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34TH SEMDSA

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					        TH
      45          SEMDSA



             th
        14 NOFSA



 TH
13    DESSA WORKSHOP




     10 – 13 APRIL 2010


           DURBAN
                       CONTENTS


ACKNOWLEDGEMENTS


GUEST SPEAKERS


ORGANISING COMMITTEE


SOCIAL PROGRAMME


GENERAL INFORMATION


SCIENTIFIC PROGRAMME
SEMDSA WISH TO THANK THE FOLLOWING COMPANIES FOR THEIR
KIND SPONSORSHIP TOWARDS THE 2010 CONGRESS:

ABBOTT DIABETES CARE           SHARED TRIPLE STAND WITH SANOFI AVENTIS

ASTRA–ZENECA                   SINGLE STAND

BAYER DIABETES CARE            SHARED TRIPLE STAND WITH NOVO NORDISK

BD                             SINGLE STAND

BOEHRINGER INGELHEIM           2 X SINGLE STANDS

CIPLA MEDPRO                   DOUBLE STAND

ELI LILLY (SA) (PTY) LIMITED   DOUBLE STAND
                               SEMDSA BANQUET

HUMOR                          DOUBLE STAND

LIFESCAN INC                   SHARED TRIPLE STAND WITH NOVO NORDISK

MEDICAL BOOKS                  SINGLE STAND

MERCK (PTY) LTD                SINGLE STAND
                               PART SPONSORSHIP THEME EVENING

MSD                            2 x DOUBLE STANDS
                               OVERSEAS SPEAKER
                               PART SPONSORSHIP THEME EVENING

NOVARTIS                       DOUBLE STAND
                               OVERSEAS SPEAKER

NOVO NORDISK (PTY) LTD         SHARED TRIPLE STAND WITH LIFESCAN
                               2 X OVERSEAS SPEAKERS
                               2010 CONGRESS SECRETARIAT

PFIZER SA                      SINGLE STAND

ROCHE PRODUCTS                 DOUBLE STAND

SANDOZ SA (PTY) LTD            SINGLE STAND

SANOFI-AVENTIS                 SHARED TRIPLE STAND WITH ABBOTT
                               PART SPONSORSHIP OF THEME EVENING
                               NOFSA DINNER

SERVIER LABORATORIES           DOUBLE STAND
                               REGISTRATION DESK AND BAGS
                               2 X OVERSEAS SPEAKERS

SIEMENS                        SINGLE STAND

SOLVAY                         SINGLE STAND

VERTEC                         DOUBLE STAND
SEMDSA ALSO WISHES TO THANK ALL THE COMPANIES THAT PROVIDED LOCAL
       DELEGATES WITH SPONSORSHIP TO ATTEND THE CONGRESS
SEMDSA WISHES TO THANK THE FOLLOWING COMPANIES FOR THEIR
           GENEROUS SUPPORT OF THE SOCIETY:


SEMDSA FELLOWSHIPS
(This is an ongoing sponsorship per company for 6 years (2008 – 2013) and will enable 3 Clinical
Fellowships to be granted) – total value R432 000 per annum.

Eli Lilly SA (Pty) Limited
GlaxoSmithKline
Novo Nordisk (Pty) Limited
Novartis
Merck (Pty) Limited
Roche Diagnostics South Africa (Pty) Limited
Sanofi Aventis
Servier Laboratories

NOVO NORDISK FELLOWSHIP

Sole Fellowship for a Paediatric Endocrinologist to train for the period 2010/11 to the vaue of R432 000


SEMDSA/NOFSA AWARDS

Novo Nordisk Diabetes Travel Grant               R52 500
Novo Nordisk Diabetes Educators Grant            R36 750
Sanofi Aventis Travel Fellowship                 R50 000 (EASD CONGRESS SPONSORSHIP)
Sanofi Aventis Osteoporosis Award                R15 000



