THE UNIVERSITY OF NOTTINGHAM SCHOOL OF CLINICAL SCIENCES DIVISION OF ACADEMIC RADIOLOGY Job Title: Non- Clinical Lecturer in Neuroimaging/Medical Image Analysis Location: Division of Academic Radiology, Queen’s Medical Centre Contract Status: This full-time permanent post is available from 1 September 2010 and is open to job share. Salary: £32,620 - £43,840 per annum, depending on qualifications and experience (salary may progress to £50,822 per annum, subject to performance). Appointment Applications are invited from outstanding medical imaging scientists for the above post to further develop the interdisciplinary translational neuroimaging program within the Division of Academic Radiology, and the Institute of Neuroscience. The person appointed will be expected to develop a competitive program of research in neuroimaging within, or allied to, the research directions of Academic Radiology. The main research interest is to develop imaging biomarkers of CNS diseases and complex symptoms including neurodegeneration, stroke, brain cancer, and chronic pain (see: http://www.nottingham.ac.uk/SCS/Divisions/AcademicRadiology/index.aspx. Applications are particularly encouraged from those with research interest in diffusion tensor MR imaging, molecular MRI or neuropharmacological MR studies. The successful candidate will be expected to contribute to undergraduate and postgraduate teaching, student supervision, and to taught modules for the MSc in translational neuroimaging. Candidate must hold a PhD (or equivalent) in a relevant subject, have an excellent track record in high quality publications, significant independent postdoctoral research, and clear potential for international leadership in their field. It is desirable that candidates should have a track record of raising external research funding, collaboration across disciplines, experience in supervising postgraduate students, and experience of different types of assessment and higher education quality assurance. This Post Accountable to the Head of Division of Academic Radiology. This post will provide the Lecturer with an exciting and challenging opportunity to build on their own research activities, to facilitate research development within the Division of Academic Radiology, and to participate in undergraduate and postgraduate teaching. 1. Research The successful candidate will have a proven track record in initiating and undertaking original research, as indicated by excellent publications record and grant income. We wish to appoint an individual whose research activities complement the activities of the Division (See appendix 3). A major criterion in making this appointment will be the research potential of the individual as well as the area of research activity. The Lecturer will be expected to obtain research funding for PhD and Postdoctoral Staff. 2. Teaching The University of Nottingham and Nottingham University Hospitals NHS Trust (NUH) are major centres for undergraduate and postgraduate education and teaching. Involvement in the supervision and teaching of undergraduates (knowledge and clinical skills) as well as making contributions to the management of teaching including participation in assessments (question writing, standard setting, clinical skills examinations), module coordination and curriculum development. The successful candidate will also be expected to play a significant role in post- graduate teaching. Academic Radiology has started a MSc course in Translational Neuroimaging in 2009/2010. The successful candidate is expected to contribute significantly to develop and deliver taught courses for this MSc, and to supervise MSc and BMedSci students for their research projects. In addition, contribution to mentoring and supervision of students is expected. 3. Managerial and Administrative duties As a member of the Division, the appointee would assist in the development of the research programme, planning and delivery of teaching and contribute to an aspect of the Division of Academic Radiology’s administration. The Lecturer will take on a supervisory role for the information technology infrastructure for the Division. This will require close liaison with the School and University IT departments to ensure that the system specification and software remain current, and comply fully with University security policy. The Lecturer will share responsibility for the direct supervision of junior staff. The above list is not fully specific or comprehensive and the appointee may be expected to undertake other activities as required by the Head of Academic Radiology. 4. Job Plan The appointee will be expected to show excellent time management and organizational skills. As such the post does not have a fixed timetable. The appointee will spend approximately 70% of their time on academic pursuits including research and supervision of research students, 20% teaching and developing teaching materials, and 10% on administrative duties. Flexible working is permitted, but a significant presence during working hours is required to facilitate interaction with students and staff. Attendance at staff meetings and the weekly divisional journal club and research meetings is expected. 5 Requirements for the post: • A track record in research and plans for research consistent with the research strategy of the Faculty and the School of Clinical Sciences. • A higher postgraduate research degree comprising a PhD or equivalent. • The ability to work well in an academic environment, being able to combine leadership qualities with team-work. • A full commitment to undergraduate and postgraduate education. Knowledge and skills to be able to maintain and develop the Division’s information technology infrastructure. 