The Immune System
By: Matt Soto
Recognizes Things That Are Foreign Fungus Bacteria
Virus
http://www.earthlife.net/prokaryotes/images/bacteria.gif ttp://www.sciencenetlinks.com/images/interactive/fungi.jpg
Pollen
http://asm.wku.edu/pix/cells/virus.gif
Parasite(Worm)
http://www.acs.ohio-state.edu/researchnews/archive/pollen.gif
http://www.microbe.org/art/tapeworm.jpg
Where Is It?
Lung Skin
http://remf.dartmouth.edu/images/mammalianLungSEM/image/1lungsem.jpg http://www.sghms.ac.uk/depts/em/galleries/4_pathogens/images_big/sknbac.jpg
EVERYWHERE!!!!
Blood Liver
http://www.ualberta.ca/~cw9/labtour/hem.html
http://www.forschung3r.ch/de/publications/bu26.html
Components
Innate System
Acquired System
Innate System
Primative Every animal has this 1st line of defense Gets activated within minutes
Innate System
Types of Cells
– Granulocytes – Mast – Macrophages – Natural Killer Cells – Dendritic
Basophil
Neutrophil
Granulocytes
http://www.geocities.co.jp/BeautycareVenus/3423/basophil.jpg http://www.hoslink.com/images/neut2web.jpg
Heterophil Eosinophil
http://www3.umdnj.edu/histsweb/lab5/images/eosinophil. jpg
http://www.science.uwc.ac.za/zoology/Staff/retha/_borders/Het erophil_and_red_cells.jpg
Granulocytes
Come from Bone Marrow Contain Granules Involved in inflammation (neutrophils/heterophils) Allergy (Basophil & Eosinophil) Anti-parasite (Eosinophil
Mast
http://pathology.mc.duke.edu/research/histo_course/mastcell_em2.jpg
Mast
Evolves from Granulocytes Works as anti-body receptor Very involved in allergy responses
Macrophage
http://www.thecrookstoncollection.com/Collection/medslides/Slides/ Macrophage-01.jpg
http://immuneweb.xxmc.edu.cn/pic/Alveolar%20Macrophage%20attacking%2 0E.%20coli2.jpg
Macrophage
Very long life cycle Major Functions
– Phagocytosis
– Protein synthesis
– Wound healing – Activates acquired immune system
Dendritic
http://www.wehi.edu.au/cytometry/images/JV28110023and24.jpg
Dendritic
Very similar to macrophage Phagocytosis Very important in acquired immune activation
Natural Killer
http://www.sirinet.net/~jgjohnso/killertcells.jpg
Natural Killer
Involved with anti-cancer activity Not much known on origin or other factors
Phagocytosis
•Get to the antigen •Bind to the antigen •Engulf antigen •Destroy antigen
Phagocytosis
Involves getting to the antigen, binding to it, engulfing it,
Then destroying it
Check Out Cells Alive Clip: http://www.cellsalive.com/mac.htm
Innate & Acquired Immune System
NEXT TIME
Acquired
Innate
DONE