OTHER ANNUAL SPONSORSHIPS

SEMDSA Executive Travel Grant            Eli Lilly (SA) (Pty) Limited
SEMDSA Outreach Programme                Eli Lilly (SA) (Pty) Limited    R10 000 per annum + meeting
costs
Diabetes Update Symposium                Novo Nordisk (Pty) Ltd
SEMDSA Secretariat                       Novo Nordisk (Pty) Ltd
                     OVERSEAS GUEST SPEAKERS
                                SEMDSA


DAVID MATTHEWS
OXFORD CENTRE FOR DIABETES AND ENDOCRINOLOGY
CHURCHILL HOSPITAL
OXFORD
UNITED KINGDOM

KENNETH POLONSKY
DEPARTMENT OF MEDICINE
WASHINGTON UNIVERSITY SCHOOL OF MEDICINE
ST LOUIS
USA

PAUL STEWART
COLLEGE OF MEDICAL AND DENTAL SCIENCES
UNIVERSITY OF BIRMINGHAM
BIRMINGHAM
UNITED KINGDOM

GEOFFREY HACKETT
GOOD HOPE HOSPITAL
BIRMINGHAM
UNITED KINGDOM

                                 NOFSA


ROGER BOUILLON
CATHOLIC UNIVERISTY OF LEUVEN
LEUVEN
BELGIUM

JOHN EISMAN
UNVERSITY OF NEW SOUTH WALES & ST VINCENTS HOSPITAL
SYDNEY
AUSTRALIA


RENÉ RIZZOLI
DEPARTMENT OF BONE DISEASES AND GERIATRICS
GENEVA UNIVERSITY HOSPITALS AND FACULTY OF MEDICINE
GENEVA
SWITZERLAND

                                PAEDS-SA

STEVEN WAGUESPACK
DEPARTMENT OF ENDOCRINE NEOPLASIA & HORMONAL DISORDERS
DEPARTMENT OF PAEDIATRICS
UNIVERSITY OF TEXAS
USA
                 CONGRESS ORGANISING COMMITTEE


                           SEMDSA CONGRESS
                            ASLAM AMOD (CHAIRMAN)
                       HOOSEN RANDEREE (VICE CHAIRMAN)
                        THAVAN PADAYACHEE (SECRETARY)

                                AYESHA MOTALA
                               MOHAMMED OMAR
                                 FRASER PIRIE
                                 IMRAN PARUK
                                YASMEEN GANIE
                                MALIGAY NAIKER
                              SHAMEEN MAHABEER
                                 HAJRA BACUS
                                 SOPHIA RAUFF
                                 KUBEN PILLAY
                               SUREKA MAHARAJ
                              PREBASHINI NAIDOO


                            NOFSA CONGRESS
                         BILKISH CASSIM (CHAIRPERSON)
                                  ASLAM AMOD




                            DESSA WORKSHOP
                            LAURIE VAN DER MERWE




                        LOGGING OF CPD POINTS

        DISCOVERY WILL BE LOGGING THE CPD POINTS ON BEHALF OF SEMDSA.

YOUR NAME TAG WILL HAVE A BAR CODE AND THIS WILL BE SCANNED BY THE DISCOVERY AT
                 THE CPD DESK LOCATED OUTSIDE THE BALLROOM.
            SOCIAL PROGRAMME


              SATURDAY 10 APRIL 2010

             SEMDSA THEME EVENING
              MOSES MABIDA STADIUM
                      19:30
       BUSSES DEPART AT 18:30, 18:45 AND 19:00
        BUSSES RETURN AT 22:00, 22:30, 23:00

                SUNDAY 11 APRIL 2010

                 SEMDSA BANQUET
          GREAT ILLANGA, ELANGENI HOTEL
                      19:30

               MONDAY 12 APRIL 2010

                   NOFSA DINNER
                  SMALL ILLANGAS
                       19:30




                   SYMPOSIA

                 FRIDAY 9 APRIL 2010

                    08:00 – 17:00
            DIABETES UPDATE SYMPOSIUM
                  GREAT ILLANGA
           (SPONSORED BY NOVO NORDISK)


