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					                              Kimberly A. Greer
                                 4302 Bentwood Drive
                               College Station, TX 77845
                                Office: (979) 458-0128
                              Laboratory: (979) 862-2014
                                 Home: (979) 690-9023
                         Electronic mail: kgreer@cvm.tamu.edu
                         Citizenship: United States of America
Education:
     Texas A&M University, College Station, Texas
     Doctor of Philosophy, Genetics, May 2002
     Texas A&M University, College Station, Texas
     Master of Science, Genetics, December 1996
     Texas A&M University, College Station, Texas
     Bachelor of Science, Genetics, December 1992

Research Experience:
     Texas A&M University, Department of Veterinary Pathobiology; College Station, Texas
     Research Assistant Professor, January 2005-present
         laboratory focus is on canine hereditary disease and aging/ longevity
         techniques include a wide variety of molecular biology and molecular genetic
            techniques
         teach undergraduates laboratory methods, techniques, and theory
         serve on graduate committees
         guest lecture in public venues, veterinary courses, and undergraduate courses

     Texas A&M University, Department of Veterinary Pathobiology; College Station, Texas
     Assistant Research Scientist, May 2002- January 2005
     Postdoctoral appointment; funded by NIH F32 fellowship (KA Greer, PI)
         directed day to day activities of 13 member laboratory
         provided undergraduate and graduate student project guidance and instruction
         designed and carried out aging and longevity studies
         designed and carried out necrotizing encephalitis studies
         established largest database and biological specimen set for Pug Dog Encephalitis
         established canine DNA bank of 170+ independent breeds
         obtained grant funding for projects (as PI)
         wrote, edited, and published manuscripts

     Eli Lilly and Company, Investigative Toxicology; Greenfield, Indiana
     Visiting Scientist, June 2003- July 2003
          completed microarray project utilizing a proprietary Affymetrix canine oligo
             array
          isolated canine RNA from various tissues, synthesized cRNA, performed chip
             hybridization, evaluated resulting data
          wrote manuscript of results and published in Mammalian Genome
                                                                                Greer- 2
Genetic Savings and Clone, College Station, Texas
Consultant, April 2002- May 2002
    instructed graduate and undergraduate students in laboratory theory and
       techniques
    designed and guided student research projects
    evaluated standard operating procedures, proposed new methodology to operate
       the laboratory more efficiently; significantly reduced laboratory operating cost

Texas A&M University, Veterinary Anatomy and Public Health; College Station, Texas
Graduate Research Assistant, January 1997- August 1999
    conducted independent research
    evaluated various populations of people for susceptibility to neural tube defect
      transmission
    evaluated the effects of folate supplementation on decreased risk of neural tube
      defects in susceptible murine models
    evaluated murine tissue expression of folate binding proteins and the reduced
      folate carrier
    established an in vitro model for evaluating intracellular effects of oxidative stress
    trained graduate students and professional students
    trained and supervised technicians and undergraduates

National Institutes of Health, National Human Genome Research Institute; Bethesda,
Maryland
Visiting Scientist, March 1998-July 1998
    conducted linkage analysis on F1 hybrid mice to correlate genes with
        developmental toxicology of Phenobarbital
    presented research findings
    transferred technology to laboratory in Texas

Texas A&M University, Veterinary Anatomy and Public Health; College Station, Texas
Research Assistant II and Lab Manager, January 1995- December 1996
    isolated, sequenced, and characterized the Reduced Folate Carrier 1 gene in the
       murine
    set up laboratory RNA isolation lab, experimental techniques, and standardized
       methodology

Texas A&M University, Veterinary Anatomy and Public Health; College Station, Texas
Research Assistant I and Lab Manager, December 1992- December 1994
    responsible for maintenance and propagation of laboratory plasmid stocks
    maintained murine breeding colony
    treated murine colony with targeted anticonvulsant drugs
    evaluated the efficacy of steripentol (STP) for FDA consideration
    trained graduate, professional, and undergraduate students in laboratory
       techniques and murine colony maintenance
                                                                                   Greer- 3
      Texas A&M University, Veterinary Anatomy and Public Health; College Station, Texas
      Student Research Assistant, August 1992- December 1992
          responsible for maintenance and propagation of laboratory plasmid stocks
          maintained murine breeding colony
          treated murine colony with targeted anticonvulsant drugs

