College Preparatory Biology

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					                                     College Preparatory Biology

                                                  2009-2010
UNIT ONE – THE MATTER OF LIFE

Learning Experience #1

Living Proof



Organism

Biotic

Abiotic



Activity:             Living or Nonliving

Reading:              Aliens: The Search for Extraterrestrial Life

                              –       reading and analysis questions

Teacher Direction     8 characteristics of life

Experiment            Plant radish seeds for LE3



Learning Experience #2

Which Way Do They Go?



Hypothesis

Metabolic processes



Activity:             Where is the Light?

                              -   response to environment
                              -   analysis questions

Reading               What’s Your Response?

                              -   Analysis questions
Learning Experience #3

Everything Under the Sun

Photosynthesis

Xylem

Phloem

Stomata

Chlorophyll

Solar energy

Variable

Positive control

Chemical reaction

Reactant

Product

Food

Disaccharide

Polysaccharide

Starch

Biomolecule



Task                Concept Map

                           -   Box key words, use arrows with arrow heads and linking words
                               (no more than 3 linking words)
                           -   Review photosynthesis; obtaining and using nutrients

Activity            You Light Up My Life

                           -   Learn vocabulary from reading

Reading             How Does Your Garden Grow?

                           -   Emphasize where matter comes from

Reading             Sunlight Becomes You
                              -   Read and pick out words for concept map (more than bold words)
                              -   light dependent and light independent variables



Learning Experience #4

Feeding Frenzy

Essential nutrient

Nutrient

Indicator

Negative control

Independent Variable

Dependent Variable

Fat

Lipid

Carbohydrate

Glycogen

Translucent



                       Prologue and Brainstorming

Activity               What am I Eating Anyway?

                              -   Pre-lab questions Stop and Think

Reading                The Missing Ingredients

                              -   Emphasize biomolecules (including glycogen), what happens to your body
                                  when you don’t get nutrients needed



Learning Experience #5

The Lego of Life

Elements

Molecule
Atom

Electron

Proton

Neutron

CHOPSN

Carbohydrate

Simple sugar/monosaccharide

Protein

Amino acid

Lipid

Glycerol

Fatty acids

Nucleic acid

Nucleotide

DNA

RNA



Reading             Madam, I’m Atom

                           -   Homework questions

Activity            A Mere Six Ingredients

                           -   Worksheets on biomolecules

For Further Study   The Ins and Outs of the Digestive System

                           -   Digestive system comparisons (include earthworm, bird and human digestive
                               systems)
                           -   Emphasize digestion to break down molecules
                           -   Emphasize form to function (food converted to biomolecules)

Experiment          Shark Dissection

                           -   Emphasize digestive structures
Learning Experience #6

Turning Corn into Milk: Alchemy or Biochemistry

Glucose

Lactose

Organic

Catabolism

Anabolism

Oxidized

Metabolism

Intermediate



Activity                Corn and Milk: So Different Yet So Similar

                               -   Analysis questions

Reading                 Haven’t I Seen That Carbon Somewhere Before?

                               -   Reading with diagram aides on Putting it All Together
                               -   Concept map p. 62



Learning Experience #7

A Breath of Fresh Air

Glycolysis

Pyruvate

Adenosine triphosphate (ATP)

Cellular respiration

pH




Activity                What Goes In…….

                               -   Analysis questions
                               -   Emphasize how CPR can occur
                               -   Reinforce nitrogen fixation

Activity                ……..Must Come Out

                               -   Crickets vs. yeast (or radish seeds)
                               -   Positive and negative controls vs. variables

Reading                 Energy for All

                               -   analysis questions a-h
                               -   analysis questions #3 and #4



Learning Experience #8                   DO NOT DO THIS EXPERIENCE



Learning Experience #9

How Did It All Begin?

Evolution

Aggregate

Microspheres

Liposome




Activity                A Long, Long Time Ago

                               -   Order event time cards (no need to memorize dates)

Activity                The Bubbling Cauldron

                               -   Do procedure #3

Reading                 The Spark of Life

                               -   analysis questions



Learning Experience #10

Night of the Living Cell
Cell

Prokaryote

Eukaryote

Organelle

Endocytosisi

Cell membrane

Cytoskeleton

Cytoplasm

Cell wall

nucleus

Nuclear membrane

DNA/chromosome

Nucleolus

Mitochondria

Golgi apparatus

Ribosomes

Rough endoplasmic reticulum

Smoot endoplasmic reticulum

Chloroplasts

Vesicles

Vacuoles

Cilia/flagella

Lysosome




Library Work        “Cells Alive” website and additional websites

                              -   Gather information on cell structures
                              -   Summarize cell structures
Activity            The Whole Cell and Nothing but the Cell

                           -   Cell project with rubric (project can be done as individual or group; bring in
                               materials to class)
                           -   Emphasize interconnections between cell structures

