CURRICULUM VITAE
                              Pascal DEMOLY

Pascal DEMOLY, MD, PhD is a chest physician and allergologist at the University
Hospital of Montpellier, France. He qualified from the Montpellier School of
Medicine in 1992 and was trained in both allergy and chest medicine at the same
university, where he is Professor of Pulmonology since September 2002.

Professor Demoly is now head of the clinical department of allergology and
responsible for the allergy teaching programme of the University of
Montpellier, France. He is also actively involved in basic science,
related to the pathophysiology of drug allergy.

Professor Pascal DEMOLY is a member of various medical societies and
currently the president of the European Network for Drug Allergies, the
EAACI Interest Group of Drug Allergy. He has been an expert of various
European grants and World Health Organization initiatives : International
consensus on specific immunotherapy (1997), Allergic Rhinitis and its
Impact on Asthma (1999-current), InterAirways (2007-current).

He is at the editorial boards of some French and European journals (Allergy,
European Journal of Allergy and Clinical Immunology, Journal of Investigational
Allergology and Clinical Immunology). He has written numerous publications and
chapters of allergy, asthma and immunology and has lectured in several local and
international conferences.


1- Revues internationales à comité de lecture :
1.   Brockow K, Romano A, Blanca M, Ring J, Pichler WJ, Demoly P. General considerations for
      skin test procedures in the diagnosis of drug hypersensitivity [mise au point-consensus].
      Allergy 2002; 57: 45-51.
2.   Raison-Peyron N, Messaad D, Bousquet J, Demoly P. Selective immediate hypersensitivity to
      pidolate [cas clinique]. Allergy 2002; 57: 53-54.
3.   Gougat C, Jaffuel D, Gagliardo R, Henriquet C, Bousquet J, Demoly P, Mathieu M.
      Overexpression of the glucocorticoid receptor and ß isoforms inhibits AP-1 and NF- B
      activities hormone-independantly [article original]. Journal of Molecular Medicine 2002;
      80 : 309-318.
4.   Messaad D, Reynes J, Fabre J, Bousquet J, Demoly P. Long term safety and efficacy of
      nevirapine tolerance induction [article original]. Clinical Experimental Allergy 2002; 32 :
5.   Demoly P, Allaert FA, Lecasble M, and PRAGMA. ERASM, a pharmacoepidemiologic survey
      on management of intermittent allergic rhinitis in every day general medical practice in
      France [article original]. Allergy 2002; 57 : 546-554.
6.   Piette V, Bourret E, Bousquet J, Demoly P. Prick tests to aero-allergens : Is it possible to
      simply wipe the device between tests ? [article original]. Allergy 2002; 57 : 940-942.
7.   Demoly P, Persi L, Dhivert H, Delire M, Bousquet J. Immunotherapy with KLH-conjugated
      decapeptide vaccine in cypress pollen allergy [article original]. Clinical Experimental
      Allergy 2002; 32 : 1071-1076.
8.   Demoly P, Bousquet J. Drug allergy diagnosis work up [revue]. Allergy 2002; 57: S37-S40.
9.   Kvedariene V, Bencherioua AM, Messaad D, Godard P, Bousquet J, Demoly P. The accuracy
      of the diagnosis of suspected paracetamol (acetaminophen) hypersensitivity : results of a
      single-blinded trial [article original]. Clinical Experimental Allergy 2002; 32 : 1366-1369.
10. Demoly P, Botros HG, Rabillon J, David B, Bousquet J. Anaphylaxis to antitetanus toxoid
     serum [cas clinique]. Allergy 2002; 57: 860-861.
11. Demoly P, Crampette L, Daurès JP. National survey on the management of rhinopathies in
     asthma patientsby French pulmonologists in everyday practice [article original]. Allergy
     2003; 58 : 233-238.
12. Bousquet J, Van Cauwenberge P, Bachert C, Canonica GW, Demoly P, Durham SR, Fokkens
     W, Lockey R, Meltzer EO, Mullol J, Naclerio RM, Price D, Simons FE, Vignola AM, Warner
     JO. Requirements for medications commonly used in the treatment of allergic rhinitis
     [Consensus OMS]. Allergy 2003; 58 : 192-197.
