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Diabetes

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                                                                                                                                       Lasker/Funding First
     Investment in research                                                                                                                  The medical and health

     saves lives and money                                                                                                               research policy program of the
                                                                                                                                      Mary Woodard Lasker Charitable Trust
                                                                                                                                             www.fundingfirst.org
facts about:
                                                                                                                                          www.laskerfoundation.org

     Diabetes
}    Today:
     :: Over 17 million Americans have diabetes.
                                                                                                        The Costs:
                                                                                                                         “If you think research is expensive, try disease.”
                                                                                                                                                             — Mary Lasker 1901–1994




                                                                                                        :: Diabetes consumes 25 percent of Medicare’s annual budget.
     :: About 1 million Americans are diagnosed with diabetes                                              The combined private and public cost of diabetes in the U.S.
        each year.                                                                                         was approximately $100 billion in 2000: $45 billion for direct
                                                                                                           health care costs and $55 billion for lost productivity, disability
     :: Minorities are disproportionately affected by adult-onset
                                                                                                           payments, and premature death.
        (type 2) diabetes.
                                                                                                        :: On average, it costs someone with diabetes over $10,000 a
     :: A person with diabetes is 2 to 4 times more likely to also have
                                                                                                           year for health care. That is almost 4 times more than the
        heart disease. Overall, 75 percent of people who suffer from
                                                                                                           average person pays for health care.
        diabetes will die of heart disease and/or stroke.
                                                                                                        SOURCE: CENTERS FOR DISEASE CONTROL AND PREVENTION {WWW.CDC.GOV}
     :: The rising incidence of obesity in children is an important                                     NATIONAL INSTITUTES OF HEALTH {WWW.NIH.GOV}

        factor in the epidemic of adult-onset (type 2) diabetes among
        American youth.
     SOURCES: NATIONAL CENTER FOR HEALTH STATISTICS {WWW.CDC.GOV/NCHS}
     AMERICAN DIABETES ASSOCIATION {WWW.DIABETES.ORG}                                                          survivor
     JUVENILE DIABETES RESEARCH FOUNDATION INTERNATIONAL {WWW.JDRF.ORG}


                                                                                                                  NAME:     DENISE STOKES
                                                                                                                    AGE:    36
SAVING LIVES
                                                                                                               DISEASE:     DIABETES
SAVING MONEY
                                                                                                                   TYPE:    1

