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                                                                                    Cleveland, OH 44195
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Press Release
Molly Johnson 216.444.1815, (Medical Innovation Summit)
Erinne Dyer, 216.445.6472, (Heart Failure Summit)

                               MEDICAL INNOVATION
        National Speakers and Panelists to Discuss Trends, Trials, and Innovation
                  in Cardiovascular Medicine at Upcoming Conferences

[Editor’s Note: Members of the media are invited to attend both conferences. Please see
contact numbers listed above for more information.]

Sept. 25, 2007, Cleveland: Cleveland Clinic is hosting two upcoming Summits that will focus on
medical innovation and emerging trends in cardiovascular medicine.

        Oct. 1-3: Innovation is driving the development of new therapies, treatments and devices to treat
         cardiovascular disease. The 5th annual Cleveland Clinic Medical Innovation Summit will
         examine trends in medical innovation and cardiovascular technologies. The Innovation Summit is
         an international gathering of health care, business and media leaders and other decision-makers to
         dissect advances revolutionizing health care and how to accelerate the application of life-saving
         medical technologies. Also featured will be the Cleveland Clinic's annual selection of the "Top
         10" health care innovations, live, interactive surgeries and in-depth debates on industry
         challenges. For more information on the Medical Innovation Summit, including the agenda,
         please visit

        Oct. 18-20: Cleveland Clinic Kaufman Center for Heart Failure, in cooperation with the
         American Association for Thoracic Surgery (AATS) and the American College of Cardiology
         Foundation (ACCF), will present an advanced review of emerging medical and surgical
         treatments of heart failure. The Summit, called the 21st Century Treatment of Heart Failure, will
         feature presentations by leading names in cardiovascular medicine and cardiac surgery. Topics
         will include: new therapies to reverse remodeling; drugs, genes, and cellular targets; the newest
         assist devices, with an update on the total artificial heart and rotary pumps; the latest treatment
         guidelines; and breakthrough findings on the epidemiology of systolic and diastolic heart failure.

The Summits will feature internationally recognized speakers and offer unparalleled insight into the
driving forces in the world of medical innovation. Each will explore in detail, the blurring of traditional
boundaries between medical industry segments and clinical specialties that is driving increased market
consolidation, the emergence of new business models and the evolution of imaginative forms of

CCF Innovations, the technology commercialization arm of Cleveland Clinic, organizes the Medical
Innovation Summit and stewards the Clinic’s technology innovation strategy. It enhances product-
oriented innovation throughout Cleveland Clinic and transforms promising therapies, devices and
diagnostics into beneficial medical products, via spin-off companies, licensees and equity partnerships.

The Kaufman Center for Heart Failure facilitates Cleveland Clinic’s participation in national and
international clinical trials of investigational treatments and more aggressive or innovative uses of
standard heart failure therapies. Cardiologists, cardiac surgeons and researchers collaborate on early
diagnosis of congestive heart failure and more aggressive use of therapies to prevent myocardial damage.
Cleveland Clinic Heart & Vascular Institute is the recognized world leader in diagnosis and treatment of
cardiovascular disease. Cleveland Clinic has been ranked No. 1 in the nation for cardiac care by U.S.
News & World Report every year since 1995.

Cleveland Clinic, located in Cleveland, Ohio, is a not-for-profit multispecialty academic medical center
that integrates clinical and hospital care with research and education. Cleveland Clinic was founded in
1921 by four renowned physicians with a vision of providing outstanding patient care based upon the
principles of cooperation, compassion and innovation. U.S. News & World Report consistently names
Cleveland Clinic as one of the nation’s best hospitals in its annual “America’s Best Hospitals” survey.
Approximately 1,500 full-time salaried physicians at Cleveland Clinic and Cleveland Clinic Florida
represent more than 100 medical specialties and subspecialties. In 2005, there were 2.9 million outpatient
visits to Cleveland Clinic. Patients came for treatment from every state and from more than 80 countries.
There were nearly 54,000 hospital admissions to Cleveland Clinic in 2005. Cleveland Clinic’s Web site
address is