OSTEOPOROSIS University of Wisconsin NEWSLETTER Hospital and Clinics Neon K Ringwood, MS Editor Volume 7, Issue 2 April 2009 Search for Osteoporosis Genes Inside this issue: For the first time ever, G e n o m e - w i d e investigated,” he said. Gardening 2 an extensive genome- genotyping, a very “The next step will be Bears Yield 3 wide search has demanding and labor- identifying what those Bone Secret been undertaken to intensive procedure, genes are and how Bone Mineral 3 find the genes linked measures genetic they might contribute Density Testing to osteoporosis and variations called ‘Snips’, to our understanding Recipe File 4 fracture. There are within each of our of osteoporosis and 30,000 genes in the 30,000 genes,” said its prevention.” The human genome, but Garvan’s Associate discovery of genes until now few have been Professor Tuan Nguyen, linked to osteoporosis unequivocally linked to who has been involved will allow researchers osteoporosis and fragility with the Dubbo project to better develop fractures. The Garvan for almost 20 years. prognostic models, B.O.N.E.S. Institute for Medical “The collaborative study and help clinicians SUPPORT Research collaborated examined more than identify individuals with GROUP with the Icelandic 300,000 such markers high risk of fracture for genetics company, and found 12 that were intervention. will meet on deCode, in a project linked to bone mineral April 14th at that looked at 1500 density and 6 linked to Garvan Institute for Oakwood women from Garvan’s fragility fractures. Some Medical Research, Auditorium Dubbo Osteoporosis of these Snips are close www.gavan.org. 6209 Mineral Epidemiology Study to genes that are already au/news-events Point Road as well as more than known to be important (Search genotyping 12,000 women from in bone biology, while osteoporosis.) Madison Iceland and Denmark. others are yet to be 1:30-2:30 p.m. Next B.O.N.E.S. Meetings Questions? Call Tuesday, April 14 - Neil Binkley, MD - Vitamin D: New Research Findings and Their Implications 265-6410 Tuesday, May 12 - Diane Krueger, BS, CBDT - Bone Density Scans - for information. What Are They and Why Are They Important? Tuesday, June 2 (Note date change from 2nd Tuesday) - Bjoern Buehring, MD - Falls - Why Do We Fall and What Can We Do to Prevent Falling? P.T. Place: Gardening with Osteoporosis 2 By Barbara Luedke, Senior PT clude: it close to your body. If you are 1. Consider the option of contain- carrying items in a bucket, it is Summers in Wisconsin. For many er gardening or raised beds. better to evenly divide the load of us that means a limited num- 2. Use long handled tools to avoid between two buckets and carry ber of months to enjoy a variety forward bending. one in each hand. of outdoor activities, and garden- 3. Bend from your knees to reach ing is frequently at the top of the for an object on the ground. list. Individuals with osteoporosis 4. Better yet, position yourself often ask if gardening is an ac- on the ground, perhaps on your ceptable activity. The answer is hands and knees or in a side-sit- yes, as long as principles of safe ting position. This is a good op- movement are followed. The two portunity to provide weight-bear- most important precautions are to ing activities through your arms avoid forward bending and twist- and upper body! ing movements. Each of these 5. If balance or the ability to move motions produces high loads on safely from the ground to stand- the vertebral bodies, especially ing is an issue, consider using a when lifting or carrying an object. stool or a kneeler with hand sup- A combination of these two mo- ports. Just remember to keep tions creates even higher com- your back straight and bend from pressive loads on the vertebral your hips. Enjoy your summer activities. Al- bodies. Therefore, always main- 6. Always use good body me- ways remember to move safely. tain good postural alignment and chanics when shoveling, hoe- Do, but don’t overdo … a diffi- use good back protective mea- ing and raking, etc. Do not bend cult concept for persons with a sures. With gardening, you reap forward or twist. Instead, stand strong work ethic. Stop before positive benefits. One is the pride with your feet apart, and one foot you become tired so you do not and satisfaction of watching your slightly ahead of the other. Then place your muscles or bones at gardens bloom and grow. Anoth- shift your weight from foot to foot risk for injury and most of all en- er benefit is the improvement in in a rocking motion. Remember joy the bounty of your efforts – all your bone strength and general to keep your back straight. Do the beautiful flowers and healthy endurance. not perform these activities if you veggies. experience pain or discomfort. Safe gardening principles in- 7. When carrying an object, hold Gardening and Yard Work = Good Exercise Researchers at the University of