Docstoc

GNT_CV

Document Sample
GNT_CV Powered By Docstoc
					CURRICULUM VITAE


NAME:                      THOITHI

OTHER NAMES:               GRACE NJERI

NATIONALITY:               KENYAN

PRESENT POSITION:         ASSOCIATE PROFESSOR AND CHAIRMAN,
                          DEPARTMENT OF PHARMACEUTICAL CHEMISTRY,
                          FACULTY OF PHARMACY
                          UNIVERSITY OF NAIROBI

A. CONTACT INFORMATION

Address (office)           Department of Pharmaceutical Chemistry
                           Faculty of Pharmacy,
                           University of Nairobi,
                           P. O. Box 19676-00202,
                           Nairobi.

Address (private)          P. O. Box 19902-00202,
                           Nairobi.

Telephone (office)         254-20-2716962
Telephone (mobile)         0722-780302
Fax                        254-20-2716961
e-mail                     gthoithi@uon.ac.ke
                           gnthoithi@yahoo.com

B. EDUCATION

1992 - 1996                Doctor of Pharmaceutical Sciences
                           Katholieke Universiteit Leuven

1990 - 1992                Master of Pharmaceutical Sciences
                           Katholieke Universiteit Leuven

1981 - 1986                Bachelor of Pharmacy degree
                           University of Nairobi


C. UNIVERSITY EMPLOYMENT

1988-Date   University of Nairobi.
D. PROJECT FUNDING




                                                                    1
1. Project Title: In vitro testing of Kenyan medicinal plants for anthelmintic activity (F/3010-1).
   Investigator: Grace N. Thoithi
   Funding agent: International Foundation for Science (IFS), Sweden.
   Period: 2000-2001

2. Project Title: Evaluation of medicinal plants for anthelmintic activity (ARF/LSKP/1001078/1)
   Principal Investigator: Peter Gathumbi, Principle Co-investigator: Grace N. Thoithi
   Funding agent: Agricultural Research Fund (ARF), Kenya
   Period: 2000-2003. Won Third National Scientific Award.

3. Project Title: Evaluation of extracts from selected medicinal plants in Kenya for anthelmintic
   activity (2001 AR 006).
   Principal-Investigator: Grace N. Thoithi
   Funding agent: Africa Career Awards (ACA), Rockefeller Foundation, U.S.A.
   Period: 2001-2003

4. Project Title:
   Principal Investigator: Grace N. Thoithi
   Graduate Student: Beatrice Amugune
   Funding agent: African Institute for Capacity Development (AICAD).
   Period: 2005-2006



E. RESEARCH INTERESTS

1.   Market surveillance of drugs in the Kenyan market and development of methods for analysis of
     fixed dose combination drugs.

2.   Research on the chemical stability of some sugar-modified nucleosides using liquid
     chromatography

3.   Phytochemistry and pharmacological activity of Kenyan medicinal plants.

4.   Investigation of Kenyan plants containing essential oils. Determination of the chemical
     composition of oils of various plants and their antimicrobial activity.


F. THESIS AND DISSERTATIONS

1.   G. N. Karanja. Preliminary phytochemical investigations on the twigs of Croton
     macrostachyus-Euphorbiaceae family. Bachelor of Pharmacy dissertation. June 1986.

2.   G. N.Thoithi. Kinetics of hydrolysis of monoamino analogues of 2'- or 3'- deoxyadenosine and
     2'- or 3'-deoxy- 9-(ß-D-lyxo-pentofuranosyl)adenine. Master of Pharmaceutical Sciences thesis.
     Katholieke Universiteit Leuven. July 1992.




                                                                                                      2
3.    G. N. Thoithi. Investigation of the stability of some sugar-modified nucleosides using liquid
      chromatography. Doctor of Pharmaceutical Sciences thesis. Katholieke Universiteit Leuven.
      December 1996.

G. PUBLICATIONS

1.    Addae-Mensah, G. Muriuki, G. Karanja, C. Wandera, Reiner Waibel and H. Achenbach.
      Constituents of the stem bark and twigs of Croton macrostachy(u)s, Fitoterapia, LXIII
      (1992)81-82.

2.    Addae-Mensah, H. Achenbach, G. Thoithi, Reiner Waibel and J. Mwangi, Epoxychiromodine
      and other contituents of Croton megalocarpus, Phytochemistry 31(1992)20552058.

