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American Nurses Association - An Overview of Enzyme Replacement Therapy for Lysos... Page 1 of 9 An Overview of Enzyme Replacement Therapy for Lysosomal Storage Diseases Laurie Bailey, MS, CGC Abstract The lysosomal storage diseases (LSDs) are a group of disorders heralding in a new era in the treatment of genetic diseases. Enzyme replacement therapy (ERT) moves the treatment of these disorders from symptomatic management to therapeutic interventions. ERT is not a cure for these disorders, but it can greatly modify or attenuate the phenotype. Treatment for LSDs is
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