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A Systematic Approach To Disease Remediation

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					   A Systematic Approach to
Nutritional Disease Management


      Dr Melvyn A Sydney-Smith. KGSJ.
     Australian College of Holistic Medicine
             Doolandella. Qld. 4077
      Coordinator. Master of Nutrition Medicine Program
                   School of Health Sciences
                RMIT University. Melbourne.


     www.nutritionmedicine.com
Contributory Factors in Disease
Almost all illness is characterised by a limited number
   of physiological pathways arising out of cellular
   metabolism:
             1. Inflammation
             2. Infection
             3. Ischaemia
             4. Toxicity
             5. Senescence/Degeneration
             6. Neoplasia
Contributory Factors in Disease


Unchecked or uncontrolled, these “illness”
 processes result in structural damage and
 pathological change.


If the body has resources to maintain control of
   these processes then a health challenge can be
   successfully met and normal function and
   structure restored in the healing phase.
Contributory Factors in Disease

 The natural health practitioner has a wide
  range of therapeutic options to enhance the
  body’s resources and improve regenerative
  processes.

 When “illness” processes are corrected in a
  systematic, comprehensive manner, chronic
  degenerative diseases, so common in modern
  society, can be ameliorated and, in many
  cases, normal function and health restored.
Contributory Factors in Disease

Environmental Load
    Dietary nutrient composition
    Dietary chemicals
    Xenobiotic chemicals
    Heavy metals (mercury, lead etc.)
    Pathogenic organisms
       viruses, bacteria, parasites

    Social/Psychological   Stress
Contributory Factors in Disease

Interface Factors
      Biofilm integrity

      Digestive capacity/adequacy

      Mucosal permeability

      Protective secretory factors
Contributory Factors in Disease

Internal Factors
       Cell membrane permeability
       Phagocytic activity
       Inflammation mechanism activity
       Vascular integrity
       Immune system activation
       Hepatic detoxification
       Neurological function
       Hormonal function
       Tissue regeneration mechanism
A Systematic Nutritional Approach
To Clinical Disease Management

Integrated treatment requires
 attention to:
    DIGESTION
     DIET
     EFA BALANCE
     ANTIOXIDANT ADEQUACY
     BOWEL DYSBIOSIS
     SPECIFIC NUTRIENTS
            Inflammation mechanism
            Immune regulation
            Neurotransmitter balance
            Hormonal balance
     HEPATIC DETOXIFICATION
  A Systematic Nutritional Approach
  To Clinical Disease Management


DIGESTION : impaired digestion leads to :
   protein & nutrient deprivation
   excess bio-reactive peptides & nucleotides in the
   intestine
   increased mucosal permeability
   development of Bowel Dysbiosis
   results in inappropriate Immune Activation
   undue dependence on carbohydrate
   absorption and metabolism
A Systematic Nutritional Approach
To Clinical Disease Management


DIET : proper diet needs to be individualised to each
  person’s genetic requirements - general guidelines are:
   • low-chemical : xenobiotic contaminants & natural
   •   low allergy : grains, dairy, yeast, soy, eggs, nuts etc.
   •   high fibre : vegetable/fruit soluble fibre
   •   adequate protein : animal/vegetable mix
   •   nutrient dense : unprocessed, good quality foods
   •   beneficial fatty acid balance : n-3-FAs & n-9-FAs
   •   complex carbohydrate : vegetables, legumes, grains
   •   balanced meals : protein, fibre, starch and fruit
  A Systematic Nutritional Approach
  To Clinical Disease Management


Essential Fatty Acid balance : the ratio of
  -6-FAs / -3-FAs needs to be balanced -
  this is achieved by :
      •   reduction of saturated animal fats
      •   reduction of polyunsaturated vegetable oils
      •   increased use of monounsaturated oils
      •   increased use of linseed/flaxseed oil
      •   increased use of seafood & seafood oil
      •   adequate Vit B6, zinc, Vit C & Vit E
      •   judicious use of Evening Primrose oil
A Systematic Nutritional Approach
To Clinical Disease Management