                SUNDAY 11 APRIL 2010

                  07:00 – 08:30
     SERVIER BREAKFAST WITH PROF MATTHEWS
                SMALL ILLANGAS

               MONDAY 12 APRIL 2010

                    07:00 – 08:30

PAEDS -SA BREAKFAST MEETING WITH PROF WAGUESPACK
               EAST/SOUTH ILLANGAS
           (SPONSORED BY NOVO NORDISK)
                            GENERAL INFORMATION

REGISTRATION                  FRIDAY 9 APRIL 2010             16:00   –   18::00
DESK:                         SATURDAY 10 APRIL 2010          07:00   –   17:00
                              SUNDAY 11 APRIL 2010            07:00   –   17:00
                              MONDAY 12 APRIL 2010            07:00   –   15:00



POSTER SESSION:               SATURDAY 10 APRIL 2010
                              FOYER AREA OF CONFERENCE CENTRE
                              ELANGENI HOTEL, DURBAN

LUNCHES:                      SERVED IN THE EXHIBITION AREA


SESSIONS:                     CONFERENCE CENTRE ELANGENI HOTEL


SLIDE PREVIEW ROOM:           AREA NEXT TO GREAT ILLANGA


DESSA WORKSHOP:               SATURDAY 10 APRIL 2010          08:30 – 17:00
                              NORTH ILLANGA


                                  MEETINGS



SEMDSA AGM:                               SATURDAY 10 APRIL 2010                   16:30 –
17:30
                                    GREAT ILLANGA

AWARDS COMMITTEE MEETING:           SATURDAY 10 APRIL 2010                17:30 – 18:00
                                    GREAT ILLANGA

DESSA AGM:                          SATURDAY 12 APRIL 2010                15:30 – 17:30
                                    NORTH ILLANGA


INDUSTRY MEETING:                   MONDAY 12 APRIL 2010                  07:00 – 08:00
                                    NORTH ILLANGA
            SCIENTIFIC PROGRAMME


              13TH WORKSHOP OF



THE DIABETES EDUCATION SOCIETY OF SOUTH AFRICA

                   (DESSA)
                     SATURDAY 10 APRIL 2010


09:00   WELCOME


09:15   Genetics in Type 2


09:45   Psychological Triggers and Stress
        Carol Dickson

10:15   Tea/Coffee

10:45   Nutritional Epigenomics of Metabolic Syndrome

11:15   Healthy Eating Guidelines
        Genevieve Jardine

11:45   Practicalities of increased Physical Activity
        Taz Chetty

12:15   DEBATE: Nature vs Nuture

13:00   Lunch

13:45   Supplementary and Complementary Therapies
        Silvana Nienaber

14:15   Laughter Therapy
        Suvashni Ramlochan

14:45   Close

15:00   Tea/Coffee

15:30   DESSA AGM

17:30   Close
          SCIENTIFIC PROGRAMME


          45TH CONGRESS OF THE

SOCIETY FOR ENDOCRINOLOGY, METABOLISM AND

        DIABETES OF SOUTH AFRICA

                (SEMDSA)
                         SATURDAY 10 APRIL 2010



08:35       OPENING ADDRESS
            NS Levitt, SEMDSA Chairperson

SESSION 1   08:45 – 10:15

            Chairpersons: Aslam Amod & Dinky Levitt

08:45       Insulin Resistance: A benefit more than a problem.
            David Matthews. Oxford Centre for Diabetes, Endocrinology
            and Metabolism, University of Oxford, United Kingdom.

09:30       Defects in gluteal adipogenesis are associated with obesity-related
            insulin resistance in black SA women.
            JH Goedecke, K Adams, P Hayes, J Evans, J Dave, NS Levitt,
            EV Lambert, SE Kahn, T Olsson. Medical Research Council,
            University of Cape Town and VAPSHCS/University of Washington,
            USA; Umeå University, Sweden.

09:45       Prevlance of the metabolic syndrome in HIV-Positive South Africans on
            anti-retroviral therapy.
            JA Dave, EV Lambert, NS Levitt. Division of Diabetic Medicine and
            Endocrinology and Division of Human Biology, University of Cape Town, Cape
            Town.