Readings            As the Cell Turns

Reading             An Organelle with a View

For Further Study   Holding It All Together

                           -   cell membranes

Experiment          Soap Bubbles and Cell Membranes



Learning Experience #11

The Great Divide

Interphase

Mitosis

Prophase

metaphase

Anaphase

Telophase

Cytokinesis

Chromosomes

Chromatids

Spindle fibers



Activity            Soaking It All In

                           -   Tie into cell membranes, prokaryotes and eukaryotes

Reading             Divide a Conquer: A First Look

Activity            Divvying Up the Goods; Part A and Part B

                           -   Pipe cleaner activity
Reading              Divide and Conquer: A Second Look

Learning Experience #12            DO NOT DO THESE LEARNING EXPERIENCES

Learning Experience #13



UNIT 3: THE BLUEPRINTS OF INFECTION

Learning Experience #1

Disease Detectives

Reading              Cholera

Activity             Investigating the Nature and Cause of Cholera

Reading              Snow on Cholera: Data Collection

Reading              Snow on Cholera: Experimental Evidence

Reading              A Proper Place to Begin

Activity             Outbreak in Pickle City/Disease Transmission Lab



Learning Experience #2

Epidemic!

Reading              The End of the World is Nigh

Activity             Outbreak



Learning Experience #3

Agents of Disease

Communicable

Disease

Virus

Parasite

Infectious agent

Pathogen
Koch’s postulates

Host

Bacteria

Cocci

Bacilli

Spirochete

Antibiotic

Viricidal

Vaccine

Symbiosis

Protozoa

Fungi

Immune system

Antibodies

White blood cells




Activity               Case of the Killer Congestion

                              -   viral replication



Learning Experience #4

Search for the Cause

Reading                Griffith’s Search for the Cause

Activity               In Isolation

Experiment             DNA Extraction from Wheat Germ



Learning Experience #5
Language of the Cell

Activity               Building DNA

Activity               DNA as a Coded Plan

                              -   notes on DNA and DNA Replication

Learning Experience #6

Nucleic Acid to Protein

Activity               Dances with Ribosomes

Learning Experience #7

Protein, the Wonder Ingredient

Reading                Protein, Protein Everywhere

Activity               Liver and Let Liver

                              -   Do as reading, but not as experiment



Learning Experience #8        DO NOT DO THESE LEARNING EXPERIENCES

Learning Experience #9

Learning Experience #10 (done in LE3)

Learning Experience #11



Learning Experience #12

Immune System to the Rescue

Major Histocompatability Complex (MHC)

Lymphatic system

Antigens

Macrophage

Helper T-cell

Killer T-cell

B-cell
Antibody

Memory B-cell

Cell-mediated response

Humoral response

Interleukin 1

Cytokines



Activity             The Competition

Reading              The Pathogens Are Coming!

Reading              You Make Me Sick (But I Still Need You): A First Look

Activity             Confrontation

Reading              You Make Me Sick (But I Still Need You): A Second Look

                           -     vaccines



Learning Experience #13              DO NOT DO THESE LEARNING EXPERIENCES

Learning Experience #14



UNIT #2: TRAITS AND FATES

Learning Experience #1

Finding the “Gene” in Genetics

Genetics

Gene

Trait

Recessive trait

Dominant trait

Variant

Progeny
Reading             The Blue People of Troublesome Creek

                            -   gene to protein



Learning Experience #2

Inherit the Trait

Activity            Date, Mate?

                            -   Plant seeds for Option Two: Mustard Plants



Learning Experience #3

No Matter What Your Shape

Fertilization

Germination

Endosperm

Cotyledon

Dormant

Viable

Heterozygous

Homozygous



Activity            A Pea By Any Other Name is Still a Seed

                            -   Make connections between protein, enzyme and genes

Case Study          Am I a Carrier, and What Does That Mean?

                            -   Use table 2.1
                            -   analysis questions



Learning Experience #4      DO NOT DO THESE LEARNING EXPERIENCES

Deoxyribonucleic acid
Deoxyribose

Nucleotide

Nitrogen base

Adenine

Guanine

Cytosine

Thymine

Purines

Pyrimidines

Bacteriophage

Double helix

Complementary bases



Learning Experience #5

Ribonucleic acid

Ribose

Uracil

Messenger RNA

Transfer RNA

Ribosomal RNA

Transcription

Translation

Triplet

Codon

Anticodon

Wobble

Polypeptide
Peptide bond

RNA polymerase

Sense strand

Antisense strand




Learning Experience #6

Change in Sequence, Change in Trait

Mutation

Addition (insertion)

Deletion

Substitution

Frame shift



Activity               Simple Mistake, Serious Consequences

Activity               The Error of Our DNA

                             -   DNA errors



Learning Experience #7

A Gene for Everything and Every Gene in Its Place

Complementary base pairing

Heritable

Chromosome

Replicated chromosome

Centromere

Chromatid

Supercoiled DNA
Histone

Banding pattern

Karyotype

Diploid



Activity               DNA, DNA, Wherefore Art Thou, DNA?