6. Qualifications and Experience The appointee to the post must be able to: • Perform well in the Research Excellence Framework (REF). • Attract research students and research funding. • Co-supervise BSc/BMedSci, MSc and PhD students. • Publish peer-reviewed papers in appropriate high impact journals. • Teach at undergraduate and postgraduate level. • Participate in University/Faculty/School/Divisional committees and related administrative function. 7. Administrative support Office accommodation and administrative support will be provided, as will a PC with Email and Internet access. This new post will be supported by a share of University support staff. Informal enquiries may be addressed to Professor DP Auer, tel: 0115 823 1178, Email: Dorothee.Auer@Nottingham.ac.uk. Please note that applications sent directly to this Email address will not be accepted. Person Specification: Requirement Essential Desirable Qualifications Undergraduate degree in physics, computer science, neuroscience, mathematics or other relevant scientific degree (or equivalent). PhD (with a significant component involving analysis of medical images). Medical Significant research experience with Experience of applying image imaging demonstrable independent research output. analysis techniques in a clinically- experience Expertise in the field of MRI-based image based research setting. analysis with experience of statistical analysis Experience in the of images. assessment/analysis of quality Excellent knowledge of MR image acquisition control for imaging data. and analysis. Deep understanding of MR physics. Excellent programming skills. Advanced practical knowledge of major image analysis packages. Managerial Experience of management of resources, Experience of obtaining research experience including personnel. ethics committee approval and R&D Ability to foster good working relationships approval for research projects. within the research team, both clinical and Experience of business planning. non-clinical. Ability to form effective collaborations with researchers in other academic departments. Understanding of research governance and subject confidentiality issues. Sound knowledge of safety issues in the MRI scanner environment. Teaching, Ability to train and supervise junior members Experience in module preparation, training and of the research team. supervision and assessment at a supervision Ability to teach other students and staff post-graduate level. experience outside the research team at undergraduate Teaching diploma or other evidence and post-graduate levels. of training in teaching skills. Experience of lecturing and demonstrating techniques to students. Experience of supervising or co-supervising undergraduate research projects. Research and Proven track record of research in the field of PI on grants held with research publications MRI-based medical image analysis. council, in the field of medical image Demonstrable output of independent and analysis. innovative research. Principal or co-applicant on research A clear potential for developing and grants. implementing novel image analysis techniques and projects. Authorship of peer reviewed publications in leading journals in the field of medical imaging. Professional Clear evidence of continuing professional Member of, and contributor to, the development. relevant learned societies. Personal An aspiration to deliver research excellence. Evidence of having received attributes Strong ability to cooperate in a multi- professional training in disciplinary team. communication skills and person Excellent communication skills both verbal management. and written. Ability and enthusiasm to drive innovative research projects in the field of medical image analysis. Other Presentation skills. Computer skills: data input, word processing, email. Proven reliable attendance record. Please quote ref. VF/34190. Appendix 1: Faculty of Medicine and Health Services and the School of Clinical Sciences UNIVERSITY OF NOTTINGHAM MEDICAL SCHOOL Nottingham has a strong reputation for clinical medicine, research and teaching. As one of the most popular medical schools in the country it is able to select excellent students and produce and attract good junior doctors. There is a strong commitment to develop and expand our research strengths. There are excellent facilities to support current research interests. The Faculty of Medicine and Health Services is organized into eight academic schools, namely Biology, Biomedical Sciences, Clinical Sciences, Community Health Sciences, Graduate Entry Medicine and Health, Molecular Medical Sciences, Nursing, Midwifery & Physiotherapy and Veterinary Medicine & Science. RESEARCH Research within the Faculty is undertaken by staff and research groups within individual schools and is overseen by the Faculty Research Strategy Group, which is responsible for the overall strategic direction of research, coordination of faculty wide initiatives and implementation of University wide initiatives. Within the faculty are a number of flagship clinical translational priority groups, such as the NIHR funded Biomedical Research Units (BRUs) in respiratory disease, gastrointestinal disease and hearing research, NIHR funded Collaborative Leadership in Applied Health Research and Care (CLAHRC) in Mental Health, ARC/Nottingham pain centre, Tobacco Control Studies. These and other translational areas and preclinical research areas are supported by faculty wide research platforms, covering areas such as deep sequencing, screening, human physiology and clinical research facility, MR imaging, animal imaging and clinical trials unit. These faculty platforms underpin basic research technologies within the Faculty emphasing multidisciplinary use. In partnership with the Nottingham Universities Hospital Trust and Nottinghamshire Healthcare Trust, the Faculty has been successful in establishing the 3 NIHR-funded BRUs a CLAHRC in Mental Health which together have resulted in around £26m of additional NIHR funding coming to the Trust/University partnerships. The University has also recently been successful in major