      Coffee break

Session 7
Chairmen: Dr. Ioan Ursu, Dr. Dana Niculae

15.30 – 15.50      O20
                   Lidia Matei

In vitro and in vivo radiometrical studies for evaluation of new
nucleoside analogue behaviour
Lidia Matei, Gina Manda, C. Postolache, C.V. Tanase, G. Bubueanu, Diana
Chiper
1
  National Institute for Physics and Nuclear Engineering “Horia Hulubei”,
                                                          Bucharest
         2
             National Institute of Biology and Cellular Pathology V. Babes,
                                                                 Bucharest
              3
                Institute for Chemistry and Pharmacy Research, Bucharest



15.50 – 16.20    Invited Lecture I7
            Prof. Dr. I. C. Chiricuta
   Institute of Radiation Oncology, St.Vicenz-Hospital, Limburg,
                                                        Germany
The Sentinel Node Navigation Radiotherapy


16.20 – 16.50         Invited Lecture I8
                       Prof. Dr. Roberto Pasqualini
                                        IBA Molecular, Paris
Nuclear medicine: an analysis of the present, a look
towards the future


18.00 – 20.00         Dinner at Hotel Caro




Friday, 28 November

09.00 – 11.00     Visit to IFIN-HH (Radiopharmaceuticals
Dept., BioEval Laboratory, IRASM)

11.00 – 12.00          Conclusions / Discussion

12.00 – 13.00          Lunch

				
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