Joint Transplantation Program Your Gift and the Joint Transplantation Program Thank you! Through your generous support, the Joint Transplantation Program is moving towards a promising future. The focus continues to be on improving bone and joint health care through innovative research projects, and translating the resulting knowledge to clinical applications that will benefit all Albertans. In appreciation, we are pleased to provide you with an update on the program’s progress. McCaig Institute for Bone and Joint Health Joint Transplantation Program Last year we reported on the first fresh Photo (Left to Right): bulk osteochondral allograft procedure Carol Hutchison, MD, MEd, FRCSC, performed in November 2006 by Associate Professor, Division of Orthopaedic Surgery, Dr. Carol Hutchison. The surgery was University of Calgary extremely successful. The patient, Eltoff Abdalla, continues to enjoy Dr. Norman S. Schachar, MD, FRCSC significant improvements in her quality Professor, Division of Orthopaedic Surgery, of life. This was happily evident when, University of Calgary in April 2008 she comfortably walked down the aisle at her wedding. The McCaig Institute for Bone and Joint Health / Joint Transplantation Program continues to spearhead and implement advancements in musculoskeletal health, including the “ Our program has the potential to change the course of aforementioned knee transplant surgery. treatment for many patients with joint injury, to prevent or at least delay the need for a total joint replacement – The success of the program is due largely to the unique cooperative setting a new standard of treatment in Orthopaedics partnerships between scientists, for years to come.” clinicians, the Calgary Heath Region C aro l H uTCH I so n , M D, M E d, FrCsC and the Southern Alberta Associate Professor Tissue Program. Division of Orthopaedic Surgery University of Calgary Treatment options Currently, the Joint Transplantation Program offers treatment options for young patients with two types of knee injuries: traumatic bone and cartilage joint defects and isolated “ Biological treatment damage to the articular cartilage. options are the future of Orthopaedics.” Two types of procedures are available to treat these injuries: fresh bulk sCoT T TI M M E r M an , M D, FrCsC osteochondral allografts Division of Orthopaedic Surgery University of Calgary and stored osteochondral dowel allografts. By utilizing a biological intervention for joint transplantation, these new procedures set a new standard in health care. Education and Scott Timmerman, MD, FRCSC Division of Orthopaedic Surgery outreach University of Calgary Several initiatives have been taken to inform the medical In collaboration with the Office of community that there are now Continuing Medical Education at the two new joint injury treatment University of Calgary, the Joint Demand options available in Calgary. Transplantation Program is looking to As evidenced by the number of current recruit such experts as Dr. Ross Wilkins, patients on the waiting list (three  for In March 2007, Drs. Schachar, a fresh bulk osteochondral allograft Co-Medical Director of the Denver Timmermann, Hutchison and Muldrew and three  for an osteochondral dowel Institute for Extremities at Risk, to initiate delivered a presentation at city-wide allograft), these surgical procedures a guest lecture series. Dr. Wilkins is an surgical rounds entitled “Biological are in demand. internationally recognized expert on Solutions in Joint Re-construction: Limb Preservation, Bone and Soft Tissue Bone and Cartilage Transplantation”. It is anticipated that the need for these Tumors, and Bone Transplantation. A letter was also mailed out to all types of surgeries will increase as Feedback on the education and outreach Orthopaedic Surgeons in southern orthopaedic surgeons and sports programs has been very positive. The Alberta to notify them of the availability medicine physicians throughout southern medical community has embraced the of these procedures. Formal, interactive Alberta become more aware that these goals of the Joint Transplantation presentations have been developed biological treatments are now an Program and thus it will continue to and will be delivered by members of option for appropriate patients. expand in the future. the Joint Transplantation Program Working Group to Orthopaedic In addition, articles related to the Surgeons in Red Deer, Medicine Hat, Joint Transplantation Program, written Lethbridge and Banff in the coming year. by working group members, have recently been published in IMPACT Magazine and the Journal of Cell Preservation Technology. Progress All the short-term goals from research Basic research projects will For more information on the the last update have been Joint Transplantation Program, achieved. continue to focus on developing please contact: The restructuring of the Southern Alberta effective ways to extend the Sue Hunter, MSc Coordinator, Tissue Program in the Calgary Health storage times for banking Joint Transplantation Program Region has directly impacted the ability osteochondral tissues. 403. 220. 3119 to acquire the donor tissues needed to email@example.com perform more transplants. As a result, Researcher Ken Muldrew, along with his the time line for achieving the mid-range colleagues in Edmonton, is close to identifying techniques to freeze cartilage For more information on reach!, goals has been re-evaluated and the please contact: system is now fully operative. Once for transplantation. This would be revolutionary because it will eliminate Val Duggan suitable donor tissue becomes available, Director, Donor Stewardship, Reach! the Joint Transplantation Program looks the risk of disease transmission (currently 403.943.0622 forward to the next fresh bulk 1 in 119,000) and allow more time for firstname.lastname@example.org osteochondral allograft, as well as the scheduling surgeries, particularly for www.reachforhealth.ca first hypothermically stored osteochondral patients from rural areas. dowel transplant that will be performed For more information on the by Dr. Scott Timmermann. In the next few months collaborations alberta Bone & Joint Health Institute, will be initiated with colleagues in please contact: The long-term goals remain unchanged Radiology to investigate the use of T2 Judy Crawford from the last report and the program is mapping and 3D GRE techniques with 403. 220.4554 moving forward with enthusiasm. magnetic resonance imaging to develop email@example.com improved objective outcome measures www.albertaboneandjoint.com Increased communication and education for monitoring the success of grafts, are top priorities, and plans are well under post-operatively. way. These efforts should lead to the identification of additional appropriate To fund the purchase of these patients and awareness of the need for diagnostic tools, applications will be suitable donor tissue procurement. submitted for both an equipment grant from Alberta Health and We have purchased a new refrigerator Wellness and a research infrastructure for hypothermically storing media and grant from the Alberta Science and osteochondral tissues for up to a month Research Investment Program (ASRIP). prior to transplantation. The Program has also been working closely with the Southern Alberta Tissue Program (SATP) to coordinate data loggers and software for monitoring temperatures of all fridges and freezers in which donor tissues are stored throughout the Calgary Health Region.