Since so many people enjoy these rather as a form of leisure activity Arkansas-Fayetteville found that activities, they are more likely to that is pleasurable and rewarded gardening and yard work qualify engage in them. Further, many by blooming plants, a beautiful as weight-bearing exercise, which people do not think of gardening yard or vegetables for the table. is important for bone strength. or yard work as exercise, but http://www.healthatoz.com Peace cannot be kept by force. It can only be achieved by understanding. Albert Einstein Bears Yield Bone Secret 3 How would you like to be a bear In the search for bears’ secrets and have your bone density in- that could lead to the develop- crease while you hibernate all ment of a new drug, Donahue has winter? Why don’t bears get os- checked out the animals’ para- teoporosis? That’s what would thyroid hormones, which seemed happen if we hibernated all win- to be the key to their bone resil- ter. Seth Donahue and his col- ience. Research revealed that leagues of Michigan Tech Uni- the bears’ hypothalamus, an al- versity have studied hibernating mond-size part of the brain that black and grizzly bears and found controls a number of metabolic that their bone mineral content is and nervous system processes, maintained during hibernation. might also be part of the magic Not only that, a bear’s bones get within bear bones. Donahue and stronger and less porous as it his colleagues have modified a gets older. synthetic bear hormone and have partnered with a drug company Donahue discovered these facts to further investigate this poten- by studying bears from Michigan, tial new treatment. Virginia, Washington, and Utah, and by testing the strength of bear “We are optimistic that our new Rozell, Ned, Hibernating bears yield bones donated by hunters near version of the bear parathyroid bony secret. Alaska Dispatch 2/17/09 his lab in Houghton, Michigan. will eventually lead to a new os- He wanted find out what makes teoporosis drug for humans,” Do- bears different from humans. nahue said. Legislation Proposed to Preserve Bone Density Testing An important part of osteoporosis follow in their footsteps unless fractures, hospitalizations and prevention, diagnosis and treat- the cuts are reversed. nursing home admissions can be ment is determining an individu- reduced greatly by the increased al’s bone mineral density. DXA Osteoporosis is a preventable, utilization of DXA. is the best test available to diag- under-diagnosed and under- nose and treat osteoporosis. treated disease. Women count Multiple healthcare provider for 71% of all osteoporotic frac- groups, and the National Osteo- Medicare reimbursement for DXA tures. porosis Foundation have been bone mineral testing in the physi working to reverse this threat cian’s office has been reduced by A 2008 study by Kaiser in South- that will limit access to osteopor- approximately 50% since 2006 ern California demonstrated the sis care. The good news is that and is scheduled to be cut again cost-effectiveness of DXA test- Senator Blanche Lincoln and in 2010. The current rate of $72 ing and treatment. Increasing Senator Olympia Snowe recently is substantially below the aver- DXA testing and treatment over introduced legislation in the Sen- age cost of providng this service, a 5-year period (2002-2006) re- ate to restore reimbursement which has been estimated to sulted in a 37% reduction in hip for bone density testing in the be $134. Many physicians have fractures. The cost to the Medi- phyiscian’s office setting. been forced to discontinue provi- care budget for payment related deing this service and more will to potentially preventable hip International Society for Clinical Densi- tometry www.iscd.org University of Wisconsin Hospital and Clinics Suite100 2870 University Ave. Madison WI 53705 RECIPE FILE Hoppin’ John 1 cup cooked brown rice ½ medium green bell pepper, chopped 2 cups water 3 stalks celery, chopped 1 large clove garlic, lightly smashed 1 jalapeno pepper, chopped (optional) 1 bay leaf ½ tsp. dried thyme leaves 2 cans (15 oz.) black eyed peas, rinsed and drained ¾ tsp. ground cumin 1 medium onion chopped Salt and freshly ground black pepper, to taste 1 (14 oz,) can diced tomatoes 4 green onions, sliced 1 medium red bell pepper, chopped In a large, heavy pan, cook the rice in the water with the garlic and bay leaf for about 30 minutes, or until the rice is tender. Add the black-eyed peas, onion, tomatoes (and their juices), red and green bell peppers, celery, jalapeno pepper, thyme, cumin, salt and pepper. Cover and cook for another 10 to 20 minutes, adding an additional 1/4-cup water if necessary, until the rice is tender and the vegetables have released their liquid. Stir in the sliced green onion. Serve with hot sauce, if desired. Makes 10 servings, 1/2 cup each.
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