BRISTOL UNIVERSITY

                             LOCAL SAFETY RULES


DSA/DRPS                          G Young 11442
                                  D. Martin 12307/12308

Administrators                    K. Williams     11429
                                  Ian Rogers      12266

Chemical Hazard or Spill          DSA 11442
                                  or A.MacQuiban 89080

COSSH matters                     DSA 11442
                                  or A.MacQuiban 89080

Electrical matters                D. Carr 12303 or R. Norris 88784

Fire, Ambulance & Police          Security emergency No. 112233, Ambulance on external
                                  999 and then 112233

Lift failure/locked in building   Security Office 112233

Manual lifting assessment         DSA 11442/12307 or Health & Safety Office 88780

Radiation matters                 DRPS 11442/12307 or S.Liddle / T.Butterworth 88323

Any serious emergency             112233

Reporting intruders               Porter‟s Lodge 11568 (Medical School)
                                  Porter‟s Lodge 11589 (Teaching laboratories)
                                  Security 87848

Suspicious packages               Security control 87848 or 287848 External

VDU & Risk assessments            DSA 11442/12307

Genetic Modification working      DSA 11442/12307 or S.Golding 88783

Department of Physiology & Pharmacology Safety

                   Safety Committee

               Health & Safety Office

              Professor Clive Orchard
                Head of Department

              Professor Peter Roberts
              Dept. Head of Department

            Departmental Safety Advisers
                   Gareth Young
                   Debbie Martin

            Union Safety Representatives
                   Debbie Martin
                     Debi Ford

               Principle Investigators

              Individual Departmental


a.   Head of Department (HOD) Prof Clive Orchard Tel:12228/12280/12278

 ‘The provision of a healthy, safe working environment, and the conduct of risk assessments
to preserve that environment, is the responsibility of each Head of Department or other
administrative unit, acting through designated Departmental Safety Advisers where such
an appointment has been made. The Head of Department is also responsible for health &
safety during activities organised by the Department outside its own accommodation.’

Extracted from the University of Bristol Safety Policy Statement

b.   Departmental Safety Advisors (DSA) Gareth Young Tel 11442
                                             Debbie Martin Tel 12307/12308
     Responsible for:
    Advising the HOD in all matters concerning health and safety.
    Producing local safety rules through the HOD.
    Carrying out periodic internal health and safety inspections and reporting results in
     writing to the HOD.
    Providing advice on safe working practices and ensuring compliance with University
     Codes of Practice.
    Internal accident investigation and reporting of details to the Safety Office.
    Acting as liaison for Trade Union Safety Representatives.
    Acting as liaison between Works and Buildings and the Department for any work
     services within the Department.
    Liaison between the Department and the Safety Office.

c.   Managers, Superintendents and Supervisors

  Responsible for:
 Consulting with employees (within their identified functions of management) on all
  matters relating to health and safety and for bringing to the attention of the DSA or HOD
  any matter that they are unable to deal with.
 To ensure that safety and health factors are fully taken into account when organising
  systems of work within the Department.
 For ensuring that employees understand the University health and safety policy and the
  associated rules relating to their work.

d.   Individual Responsibilities

   Responsible for:
  Section 7 “Health and Safety at Work Act 1974”
   To take reasonable care for the health and safety of themselves and of other persons who
may be affected by their acts or omissions at work.
To co-operate with management to enable the employer to carry out his legal duties or any
requirements as may be imposed.
  Section 8 “Health and Safety at Work Act 1974”
  Not to intentionally or recklessly interfere with or misuse any item provided in the
   interests of health, safety and welfare.



11. C.O.S.H.H.


DECLARATIONS x2 (to be signed and one returned to Safety Advisors)

HEALTH SURVEILLANCE QUESTIONNAIRE (to be completed and returned to the
Safety Advisors)


A two-page document „Security within the Medical School‟ is available in the Dept. Office .

1. On entering the department using the card access system,

a) DO NOT allow other people to gain access with you, and
b) equally important, on leaving the building, DO NOT allow intruders to gain egress
   with you.

2. If you see someone acting suspiciously inside the department (or outside of the Medical
School), question their business and if dissatisfied, inform either the Dept. Administrator
(ext.11429), the Porters Lodge (ext.11568), or the Security Office (ext.87848).

3. If you wish to alert the security office, when you are under duress from a perpetrator,
whilst gaining entrance via the card access system, press a ZERO infront of the first 3 digits
of your PIN number.
4. LEVEL OF SECURITY. Coloured discs are on display in stairwell 1, inside door 1,
informing everyone of the level of security/ alert inside the Medical School.

BLUE            =        Daily routine
AMBER           =        There is a problem, therefore increased security
RED             =        Top level security.

Everyone should carry some form of I.D., e.g. Students Union card/ Card Access System
card. If you are seen acting suspiciously, or purely as a routine check, you may be asked for
proof of identity inside or outside of the building.

5. If you find yourself locked inside the building, ring ext.87848.


1. Operate the nearest fire alarm point(they are located in the corridors and stair wells of the

2. Ensure that the Fire Brigade is called by dialling ext.112233, or external 999 on a British
Telecom telephone. State the address of the fire, i.e. Department of Physiology &
Pharmacology, The Medical School / Teaching Laboratories Building, Bristol University.

3. Inform the Head of Department, his secretary or the Technical Managers, if possible.

4. Attempt to extinguish the fire with the nearest suitable fire appliance only if you feel
competent to do so. All fire extinguishers are kept in the main corrodors and all new fire
extinguishers are not colour coded(the type is written on them). DO NOT attempt to control
the fire if it has reached such proportions as to endanger life or escape. The prime objective
of the fire extinguishers is to facilitate escape from the building.

TYPE OF FIRE                                        WATER         CO2,extinguisher
Paper, wood, cloth, etc.,                           YES           Small fires only
Solvents, petrol, oil, paints, etc.,                NO            YES
Live electrical fire                                NO            YES

MARKING) portable fire extinguishers and wall mounted fire blankets can be located
throughout the department.
Please note. All new fire extinguishers are RED with either a Black C02 sign or Red
water sign.

