Guidence By- Presented By-
Mr. G.K. Jana Pushpendra Ku. Tiwari
Asst. prof. M.Pharma 1st sem.
(Dept. of pharmacognosy) (Pharmacognosy)
The Pharmacy and Therapeutics (P & T)
Committee is an important medical staff
advisory group. As the primary, formal
communication link between the pharmacy
and medical staff, the P & T Committee is of
particular importance to the department of
Definition: A multi-disciplinary committee
that advises medical staff and hospital
administration on matters relating to the
therapeutic use of drugs.
Purpose: to ensure that medications are used
safely and appropriately within an institution.
Organizational line of communication between
medical staff and pharmacy
Respected member of medical staff
Familiar with and advocate for progressive pharmacy
Effectiveally for pharmacy with medical staff and
Director of Pharmacy
Sets agenda with chairperson
Distributed 1 week prior to meeting
Reminder and time to review
Focus on multidisciplinary issues
Contains drug monographs, adverse drug reaction
reports, and policy changes
PTC IN DRUG SAFETY
The following checklist developed by the PTC is a great help
to ensure the adequate safety factors:
Well qualified staff , at least B.Pharm degree holder as “chief
pharmacist” & rest are diploma holders.
In hospital, has it storage facilities, properly equipped & space
Is there regulation of dengerous drugs?
How are the poision & non-poision drugs separeted?
Is there manufacturing? If yes, does it follow cGMP.
Is there physical varification of drugs for expired or detoriated
ROLE OF PTC IN ADR
Since drug therapy becoming complex, these
is increasing incidence of ADR case. The
problem is to be handle at two levels:
1. How to prevent the ADR.
2. Once they occurred how to treat them.
The PTC develops a reporting system for this
Name of drugs
Routs of administration
Date of starting & ending treatment.
Indication-for which drug were used
Adverse reaction noted for them.
Steps taken to treat these.
ROLE OF PTC IN
The certain emergency drugs must be handle at the
The PTC makes the list of such drugs & supplies to
prepare an emergency box or kit, and placed in
Emergency box contains-
• Different type syringes.
• Saline for injection
• Water for injection etc….
The list are constantly reviewed by the PTC.
Advisory capasity to medical staff and hospital administration.
Develops a formulary of drugs accepted for use in the
Established a plan suitable education programs for the hospital
professions staff on matter related to drug use.
Study problems related to drugs distribution & administration
Makes the hospitals own formulary & periodically updates it.
Prepare a list of emergency drugs to be kept in a kit in each
PTC is back bone of hospital pharmacy and
renders a great services to make the hospital
Paradkar Dr.A.R.,Chunawala, hospital and clinical
pharmacy, nirali prakashan, new delhi, page 108-
Kohli kanchan, jain s.k., hospital and clinical
pharmacy, piyush publication, delhi, page 47-50.
Sampath k. , hospital & clinical pharmacy, vikash
publication pvt. Ltd., page 60-65.
Khar, nanda, hospital & clinical pharmacy, birla