Antioxidant adequacy :
 unchecked free radical pathology leads to disturbance of cell
 membrane permeability, disordered cell metabolism & tissue
 degeneration/disease : the antioxidant complex can be
 optimised by :
      Fresh fruit & vegetables
      Bioflavonoids, Green Tea, Grapeseed extract,
       Gingko etc -
      Vit C (2-8gm/d) -
      Vit E (500-1500U/d) –
      Zinc, manganese, copper –
      Selenium, - selenium
      cysteine, methionine, CoQ10, NAC, GTH
A Systematic Nutritional Approach
To Clinical Disease Management

Bowel dysbiosis : toxigenic bowel flora increases
  antigen load on the immune system -<AND>- the toxic
  chemical load on the liver –
  Restoration of normal flora is achieved by :
       optimisation of digestive efficiency

       increased dietary vegetable fibre

       supplements of lactobacillus & bifidobacteria

       increased fructo-oligosaccharides -

       control of intestinal thrush growth
        nystatin, caprylic acid, grapefruit extract,
        colloidal silver, biotin, garlic, berberine
  A Systematic Nutritional Approach
  To Clinical Disease Management


Hepatic detoxification : impaired deactivation of
  endogenous and exogenous chemicals leads to progressive
  tissue toxicity & poor cellular metabolism :

Detoxification mechanisms can be upregulated by :
   Removal of hepatotoxic drugs & chemicals
   Vitamin B-Co supplements
   optimising antioxidant intake & synthesis -
      Vitamins C & E, Lipoic acid, N-acetylcysteine
      liver protective herbs –
      liver detoxification protein powders
  A Systematic Nutritional Approach
  To Clinical Disease Management

Specific Nutrients :
Inflammation mechanism: in certain cases intensive
  control of inflammation is required & can be
  achieved by supplemental:
       -3-FAs and ?? Evening Primrose oil
       high-dose quercetin & bromelain
       herbal anti-inflammatory agents :
            Curcuma, Boswellia, willowbark, feverfew-
       increase adrenal corticosteroid activity:
         Licorice, Korean Ginseng, Bupleurum,
         Scutellaria
A Systematic Nutritional Approach
To Clinical Disease Management

Specific Nutrients :
Immune regulation: Specific measures to regulate immune
  function is often required & include :
 Nutrients - Vit A, C, E, B6, folate, B-co, Zinc,
  Selenium, germanium, iron etc..
 Herbal immune stimulants - Ginseng, Echinacea,
  Hydrastis, Astragalus, Rei-Shitake, Phytolacca etc..
 Hormonal stimulants - thymus, thyroid & adrenal
  extracts or homeopathic hormones
A Systematic Nutritional Approach
To Clinical Disease Management
Specific Nutrients:
Neurotransmitter balance: chronic pain or psychogenic illness
  specific attention to neurotransmitter metabolism:
    Vit B6, Zn, Mg + Vit C & Fe
    Tryptophan or tyrosine to increase serotonin &
     dopamine respectively –
    DL-phenylalanine to increase endorphins
    Phosphatidylcholine & inositol to increase ACH
     levels
    Taurine & Glycine to decrease neurogenic
     activation
    Herbal therapy - Hypericum, Vervain, Valerian -
  A Systematic Nutritional Approach
  To Clinical Disease Management
Specific Therapy :
Hormone balance: the final step in regeneration is
 improving hormone balance & anabolic activity :
Nutrients - Vit C, Vit E & B5 –
Herbal therapy
     Adrenal - Eleutherococcus, Panax ginseng - Ginseng
      Oestrogen - Phytoestrogen, Vitex agnus, Dong Quai
     Testosterone - Serenoa, Pygeum, Tribulus -
Natural Hormone supplements :
  Pregnenelone, Natural Progesterone, DHEA
A Systematic Nutritional Approach
To Clinical Disease Management


              Many Thanks
          for your attendance,
           care and attention
     For further information and enquiries,
   speak to us at the RMIT University table or
       Email: Info@nutritionmedicine.org

				
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posted:3/24/2010
language:English
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