13. Demoly P, Lebel B, Arnoux B. Allergen-induced mediator release tests [revue]. Allergy 2003;
     58 : 553-558.
14. Demoly P, Allaert FA, Lecasble M, Bousquet J; PRAGMA. Validation of the classification of
     ARIA (allergic rhinitis and its impact on asthma) [article original]. Allergy 2003; 58 : 672-675.
15. Demoly P, Piette V, Daures JP. Asthma therapy during pregnancy [revue]. Expert Opinion in
     Pharmacotherarapy 2003 ; 4: 1019-1023.
16. Milgrom H, Tran ZV, Demoly P. Towards evidence-based practice of allergy and clinical
     immunology: applying an evidence-based medicine approach to allergen avoidance
     [éditorial]. Current Opinion in Allergy and Clininical Immunology 2003; 3: 155-157
17. Raison-Peyron N, Messaad D, Bousquet J, Demoly P. Selective immediate hypersensitivity to
     clavulanic acid [cas clinique]. Annals of Pharmacotherapy 2003; 37 : 1146-1147.
18. Bousquet J, Vignola AM, Demoly P. Links between rhinitis and asthma [revue]. Allergy 2003;
     58 : 691-706.
19. Garrel R, Gardiner Q, Khudjadze M, Demoly P, Vergnes C, Makeieff M, Guerrier B, Crampette
     L. Endoscopic surgical treatment of sinonasal polyposis-medium term outcomes (mean
     follow-up of 5 years) [article original]. Rhinology 2003; 41 : 91-96.
20. Aberer W, Bircher A, Romano A, Blanca M, Campi P, Fernandez J, Brockow K, Pichler WJ,
     Demoly P. Drug provocation testing in the diagnosis of drug hypersensitivity reactions:
     general considerations [consensus]. Allergy 2003; 58 : 854-863.
21. Demoly P, Piette V, Daures JP. Treatment of allergic rhinitis during pregnancy [revue]. Drugs
     2003; 63 : 1813-1820.
22. Messaad D, Sablayrolles P, Pujol JL, Demoly P. Successful docetaxel tolerance induction [cas
     clinique]. Allergy 2003; 58 : 1320-1321.
23. Torres MJ, Blanca M, Fernandez J, Romano A, Weck A, Aberer W, Brockow K, Pichler WJ,
     Demoly P [consensus]. Diagnosis of immediate allergic reactions to beta-lactam antibiotics.
     Allergy 2003; 58: 961-72.
24. Blanca M, Torres MJ, Fernandez J, Demoly P, Romano A. Disagreement and concerns
     regarding the article recently published by Macy and Burchette in Allergy 2002;57:1151
     [Lettre]. Allergy 2004; 59: 111-2.
25. Messaad D, Sahla H, Benahmed S, Godard P, Bousquet J, Demoly P. Drug provocation tests
     in patients with a history suggesting an immediate drug hypersensitivity reaction [article
     original]. Ann Intern Med 2004; 140: 1001-6.
26. Piette V, Bousquet C, Kvedariene V, Dhivert-Donnadieu H, Crampette L, Senac JP, Bousquet
     J, Demoly P. Sinus CT scans and mediator release in nasal secretions after nasal challenge
     with cypress pollens [article original]. Allergy 2004; 59: 863-8.
27. Demoly P, Hillaire-Buys D. Classification and epidemiology of hypersensitivity drug reactions
     [revue]. Immunol Allergy Clin North Am 2004; 24: 345-356.
28. Benahmed S, Scaramuzza C, Messaad D, Sahla H, Demoly P*. The accuracy of the diagnosis
     of suspected macrolide antibiotic hypersensitivity : results of a single-blinded trial [article
     original]. Allergy 2004 ; 59 : 1130-1133.
29. Demoly P, Crestani B, Leroyer C, Magnan A, Mounedji N, Humbert M. Control and
     exacerbation of asthma: a survey of more than 3000 French physicians [article original].
     Allergy 2004; 59: 920-926.