      Texas A&M University, Entomology, College Station, Texas
      Student Research Assistant, December 1991- August 1992
          responsible for maintenance and propagation of laboratory plasmid stocks
          cloned and subcloned genes pertaining to

Teaching Experience:
      Texas A&M University, College of Veterinary Medicine; College Station, Texas
      Teaching Assistant: Biochemical Genetics, September 1999- December 2001
          lectured each semester
          offered tutorial lectures twice per week
          offered additional office hours for individual assistance
          wrote exam questions
          graded examinations and weekly quizzes

      Texas A&M University, Department of Biochemistry and Biophysics; College Station,
      Texas; Teaching Assistant: Genetics 301 Laboratory, January 1996-May 1996
          lectured twice weekly
          wrote weekly laboratory evaluations and quizzes
          graded weekly laboratory performance and quizzes
          offered office hours for individual assistance

Publications:
    Greer, K.A., S. Canterberry, K. Murphy. 2007. Statistical analysis regarding the effects of
    height and weight on lifespan of the domestic dog. Research in Veterinary Science 82(2):
    208-214.

    Pine M.D., K.A. Greer, D. Busbee. 2007. Comparison of Reactive Oxygen Scavenging
    Systems between a Cetacean (DKN1) and a Porcine Renal Epithelial Cell Line (LLC-PK1).
    Comparative Biochemistry and Physiology 147: 550–555
    .
    Greer, K.A., M. Higgins, M. Cox, T.P. Ryan, B.R. Berridge, C.E. Kashtan, G.E. Lees,
    K.E. Murphy. 2006. Gene Expression Analysis in a Canine Model of X-linked Alport
    Syndrome. Mammalian Genome 17(9): 976-990.

    Greer, K.A., M. Pine, D. Busbee. 2005. An in vitro model of excess intracellular reactive
    oxygen species. AGE 27(2): 97-105.
                                                                             Greer- 4
Canterberry, S.C.*, K.A. Greer*, C. Hitte, C. Andre, K. Murphy. 2005. Aging-associated
loci in Canis familiaris. Growth, Development, and Aging 69 (2): 101-113; *indicates
equal authorship.

Lundberg, Y.W., Cabrera R.M.*, Greer K.A.*, Zhao J, Garg R, R.H. Finnell. 2004.
Mapping a chromosomal locus for valproic acid-induced exencephaly in mice. Mammalian
Genome 15: 361-369; *indicates equal authorship.

Greer, K.A., E.J. Cargill, M.L. Cox, L.A. Clark, K.L. Tsai, K.M. Credille, R.W. Dunstan,
P.J. Venta and K.E. Murphy. 2003. Digging up the canine genome – a tale to wag about.
Cytogenetic and Genome Research 102(1-4): 249-253.

Pine, M., M. Schroeder, K. Greer, R. Hokanson, and D. Busbee. 2003. Generation and
Partial Characterization of a Transformed Cetacean Cell Line. Aquatic Toxicology 67(4):
195-202.

Barber, R.C., G.D. Bennett, K.A. Greer, R.H. Finnell. 1999. Expression patterns of folate
binding proteins one and two in the developing mouse embryo. Molecular Genetics and
Metabolism 66(1): 31-39.

Barber, R.C., E.J. Lammer, G.M. Shaw, K.A. Greer, R.H. Finnell. 1999. The role of folate
transport and metabolism in neural tube defect risk. Molecular
Genetics and Metabolism 66(1): 1-9.

Barber, R.C., G.M. Shaw, E.J. Lammer, K.A. Greer, T.A. Biela, S.W. Lacey, C.R.
Wasserman, R.H. Finnell. 1998. Lack of Association between Mutations in the Folate
Receptor- Gene and Spina Bifida. American Journal of Medical Genetics 76(4): 310-
317.