10:00       Bariatric surgery in a South African Bariatric Centre of Excellence: Pre-
            operative patient profiling in 315 patients.
            M-T van der Merwe, JH Pieters, A Maree, GK Fetter. Metabolic
            Medicine and Surgery Centre of Excellence, Sunninghil Netcare
            Hospital, University of the Witwatersrand and University of Pretoria.


10:15       Tea/Coffee

SESSION 2   10:45 – 12:00

            Chairpersons: Ayesha Motala and Nigel Crowther

10:45       The crucial role of 11ß-hydroxysteroid dehydrogenases and
            consequences for human disease.
            Paul M Stewart. College of Medical and Dental Sciences,
            University of Birmingham, Birmingham, United Kingdom.

11:30       Lipid content of different tissues of rats on a high fat diet and treated
            with metformin.
            S Roux, J MacKenzie, T Koekemoer, M van de Venter and G Dealtry. Nelson
            Mandela Metropolitan University, Department of Biochemistry and
            Microbiology, Port Elizabeth, South Africa
11:45       Ethnic differences in body composition cut points for
            predicting metabolic risk factors in South African women.
            J Evans, L Micklesfield, C Jennings, Y Joffe, NS Levitt, EV Lambert,
            T Olsson, JH Goedecke. University of Cape Town, University of
            Witwatersrand, Medical Research Council, South Africa. Umeå,
            Sweden.

12:00       Lunch

SESSION 3   13:00 – 13:45

            Meet the Professors

            Incretin therapies and the role of the gut in Type 2 diabetes:
            Hope or hype?
            Kenneth S Polonsky. Department of Medicine, Washington University
            School of Medicine, St Louis, USA.

            Cushing’s Syndrome and Adrenal incidentalomas.
            Paul Stewart. University of Birmingham, United Kingdom.

            How important is glycaemic control?
            David Matthews, Oxford Centre for Diabetes, Endocrinology
            and Metabolism, University of Oxford, United Kingdom



SESSION 4   13:45 – 14:45

            Poster Session

            Chairpersons: Roy Shires, Danie van Zyl & Julia Goedecke

            Clinical Endocrinology

P1          Experience with I131MIBG in two patients with carcinoid
            heart disease.
            C Weinreich, IL Ros, T Kotze, NS Levitt. Division of Endocrinology,
            Division of Nuclear Medicine in Department of Radiation Medicine,
            Groote Schuur Hospital, Cape Town.

P2          True hermaphroditism in a South African black adolescent.
            D Gordon, R Shires. Division of Endocrinology, Chris Hani
            Baragwanath Hospital and University of Witwatersrand,
            Johannesburg.

P3          Assessing math literacy skills in type 1 diabetic children and
            their caregivers.
            FY Moosa, D Segal. Department of Paediatrics, Chris Hani
            Baragwanath Hospital and Charolotte-Maxeke Johannesburg
            Academic Hospital, Johannesburg.
P4    Diabetic ketoacidosis in the medical wards of Dr G Mukhari Hospital.
      MC Mayayaise, MJ Mpe. Department of Internal Medicine,
      University of Limpopo-Medunsa Campus.


P5    Hyperglycaemic crisis: Clinico-laboratory features and
      outcomes of admissions for hyperosmolar versus non-
      hyperosmolar ketoacidosis.
      CO Ekpebegh. Walter Sisulu University/Nelson Mandela Academic
      Hospital, Mthatha.

P6    A patient with hypercalcaemia and a lung mass
      T Kemp ; J van Wyk ; B Ascott-Evans. Tygerberg Hospital, University of
      Stellenbosch.

      Basic Science

P7    The association of Apo CIII, Beta-3 adrenergic receptor and
      TNF-alpha polymorphisms with lipodystrophy in HIV-positive
      patients receiving anti-retroviral therapy.
      TF Tlomatsana, NH Naran & NJ Crowther. Department of Chemical
      Pathology, NHLS and the University of Witwatersrande, Johannesburg.