30. Hemery ML, Dhivert-Donnadieu H, Verdier R, Dujols P, Godard P, Demoly P. A clinical and
     serological follow-up study of health care workers allergic to natural rubber latex who had
     followed a latex avoidance programme [article original]. Allergy 2004 ; 59 : 1013-1014.
31. Romano A, Blanca M, Torres MJ, Bircher A, Aberer W, Brockow K, Pichler WJ, Demoly P*.
     Diagnostic of non-immediate rections to beta-lactam antibiotics [consensus]. Allergy 2004;
     59 : 1153-1160.
32. Gomes E, Cardoso MF, Praça F, Gomes L, Marino E, Demoly P. Self-reported drug allergy in
     a general adult Portuguese population [article original]. Clin Exp Allergy 2004 ;.34 : 1597-
33. Hemery ML, Arnoux B, Dhivert-Donnadieu H, Rongier M, Barbotte E, Verdier M, Demoly P.
     Confirmation of the diagnosis of natural rubber latex allergy by the Basotest® method. [article
     original]. Int Arch Allergy Immunol 2005 ; 136 : 53-57.
34. Hemery ML, Arnoux B, Rongier M, Barbotte E, Bousquet J, Demoly P. Correlation between
     former and new assays of latex IgE specific determination using the K82 and K82
     recombinant allergens from the Pharmacia diagnosis® laboratory. [article original]. Allergy
     2005 ; 60 : 131-132.
35. Brockow K, Christiansen C, Kanny G, Clement O, Barbaud A, Bircher A, Dewachter P, Gueant
     JL, Rodriguez Gueant RM, Mouton-Faivre C, Ring J, Romano A, Sainte-Laudy J, Demoly P,
     Pichler WJ. Management of hypersensitivity reactions to iodinated contrast media.
     [consensus]. Allergy 2005 ; 60 : 150-158.
36. Demoly P, Romano A. Update on ß-lactam allergy diagnosis [revue générale]. Curr Allergy
     Asthma Reports 2005; 5: 9-14.
37. Gomes E, Pichler WJ, Demoly P, Aberer W, Frew AJ, de Weck A. The Drug Ambassador
     Project. The diversity of diagnostic procedures for drug allergy around Europe. Allergy Clin
     Immunol Intern 2005; 17: 9-18.
38. Bousquet PJ, Gallega MP, Dhivert-Donnadieu H, Demoly P. Latex is not essential in a
     standardized skin prick test battery [article original]. Allergy 2005; 60: 407.
39. Bousquet PJ, Co Minh HB, Demoly P. Isolated urticaria to ondansetron and successful
     treatment with granisetron [cas clinique]. Allergy 2005; 60: 543-4.
40. Fontaine C, Bousquet PJ, Demoly P. Anaphylactic shock caused by a selective allergy to
     celecoxib, with no allergy to rofecoxib or sulfamethoxazole. [cas clinique]. J Allergy Clin
     Immunol 2005; 115: 633-4.
41. Demoly P. Anaphylactic reactions-value of skin and provocation tests [mise au point].
     Toxicology 2005 ; 209 : 221-223.
42. Demoly P, Daurès JP. Managing asthma during pregnancy [comment]. Lancet 2005; 365:
43. Bousquet PJ, Co-Minh HB, Arnoux B, Daures JP, Demoly P. Importance of MDM and PPL
     skin testing in the diagnosis of ß-lactam allergy [article original]. J Allergy Clin Immunology
     2005; 115 : 1314-1316.
44. Demoly P, Gauchoux R, Morera P, Touron P, Daurès JP. The place of spirometry in the
     diagnosis of asthma in those suffering from allergic rhinitis: a pilot study [article original].
     Allergy 2005 ; 60 : 1089-1090.
45. Gomes ER, Demoly P. Epidemiology of hypersensitivity drug reactions [revue générale]. Curr
     Opinion Allergy Clin Immunol 2005; 5 : 309-316.
46. Benahmed S, Picot MC, Dumas F, Demoly P. Clinical history is not sufficient to diagnose drug
     hypersensitivity reactions. Diagnostic accuracy of a pharmacovigilance algorithm [article
     original]. Arch Intern Med 2005; 165 : 1500-1505.