Finnell, R.H., K.A. Greer, R.C. Barber, J.A. Piedrahita. 1998. Neural tube and
craniofacial defects with special emphasis on folate pathway genes. Critical Reviews in
Oral Biology Medicine 9(1): 38-53.

Greer, K.A., P.E. Bonnen, N. Jimenez, E.J. Lammer, S.W. Lacey, G.M. Shaw, and R.H.
Finnell. 1995. Folate receptor gene variants and neural tube defect occurrence. Teratology
51(3): 162.

Finnell, R.H., K.A. Greer, E. Lammer, S. Lacey, G. Shaw. 1994. Folate receptor gene
variants and neural tube defect occurrence. American Journal of Human Genetics 55(3):
870.

Musselman, A.C., G.D. Bennett, K.A. Greer, J. Eberwine, R.H. Finnell. 1994. Preliminary
evidence of phenytoin-induced alterations in early embryonic gene expression in a mouse
model. Reproductive Toxicology 8(5): 383-395.
                                                                                Greer- 5
Bennett, G.D., K.A. Greer, R.H. Levy, J. Slattery. 1993. Stiripentol protection from the
teratogenic effects of phenytoin and carbamezapine. Teratology 47(5): 406.

                      Submitted/In Preparation Manuscripts:
Greer, K.A., S.J. Schatzberg, B.F. Porter, K.A. Jones, T.R. Famula, K.M. Murphy.
Heritability and transmission analysis of Pug Dog Encephalitis. (in prep, Journal of
Veterinary Medicine)

Greer, K.A., P.W. Daly, W. Ji, K. E. Murphy, J. J. Callanan. Etiological determination of
breed specific meningoencephalitis via gene expression analyses. (in prep, Journal of
Neuroinflammation).

White, J., J. Levine, B. Porter, S. Schatzberg, K.A. Greer. Magnetic resonance imaging
characterization of confirmed Pug Dog Encephalitis. (in prep, Journal of Veterinary
Medicine)

Porter B., R. Storts, J. Levine, K.A. Greer. Distinguishing histopathology of Pug Dog
Encephalitis compared to granulomatous meningoencephalitis. (in prep, Journal of
Veterinary Medicine).

Greer, K.A., S.C. Canterberry, K.E. Murphy. Longevity associated, breed specific single
nucleotide polymorphisms in C. familiaris. (in prep, AGE).

                                     Abstracts:
Greer, K.A., R.H. Finnell, W. Pavan, L.G. Biesecker. 1998. Linkage mapping of a major
susceptibility locus for valproic acid induced neural tube defects in the mouse. American
Journal of Human Genetics 63(4): A1684.

Greer, K.A., J.A. Piedrahita, G.D. Bennett, B. Oetama, R.H. Finnell. 1997. Expression of
the murine folate binding proteins 1 and 2 and the reduced folate carrier gene. American
Journal of Human Genetics 61(4): A993

Barber, R.C., G.D. Bennett, K.A. Greer, R.H. Finnell. 1997. Expression of folate binding
proteins one and two in the SWV/Fnn mouse. American Journal of Human Genetics 61(4):
A166.

Greer, K.A., J. Piedrahita, B. Oetama, B. Barber, R. H. Finnell. 1996. Isolation and
characterization of the reduced folate carrier in the murine system. American Journal of
Human Genetics 59(4): A2137.

Barber, R.C., K. A. Greer, G.M. Shaw, C.R. Wasserman, E.J. Lammer, R.H. Finnell.
1996. Screening methods for unknown polymorphisms: dideoxy fingerprinting (ddF) vs.
single stand conformational polymorphism (SSCP). American Journal of Human Genetics
59(4): A212.
                                                                                     Greer- 6
Mentorship:
     Graduate student committee
           Sarah Zienko, Genetics
     Undergraduate supervisor and research mentor
           Kimberly Jones, Biomedical Science, currently enrolled at TAMU School of
                  Veterinary Medicine
           Mary Wallace, Animal Science, currently applying for graduate school
           Jennifer Wickline, Biomedical Science, currently applying for vet school
           Robert Shaw, Poultry Agriculture
           Sharon Ulah, Biomedical Science

Invited Lectures:
     Pug Dog Club of America, National Specialty, San Antonio, TX; September 2005
     Necrotizing Meningoencephalitis: Our Latest Accomplishments
     Towards Transmission Analysis

     Borzoi Club of the United States of America, National Specialty, Dallas, Texas; April
     2005
     Canine Genetic Developments and Borzoi Health

     Pug Dog Club of America, National Specialty, Olympia, Washington; September 2004
     The Past, Present, and Future of Necrotizing Meningoencephalitis Research.