1. Introduction

   The new system comprises ceiling or roof void detectors which signal smoke or heat
   changes and new manual call points with break glasses.

   The sensors monitor themselves for levels of contamination and will issue a warning
   signal to the control panel in the porters lodge before they create a false alarm; the
   period of this warning depends on the rate of contamination and can range from less
   than 1 second to several months. When the sensors are in normal sense mode an
   intermittent red light will flash every 15-20 seconds around the sensor base; the light
   will change to a continuous red light if the sensor becomes activated by smoke, heat
   or dust.

2. Departmental Responsibilities

         The Department responsible for each level must nominate floor wardens
          whose job it is to ensure that in the event of an alarm, occupants evacuate as
          quickly as possible and all rooms are checked by wardens as they leave.
          Names of wardens should be notified to the School of Medical Sciences
          Administrative Office.

         Teachers should be aware of the evacuation routes/procedures and in the first
          week of the academic year should inform students

3. Activation of evacuation sirens

   a)     Delayed siren activation
          During the period 08.00 – 18.00, Monday – Friday, activation of a sensor
          will signal on the panel in the porters lodge and unless the signal is over-
          ridden, within 5 minutes, all the sirens will sound and the building must be

          If a staff member knows that they may have activated a sensor
          accidentally, they must immediately telephone the porters lodge on a
          dedicated fire line (Tel: 11568) to enable the porters to cancel the alarm.

          In this 5-minute delay period it is imperative that it be established whether
          the sensor signal is from a false alarm. To this end the following procedures
          must be followed:
          (i)     A porter will telephone staff in the vicinity of the sensor signal to ask
                  them to check whether the alarm is real or false.
          (ii)    Simultaneously another porter will go to the sensor activation area (in
                  case people cannot be contacted by telephone).
          b)     Siren activation without delay
                 Evacuation sirens will sound immediately under the following circumstances,
                 causing immediate evacuation
                          If a break glass call point is activated
                          If two sensors sense smoke/heat/dust.
                          If a single sensor is activated when the porters lodge is not manned
                           i.e. 18.00 – 08.00 Monday-Friday, 00.00 – 24.00 Saturday and

4.   Evacuation procedures for School of Medical Sciences

                If the sirens sound continually the whole building must be evacuated via the
                 nearest exit.
                Exit via card-controlled doors is by swipe card or using a break glass facility
                 adjacent to door.
                The Head/Deputy Porter or the Administrator will use a megaphone to direct
                 evacuees towards the evacuation area. He/she will remain at the main front
                 entrance to await the Fire Brigade.
                Evacuees must assemble in the quadrangle between the Royal Fort House
                 and Physics and not wait in the road outside the Medical School.

                                               PHY SICS

         BETWEEN PHYSICS AND                                        GATEHOUSE
         ROYAL FORT/STUART                  ROYAL FORT


                                        MEDICAL SCHOOL

         Departmental floor wardens, after checking the sectors for which they are
          responsible should proceed together with departmental safety advisers and
          superintendents to the porters lodge, Royal Fort House, as this will act as an incident
          „room‟ in case Health and Safety or Security require local information about areas of
          the Medical School.
         Teachers are responsible for the safe evacuation of students from teaching
          laboratories, theatres and tutorial rooms.
         Lecturers in the main theatres 1.4 and E29 must ensure that students leave the
          theatres by the back entrances as well as the main front entrance to avoid congestion.
          Students from theatre 1.4 should proceed up St.Michael‟s Hill and not use the steps
          at the side of the Medical School.

5.        Re-entry

          The only person who has authority to cancel the alarm is the Fire Chief, the Health
          and Safety Officer or the Security Officer or their nominated representative.
          You must only re-enter after clear instructions that the building is safe. Please have
          your university ID card ready for checking and do not allow „tailgating‟ through
          card-controlled doors.

6.        Procedures to stop unnecessary false alarms

             Special sensors have been fitted (after discussion with departmental
              superintendents) to sense smoke, heat or dust in particular rooms. If there is a
              significant change in room usage it is essential to check, prior to the new use,
              that the sensor(s) will not be set off by the new activities.

             Sensors could also be set off by building work or work carried out by service
              engineers. It is absolutely ESSENTIAL that all such activities are known to your
              local superintendent well before the work/service visit to stop unnecessary false

                        (EAST WING OF CHEMISTRY)

          A separate evacuation procedure is set out for this area

          The Department responsible for each level shall nominate floor wardens whose job it
          is to ensure that in the event of an alarm, occupants evacuate as quickly as possible
          and all rooms are checked by wardens as they leave. Names of wardens should be
          notified to the School of Medical Sciences Administrative Office.

          Teaching Laboratories Fire Wardens

          Level 5

          First Year Biochemistry lab.                  Alan Hillier

          Second Year Biochemistry lab.                 Nigel Bigg

          Level 4

          Pharmacology lab.                             Gareth Young
                                                        Alex Harris
      Level 3

      Physiology lab.                               Dave Gee

      Level 2

      Histology lab.                                Debbie Martin
                                                    Debi Ford

      Medical School Fire Wardens

      C and D Floors                                Mr. K. Williams
      E Floor                                       Mr. I Rogers
      F Floor                                       Mr. R Sherwood
      CRL                                           Mrs L Sage

              Lecturers should be aware of the evacuation routes/procedures and in the first
           week of the academic year should inform students.
              On the map below the route for evacuation is shown as out onto the
           Chemistry patio and then up to the Assembly Point which is on the steps
           between the Queens Building and the School of Medical Sciences, leading to
           University Walk. Do not go into University Walk (in case the Medical School is
           also being evacuated and University Walk has to be kept clear for fire engines).
              No one should re-enter the teaching laboratories until the alarms have ceased
           and floor wardens have been told it is safe to do so by a representative from
           Chemistry, the Department which has overall responsibility for emergency
           procedures in the East Wing

                                                                      ASSEMBLY POINT ON
                                                                      WIDE STEPS BETWEEN
                                                                      QUEENS AND MED.