47. Benahmed S, Picot MC, Hillaire-Buys D, Blayac JP, Dujols P, Demoly P. Comparison of
     pharmacovigilance algorithms in drug hypersensitivity reactions [article original]. Eur J Clin
     Pharmacol 2005; 61 : 537-541.
48. Demoly P, Gomes ER. Drug hypersensitivities: definition, epidemiology and risk factors [revue
     générale]. Eur Ann Allergy Clin Immunol 2005; 37 : 202-206.
49. Demoly P, Sabbah A. A special series on drug allergies [éditorial]. Eur Ann Allergy Clin
     Immunol 2005; 37 : 201.
50. Mertes PM, Laxenaire MC, Lienhart A, SFAR, Aberer W, Ring J, Pichler WJ, Demoly P for
     ENDA/EAACI. Reducing the risk of anaphylaxis during anaesthesia : guidelines for clinical
     practice. [consensus]. J Invest Allergol Clin Immunol 2005 ; 15 : 91-101.
51. Kvedariene V, Kamey S, Ryckwaert Y, Monique Rongier R, Bousquet J, Demoly P, Arnoux B.
     Diagnosis of neuromuscular blocking agent hypersensitivity reactions using cytofluorimetric
     analysis of basophils [article original]. Allergy 2006 ; 61 : 311-315.
52. Co-Minh HB, Bousquet PJ, Fontaine C, Kvedariene V, Demoly P. Systemic reactions during
     skin tests with β-lactams: a risk factor analysis [article original]. J Allergy Clin Immunol
     2006; 117 : 466-468.
53. Demoly P, Bozonnat MC, Dacosta P, Daurès JP. The diagnosis of asthma using a self-
     questionnaire in those suffering from allergic rhinitis: a pharmaco-epidemiological survey in
     everyday practice in France. Allergy 2006 ; 61 : 699-704.
54. Piette V, Daurès JP, Demoly P. Treating allergic rhinitis in pregnancy. Curr Allergy Asthma
     Rep 2006 ; 6 : 232-238.
55. Demoly P. Drug hypersensitivity - allergy passion [editorial]. Allergy 2006 ; 61 : 907-9.
56. Guglielmi L, Fontaine C, Gougat-Barbera C, Avinens O, Eliaou JF, Guglielmi P, Demoly P. IL-
     10 promoter and IL4-Rα gene polymorphisms are associated with immediate β-lactam
     allergy in atopic women [article original]. Allergy 2006; 61: 921-7.
57. Peyrière H, Breton H, Demoly P, Cociglio M, Blayac JP, Hillaire-Buys D, the Network of the
     French Pharmacovigilance Centers. The hypersensitivity: syndrom to drugs: analysis of the
      French pharmacovigilance database and review of the literature [article original]. Br J
      Dermatol 2006; 155: 422-8.
58. Guenegou A, Leynaert B, Benessiano J, Pin I, Demoly P, Neukirch F, Boczkowski J, Aubier
     M. Association of lung function decline with the heme oxygenase-1 gene promoter
     microsatellite polymorphism in a general population sample. Results from the European
     Community Respiratory Health Survey (ECRHS), France [article original. J Med Genet
     2006; 43: e43.
59. Kvedariene V, Martins P, Rouanet L, Demoly P. The diagnosis of iodinated contrast media
     hypersensitivity: results of a six year period [article original]. Clin Exp Allergy 2006 ; 36 :
60. Demoly P, Bousquet J. The relation between asthma and allergic rhinitis [comment]. Lancet
     2006; 368: 711-713.
61. Bousquet J, Demoly P. Specific immunotherapy – an optimistic future [comment]. Allergy
     2006; 61: 1155-8.
62. Pene J, Guglielmi L, Gauchat JF, Harrer N, Woisetschlager M, Boulay V, Fabre JM, Demoly
     P, Yssel H. IFN-{gamma}-Mediated Inhibition of Human IgE Synthesis by IL-21 Is Associated
     with a Polymorphism in the IL-21R Gene [article original]. J Immunol. 2006 ; 177 : 5006-13.
63. Guglielmi L, Guglielmi P, Demoly P. Drug hypersensitivity: epidemiology and risk factors
     [revue générale]. Curr Pharm Des 2006; 12:3309-3312.

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