To test the safety and effectiveness of an upper extremity resistive exercise program for breast cancer survivors that can be done in the home. Fourteen women with stage I or II breast cancer at least 6 months post surgery, radiation, and chemotherapy. Women were individually seen in an ABA single subject design over 15 weeks with 4-week baseline, 8-week intervention, and 3-week follow-up phases. The intervention consisted of 6 upper extremity resistive exercises using free weights. Weights were advanced using a calculated 1 Repetition Maximum (1 RM). Data were pooled for a case series analysis. There was a significant increase in the calculated 1 RM for all of the 6 exercises (p .05). There were no significant changes in arm volume (p .05). Quality of Life data significantly changed on 4 subscales (p .05). Specific parameters of intensity, frequency, and duration for an upper extremity resistive exercise program for women with breast cancer are described. Participants increased the amount of weight lifted, did not develop lymphedema, and had improved emotional qualities of life.