Road crashes now are the leading cause of death worldwide for children and young people aged 10 to 24. By 2015, the World Health Organization predicts that in developing countries, deaths and injuries on the roads will top its disability-adjusted life-years list for children aged four and older. This spring, for the first time, the United Nations (UN) will be debating road safety in its General Assembly plenary session. Key components of this resolution are: holding a UN-sponsored ministerial meeting to gain worldwide government support for road safety; dedicating 5% to 10% of future road-building project costs to safety; and specific action plans that include improved policies for road users, better vehicles and safer road design for pedestrians, cyclists and drivers. In addition to technical and scientific knowledge, this global road safety effort will require political commitment.