P8    Increased fatty acid supply induces the hexosamine biosynthetic
      pathway in heart cells.
      R Harris, MF Essop. Department of Physiological Sciences,
      Stellenbosch University, Stellenbosch.

P9    Increased hexosamine biosynthetic pathway flux upregulates
      myocardial acetyl-CoA gene expression.
      J Imbriolo, MF Essop. Department of Physiological Sciences,
      Stellenbosch University, Stellenbosch.

P10   Increased hexosamine biosynthetic pathway flux leads         to
      PKB/AKT post-translational modification: Implications for onset of
      insulin resistance.
      D Joseph, MF Essop. Department of Physiological Sciences,
      Stellenbosch University, Stellenbosch.

P11   The expression of the tumour suppressor Pdcd$ in 3t3-L1
      pre-adipocytes and adipose-derived stromal/stem cells.
      M van den Heever, CU Niesler, FS Hough, WF Ferris. Department
      of Medicine, Stellenbosch University, Tygerberg. Department of
      Biochemistry, University of KwaZulu-Natal, Pietermaritzburg.


P12   Efficacy of Prunus Africana bark extract and metformin in
      the treatment of high fat diet induced fatty liver.
      SC Tshidino, J Karachi, T Koekemoer, S Roux. Nelson Mandela Metropolitan
      University, Department of Biochemistry and Microbiology, Port Elizabeth.

P13   In Vitro safety and efficacy assessment of the anti-diabetic
      Medicinal plant: Sutherlandia Frutescens.
            T Koekemoer, M van de Venter and S Roux. Nelson Mandela Metropolitan
            University, Department of Biochemistry and Microbiology, Port Elizabeth.

P14         In Vitro assessment of the interaction between African
            Medicinal plants and anti-diabetic prescription medicines.
            C Fang, T Koekemoer and S Roux. Nelson Mandela Metropolitan
            University, Department of Biochemistry and Microbiology,
            Port Elizabeth.

P15         The regenerative capacity of pancreatic tissue following an 80-90%
            partial pancreatectomy in a wistar rat.
            S Ghoor, C Muller, C Pheiffer, D du Toit, BJ Paige. Medical Research
            Council, University of Stellenbosch.

14:45       Tea/Coffee

SESSION 5   15:15 – 16:30

            Chairpersons: Fraser Pirie and Paul Rheeder

15:15       What have we learned from genetic studies of type 2 diabetes?
            Kenneth Polonsky, Department of Medicine, Washington
            University School of Medicine, St Louis, USA.

16:00       An in vitro study of the effects of free fatty acids on glucose metabolism
            in myocytes and fibroblast derived adipocytes.
            SE Mazibuko, CJF Muller, C Pheiffer, J Louw and A Opoku. Diabetes
            Discovery Platform, Medical Research Council of South Africa, Tygerberg,
            and Department of Biochemistry and Microbiology, University of Zululand.

16:15       Mitogenic and lipogenic actions of insulin on cultured adipose-derived
            stromal cells.
            H Sadie-Van Gijsen, N Crowther, FS Hough, W Ferris. Dept of Medicine,
            University of Stellenbosch and Dept of Chemical Pathology, NHLS, University
            of Witwatersrand

16:30       SEMDSA Annual General Meeting

17:30       SEMDSA Awards Committee Meeting
                             SUNDAY 11 APRIL 2010


SESSION 6    09:00 – 10:30

             Chairpersons: Hoosen Randeree & Larry Distiller


09:00        Testosterone, erectile dysfunction and type 2 diabetes.
             Geoffrey Hackett. Good Hope Hospital, Sutton Coldfield, Birmingham,
             United Kingdom.

09:45        Cross-sectional associations with carotid intima media thickness (imt)
             in patients with type 2 diabetes mellitus seen at Kalafong hospital.
             MC Duim Beytell, P Rheeder, R Meijer, T Gustavsson
             GKG Danler, RA Ahmed, DG Van Zyl. University of Pretoria, Meijer Medical
             Ultrasound,Netherlands and Image and Data Analysis Company, Sweden

10:00        Outcome data in bariatric surgery: A South African
             experience of 261 patients.
             GK Fetter, JH Pieters, A Maree, M-T van der Merwe. Metabolic
             Medicine and Surgery Centre of Excellence, Sunninghill Hospital,
             University of Witwatersrand, University of Pretoria.

