The exact mechanism of action of corticosteroids in the management of asthma is unknown; however, they have been shown to have a wide range of activity against mediators of inflammation involved in the inflammatory response seen with asthma. If adrenal insufficiency exists following systemic corticosteroid therapy, replacement with inhaled corticosteroids may exacerbate symptoms of adrenal insufficiency (eg, lassitude). Headache, nasopharyngitis, sinusitis, throat pain, upper respiratory infection, arthralgia, nasal congestion, back pain; rare: bronchospasm, immunosuppression, glaucoma, cataracts, oral candidiasis, decreased bone mineral density.
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