3.    G. Thoithi, A. Van Schepdael, P. Herdewijn, E. Roets and J. Hoogmartens, Liquid
      chromatographic separation of monoamino analogues of 2'- or 3'-deoxyadenosine from adenine,
      Chromatographia, 35(1993) 451-454.

4.    J. Paesen, I. Quintens, G. Thoithi, E. Roets, G. Reybrouck and J. Hoogmartens, Quantitative
      analysis of quaternary ammonium antiseptics using thin-layer densitometry. J. Chromatogr. A,
      677(1994)377-384.

5.    G. Thoithi, A. Van Schepdael, R. Busson, P. Herdewijn, E. Roets and J. Hoogmartens,
      Kinetics of hydrolysis of monoamino analogues of 2'- or 3'-deoxyadenosine and 2'- or 3'-deoxy-
      9-(ß-D-lyxo-pentofuranosyl)adenine, Nucleosides and Nucleotides, 14(1995)1559-1579.

6.    G. Thoithi, A. Van Schepdael, P. Herdewijn, E. Roets and J. Hoogmartens, Liquid
      chromatographic separation of diamino analogues of 2'- or 3'-deoxyadenosine from adenine on
      a poly(styrene-divinylbenzene) polymer column , J. Chromatogr. A, 689(1995)247-254.

7.    G. Thoithi, A. Van Schepdael, P. Herdewijn, E. Roets and J. Hoogmartens, Liquid
      chromatographic separation of hexopyranosylated cytosine nucleosides from their degradation
      products. J. Pharm. Biomed. Anal. 16(1997)533-540.

8.    J. W. Mwangi, G. N. Thoithi, I. Addae-Mensah, H. Achenbach, W. Lwande and H. Hassanali.
      Aromatic plants of Kenya III: Volatile and some non-volatile constituents of Croton sylvaticus.
      East Cent. Africa Journal Phamaceutical Sciences 1(1998)41-43.

9.    G. Thoithi, A. Van Schepdael, C. Vinckier, P. Herdewijn, E. Roets and J. Hoogmartens.
      Evaluation of the kinetics of hydrolysis of diamino analogues of 2´- or 3´-deoxyadenosine and
      of 9-(2-deoxy--D-threo-pentofuranosyl)adenine or 9-(3-deoxy--D-threo pentofuranosyl)
      adenine by liquid chromatography. Nucleosides and Nucleotide. 18 (1999)1863-1877.

10.   J. W. Mwangi, G. N. Thoithi, I. Addae-Mensah, H. Achenbach, W. Lwande and H. Hassanali.
      Aromatic plants of Kenya IV: Volatile and some non-volatile constituents of the stem bark of
      Synadenium compactum NE Br. Var. compactum, East Cent. Afr. J. Pharm. Sc. 1(1999)5-7.




                                                                                                      3
11.   J. W. Mwangi, W. Masengo, G. N. Thoithi and I. O. Kibwage. Screening of some Kenyan
      medicinal plants using the Brine Shrimp Lethality Test. East Cent. Afr. J. Pharm. Sc.
      2(1999)63-71.

12.   J. W. Mwangi, G. N. Thoithi, W. Lwande and H. Hassanali. Aromatic plants of Kenya II:
      Volatile constituents of leaf oil of Psiadia punculata (D.C.) Vatke. J. BiochemiPhysics
      8(1999)32-33.

13.   G. Thoithi, A.Van Schepdael, R. Busson, G. Janssen, E. Roets and J. Hoogmartens.
      Investigation of the kinetics of degradation of hexopyranosylated cytosine nucleosides using
      liquid chromatography. Nucleosides and Nucleotides 19(2000)189-203.

14.   J. W. Mwangi, P. K. Gathumbi, I. O. Kibwage, G. N. Thoithi and H. A. Oketch-Rabah.
      Alternative medicines and prostate enlargement-Prunus africana emphasis. Pharm. J. Kenya.
      March 2001. p 26-31.

15.   J. W. Mwangi, G. N. Thoithi, H. R. Juliani (Jr.) and J. A. Zygadlo. Composition of the
      essential oil of Microglossa pyrrhopappa var. pyrrhopappa. J. Essential Oil Research
      13(2001)229-230.

16.   F. N. Kamau, G. N. Thoithi and I. O. Kibwage. Quality of ampicillin preparations on the
      Kenyan market, East Cent. Afr. J. Pharm. Sc. 4(2001)25-29.