Collect keys and belongings ONLY if you are in your laboratory/ office. You may not be
allowed re-entry into the building for some time. DO NOT go back for your belongings if
you are elsewhere.
Departmental floor wardens, after checking the sectors for which they are responsible
should proceed together with departmental safety advisers to the bottom of indecision steps
and wait for any update from the chemistery porters lodge.


1.   DO NOT make excessive noise in the corridors
2.   DO NOT rush or panic
3.   DO NOT attempt to pass other people
4.   DO NOT use the lift.

N.B. APART FROM FIRE PRECAUTIONS, there are other times when the building has to
be evacuated, e.g. bomb scare; under these circumstances re-entry may not be possible for
many hours.


When trapped inside a lift, raise the alarm by either pressing the alarm button inside the lift,
or by dialling ext.87848 (Security Office) on the telephone provided.


The First Aiders (FA)/ Appointed Persons(AP) in the Physiology & Pharmacology
Department are;

NAME                           ROOM                                          PHONE No
A. HARRIS    (FA)              4.14, Teaching Laboratory, SMSTL              11442
C. THOMPKINS (AP)              4.14, Teaching Laboratory, SMSTL              11442
L. NICOLAS   (AP)              Department Office                             87613
G. PARKER    (AP)              Department Office                             87613
D. FORD      (FA)              2.2 & 3.3, Teaching Laboratory, SMSTL         12307/12308
D. MARTIN    (FA)              2.2 & 3.3, Teaching Laboratory, SMSTL         12307/12308
R. SHERWOOD (FA)               D2, School of Medical Sciences                11469
L. ARBERRY    (FA)             CRL                                           12295
M. MACLANE (FA)                F41                                           12291
C. LISTER-HUCKLE (FA)          F22                                           12209

The Designated First Aid Room for the Medical School is E40 - the key can be obtained
from the Porters / Angela wells in CMM.

Departmental First Aid boxes, containing bandages, wound dressings, sterile eye pads,
safety pins and plasters, are located;

 Room                            Room Location
                                 Histology Teaching lab.
 T.L. 2.2                        podium
 T.L. 2.17                       Histology Teaching lab. office
 T.L. 3.1                        Electronics work shop
 T.L. 3.3                        Histology Prep. Room
 T.L. 3.10                       Physiology Teaching lab
T.L. 4.14                       Pharmacology Teaching lab
                                Pharmacology Teaching lab
T.L. 4.17                       Prep Room
C39                             Inside CRL
C25                             Inside C25
C18                             In corridor outside C18
C26                             Wynick Lab
C32                             EM lab
D3                              In corridor outside D3
DW5                             ISL
D.24                            Medical School Porters Lodge
E.34                            First Aid room
E. Floor                        Corridor near E3
E. Floor                        Corridor near E21
E.30a Ordinary First Aid
Kit                             Post Room
E.30a Travel First Aid Kit      Post Room
E.30a Burns Kit                 Post Room
F floor                         ISL
F floor                         Corridor near F.37
F9                              Inside F9
F10                             Inside F10

By each box is a notice listing the names, laboratory/room numbers and internal telephone
numbers, for all the Medical School First Aiders. In the event of personal injury, an accident
report form MUST be filled in a.s.a.p. (available from the Safety Advisors)


Persons working with cyanide should do so during normal working hours and must inform
their PI / colleagues of their actions. A comprehensive risk assessments must be in place
detailing the staff training / strict procedural controls necessary to reduce the risk to
acceptable levels.
If cyanide poisoning is suspected, seek medical assistance immediately, the internal
telephone number for AMBULANCE SERVICE is external 999 and then ring 112233.
Further information can be obtained here-

The compounds Material Safety Data Sheet and procedure risk assessment should be taken
with the poisoned person, (where possible) together with any information on dose /
exposure route etc.


An accident report form must be completed and returned to the DSA‟s after all accidents.
The accident form can be found here
This form can also be used to report any hazard or incident which could potentially cause an
accident eg. loose floor covering, broken fire door etc, available from the Dept. secretary or
Safety Advisors.


Only competent trained staff are allowed to move / replace cylinders and their regulators in
the Department. All potential new users must be trained by a competent departmental person
in the necessary procedures and then read / sign the risk assessment in the appropriate gas
cylinder store. The new user must ensure they understand all the critical safety points
before they sign the departmental risk asessment and are allowed to change cylinder
regulators / move cylinders and attach them to gas supply systems. E.g. Use of cylinder
trolleys / manual handling risks / use of PPE / regulator use and their attachments etc..

Please contact your DSA‟s for details, the Gas cylinder risk assessment can be found in all
the departmental gas supply rooms.


Everyone working in the Department laboratories is exposed to chemicals / agents with
potenial COSHH risks, the department / UOB requires all groups to keep risk assessments
for chemicals with the followiing COSHH symbols-

Very toxic                                           Explosive

Mutagen                                              Carcinogen

Biohazard                                            Teratogen

These risk assessments should identify and control any potenial hazards / risks at the volume
/ concentrations used by the workers in the area specified by the risk assessment.

The use of radioactive compounds and GM / Biohazard work (cat 1 / 2) is covered by
the their specific local rules / risk assessments.

The use of the remaining compounds / agents used in the department is covered by the use
of good laboratory practice and the judgement of the areas person in charge (PI). No worker
should be exposed to harmful amounts of any chemical and the careful use of personal
protective equipment combined with good laboratory technique should ensure that all work
can be undertaken without significant risk. All new workers must be assessed for
competenace by the area PI and any necessary training given by competent workers before
they are allowed to work without supervision.
This section aims to provide guidance on the normal controls / work practices necessary to
handle and control exposure to COSHH risks. This section represents the minimum level
required for work in a general laboratory.