bids to develop an academic translational imaging unit and to set up the ARC/Nottingham Pain Centre. The Faculty is a strong supporter of collaborative research, and our internationally-leading research groups have many national and international collaborations. We also actively encourage collaborations between workers in different Schools within the Faculty, particularly between basic scientists and clinicians. Increasingly we are also collaborating with researchers in other Faculties, and this has been particularly encouraged by recent strategic reviews. Particular fields of national eminence within the Faculty of Science and Engineering include biosciences, chemistry, mathematics, physics, engineering and pharmacy. The Faculty of Medicine and Health Sciences is consistenly successful in raising research funding. It generated research income of nearly £30m last year and obtained grants of more than £30m from the Research Councils and Wellcome Trust over the last three years. There has also been a major upgrade of laboratory facilities on all sites. TEACHING Student teaching began in 1970 with an initial intake of 48 students a years, rising progressively to 253 students last year. More recently the Faculty has established a graduate entry programme at Derby which is now in its fifth year and admits around 90 students. Undergraduate clinical teaching takes place at various hospitals in Nottingham. The responsibility for teaching within the Faculty lies with the Curriculum Policy Group which reports to Faculty Board. Course Management Committees responsible for individual attachments report to the Curriculum Committees. NOTTINGHAM UNIVERSITY HOSPITALS NHS TRUST Nottingham University Hospitals NHS Trust (NUH) came into being on 1 April 2006 when the two 3* rated Hospital Trusts in Nottingham became one. It is one of the largest hospital Trusts in the UK with an annual budget of more than £500 million, a total of 2,200 hospital beds across both campuses and over 11,500 staff and is currently in the process of applying for Foundation Trust status. NUH (a major teaching Trust) enjoys close links with the region’s universities and attracts and develops the highest calibre of staff. The work being carried out by NUH researchers has led to a reputation for excellence and is making a very real difference to people’s lives. The Trust continues to attract and encourage investment and remains at the forefront of research with about 700 active research projects and combined Research and Development funding of around £9m from the Department of Health. As part of a national clinical research collaboration, the Trust is a UK co-ordinating centre for clinical trials in stroke and stroke rehabilitation. It houses a training centre in breast screening and has recognised strengths in respiratory medicine and gastrointestinal disease, and major research interests in Magnetic Resonance (MR) imaging, premature babies, dermatology, neurology, oncology, clinical haematology, rheumatology, diabetes and urology. NUH is also a cancer centre – a major element of the Mid-Trent Cancer Network. SCHOOL OF CLINICAL SCIENCES The School of Clinical Sciences was formed on 1st October 2008 from individuals previously in the Schools of Human Development and Medical & Surgical Sciences and includes all hospital-based medical and surgical disciplines. The research interests of the School are therefore diverse and include Inflammatory Disease; Vascular Disease; Digestive Diseases; Surgery; Fertilisation and Embryonic Development; Development through fetal life into the newborn period and further into childhood; Neurology; Radiology and Dermatology. The School is home to NURTURE, one of the UK's leading infertility units and hosts the biggest clinically-based gastrointestinal research grouping in the UK. We are a large and dynamic school employing nearly 400 staff, principally in the Queen’s Medical Centre and City Hospital Nottingham Campuses but also at King’s Meadow Campus and the University Campus in the Centre for Biomolecular Sciences. About 70 of our staff are at Associate Professor grade or above and more than 50 of these are clinicians. Our Mission Statement is; 1. To deliver internationally-competitive research. In particular, to concentrate on research which will make a real difference to patients in the short and longer terms. 2. To provide innovative and inspiring professional teaching to undergraduate medical students, masters students and trainee researchers working towards degrees of DM and PhD. 3. To deliver cutting edge patient care in association with our NHS colleagues. The School supports basic, translational and clinical research and works closely with the NHS, particularly the Nottingham University Hospital NHS Trust. We focus on areas of excellence where we are nationally or internationally leading. These include our three National Institute for Health Research-funded Biomedical Research Units in GI and Liver Disease, Respiratory Disease and Hearing. Nottingham is the only University/NHS Trust Partnership in the UK to host three of these prestigious national units for patient-based translational research. We have also recently been funded by the Arthritis Research Campaign as their National Pain Centre. As well as cutting edge translational research at the interface between science and medicine, we have world-leading research programmes in basic science and run large, influential clinical trials. Strengths within the School include, but are not limited to: assisted reproduction, bioimaging, clinical trials, effects of early life environment on development and disease; stem cell science, infection; genetics; respiratory diseases; gastroenterology and hepatology; hearing; stroke medicine; arthritis and pain; pre-clinical cancer studies;; We teach medical students undertaking the clinical components of their professional training and pride ourselves on our