Activity               Characterizing Chromosomes

Activity               Reading the Future? Analyzing Chromosomes and Explaining the Consequences

                             -   Karyotype letter assessment p. 212, #7 (do peer critique prior to final copy of
                                 letter)
                             -   autosome and sex chromosomes



Learning Experience #8

Legacy of Heredity

Sexual reproduction

Asexual reproduction

Gametes

Paternal

Maternal

Mitosis

Meiosis

Oogenesis

Oocyte

Ovum

Ovary

Spermatogenesis

Spermatocyte

Sperm
Flagellum

Testis

Fertilization

Zygote

Diploid

Haploid

Genotype

Phenotype

Homologous chromosomes

Allele

Interphase

Prophase

Metaphase

Anaphase

Telophase

Cytokinesis



Reading            The Cells of Genetic Continuity

                          -   notes

Activity           Dance of the Chromosomes

                          -   Color chromosomes/chromatids to review meiosis
                          -   notes on gene, alleles, trait, variant, crossing-over

Activity           Simulating the Stages of Meiosis: Part A and Part B

Activity           The Mating Game

Activity           Mistakes of Meiosis

                          -   class notes
                          -   Video

         Reading   Cloning of the Lamb: Silence of the Man?
Learning Experience #9

In the Abbey Garden

Probability

Pistil

Stigma

Style

Ovary

Stamen

Anther

Filament

Petals

Sepals

Self-pollination/fertilization

Cross pollination/fertilization

F0/P generation

F1 generation

F2 generation

Genotype

Phenotype

Dominant

Recessive

Homozygous

Heterozygous

Principle of dominance

Principle of segregation
Principle of independent assortment

Punnett square

Dihybrid cross

Test cross



                     Teacher notes

                             -   Review Mendel

                             -   Worksheets with analysis questions




Learning Experience #10               DO NOT DO THIS LEARNING EXPERIENCE

Linked genes

Crossing over

Autosomes

Sex-linked genes



Learning Experience #11

What Mendel Never Knew

Complete dominance

Incomplete dominance

Codominance

Multiple alleles

Pleiotropic

Polygenic



                     Teacher notes

                            - Modes of inheritance, sex-linked genes and autosomes
Activity             Variation: It’s Not That Simple
                              -   notes with activity

Reading                Playing Your Hand

                              -   Homework activity

For Further Study      The Anastasia Mystery (time permitting)

Reading                The Mysterious Woman

Video                  Anastasia: Dead or Alive?

Activity               What Runs in the Family?

Reading                DNA Solves the Mystery

Experiment             Whose DNA was Left Behind

                              -   Electrophoresis experiment

Learning Experience #12

Genetics and Evolution: Making the Connection

Charles Darwin

Natural selection

Artificial selection

Acquired traits

Evolution

Selective pressure

Species

Gene pool

Allele frequency

Selective advantage

Coevolution

Differential survival and reproduction

Fitness




Activity               Antibiotic Resistance: Evolution in Action
Activity           Teddy Graham Selection

                         -   OR Breeding Bunnies activity?

Reading            Changing Genes, Changing Populations

                         -   Review 3-4 main points of Darwin’s evolution

Reading            One Good Change Deserves Another

UNIT 4: WHAT ON EARTH?

Learning Experience #1           DO NOT DO THESE LEARNING EXPERIENCES

Learning Experience #2

Learning Experience #3

Learning Experience #4

Learning Experience #5

Learning Experience #6

Variation…Adaptation…Evolution

Species

Genus

Family

Order

Class

Phylum

Kingdom

Archaebacteria

Eubacteria

Protista

Fungi

Plantae

Animalia

Taxonomy
Molecular taxonomy

Inference

Fossil record

Morphology

Homologous structures

Analogous structures

Embryology

Biogeographical data

Superposition



Activity               What Is This, Anyway?

Reading                Collectors Classify

                              -   teacher notes; include 6 kingdoms

Activity               I Came, I Saw, I Inferred

                              -   Dinosaur activity?

Reading                The Evolving Understanding of Evolution: A Second Look

                              -   PBS video clips (on-line)

Activity               The Beak of the Finch

                              -   graphing and interpreting data also

                              -   VHS on finch

Activity               Variation is the Spice of Life

                              -   individuals vs. populations

Learning Experience #7

Must Like Long Walks, Dining by Candlelight and Be of Same Species

Species

Hybridization

Darwin
Artificial selection

Vertical evolution

Branching evolution

Non-branching evolution

Divergent speciation



Activity                Of Fish and Dogs

Reading                 The Fundamental Unit

Reading                 Cichlids Past and Present (time permitting)

Learning Experience #8

The Diversity of Life

Reading                 New Species

                               -   branching and non-branching speciation

				
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