[...] the general impression is that the CT information would significantly increase the diagnostic accuracy, particularly the specificity. From a subgroup analysis of our study, we concluded that planar V/Q lung scintigraphy had a specificity of 72%. which is still higher lhan the specificity of perfusion SPECT in combination with low-dose CT (2). [...] omitting the low-dose CT and using only perfusion SPECT would probably result in a low specificity and too many false-positive diagnoses.
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