innovative student-centred clinical training. We also run internationally-acclaimed masters courses in stem cell technology, sport and exercise medicine, assisted reproductive technology and translational neuroimaging. Some of our strongest recent innovations are in research training for PhD and MD degrees. We have recently established the N-Trans DTC (The Nottingham Translational Research Doctoral Training Centre). This programme, for both clinicians and basic scientists, contains taught modules in all aspects of modern translational research training alongside opportunities to perform original research in any one of our leading units, including our NIHR Biomedical Research Units. It complements other excellent PhD training within the School. Our next aim is to establish a similar programme for Clinical Trial Research training Most of our Schools’ Senior Researchers and Teachers are also clinicians who dedicate 50% of their time to patient care within the Nottingham University Hospitals NHS Trust. This close juxtaposition brings cutting-edge clinical care to our patients and clinical relevance to our research and teaching. We are closely integrated with our full time NHS clinical colleagues, many of whom are themselves leaders in research and teaching and who work closely with the School. We are working to further increase the mutual benefit from integration between the University and NHS. Appendix 2: Academic Radiology The Division of Academic Radiology is part of School of Clinical Sciences. The Division of Academic Radiology has established an international reputation in translational and clinical neuroimaging research. It has major interests in development and qualification of biomarkers for common brain diseases (neurodegeneration, stroke, mental disorders, multiple sclerosis and gliomas). The research is funded by National Institute of Health Research, Department of Health, Medical Research Council, research charities and the EU. Divisional office space and a seminar room with modern audio-visual and IT equipment is based at NUH, Queen’s Medical Campus, and the Lecturer will be based there. QMC also hosts other University Departments, the office of the Faculty of Medicine, and lecture theatres. There is access to the NUH PACS and CRIS system. Academic Radiology has dedicated research access to the clinical MRI scanners at NUH including a modern 3T MR scanner allowing for MRI research in children and acutely ill patients. In addition, there is access to the unique MR scanning facilities at the UoN for research in healthy volunteers and ambulatory patients. Staff of Academic Radiology Professor DP Auer Head of Division Dr RA Dineen Clinical Associate Professor This post – vacant Lecturer/non clinical Dr MI Schubert Lecturer (clinical) Advertised Research Radiographer Advertised Part-time Academic Clinical Lecturer Sharon Forman Research Co-ordinator and PA to Professor Auer There are three fixed-term non clinical vacancies at postdoctoral level. The division hosts an academic training programme with currently 3 academic clinical fellows in post (Years 1, 2 and 3). There is an active postgraduate training programme with currently 10 postgraduate students (9 PhD and 1 MD students) in Academic Radiology and a further 3 PhD students from other Schools are co- supervised by AR researchers. Research Interests of existing staff The main research interests of the department are as follows:- • Stroke/TIA – Neuroimaging markers to predict risk of recurrent stroke/ outcome • Neurodegeneration – Early disease markers and improved radio-pathological correlation • Neuroimaging of Pain - to understand mechanisms of pain/ pain relief in osteoarthritis • Brain Cancer – to predict tumour growth and infiltration/ to assess chemotherapy • Mental health – Neurobiological basis, Neuroimaging of drug effects/ stress effects Academic Radiology is a member of newly formed Arthritis Research Campaign National Pain Centre and has close research links with a national multi-centre Cancer Imaging Research Programme, and locally with scientists both within and outside the School of Clinical Sciences, in particular the Institute of Neurosciences and the Sir Peter Mansfield MR Centre. Appendix 3: Institute of Neuroscience Institute of Neuroscience In 2003 the University of Nottingham established the Institute of Neuroscience (IoN, co-directors Professors Stephen Jackson and Philip Bath) with the objective of promoting and developing the University’s established strengths in basic and clinical neuroscience. The IoN brings together a critical mass of more than 100 researchers to undertake high quality preclinical, translational and clinical research. To facilitate and foster transdisciplinary research, the IoN is divided into four sections, and the person appointed is expected to contribute in particular to the Neuroimaging section. For further information see http://www.nottingham.ac.uk/neuroscience. The UoN has invested in excellent facilities for translational imaging and in particular neuroimaging, with whole-body MRI scanners operating at 0.1 T, 1.5 T (two scanners, one of which is located in a clinical research unit based on the University Hospital campus), 3 T and 7T (the only 7T available in the UK, funded chiefly by the Wellcome trust). These scanners are all dedicated to research, providing ample access at reasonable scanning costs. Also available are animal scanners operating at 7T and 2.35 T, an NMR microscope operating at 9.4T, bench top NMR systems, and an experimental 3T scanner used for novel hardware developments. To support these NMR facilities the UoN also has a number of experimental and commercial hyperpolarization systems, including one to be based in the clinical research unit. Complementary to these NMR facilities are an MEG scanner, several MRI compatible EEG systems and other MRI related infrastructure, including a number of computing clusters.