10:15        Tea/Coffee

SESSION 7:   10:45-12:00

             Chairpersons: Roy Shires and William Ferris

10:45        WPU JACKSON MEMORIAL LECTURE
             The role of the pancreatic ß-cell in type 2 diabetes: Culprit
             or bystander?
             Kenneth Polonsky. Department of Medicine,
             Washington University of Medicine, ST Louis, USA.

11:30        Post-Transcriptional silencing of the Tissue Non-Specific
             Alkaline Phosphatase (TNSALP) gene blocks intracellular
             lipid accumulation in a murine predipocyte cell line, 3T3-L1
             and in a human hepatocarcinoma cell line, HepG2.
             GM Chirambo, C van Niekerk and NJ Crowther. Department of
             Chemical Pathology, NHLS, University of Witwatersrand,
             Johannesburg.

11:45        Association of the platelet glycoprotein IIIa PIA1/A2 polymorphism with
             body mass index (BMI).
             NH Naran, NJ Crowther. Department of Chemical Pathology,
             NHLS, University of Witwatersrand, Faculty of Health Sciences,
             Johannesburg.

12:00        Lunch
SESSION 8   13:00 – 13:45


            Meet the Professors

            Incretin therapies and the role of the gut in Type 2 diabetes:
            Hope or hype?
            Kenneth Polonsky. Department of Medicine, Washington University
            School of Medicine, St Louis, USA.

            Cushing’s Syndrome and Adrenal incidentalomas.
            Paul M Stewart. University of Birmingham, United Kingdom.

            Endocrine consequences of childhood malignancies.
            Steven G Waguespack.
            Department of Endocrine Neoplasia & Hormonal
            Disorders, University of Texas MD Anderson Cancer Centre,
            Houston.


SESSION 9   13:45 – 15:00

            Chairpersons: Kuben Pillay and Yasmeen Ganie


13:45       Thyroid malignancies in children and young adults: Current
            Approaches to diagnosis and treatment.
            Steven Waguespack. Department of Endocrine Neoplasia
            and Hormonal Disorders, University of Texas MD Anderson
            Cancer Centre, Houston.

14:30       Ringer’s lactate versus saline for resolution of acidosis in
            diabetic ketoacidosis: a randomized controlled trial. Preliminary
            results.
            DG van Zyl, P Rheeder, E Delport. Department of Internal Medicine and
            Division of Clinical Epidemiology, University of Pretoria, Pretoria.

14:45       Monitoring of replacement therapy in patients with Addison’s
            Disease, using salivary cortisol day curve measurements.
            I Ross, NS Levitt, JS van der Walt, TS Pillay. Division of
            Endocrinology and Department of Medicine, Division of Clinical
            Pharmacology, Division of Chemical Pathology, University of Cape
            Town, Cape Town.


15:00       Tea/Coffee
SESSION 9   15:30 – 16:45

            Chairpersons: Willie Mollentze and Jacobus van Dyk

15:30       Recent advances in endocrine hypertension.
            Paul M Stewart. College of Medical and Dental Sciences,
            University of Birmingham, Birmingham, United Kingdom.

16:15       Characteristics, management and outcomeof patients with
            Primary hyperparathyroidism referred to Inkosi Albert Luthuli Central
            Hospital between 2003 and 2009.
            I Paruk, FJ Pirie, S Maharaj, A Motala. Department of Diabetes and
            Endocrinology, Inkosi Albert Luthuli Hospital/University of Kwa Zulu
            Natal, Durban.

