Medical Nonfiction Hematology Medicine Anthony D Ho Rainer Haas Richard E Champlin by P-MarcelDekker

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This book integrates recent advances in molecular and cell biology of hematopoietic stem cells (HSC) with developments in clinical research in stem cell-based therapy-providing an up-to-date review of novel cytokines and cellular components; animal models; cell preparation, selection, and collection; minimal residual disease and purging; expansion of progenitor cells; allogeneic and autologous transplantation; cellular gene and immunotherapy; and more.

Examines key areas for treatment with HSC, including ambulatory care and monitoring, regimen-related toxicities, immunodeficiency and immunization, infection, chronic graft-versus-host and disease, secondary malignancies, and long-term quality of life.

Covering stem cell pool regulation and the complex interplay of extrinsic and intrinsic events, Hematopoietic Stem Cell Transplantation
summarizes current understanding and development of clinical allogeneic HSC transplantation
discusses the use of allogeneic transplantations with reduced conditioning regimen or mini-transplantation
considers various strategies for mobilization of HSCs from peripheral blood (PB) of normal donors
details detection of bone marrow contamination by tumor cells and removal procedures
focuses on efforts to increase the ex vivo transduction efficiency of human HSCs with retroviral vectors
explores the effects of growth factor administration and leukapheresis on PB stem cell donors
shows the impact of CD34+ cell isolation and the relevance of expansion of HSC from bone marrow for clinical use
reveals how minimal residue disease detection assays are crucial for tracking the clinical significance of infused tumor cells
employs automated fluorescence image cytometry to study early HSC behavior following seeding

Incorporating contributions from over 90 researchers who cite more than 2180 references to encourage continued study, Hematopoietic S

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									Hematopoietic Stem Cell Transplantation
Editor: Anthony D. Ho
Editor: Rainer Haas
Editor: Richard E. Champlin
Table of Contents

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Description

This book integrates recent advances in molecular and cell biology of hematopoietic stem cells (HSC)
with developments in clinical research in stem cell-based therapy-providing an up-to-date review of novel
cytokines and cellular components; animal models; cell preparation, selection, and collection; minimal
residual disease and purging; expansion of progenitor cells; allogeneic and autologous transplantation;
cellular gene and immunotherapy; and more.


Examines key areas for treatment with HSC, including ambulatory care and monitoring, regimen-related
toxicities, immunodeficiency and immunization, infection, chronic graft-versus-host and disease,
secondary malignancies, and long-term quality of life.


Covering stem cell pool regulation and the complex interplay of extrinsic and intrinsic events,
Hematopoietic Stem Cell Transplantation
summarizes current understanding and development of clinical allogeneic HSC transplantation
discusses the use of allogeneic transplantations with reduced conditioning regimen or mini-
transplantation
considers various strategies for mobilization of HSCs from peripheral blood (PB) of normal donors
details detection of bone marrow contamination by tumor cells and removal procedures
focuses on efforts to increase the ex vivo transduction efficiency of human HSCs with retroviral vectors
explores the effects of growth factor administration and leukapheresis on PB stem cell donors
shows the impact of CD34+ cell isolation and the relevance of expansion of HSC from bone marrow for
clinical use
reveals how minimal residue disease detection assays are crucial for tracking the clinical significance of
infused tumor cells
employs automated fluorescence image cytometry to study early HSC behavior following seeding

Incorporating contributions from over 90 researchers who cite more than 2180 references to encourage
continued study, Hematopoietic Stem Cell Transplantation is a blue-chip reference for hematologists,
hematopathologists, oncologists, cytotherapists, transplantation immunologists, and molecular
biologists.
Reviews

"...The list of authors includes more than 100 of the most prominent specialists from all over the world....

"...highly informative."



" a stimulating introduction to some of the more difficult and complex topics within the field."

								
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