     Veterinary Histology, College Station, Texas; April 2004, April 2002
     A Day in the Life of an Insulin Dependent Diabetic.
     Pug Dog Club of Greater San Antonio, Regional Specialty, San Antonio, Texas;
     March 2004
     Recent Advances in Transmission Analysis of Necrotizing Meningoencephalitis in the
     Pug Dog (PDE).

     Pug Dog Club of America, National Specialty, Sturbridge, Massachusetts; October
     2003
     Transmission Analysis of Necrotizing Meningoencephalitis in the Pug Dog (PDE).

     Old English Sheepdog National Specialty, Waco, Texas; October 2002
     Understanding Hereditary Diseases of the Domestic Dog: A Tale of Two Approaches.

     March of Dimes Lecture Series, Bryan High School Child Development, Bryan,
     Texas; April 1996
     The various causes of birth defects and how we can prevent the preventable defects.

     Genetics Laboratory, College Station, Texas; April 1996
     Methodologies for Producing Transgenic Animals.
                                                                               Greer- 7
Texas Department of Health, Austin, Texas; July 1994
The Implications of Folate Supplementation.

Human Genetics College Station, Texas; April 1994
The Incidence of Neural Tube Defects on the Texas-Mexico Border.

                             Academic Conferences:
Gordon Research Conference, Biology of Aging, Ventura, CA; February 2006
Deciphering Mechanisms of Aging in C. familiaris
(Selected as one of ten from 75 posters)

Marine Biological Laboratories, Molecular Biology of Aging series, Woods Hole,
MA, August 2004;
Optimization and utilization of the comet assay for evaluating DNA repair in mammalian
aging.

American Aging Association, Oakland, California; June 2005
Investigation of the Domestic Dog (Canis familiaris) for Determination of Genetic
Factors in Longevity

Nathan Shock Aging Center Conference on Aging: Oxidative Stress, Bandera,
Texas; October 2004
Understanding the genetics of aging: a canine model.

American Aging Association, St. Petersburg, Florida; June 2004
Understanding the genetics of aging: a canine model

International Workshop on Dog Genetics, Uppsala, Sweden; May 2002
Genetic Analysis of Canine X-linked Alport Syndrome in a Family of Mixed Breed
 Dogs.

National Institutes of Health, Bethesda, Maryland; July 1998
Linkage mapping of a major susceptibility locus for VPA-induced NTDs utilizing a
whole genome scan of a backcross system.

American Association of Human Genetics, Baltimore, Maryland; October 1997
Expression of the Murine Folate Binding Proteins 1 & 2 and the Reduced Folate Carrier
Gene.
March of Dimes and the American College of Medical Genetics, Joint Clinical
Meeting, San Antonio, Texas; March 1996
Folate Receptor Gene Variants: Implication for Susceptibility to Neural Tube Defects.

March of Dimes Conference, San Antonio, Texas, March 1994
Neural Tube Defects and Folate Supplementation.
                                                                                       Greer- 8
      Awards:
      Gordon Research Conference, Biology of Aging, Ventura, California; February 2006
      Poster Presenter: Oxidative stress mechanisms of aging in C. Familiaris

      Marine Biological Laboratories Course Fellowship; Molecular Biology of Aging,
      Special Topics Course, August 2004
      Ellison Medical Foundation international competition for attending its fully sponsored
      lecture and laboratory course (three week course) Woods Hole, Massachusetts;

      Summer Institute on Aging Research Award, Queenstown, Maryland; July 2004
      NIH/NIA national competition for attending its fully sponsored summer institute
      (one week course)