16:30       Predicting periperhal vascular disease: Is B2 microglobuin of any
            value?
            P Rheeder, FO Meeuwes, M van Schendel. Department of Internal Medicine
            and Division of Clinical Epidemiology, University of Pretoria, Pretoria.
                          MONDAY 12 APRIL 2010


SESSION 10   09:00 – 10:30

             Chairpersons: Mahommed Omar & Magda Conradie

09:00        THE BERNARD PIMSTONE MEMORIAL LECTURE
                                                             st
             Type 2 diabetes: The “black death” of the 21 century
             David Matthews. Oxford Centre for Diabetes, Endocrinology
             and Metabolism, University of Oxford, United Kingdom.

09.45        Factors determining waist circumference thresholds in white
             women and black women of different ancestries.
             JH Goedecke, LK Micklesfield, J Evans, M Ricks, AV Tambay, NA Avila,
             F Thomas, MK Tulloch-Reid, AE Sumner. Medical Research Council,
             University of Cape Town, University of the Witwatersrand, South Africa.
             National Institutes of Health, Washington DC Veterans Affairs Medical
             Centre, USA, Uinversity of the West Indies, Jamaica.

10.00        The relationship between national socio-economic variables and
             obesity prevalence rates in Africa and Europe.
             AT Ali, NJ Crowther. Department of Chemical Pathology, NHLS,
             University of the Witwatersrand, Faculty of Health Sciences,
             Johannesburg.

10.15        The prevalence and trend of diabetes mellitus in urban Africans in
             Cape Town from 1990 to 2008/9.
             N Peer, , NS Levitt, K Steyn, N Gwebushe, K Bobrow, C Lombard.
             MRC CDL Research Unit, UCT. Department of Medicine, MRC
             Biostatistics Unit, Cape Town.


10:30        Tea/Coffee

SESSION 11   11:00 – 12:30

             Chairpersons: Bilkish Cassim & Ken Huddle

11:00        Hyperparathyroidism: a diagnostic and therapeutic challenge.
             R Bouillon. Department of Experimental Medicine-Endocrinology,
             Catholic University of Leuven(K.U Leuven), Belgium.

11.45        National Guideline for the diagnosis and management of
             osteoporosis (OP).
             FS Hough, B Ascott-Evans, S Brown, B Cassim, T de Villiers, S
             Lipschitz, J Pettifor and E Sonnendecker for the National Osteoporosis
             Foundation of South Africa (NOFSA)
12.30   Lunch
          SCIENTIFIC PROGRAMME

           14TH CONGRESS OF THE

NATIONAL OSTEOPOROSIS FOUNDATION OF
           SOUTH AFRICA


               (NOFSA)
                                  MONDAY 12 APRIL 2010


SESSION I           11:00 – 12:30

                    Chairpersons: Bilkish Cassim & Ken Huddle

11:00               Hyperparathyroidism: a diagnostic and therapeutic challenge.
                    R Bouillon. Department of Experimental Medicine-Endocrinology,
                    Catholic University of Leuven(K.U Leuven), Belgium.

11.45               National Guideline for the diagnosis and management of
                    osteoporosis (OP).
                    FS Hough, B Ascott-Evans, S Brown, B Cassim, T de Villiers, S
                    Lipschitz, J Pettifor and E Sonnendecker for the National Osteoporosis
                    Foundation of South Africa (NOFSA)

12.30               Lunch

SESSION II          13:30 – 15:15

                    Chairpersons: John Pettifor & Tobie de Villiers

13:30               Assessment of bone density and microstructure with special
                    Reference to children and adolescents.
                    R Rizzoli. Division of Bone Diseases, Department of
                    Rehabilitation and Geriatrics, Geneva University Hospitals and
                    Faculty of Medicine, Geneva, Switzerland.

14:15               Ethnic differences in DXA and PQCT measures between South
                    African children aged 13 years.
                    LK Micklesfield, SA Norris, JM Pettifor.
                    MRC Mineral Metabolism Research Unit, Department of Paediatrics
              University of Witwatersrand, Johannesburg; ESSM, Department of
                    Human Biology, University of Cape Town, Cape Town.

