REM 445-3

                                                 Dr. Frank Gobas
                          School of Resource & Environmental Management

The objective of this course is to provide students with theory and practical experience
in the area of applied environmental toxicology. The course will cover (i) theoretical
principles of environmental distribution and toxicity of pollutants, (ii) practical techniques
for the assessment of the environmental behaviour, toxicity and ecological & human
health risks of contaminants in the environment, and (iii) a critique of current
environmental management practices in Canada. Students apply these techniques in a
class project. The course material is essential for those expecting to be involved in
pollution-related issues.


1. ENVIRONMENTAL BEHAVIOUR OF CHEMICALS: environmental partitioning,
kinetics of environmental distribution, mass balance, mechanisms of transport &
transformation, fugacity, environmental modeling

2. EXPOSURE ASSESSMENT: mechanisms of chemical uptake & elimination in
organisms, bioaccumulation, trophic transfer and biomagnification, structure-activity

3. HAZARD & EFFECTS ASSESSMENT: toxicity of chemical pollutants in organisms,
dose-response relationships, toxicity of mixtures of chemicals, ecotoxicity,

4. RISK ASSESSMENT: risk quotients, quantitative and probabilistic risk assessment

5. CONTAMINANT MANAGEMENT: application of scientific principles in current
environmental management practices and regulations in Canada, development of
standards & human consumption guidelines, environmental quality criteria, monitoring,
risk assessment, effluent regulations and others

FORMAT: One lecture and one tutorial per week. Tutorials include computer labs and
group discussions.
SCHEDULE: Thursday, 10:30 - 12:20 (lecture) in AQ5005 and Thursday, 1:30 - 2:20 -
Catalog #1817- (tutorial)

EVALUATION: Students are evaluated based on assignment #1 (25% of the final mark),
assignment #2 (30%), 1 student paper/poster presentation (35%) and class contributions

READINGS: All readings will be handed out on the first day of classes. All class
overheads will be made available in electronic format on the first day of classes.

OFFICE HOURS: Mondays 10:30 – 12:30 am.

FOR MORE INFORMATION CALL: 778-782-5928. If you encounter any problems
registering for the course, please let me know. This seems to happen now and then.

                              Tentative REM 445 Class Schedule

All Lectures in AQ5005. All Tutorials in xxxx.

 Date         Tentative Topic to be Discussed      Preparation for this class/Practicum
 Week 1       Lecture: Introduction: Course        Cairns.pdf (Voluntary)
              Outline & rationale
              Course Content, Marking, logistics
              Overheads: 610-1.ppt
              Tutorial: Introduction
 Week 2       Lecture: Canadian Environmental      Toxic Substances Management Policy. Cat. No. En 40-
              Protection Act Toxic Substances      499/1-1995. Min. of Supply and Services. Ottawa, ON.
              Management Policy.                   http://www.ec.gc.ca/CEPARegistry/default.cfm
              Management of Contaminants           CEPA act.pdf
              Tutorial: Discuss Canadian           Toxic Substances Management Policy. Cat. No. En 40-
              Environmental Protection Act Toxic   499/1-1995. Min. of Supply and Services. Ottawa, ON.
              Substances Management Policy.        http://www.ec.gc.ca/CEPARegistry/default.cfm
                                                   CEPA act.pdf
 Week 3       Lecture: Chemicals & their           Multi-Media: 2.1, 2.2, 3.1-3.4,
              environmental properties
              Overheads: 610-3.ppt
              Tutorial: Chemicals & their          Multi-Media: 2.1, 2.2, 3.1-3.3,
              environmental properties:
              • Demonstration Environmental
                 Fate DataBase
              • Start Hazard Evaluation
                 Exercise 1
              • Questions
              Answers: 610-ex1.ppt
Week 3   Lecture: Multi-media                Multi-Media: 2.3, 2.4, 4.1-4.7, 5.1, 5.2, 5.3.1,
         Environmental Fate                  5.3.3, 5.3.4, 5.4-5.6.2, 5.6.6-5.9
         Overheads: 610-4.ppt
         Tutorial: Environmental Fate        Complete Exercise 1
         • Questions
         • Discuss Results Exercise 1
         • Start Exercise 2
         Answers: 610-ex2.ppt
Week 4   Lecture: Reaction & Transport       Multi-Media: 2.4.2-2.8, 6.1-6.9
         Overheads: 610-5.ppt
         Tutorial: Reaction & Transport:     Complete exercise 2
         • Questions
         • Discuss MM2,7 &2.12
         • Discuss exercise 2
         • Start Exercise 3
         • Paper Discussion
         Answers: 610-ex3.ppt
Week 5   Lecture: Environmental Fate         Multi Media:7.1-7.3, 7.8-7.12,8.1-8.3, 8.5-8.8
         Models                              Websterpersistence.pdf
         Overheads: 610-6a.ppt, 610-6b.ppt
         Tutorial: Environmental Fate        Complete exercise 3
         models: Practicum
         • Questions
         • Demonstration of ChemCan3
         • Discuss Exercise 3
         • Paper Discussion
         Answers: 610-ex3.ppt
Week 6   Lecture: Chemical Toxicity          McCarty.pdf
         Handout assignment #1               Review of pharmacological concepts.pdf
         Overheads: 610-7a.ppt, 610-7b.ppt   SETACglobe.pdf
         Tutorial: Chemical Toxicity :
         • Questions
         • Start Exercise 4
         • Paper Discussion
         Answers: 610-ex4.ppt
Week 7   Lecture: Hazard Assessment &        Fish consumption *.pdf
         Risk Assessment                     (EPA-503/8-89-002)
         Overheads: 610-7b.ppt,
         Tutorial: Hazard & Risk             Complete exercise 4
         Assessment: Practicum
         • Questions
         • Discuss Exercise 4
         • Start Exercise 4B, 7
         Answers: 610-ex7.ppt
Week 8    Lecture: Bioaccumulation & Food-    Woodwell.pdf
          chain transfer                      Connell.pdf (voluntary)
                                              Gobas.pdf (voluntary)
                                              Mackay 1982.pdf
          Overheads: 610-8a.ppt, 610-8b.ppt   Pedersen & Connolly.pdf
                                              Gobas Zhang Wells.pdf or
                                              Gobas Wilcockson.pdf
          Tutorial: Bioaccumulation           Complete exercise 4B
          • Questions
          • Discuss Exercise 4B
          • Start Exercise 5
          Answers: 610-ex5.ppt
Week 9    Lecture: Environmental Criteria     Protocol water quality guidelines.pdf
          Development                         Water quality guidelines.pdf
          Hand out Credit Assignment #2       Protocol for sediment quality guidelines.pdf
          Overheads: 610-10.ppt
          Tutorial:                           Complete Exercise 5
          • Assignment #1 Discussion,
          • Questions
          • Discuss Exercise 5
          Answers: 610-ex6.ppt
Week 10   Lecture: Ecological Risk            Ecorisk.pdf
          Overheads: 610-9.ppt
          Credit Assignment #2 is due
          Tutorial: Ecological Risk
          Assessment: Practicum
          • Questions
          • Start Exercise 6
          Answers: 610-ex6.ppt
Week 11   Lecture: Student Presentations      Student Presentations
          Tutorial: Ecological Risk           Complete Exercise 6
          Assessment: Practicum
          • Questions
          • Discuss Exercise 6
          Answers: 610-ex6.ppt
Week 12   Lecture: Discuss Credit             Final Questions
          Assignment #2
          •  Final Questions
          •  Wrap up + evaluation
          Tutorial: Student Presentations     Student Presentations

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