     H OW R E S E A R C H S AV E S L I V E S :
     :: The National Institutes of Health (NIH)-sponsored Diabetes                                               Denise Stokes remembers the summer after the first
        Prevention Program demonstrated that the risk of developing                                            grade vividly; it was a time that changed her life forever.
        adult-onset (type 2) diabetes can be reduced by 58 percent with                                        A seven-year-old traveling home from a beach vacation
        proper exercise and diet.                                                                              with her parents, Denise remembers that she could not
                                                                                                               stop drinking soda. Soon after she was diagnosed with
     :: Kidney transplantation and dialysis improves the lives of 39,000                                       insulin-dependent (type 1) diabetes. Out of the more than
        people each year who suffer from kidney failure as a result of                                         17 million Americans with diabetes, approximately five to
        diabetes.                                                                                              ten percent are type 1.
     SOURCE: U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES {WWW.HHS.GOV/NEWS}
     AMERICAN DIABETES ASSOCIATION                                                                                Denise, now 36-years-old, has struggled since child-
                                                                                                               hood with the restrictions that diabetes put on her life.
     H OW R E S E A R C H S AV E S M O N E Y :                                                                 She has also seen how medical research has changed
                                                                                                               her life for the better. “I remember when short-acting
     :: Diabetes is the leading cause of adult blindness in the U.S.
                                                                                                               insulin came out. Before that, I could take insulin if I felt
        Research funded by NIH demonstrates that laser treatment
                                                                                                               sick, but it would take hours to work.”
        saves up to $1.6 billion a year by preventing and treating
        blindness in people with diabetes.*                                                                       After years of diminishing eyesight—a common side
     :: Captopril, a drug that controls blood pressure, delays the onset                                       effect of diabetes—Denise was facing cataract surgery.
        of kidney failure in diabetes patients. One economic model                                             She waited as long as possible to have the surgery
                                                                                                               because of the substantial risk that she could lose sight
        predicts that if 85% of people with diabetes had begun treatment
                                                                                                               in the affected eye altogether. Last year she had the
        with captopril in 1995, the direct savings in the U.S. in 2004 would
                                                                                                               surgery. It was an amazing success and she was able to
        be $475 million with cumulative cost savings of $2.4 billion.**                                        see well enough to balance her own checkbook for the
     *SOURCE: “THE BENEFITS OF MEDICAL RESEARCH AND THE ROLE OF NIH,” OFFICE OF THE CHAIRMAN,
     CONNIE MACK, JOINT ECONOMIC COMMITTEE, UNITED STATES SENATE, MAY 2000 {WWW.JEC.SENATE.GOV}
                                                                                                               first time in years.
     **SOURCE: “ACE INHIBITION IN DIABETIC PATIENTS: ECONOMIC IMPLICATIONS.” RODBY, R.A., LEWIS, E.J.
     PHARMACOECONOMICS.                                                                                          Today, Denise and her husband are raising their three
                                                                                                               children in Tennessee. Together, they keep up with diabetes
                                                                                                               research and look for the next breakthrough that might
                                                                                                               provide Denise with a better quality of life.
facts about:                 } Diabetes
     Hope for the Future:                                                              The Bottom Line:
     :: Prevention: In a study of more than 3000 people at risk for                    Today’s research is the foundation of tomorrow’s cure for
        adult-onset (type 2) diabetes, the Diabetes Prevention                         diabetes. Investing in research will provide better treat-
        Program found that the drug metformin reduced the risk of                      ments, prevent disease and disability, and ultimately, lead to
        getting type 2 diabetes by 31 percent.*                                        longer, more productive lives for more Americans.
     :: Treatment: Patient education in combination with comprehen-
        sive medical supervision can reduce the frequency of many
        complications of diabetes such as blindness, kidney failure
                                                                                         Prevalence of Diabetes by U.S. States*
        and stroke.**
     :: Cure: A clinical trial sponsored jointly by the NIH and the
        Juvenile Diabetes Research Foundation seeks to confirm pre-
        liminary studies that show pancreatic islet transplantation can
        reduce the incidence of complications resulting from diabetes
        and potentially eliminate the need for insulin injections by
        patients with type 1 diabetes.***
     *SOURCE: U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES                                                                                                        1990
     **SOURCE: CENTERS FOR DISEASE CONTROL AND PREVENTION
     ***SOURCE: JUVENILE DIABETES RESEARCH FOUNDATION INTERNATIONAL




 Eliminating Health                             Very Important
 Disparities Is                                 Somewhat Important
 Important                                      Not Very/Not At All Important
                                                Don’t Know
 Studies show that certain
 health problems such as                      1%
                                                                                                                                                                  1995
 diabetes, heart disease, and               6%
 infant mortality happen
 more often among citizens                                                      68%
 with lower incomes and                   25%
 minorities... How important
 do you feel it is to conduct
 medical or health research
 to understand and eliminate
                                           SOURCE: AGGREGATE 2002, CHARLTON RESEARCH
 these differences?                        COMPANY FOR RESEARCH!AMERICA


                                                                                                                                                                  2000




                                                      For additional information,
                                                      contact the American Diabetes                                No Data             Less than 4%

     1101 King Street                                 Association at 1-800-DIABETES;
     Suite 520                                        www.diabetes.org OR the                                               4% to 6%             Above 6%
     Alexandria, Virginia 22314                       Juvenile Diabetes Research
     703.739.2577                                     Foundation International          *Includes women with a history of gestational diabetes.
     1.800.366.CURE                                   1-800-533-CURE; www.jdrf.org.     SOURCE: MOKDAD ET AL., DIABETES CARE 2000;23:1278-83; J AM MED ASSOC 2001; 286 (10)
     Fax 703.739.2372                                                                   CDC, BEHAVIORAL RISK FACTOR SURVEILLANCE SYSTEM

     www.researchamerica.org
     info@researchamerica.org

				
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