              (GLP) Storage / purchasing of Chemicals and their transport
      Purchase the smallest quantity / lowest concentration of any chemical / agent needed
       and in the safest form possible i.e. pellets rather than powder to minimise inhalation
       risks, solutions rather than solids to remove a handling step.

      Store all chemicals in their original container or a well-labelled container with the
       appropriate hazard warning clearly identified (either using one of the special yellow
       hazard code labels or a circled letter made with a permanent marker).

      Store all chemicals / agents following storage conditions specified by the supplier. If
       in doubt, store in a cool, dark place. Do not store chemicals in bright sunlight or
       above eye-level wherever possible.

      Winchesters should always be transported using secondary containment, containers
       should never be carried by the neck but should be supported with both hands, with
       one beneath the container

      No open containers should be carried in corridors and users should always have a
       ungloved hand available to open doors etc(a purple glove should be worn). If this is
       not possible the assistance of a second person should be sought before the procedure
       is implemented.

      All hazardous flammable chemicals must be stored in a fire retardant enclosure or
       suitable fume cupboard. The users must ensure that no possible dangerous mixtures
       of chemicals are stored together e.g. concentrated acid / alkalines, chloroform and
       methanol etc.

      All chemicals should be returned to their storage areas when finished with / at the
       end of the working day.

      A yearly stocktake should be undertaken by all laboratories and all unnecessary / old
       chemicals disposed of.
                              (GLP) Laboratory basic principles
      Dress properly and appropriately in the lab (see next section on personal protective
       equipment). Take all necessary precautions to reduce your exposure to the
       substances you use / come into contact with during your work.

      Plan your experiments so you use the minimum amount / concentration of all
       chemicals / substances used and reduce the exposure time.

      Do not embark on a new or unfamiliar procedure until you have been fully trained
       and your PI has deemed you competent. Ensure that you understand what all the
       potential hazards / risks and their safety controls are, before starting any procedure.
       Do not start the work if you are not satisfied with the provision of safety equipment
       or training. If in doubt at any stage, stop work and ask for advice.

      Always investigate any possible chemical interactions (e.g. strong acid / alkaline)
       and their effect on the potenial hazards / risks before starting any procedure.
      Good housekeeping in all work areas is essential for a safe working environment.

      Ensure benches and floors are tidy and free of unnecessary equipment

      Work in an orderly and organised manner.

      Avoid inhalation of hazardous dusts, aerosols, gases and vapours by working in a
       fume cupboard wherever necessary.

      Avoid ingestion of hazardous substances by mouth by ensuring that you

           o   Do not pipette by mouth

           o   Do not eat, drink or smoke

           o   Do not lick labels, chew pencils, chew your nails, etc

           o   Do not store food or drink in any laboratory.

      Remove your laboratory coat and any other protective equipment, and wash your
       hands before leaving the laboratory.

      Be conscious of the safety of cleaning and maintenance staff. Never leave chemicals
       or equipment in a dangerous condition.

      Before you start an experiment, think about the possible consequences of something
       going wrong.

      Make provision for spills etc before they occur

      If an accident occurs, keep calm and take any remedial action

      If necessary shout for assistance.
                       (GLP) Use of Personnel Protective Equipment

   Every individual must (Section 7 “Health and Safety at Work Act 1974) take
reasonable care for the health and safety of themselves and of other persons who may be
affected by their acts or omissions at work.
To co-operate with management to enable the employer to carry out his legal duties or any
requirements as may be imposed.

All area supervisors / PI‟s must ensure their staff are competent / trained to perform all the
tasks required of them, all personnel performing any procedure / work which might
constitue a hazard must wear the appropriate Personel protective equipment- the use of
lab coats is a minimum requirement when working in any Departmental laboratory.
All new / current staff memebers must consult their PI and the appropriate risk assessment /
local rules before undertaking any new procedures, to ensure all the necessary precautions /
control measures are implemented.

      Laboratory coats should be worn and fastened at all times when working in a
       laboratory and should be changed and laundered regularly.

       It is acceptable for people who are not directly involved in laboratory work activities
       to enter a laboratory without wearing a laboratory coat, unless the local rules require
       all persons to wear them. This may include persons who briefly go into the
       laboratory to speak to a colleague or individuals being shown around the laboratory

      Wear Safety Glasses when working with liquids or other material which could get
       into your eyes.

      Footwear that properly protects the foot from chemical splashes should be worn at
       all times in the laboratory.

      Special gloves should be worn when handling very hot, very cold, sharp or otherwise
       dangerous objects. For handling chemicals, the choice of glove material is important.

      Ear protection is available and should be worn when using noisy equipment
       (especially at 80db or above).

      If possible use plastic lab wear (beakers, flasks, pipettes, disposable pipettes,etc).
       You greatly reduce the risks of breakages and consequent injury.

      Dust masks are available from stores for use when dusts are being created. Ask
       advice from your PI / DSA‟s as to the most appropriate for your use.

Chemical spills

Alls groups undertaking procedures with the possibility / risk of significant chemical spills
must have spillage pillow / spill kits close at hand. This should be detailed in the procedure
risk assessment (including locations of spill kits) together with any special disposal

The department has spillage pillows available in DW3b and the Pharmacology teaching


In work outside of normal hours(before 8.00am and after 6.00pm), where there is an
obvious and significant possibility of the person concerned being incapacitated through the
work activity, special precautions should be taken,

1) The procedure / work must be discussed with your supervisor and Safety advisors
(G.Young 11442, D. Martin 12307/12308 before you start).

2) A second person should be within earshot, but not necessarily in the same room.

The Head of Department will make special arrangements as necessary if the person working
late has any physical disabilities.

An internal telephone must be readily available to anyone working late.


All equipment that is left on overnight must have a notice on it stating that it must remain
so, otherwise it may be switched off by night security patrol men. The notice must also
detail any hazards associated with the equipment, actions in emergency, and contact details
of the person responsible for the equipment.

Personnel heaters should not be left unattended.