17.   J. W. Mwangi, G. N. Thoithi, I. O. Kibwage, J. A. Zygadlo, M. L. Lopez. M. M. Olivia, M. S.
      Demo, M. Toyota and J-C. Chalchat. Constituents of the essential oil of Cymbopogon
      afronardus Stapf. East Cent. Afr. J. Pharm. Sc. 4(2001)43-47.

18.   G. Thoithi, I. O. Kibwage, O. Kingondu, E. Roets and J. Hoogmartens. Liquid
      chromatographic separation of isoniazid, pyrazinamide and rifampicin on a reversed-phase
      silica column. East Cent. Afr. J. Pharm. Sc. 5(2002)8-14.

19.   G. N. Thoithi, K. O. Abuga, J. M. Nguyo, G. Mukindia, O. Kingondu, J. K. Ngugi and I. O.
      Kibwage, Drug quality control work in Drug Analysis and Research Unit: Observation during
      1996-2000. East Cent. Afr. J. Pharm. Sc. 5(2002)28-32.

20.   G. N. Thoithi, N. Maingi, D. Karume, P. K. Gathumbi, J. W. Mwangi and I. O. Kibwage,
      Anthelmintic and other pharmacological activities of the root bark extracts of Albizia
      anthelmintica Brongn, East Cent. Afr. J. Pharm. Sc. 5(2002)60-66.

21.   S. Malele, C. K. Mutayabarwa, J. W. Mwangi, G. N. Thoithi, A. G. Lopez, E. I. Lucini and J.
      A. Zygadlo, Microbial activity and composition of Hyptis suaveolens (L.) Poit. Essential oil
      from Tanzania. J. Essential Oil Research 15(2003)438-440.

22.   K. O. Abuga, P. M. Mwagiru, G. N. Thoithi, J. M. Nguyo, J. K. Ngugi, O. K. Kingondu, H. N.
      Mugo and I. O. Kibwage, Quality of antiretroviral drugs analyzed in the Drug Analysis
      Research Unit during 2000-2003, East Cent. Afr. J. Pharm. Sc. 6(2003)20-23.




                                                                                                     4
23.   F. K. Kamau, G. N. Thoithi, J. K. Ngugi, O. K. Kingondu and I. O. Kibwage, Quality of
      amoxycillin preparations in the Kenyan market, East Cent. Afr. J. Pharm. Sc. 6(2003)57-60.

24.   J. W. Mwangi,G. N. Thoithi, I. O. Kibwage, M. S. Demo, M. M. Oliva, M. P. Zunino and J. A.
      Zygadlo, Essential oil of Rhynchosia minima from Kenya: Composition and antibacterial
      properties. J. Essential Oil Res.17(2005)230-231.

25.   M. M. Oliva, M. S. Demo, R. S. Malele, C. K. Mutayabarwa, J. W. Mwangi, G. N. Thoithi, I.
      O. Kibwage, S. M. Faillaci, R. L. Scrivanti, A. G. Lopez and J. A. Zygadlo, Essential Oil of
      Brachylaena hutchinsii Hutch from Tanzania: Composition and Antimicrobial Activity and
      composition. East Cent. Afr. J. Pharm. Sc. 6(2003)61-63.

26.   J. W. Mwangi, N. N. Mungai, G. N. Thoithi, and I. O. Kibwage, Traditional\Herbal Medicine
      in National Healthcare in Kenya. East Cent. Afr. J. Pharm. Sc. 8(2005)22-26.

27.   I. O. Kibwage, J. W. Mwangi and G. N. Thoithi, Quality Control of Herbal Medicines. East
      Cent. Afr. J. Pharm. Sc. 8(2005)27-31.

28.   S. N. Ndwigah, G. N. Thoithi, J. W. Mwangi and I. O. Kibwage, Constituents of the stem bark
      of Dombeya rotundifolia. East Cent. Afr. J. Pharm. Sc. 8(2005)40-42.

29.   G. N. Thoithi and B. K. Amugune, Screening of some plants used traditionally for antifungal
      activity in Vihiga district, Western Kenya. AICAD Research Mini-reviews 4(2005)72-75.

30.   B. K. Amugune, I. O. Kibwage and G. N. Thoithi, Liquid chromatographic separation of
      phenobarbitone, ethosuximide, phenytoin and carbamazepine on a co-polymer column.
      Submitted toEast Cent. Afr. J. Pharm. Sc. 9(2006)




                                                                                                     5

				
DOCUMENT INFO
Shared By:
Categories:
Stats:
views:32
posted:3/10/2010
language:English
pages:5