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Research Profile Professor Bill Shaw

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					Research Profile
Professor Bill Shaw
Personal Background
I graduated in Dentistry from the University of Glasgow in 1968 and ob-
tained a Fellowship in Dental Surgery and a Diploma in Orthodontics in
1971 and 1972 respectively. I obtained a Masters degree in Dental Science
1976 and a PhD in 1980 both from the University of Wales.
I joined the University of Manchester, School of Dentistry in 1983 where I hold
the post of Professor in Orthodontics and Dentofacial Development.

Research Group:
Craniofacial Anomalies & Orthodontics
Craniofacial Anomalies Research
Our craniofacial unit coordinates a European collaborative research
programme on cleft lip and palate and related anomalies that includes
randomised trials of surgery, a prospective cohort study of facial bone
elongation (distraction osteogenesis), intercentre comparisons of surgical
outcome for cleft surgery, the relationship of genetic and environmental
factors in the causation of cleft lip and palate, and gene discovery studies
(www.eurocran.org).
                                                                             Scandcleft Project: Randomised control trial
We also lead a related initiative for the World Health Organisation (www. of primary surgery in unilateral cleft lip and
who.int/genomics/anomalies/cfaproject) and are the WHO’s only desig- palate.
nated centre for research on the treatment of craniofacial anomalies.
We have recently completed an international randomised trial of surgery
for velopharyngeal incompetence (speech impairment) for children with
repaired cleft palate and defined the optimal feeding techniques for
children with clefts. The Scandcleft Trial, a randomised trial of primary
surgery for unilateral cleft lip and palate, co-ordinated by Gunvor Semb,
has recently enrolled the intended sample of 450 infants across Scandi-
navia and the UK.
Papers of Interest
  Abyholm F; Antonio L; Davidson, SL; Kjoll L; Saeed M; Shaw, WC; Semb, G;
  Worthington, HV. VPI Surgical Trial Group. Pharyngeal flap and sphinc-
  terplasty for velopharyngeal insufficiency have equal outcome at 1 year
  postoperatively: results of a randomized trial. Cleft Palate-Craniofacial 3D surface laser scanned images of study
  Journal, 2005; 42: 501-511 .                                              casts superimposed on the palatal mucosa to
                                                                            measure tooth movement.
  Semb G, Brattström V, Mølsted K, Prahl-Andersen B, Shaw WC. The
  Eurocleft Study. Intercenter study of treatment outcome in patients
  with complete cleft lip and palate. Part 1: Introduction and treatment
  experience. Cleft Palate-Craniofacial Journal. 2005; 42: 93-99.
  Shaw WC, Brattström V, Mølsted K, Prahl-Andersen B, Roberts CT, Semb G.
  The Eurocleft Study. Longitudinal follow-up of patients with complete
  unilateral cleft lip and palate. Part 5: Discussion and Conclusions. The
  Cleft Palate-Craniofacial Journal. 2005; 42: 64-68
  Shaw WC, Semb G, Nelson P, Brattström V, Mølsted K, Prahl-Andersen
  B, Grunlach KKH. The Eurocleft Project 1996-2000: Overview Journal              Fixed functional Twin Block appliance as used
  of Cranio-Maxillofacial Surgery, 2002; 29: 131-140.                             in a clinical trial.