BLUE round plastic bins are for waste paper/office refuse ONLY. These bins and small
empty flat-packed carboard boxes will be emptied and collected correspondingly by the
cleaner from inside offices but from outside labs Large boxes, after flattening, will be
collected by the porters, ring ext.87462.

BLACK PLASTIC BAGS can be obtained from the Departmental Administrator / stores,
to line the larger RED square plastic bins for general laboratory waste inc. gloves , paper
towels , plastics etc.

DO NOT dispose of general laboratory waste in the blue bins. Full black bags must be
taken and disposed of in the large green bins at the back of the Medical School by lab
personnel themselves.

RECYCLABLE materials: A box for empty metal drinks cans is situated in the
departmental coffee room. A box for spent copier paper is placed beside the photocoping
machine and in the mail room. Each lab/office is provided with a blue recycle bin which is
also collected by the cleaner in the same manner as waste paper collection. The
departmental representative for recyclable materials is A.Harris (4.14, Teaching Laboratory,

Ethidium Bromide / Acrylamide Gels –

If you use ethidium bromide or acrylamide gels - the waste must be put into proper thick
incinerator bags (ordered from Path and Micro). These bags can be fitted into pedal bins for
easy use.
When the bag is full it must be placed inside a second incinerator bag, sealed, labelled and
taken down to B floor and placed in the holding box in the outside liquid nitrogen pen.
Labels can be obtained from path and micro(on holding box)and must be filled out with
group name, department, date, and contents of bag.

Room Cleaning

There are set rules for cleaners working in the departmental offices,laboratories, etc.

Cleaning staff will clean offices/communal areas (kitchen/corridors etc) without prior

Cleaners / staff must follow the access restrictions below for the 4 types of laboratory within
the department,

1)        Laboratories with no sign on door - can be cleaned without prior arrangement.
2)        Laboratories with yellow coloured 'Category 1 Laboratory' sign on door - must
only be cleaned with prior arrangement with the laboratory supervisor / laboratory staff.

3)        Laboratories with yellow coloured 'Category 2 Laboratory' sign on door - must
only be cleaned with prior arrangement with the laboratory supervisor AND the
Departmental Deputy Biological Safety Officer /Deputy(G.Young, D.Martin), who will
ensure the laboratory is safe to be cleaned.

4)         Laboratories with the yellow and white coloured 'Supervised Area' radiation
trefoil sign on door - should be cleaned ONLY with prior arrangement with the laboratory
supervisor AND the Departmental Radiation Protection Supervisor / Deputy (G.Young, D.
Martin), who will ensure the laboratory is safe to be cleaned.

In addition to this information, a mop and bucket will be assigned to each Cat 2 room
specifically and should not be used anywhere else. The mop head must be sent to CMM for
disposal after use(like normal Cat 2 waste)and the waste water treated over night with
Verkon and then disposed of down the drain. The cleaner must wear one of the blue
laboratory coat provided in each cat 2 room and leave it in the room when finished.

If there are any special considerations relating to general laboratory safety, they should be
discussed between the departmental administrator / departmental DSA‟s , and the cleaning
                                                                              HOW TO DISPOSE OF WASTE IN THE MEDICAL SCHOOL

All Offices, including offices within laboratories                                             Staff emptying bin   Treatment before disposal              Waste Disposal Route
Paper: includes staples, paper clips, sellotape                                                Cleaning             N/A                                    Placed in external recycling bin

Confidential waste paper: as defined by resolution of Senate                                   Departmental         N/A                                    Collected by/taken to porters

Aluminium and steel drink cans                                                                 Cleaning/Lab.        Must be empty                          Placed in external recycling bin

Cardboard boxes                                                                                Portering/Lab.       Flattened by Laboratory staff          Placed in external recycling bin

Office rubbish bin: newspapers, plastic wrapping etc.                                          Cleaning             N/A                                    Placed in external rubbish bins
Standard lab, different types of waste produced                                                Staff emptying bin   Treatment before disposal              Waste Disposal Route
Metal waste: old equipment, fridges etc.                                                       Laboratory           N/A                                    Placed in external metal skip

Non-metal large piece of waste: furniture etc.                                                 Laboratory           N/A                                    Contact Dept. Superintendent

Hazardous liquid or solid waste:                                                               Laboratory           Taken to Health + Safety Office        Collected by Contractor
hazardous chemicals, solvent waste, paints, pharmaceuticals, stock solutions, pesticides &
labware involved with very hazardous chemicals (inc. gloves, syringe barrels and pipette

Laboratory bin for general laboratory waste:                                                   Laboratory           N/A                                    Placed in external rubbish bins
paper towels, gloves, empty plastic containers (must be rinsed out), other plastics, syringe
barrels and tips NOT used for hazardous, chemical, clinical or biological material

Glass bin for non-hazardous glass: broken glassware & glass bottles                            Laboratory           Washed out                             Placed in external rubbish bins

Empty Merck & Fisher containers or packaging                                                   Laboratory           Washed out                             Given to Stores for recycling

Cin bin for sharps: needles, scalpels, blades, (& glass in biological labs)                    Laboratory           Taken to Path + Micro                  Put in Clinical external waste bin
Must be labelled with source and marked “glass” or “no glass”

Electrophoretic gels                                                                           Laboratory           Taken to Cellur and Molecular Biolgy   To V S/Langford for incineration

Animal waste: animal tissue & gloves, tissues, swabs used during dissection                    Laboratory           To H floor & put in freezers           To V S/Langford for incineration

Human waste: human tissue & gloves, tissues, swaps used during dissection                      Laboratory           By specific protocol                   Contact Dept. Superintendent
Biological lab, different types of waste produced                                                Staff emptying bin   Treatment before disposal                    Waste Disposal Route

Lab bin for general waste: paper towels, gloves, empty plastic containers(must be rinsed         Laboratory           Autoclaved (wet) by P & M                    Placed in external rubbish bins
out), used petri-dishes, tissue culture plates and all plastics including biologically
contaminated ones, syringe barrels, tips etc.