14:30               Heterogeneity in fracture pathogenesis in urban South African
                    children: the birth to twenty cohort.
                    K Thandrayen, SA Norris, LK Micklesfield, JM Pettifor. MRC Mineral
                    Metabolism Research Unit, Department of Peadiatrics, University of
                    Witwatersrand, Johannesburg.

15:00               Tea/Coffee

SESSION III         15:30 – 17:00

                    Chairpersons: Stephen Hough & Kebashni Thandrayen

15:30               Osteoporosis epidemiology: Fracture, subsequent fracture and
                    premature mortality.
        J Eisman, Garvan Institute of Medical Research, University of New
        South Wales and St Vincent’s Hospital, Sydney, Australia.

16:15   Exercise and Bone
        LK Micklesfield. MRC Mineral Metabolism Research Unit, Department
        of Paediatrics, University of the Witwatersrand.

16:45   Audit of DXA scans at Groote Schuur Hospital between 2007-2010
        from Departments of Gastroenterology and Endocrinology.
        AA Kalla, L Bewerunge, AB Fataar. Departments of Medicine and
        Nuclear Medicine, University of Cape Town, Cape Town.
                  TUESDAY 13 APRIL 2010


SESSION IV   08:30 – 10:30

             Chairpersons: Sue Brown & Magda Conradie

08:30        Dietary Protein and Bone: Devil or Angels?
             R Rizzoli. Division of Bone Diseases, Department of
             Rehabilitation and Geriatrics, Geneva University Hospitals
             and Faculty of Medicine, Geneva, Switzerland.

09:15        Differentiating adipose-derived stromal cells (ADSCs) into
             Osteoblasts: Not all ADSCs are created equal.
             H Sadie-van Gijsen, W Smith, EF du Toit, FS Hough, WF Ferris.
             Department of Medicine, University of Stellenbosch. Department
             of Biomedical Sciences, University of Stellenbosch.

09:35        Glucocorticoids up-regulate MKP-1 and inhibit proliferation
             in naïve mesenchymal stromal cells and primary pre-
             osteoblasts.
             M Sanderson, H Sadie-van Gijsen, FS Hough and WF Ferris.
             Department of Medicine, University of Stellenbosch.

10:05        Tea/Coffee

SESSION V    10:30 – 12:30

             Chairpersons: Ernie Sonnendecker & Shane Norris

10:30        Vitamin D is a multifunctional hormone: lessons from
             transgenic mice.
             R Bouillon. Department of Experimental Medicine-
             Endocrinology, Catholic University of Leuven(K.U Leuven),
             Belgium.

11:15        Longitudinal assessment of Vitamin D status in urban
             South African children.
             MA Poopedi, SA Norris, JM Pettifor. MRC Mineral Metabolism
             Research Unit, Birth to Twenty Research Programme, University
             of Witwatersrand, Johannesburg.

11:30        Vitamin D status of mothers and their newborns in Soweto.
             H Ranchod, SA Norris, JM Pettifor. MRC Mineral Metabolism
             Research Unit, Birth to Twenty Research Programme, University
             of Witwatersrand, Johannesburg.
11:45        Vitamin D and calcium requirements during pregnancy and
             lactation.
             JM Pettifor. Department of Paediatrics, Chris Hani Baragwanath
             Hospital, University of the Witwatersrand, Johannesburg.

12:15        Lunch

SESSION VI   13:15 – 15:30

             Chairpersons: Stephen Hough & William Ferris

13:15        Osteoporosis Treatment: Who to Treat? When to start?
             When to stop?
             J Eisman. Garvan Institute of Medical Research, University
             of New South Wales and St Vincent’s Hospital, Sydney,
             Australia.

14:00        An update on the promise of SERMS.
             T de Villiers. Cape Town

14:30        HIV and Osteoporosis.
             S Brown. Department of Medicine, University of Witwatersrand,
             Johannesburg.

15:00        Prevalence of low bone mineral density in HIV-positive South
             Africans on anti-retroviral therapy.
             J Dave. Department of Medicine, University of Cape Town,
             Cape Town.

15:15        Close

				
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