      NIH/NIA, National Research Service Award Postdoctoral Fellowship, 2003-2005
      Understanding Genetics of Aging: Canis familiaris model

      Lexington Who’s Who, Association of Business Leaders and Professionals, 2000

      Gamma Sigma Delta, The Honor Society of Agriculture 1998-2001

      Center for Environmental and Rural Health, Graduate Research Assistantship
      1997-1998

Professional Affiliations:
      American Aging Association; 2004-present
      American Association for the Advancement of Science; 1998-present
      American Association of University Women; 1996-present
      Texas A&M University, Graduate Faculty; 2003-present
      Texas Genetics Society; 2003-present

Professional Services:
      Journal reviews: Cytogenetic and Genome Research, Genomics, Mammalian Genome
      Proposal reviews: Wellcome Trust, American Kennel Club-Canine Health Foundation
      Texas Veterinary Diagnostic Center, Emergency Response Laboratory Reserve Force

Grant Awards:
      AKC-CHF, Grant No. 640 (PI)
      Linkage Disequilibrium Analysis of Markers Associated with Pug Dog Encephalitis;
      2006-2008

      Texas A&M University, Vice President for Research Travel Award (PI)
      Preliminary examination of oxidative stress methanimsms of aging in C. familiaris;
      2005-2006
                                                                                     Greer- 9
     NIH/NIA, F32 National Research Service Award (PI)
     Understanding Genetics of Aging: Canis familiaris model; 2003-2005

     Greater St. Louis Pug Dog Club, Research Grant Award (PI)
     Club award towards Transmission Analysis of Breed Specific Necrotizing Encephalitis
     in the Pug Dog: Collection Phase; 2002-2003

     AKC-CHF, Grant No. 2650 (Co-PI)
     Transmission Analysis of Breed Specific Necrotizing Encephalitis in the Pug Dog;
     2003-2004

     Pug Dog Club of Northern CA, Research Grant Award (PI)
     Club award towards Transmission Analysis of Breed Specific Necrotizing Encephalitis in
     the Pug Dog: Collection Phase; 2002-2003

     AKC-CHF, Grant No. 2501 (PI)
     Transmission Analysis of Breed Specific Necrotizing Encephalitis in the Pug Dog:
     Collection Phase; 2002-2003

     Awards Pending: (Proposals to be submitted 2006-2007 fiscal year)
     NIA R03: PA-03-067 (PI)
     Age-related changes in tissue function; 2007-2009
     NINDS/ NIA R21: PAS-03-092 (PI)
     Gene discovery in a complex neurological disorder; 2008-2009
     Waltham Foundation (PI)
     Dietary modification of oxidative stress to lend healthy extended longevity; 2007-2009
     Center for Environmental and Rural Health, Pilot Projects (PI)
     Oxidative stress effects on healthy aging and longevity; 2007-2008
     Whitehall Foundation
     Necrotizing encephalitis, cytokines, dementia, and disorientation; 2007-2009
     Morris Animal Foundation
     Molecular genetic analyses of canine necrotizing encephalitis; 2007-2008
     Graduate Women in Science
     Molecular mechanisms of aging influenced by oxidative stress exposures; 2007-2008
     Texas Higher Education Coordinating Board (PI)
     Cellular senescence associations with environmental oxidative stressors; 2007-2008

Community Involvement:
     Leaps N Bounds Agility Center; 1999- present
     Pug Dog Club of Greater San Antonio; 2001- present
                                                                      Greer- 10
Forest Ridge Elementary PTO; 2005- 2006
Pug Dog Club of America, 2005 National Organization Committee; 2003-2005
Brazos Valley Montessori School Parent Council; 2003-2005
Pug Rescue of Southeast Texas, PRoSET
Member 1997-2004
Executive Board Member 1997-2002
Adoption Committee Chair 2000-2002

Brazos Valley Montessori School
2004 Spring Discovery Fair Chairman; 2003- 2004
(community-wide school fundraiser)
Puppy Love Dog Obedience and Behavior Center, Agility Trainer; 2002
College Station Middle School Science Fair Judge; 2001
Brazos Valley Kennel Club; 1998-1999

				
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