Aqueous waste: includes media containing microbiological material                                Laboratory           Autoclaved (w) by Media Dept                 Poured down sluice into drains

Reusable labware: includes measuring cylinders & glass pipettes                                  Laboratory           Autoclaved (d) by P & M                      Taken back to laboratories

Different types of lab. equipment: which might have become contaminated                          Laboratory           Seek advice from Health + Safety Office      Taken back to laboratories
Radioactive lab, different types of waste produced                                               Staff emptying bin   Treatment before disposal                    Waste Disposal Route
Solid radioactive waste: includes glass vials, syringe barrels and tips see Work with Ionising   Radiation workers    See Code of Practice                         Placed in external rubbish bins
Radiation code of practice

                                                                                                                      Taken to Health + Safety Office              To Langford for incineration

Cin bin for sharps: needles, scalpels, blades                                                    Radiation workers    Decontaminate material                       Placed in ext. clinical waste bin
Must be labelled with source and marked “glass” or “no glass”

Liquid/organic radioactive waste: see Radiation code of practice                                 Radiation workers    Taken to Health + Safety Office              To Langford for incineration

Aqueous radioactive waste: see Work with Radiation code of practice                              Radiation workers    See Code of Practice                         Poured down designated sink

Animal waste: see Work with Ionising Radiation code of practice                                  Radiation workers    Macerated in B6                              Poured down designated sink

                                                                                                                      To H floor, then to Health + Safety Office   To Langford for incineration

Electrophoretic gels: containing radioactive material                                            Radiation workers    Macerated in B6                              Poured down designated sink

                                                                                                                      Taken to Health + Safety Office              To Langford for incineration

Animal House, different types of waste produced                                                  Staff emptying bin   Treatment before disposal                    Waste Disposal Route
Animal food and bedding: animal wastes and residues                                              Animal house         Placed in external blue skip                 Collected by BFI waste

Category 2 animal food and bedding: animal wastes and residues                                   Animal house         Autoclaved (w) in Animal House               Placed in external blue skip

Animal remains (including both Category 1 & 2 material): all carcasses and gloves, tissues       Animal house         Placed in dedicated freezers                 To V S/Langford for incineration
& swabs used during dissection

Category 3 animal remains, food & bedding: all carcasses etc. and animal wastes and              Animal house         By specific protocol                         By specific protocol

                                                                                                                                                             Issued By Med. School Administrator November 1998

SHARPS BINS - available from Biochemistery stores, are used for disposal of used
razor blades, scalpel blades, needles and syringes. DO NOT dispose of "sharps" in
the blue or red bins. Full Bins should be taken to CMM for disposal.

GLASS - broken glass/empty bottles/glass pipettes - MUST be disposed of in
dedicated glass bin or directly into the green bins in B back.

Non-hazardous empty chemical containers (glass/plastic) can be disposed of AFTER
 thorough rinsing out. Empty hazardous chemical containers/gels please refer to the
safety advisors.


1. In the case of all electrical appliances, all wires should be visible for inspection and
if they show signs of wear or damage, should be repaired immediately.

2. Wiring MUST NOT BE OVERLOADED (max 13 amp limit), otherwise it will
overheat and the insulation will be damaged.

3. Plugs must only be replaced by a competent / trained member of staff and a pat test
performed afterwards.

4. Use of distribution boards should be minimal.

Equipment with heat elements or generate high loads( 6 Amps or above, such as water
baths), MUST be connected to a wall socket, NOT a distribution board.
Distribution boards MUST NOT be "daisy chained" together. Distribution boards
must always be bought for the purpose, staff must never attempt to make their own
distribution boards from a kit of parts. If a specially made electrical distribution
system is needed for a rig, the electronics technicians must oversee its manufacture
and instalation.

All portable appliance equipment will be PAT-tested according to the Departmental
Pat test code of practice– DO NOT USE any equipment which does not have a
sticker, or test is out of date, if in any doubt, please contact the Departmental Safety
Advisors / electronics technicians.

Only oil filled Personnel heaters (with up to date pat test sticker) are allowed in
the department.


The following Codes of Practice are available from the safety advisors.

4.     ELECTRICAL SAFETY- October 2001
8.     MANUAL HANDLING-July 1998
10.    MECHANICAL SAFETY- February 1999
11.    OFFICE SAFETY- October 2002
12.    RISK ASSESSMENT – November 2001
14.    SAFETY AUDITS – November 2001

The following guidance notes are also available -

1. Loan of personal tools - 1996
2. Allergy to animals - 1996
2a. Students and allergy to animals - 1997
3. Personal safety at work - 1997
4. Home working - 1997
5. Lap top computers - 1998
6. Use of electricity and electrical equipment - 1998
7. Skin care at work - 1999
8. Handling of discarded needles and syringes etc – 1999
9. Statutory testing/examination – Departmental Duties – 2000
10. Handling liquid nitrogen – 2002
11. Guidance for producing a COSHH assessment for fumigation of biological safety
    cabinets and rooms - 2002


The COSHH Regulations, 2002, state that employers shall not carry out work which is
likely to expose employees to hazardous substances unless they make "a suitable and
sufficient assessment of risks created by that work to the health of those employees".
When ordering any chemical, its COSHH assessment must be indicated on the order
form, and if it requires a risk assessment of use, one needs to be completed and sent
to the safety advisors, who will then aprove the order

Chemical listings detailing all the chemicals present and special COSHH assessment
forms giving more information on those chemicals which are assessed as being either
Very Toxic, Carcinogenic, Mutagenic, Teratogenic or Biohazard are displayed in
each departmental laboratory.
Standard chemicals are assessed by adhering to „Good Laboratory Practice‟, while
special assessments list the name of the chemical, quantity and form, its COSHH
assessment and potential exposure hazard, along with its toxicity data eg. LD50 value
and/or exposure levels ( short term / 8 hour)
Each chemical on the special assessment form, must have a corresponding risk
assessment of use form completed , detailing how it is to be used and precautions to
be taken when handling, containment measures, emergency procedures in case of
accident, etc.
In the event of a large spill, Powersorb absorbent pillows should be used. For further
safety information, chemical data sheets, and hazardous chemical disposal, please
contact the Departmental Safety Advisors.

