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152 THE KLEIHAUER TEST

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152 THE KLEIHAUER TEST Powered By Docstoc
					                                                15 ANTI D IMMUNOGLOBULIN




       Date Issued: January 2005                                                                     15.2 The Kleihauer Test
       Date Revised: July 2009                                                                                    Section 15
       Review Date: July 2011                                                                 Transfusion Medicine Protocols
       Authorised by: KEMH & PMH Transfusion Committees              Child & Adolescent & Women’s & Newborn Health Services
       Review Team: KEMH & PMH Transfusion Committees                                                Perth Western Australia


   ALSO see WNHS Intranet Clinical Guidelines

   Section A Medications 3.13 Rh D Immunoglobulin

   Section B: Obstetric and Midwifery Guidelines, 2.4 Blood Grouping, Antibody Screening
   and Rh D Immunoglobulin.




   15.2 THE KLEIHAUER TEST

         Kleihauer tests are not required in the first trimester as one minidose of Rh D Immunoglobulin will be
          sufficient to cover all events.

         Following FMH or delivery, a Kleihauer Test performed on a maternal sample is used to determine if
          additional doses of prophylactic Rh D Immunoglobulin are required.

         A Negative Kleihauer Test indicates that one dose of Rh D Immunoglobulin is sufficient. It is not
          necessary to wait for the result before administering Rh D Immunoglobulin.

         A standard full dose of Rh D Immunoglobulin (625 IU) is sufficient to destroy up to 6mL of packed fetal
          red cells.

         For FMH in excess of 6mL a repeat Kleihauer Test is required 48 hours after administration of Rh D
          Immunoglobulin to ensure effective prophylaxis.




HTMP 15.2                                                                                                        Page 1 of 1
             All guidelines should be read in conjunction with the Disclaimer at the beginning of this manual.

				
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