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  Glenny AM, Hooper L, Shaw WC, Reilly S, Kasem S, Reid J. Feeding interventions for growth and development
  in infants with cleft lip, cleft palate or cleft lip and palate. The Cochrane Database of Systematic Reviews,
  2004; Issue 3.
  Mohlin BO, Derweduwen K, Pilley R, Kingdon A, Shaw WC, Kenealy P. Malocclusion and temporomandibular
  disorder: a comparison of adolescents with moderate to severe dysfunction with those without signs and
  symptoms of temporomandibular disorder and their further development to 30 years of age. Angle Ortho-
  dontist, 2004; 319-27.
  Bearn DR, Mildinhall S, Murphy T, Murray JJ, Sell D, Shaw WC, Williams AC, Sandy JR. Cleft Lip and Palate Care
  in the United Kingdom (UK) – The Clinical Stanards Advisory Group (CSAG) Study: Part 4 – Outcome compari-
  sons, training and conclusions. Cleft Palate-Craniofacial Journal, 2001; 38:1:38-43.
Orthodontics Research
The orthodontic research unit, directed by Professor Kevin O’Brien undertakes clinical trials of a range of ortho-
dontic interventions. Recent multicentre trials, sponsored by the Medical Research Council (UK) have provided
new insights into treatment timing, and dental and psychological outcomes. The unit is presently publishing
reports on a twenty year longitudinal study of the effectiveness of orthodontic treatment.
Our research is funded by the Medical Research Council (UK), NIDCR, the European Commission and the Depart-
ment of Health (UK).
Papers of Interest
  O’Brien KD, Wright JL, Conboy FM, Sanjie Y, Mandall NA, Chadwick S, Connolly I, Cook P, Birnie D, Hammmond M,
  Harradine N, Leiws D, McDade C, Mitchell L, Murray A, O’Neill J, Read M, Robinson S, Roberts-Harry D, Sandler J,
  Shaw I. Effectiveness of early orthodontic treatment with the Twin-block appliance: a multicenter, randomized,
  controlled trial. Part 1: Dental and skeletal effects. American Journal of Orthodontics, 2003; 124(3):234-243.
  O'Brien, KD; Wright, JL; Conboy, FM; Chadwick, S; Connolly, I; Cook, P; Birnie, D; Hammond, M; Harradine, N; Lewis,
  D; McDade, C; Mitchell, L; Murray, A; O'Neill, J; Read, M; Robinson, S; Roberts-Harry, D; Sandler, J; Shaw, I; Berk, N. Ef-
  fectiveness of early orthodontic treatment with the Twin-block appliance: a multicenter, randomized, controlled
  trial. Part 2: Psychosocial effects. American Journal of Orthodontics, 2003; 124(5):488-494.
  Kenealy, P.M., Kingdon, A., Richmond, S. & Shaw, W.C. (2007). The Cardiff dental study: A 20-year critical evalu-
  ation of the psychological health gain from orthodontic treatment. British Journal of Health Psychology, 12,
  17-49.
  O'Brien, KD; Wright, JL; Conboy, FM; Sanjie, Y; Mandall, NA; Chadwick, S; Connolly, I; Cook, P; Birnie, D; Hammond,
  M; Harradine, N; Lewis, D; McDade, C; Mitchell, L; Murray, A; O'Neill, J; Read, M; Robinson, S; Roberts-Harry, D;
  Sandler, J; Shaw, I. Effectiveness of treatment for Class II malocclusion with the Herbst or twin-block appli-
  ances: a randomized controlled trial. American Journal of Orthodontics, 2003; 124(2):128-137.
  Mandall NA, Lowe C, Worthington HV. Index of Orthodontic Treatment Need as a predictor of orthodontic
  treatment uptake. American Journal of Orthodontics, 2005; 128:703-707.
  Mandall NA, O’Brien KD, Brady J, Worthington HV, Harvey L. Teledentistry for screening new patient ortho-
  dontic referrals. Part 1: A randomized controlled trial. British Dental Journal, 2005; 199:659-662.
  Usmani T, O’Brien KD, Worthington HV, Derwent S, Fox D, Harrison S, Sandler RJ, Mandall NA. A randomized
  clinical trial to compare the effectiveness of canine lacebacks with reference to canine tip. Journal of Ortho-
  dontics, 2002; 29: 281-286.
  Robinson PG, Deacon SA, Deery C, Heanue M, Walmsley AD, Worthington HV, Glenny AM, Shaw WC. Manual
  versus powered tooth brushing for oral health. Cochrane Review, Oxford Update Software, 2003.




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