India today presents a very mixed story compared to other emerging Asian economies. It is a major emerging center for research and development yet its domestic infrastructure and expenditures do not fully support its ambitions. Several important factors are working in India's favor. One of the most important is India's strong basic research capacity. India has among the most researchers in the world. More than 300 multinational corporations already have set up R&D and technical centers in India. However, India's 2004 spending on R&D was only $5.4 billion, but if measured in terms of purchasing power parity it was $26.9 billion and ranked ninth in the world. The problem facing the practice of scientific research and application in India is not the lack of skilled manpower. The greatest concerns are structural ones, the lack of an efficient relationship among various elements of its science & technology system.