It is Departmental policy that if it is required to wear gloves to protect samples while
transporting between labs, ie using communal corridors, then a non-latex, PURPLE


All workers must read and sign the departmental risk assessment (Departmental risk
assessment folder can be obtained from the safety advisors) for the use of liquid
nitrogen before commencing work. Additional information can be found here-


Two 1992 European Community Directives require general precautionary measures to
be taken within all workplace environments which includes offices and specific
precautions to be taken with respect to the use of display screen equipment, the main
hazards of which are musculo-skeletal disorders, visual fatigue and stress. Therefore,
employers are required to carry assessments of workstations and then remedy any
shortcomings thereby identified DSE workstation assessments are monitored annually
by the safety advisors. Users are eligible for an eye-test every 2 years and VDU
spectacles if required, or cost towards prescription glasses. The Department considers
all academic, secretarial, computer, and senior technical staff to be users.


The code of practice concerning manual handling, describes guidelines for the lifting
and lowering of objects. In the case of heavy objects, there is an assessment checklist
which assesses risk of personal injury and requires a remedial action report if a risk is
Further information can be found here-


It is in the best interests of pregnant women to inform the Head of Department/Dept
Administrator/ safety advisors in confidence and as soon as possible.
New risk assessments/systems of work and /or existing assessments may need to be
completed/ammended for use of chemicals, manual handling activities, use of specific
equipment, etc to reflect pregnancy and ensure that work undertaken cannot harm the
mother or the unborn child.
Additional information can be found here


It is now ilegal to smoke in the Medical School and Teaching Laboratories Building.
See below link


Departmental risk assessment forms are held in a folder by the safety advisors, if you
are going to undertake a new activity which requires a risk assessment please contact
the safety advisors for advice.

Currrent departmental risk assessments cover activities such as use of the autoclave in
DW3b, movement of gas cylinders , use of –80oC freezer etc.
If you are involved in any activity where a risk assessment exists, you must first read
that assessment and sign to indicate you have done so.

A room/lab risk assessment summary information sheet is posted on the Dept. Safety
notice board, and is updated annually. This details when and by whom certain
tests/assessments common to all or most departmental working areas are carried out.

Before any outside contractors (e.g. builders, window cleaners, service contract staff)
or University Building Services Dept (e.g. plumbers, electricians) employees begin
work in any departmental laboratory, the room must be risk assessed and an clearnace
certificate/assessment form must be placed in a visible position on the door of the
inspected laboratory. This certificate details room number, contractor, dates work will
occur and duties for which the certificate has been issued, and any major hazards
(radiation/chemical/biological/slips,trips and falls), and the precautions taken to
minimise any risk before contractor is allowed access. The form is signed off by the
safety advisors before work commences.


PRODUCTS OR HUMAN TISSUE. A risk assessment must be made for all work
involving handling of blood , blood products and other human tissues, specifically for
the procedures involved and the nature and source of the samples to be handled.
Where it is known or strongly suspected that specific hazard group 3 pathogens (HBV,
HIV) are present then the samples must be handled at the corresponding containment
level (see Flow Diagram and Codes of Practice), and the Biological Safety Officer
(BSO) informed before work starts.
In many cases however, it is not known which pathogens (if any) the samples may
contain and therefore universal handling precautions should be adopted in the
laboratory not to the extent of specifying Containment Level 3. All work on
unscreened samples must be undertaken at a minimum of Containment Level 2,
which in general does not need to be confined to a safety cabinet unless there is reason
to believe the specimen contains other pathogens that do require such containment.

University Biological Safety Officer ext. 88783) AND TRAINING FOR

The following precautions must be taken when samples requiring Containment Level
1 and 2 are handled.

For all samples:

1. Eating, chewing, drinking, smoking, applying cosmetics, storing of food and
   outdoor clothing in the laboratory is banned.

2. Mouth pipetting must not be used under any circumstances for any reason.

3. All workers in the laboratory must cover cuts and abrasions with a waterproof

4. Wash hands regularly and always before leaving the laboratory.

5. Neck fastening laboratory coats must be worn at all times whilst in the laboratory
   and removed before leaving.

6. All specimen containers, glassware and used equipment must be immersed in 10%
   bleach before cleaning or disposal.

7. Surfaces must be disinfected with 1% Virkon following spillages, dry virkon
should be shaken over large spills before being cleaned up. Bench tops must be
disinfected after use.

8. Accidents
               i) In the event of an accident resulting in a wound
                  immediately encourage it to bleed, wash thoroughly
                  with soap and water but DO NOT SCRUB, cover with a
                  waterproof dressing.

               ii) In the event of contamination of skin, conjunctivae or mucous
                   membranes immediately wash thoroughly.

               iii) Accidents must be reported to Gareth Young or Debbie Martin
               (DSA)- 11442 or 12307 OR Angela Wells (Path & Micro)- 12207
                The accident form can be found here


Additional precautions:

1. Use sharps when there are no alternatives. Used sharps must be placed directly
   into cin-bins for autoclaving.

2. Disposable gloves must be worn at all times (and not re-used) when handling
   samples and be removed before leaving the laboratory. In the event of gloves
   becoming damaged or grossly contaminated the gloves must be discarded, hands
   washed and fresh gloves put on.

3. Eye protection (goggles or safety glasses) and a plastic apron should be worn if the
   work activity is likely to cause splashing.

4. Materials must only be handled at clearly identified, designated work stations. On
   completion of work, the work station must be disinfected.

5. Samples must be centrifuged in sealed safety buckets.

6. All waste materials must be made safe before disposal.

BLOOD COLLECTION - There is a designated room for the collection of blood
E40, the booking of which can be arranged through Angela Wells (Path&Micro) on
ext.12207 – Room G53


Your Local Departmental Biological Safety Officers (DBSO) are Gareth Young &
Debbie Martin, and can be contacted in Room 4.14 & 2.2 / 3.3 or telephone
ext.11442 & 12307

Experiments involving genetic modification must be approved by the University
Biological Safety Committee and/or HSE under a project application and may only be
carried out in authorised laboratories - Before work begins, users must have read and
be familiar with the Departments own local rules for use of genetically modified
organisms, and be registered – forms available from the DBSO

The following procedures are the minimum requirements in a laboroatory authorised
for genetic modification experiments, and MUST apply at all times.

1. Laboratory coats, high neck, and fully fastened must be worn in the laboratory.
When working in an exhaust protective cabinet, gloves should always be worn.
Protective clothing (including gloves) designated for use in a containment laboratory
must not be worn outside the facility.

2. Eating, chewing, drinking, smoking, storing of food and applying cosmetics must
not take place in the laboratory.

3. Mouth pipetting must not take place.

4. Hands must disinfected or washed immediately when contamination is suspected,
after handling viable materials, and also before leaving the laboratory.

5. All procedures must be performed so as to minimise the production of aerosols.
Special care must be taken when using centrifuges.Laminar flow cabinets must not be

6. Effective disinfectants (1% virkon) must be available for immediate use in the
event of spillage. Use dry Virkon on large spills.

7. Bench tops should be cleaned after use.

8. Used laboratory glassware and other materials awaiting disinfection must be stored
in a safe manner.Pipettes, if placed in disinfectant, must be totally imersed.

9. All waste material must be rendered non-viable before disposal.

10. Materials for autoclaving must be transported without spillage in robust leakproof

11. All accidents must be recorded and the DBSO (DepartmentaL Biological Safety
Officers informed. Ext 11442 & 12307/8)

Children on Departmental Premises


As required by Council, the Department of Pharmacology has formulated the
following policy for the protection of children on its premises. This policy is to be
adhered to by all students, members of staff, and visitors to the Department.


1    Children are not permitted on Departmental premises outside normal working
     hours ( Portering staff on duty ).

2     Children are not allowed at any time in the following areas, which
      are considered to be of high risk:

      (i)    All research laboratories (including the scintillation counting room and
             tissue culture facilities).

      (ii)   All teaching laboratories.

3     Any student or member of staff bringing children into these areas will be
      committing a disciplinary offence.

4     Children are allowed into offices and the communal coffee area if supervised by
      an adult.

5     Where possible the Head of Department should be notified in advance.

6     Students, members of staff, and visitors, must exercise close supervision of
      children at all times when they are on Department premises.

7     Special arrangements will be made for supervision of school parties and other
      organised groups.The Head of Department must be notified well in advance of
      any such proposed visit in order that those arrangements can be put in hand.


New members of staff who are going to work with animals, must contact the
Occupational Health department and undertake a baseline lung function test before
they start animal work.

Occupational Health
Hampton House Health Centre,
St Michael's Hill,
Bristol BS6 6AU
Tel: 0117 330 2572, F: 0117 330 2699

links to the forms are below-

Baseline test-

6/12 week test

Annual questionarire-

All animal use within the department must be undertaken following the University
guidelines. Some of the basic points are as follows-

1.      Animals can only be used in registered laboratories and cannot be kept in the
        laboratories overnight

2.      All animals users must be competant in the procedures used (schedule 1 killing
        etc.)and be registered with Occupational health for annual lung function

3.      H floor must be informed of all animal procedures to ensure compliance with
        home office legislation (i.e. personel Licences / schedule 1 killing).

4.      All workers using animals must wear the appropriate personel protective
        equiment when handling animals and working on H floor. The wearing of a P2
        face mask, gloves and laboratory coat is the minimum requirement and

     additional protection may be needed for some procedures / curcumstances
     (contact DSA / H floor for information ).

5.   Animal users must ensure the safety of other workers in the vicinity(control of
     animal allergens) by the use of mechanical control measures and barriers e.g.
     fume cupboards, protective covers for animal cages.

6.   Room ventilation must be considered to prevent animal allergens being vented
     out of the controlled area (into corridors/ adjoining rooms).

7.   Animal carcases must be taken to H floor for disposal in an airtight container.

8.   Use of GM animals must be covered by a risk assessment or written GM
     project registered with the University safety office / H floor.

9.   All animal workers must be constanly aware of animal allergen
     sensitisation and any reaction to animal allergens must be brought to the
     attention of the DSA and occupational health immediately.



All new members of staff must go through the preliminary Departmental induction
process organised by the Departmental secretaries and Have a detailed discussion
with your supervisor covering all aspects of the work, including careful
consideration of safety issues. This must also take place on each occasion when
you propose using a new technique.

1 General Safety

Read the General Departmental Safety rules, sign and return the declaration at the end
of the document(return to the Departmental Office).

2 GM / Biological

All new members of staff who are going to work with GM material must contact
the Departmental Safety advisors before they start work.

Before work begins, users must have read and be familiar with the Departments own
local Safety Rules for use of genetically modified organisms and be registered with
the UOB– forms available from the UOB

3 Radiation

All new members of staff who are going to work with radioactive material must
contact the Departmental Safety advisors before they start work.

Before work begins, users must have read and be familiar with the Departments own
local Safety Rules for use of radiation and be registered with the UOB– forms
available from the UOB Safety web site.

4 Animal

All new members of staff who are going to work with animals / animal tissue
must contact the Departmental Safety advisors before they start work.
You also must contact Occupational health to organise a lung function test.

Your Local Departmental Safety Officers are Gareth Young & Debbie Martin, and can
be contacted in Room 4.14 & 2.2 / 3.3 or telephone ext.11442 & 12307


I have received, read and understood the General Safety Rules for the Department of
Physiology & Pharmacology, Medical School, Bristol. I will contact the Departments
Safety Advisors before commencing work if any of the points under the safety
induction procedure above apply.

Signed        ………………………………………….

Print Name    …….........................................................

E.mail        ………………………………………….

Date          ………………………………………….

G.Young 03/06/08

To top