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					     Term          Synonym     ID               is_a




symbiont role                       400 role




mutualist role                      401 symbiont role



commensal role                      402 symbiont role




parasite role                       403 symbiont role




infectious agent
                                    404 symbiont role
role




pathogen role                       405 role




host role                           408 role


role of host of
                                          symbiont role
symbiont

definitve host     primary                role of host of
                                    409
role               host role              symbiont
intermediate         secondary          role of host of
                                  410
host role            host role          symbiont


paratenic host                          role of host of
                                  411
role                                    symbiont


dead-end host        incidental         role of host of
                                  412
role                 host role          symbiont


role of host of                         role of host of
                                  413
parasite                                symbiont

role of host of
                                        role of host of
infectious                        414
                                        parasite
organism
role of host of                         role of host of
                                  415
pathogen                                symbiont
                                      host of
role of carrier of
                                  416 infectious agent
infectious agent
                                      role

infectious agent
                                  417 role
transporter role


infectious agent                        infectious agent
                                  418
vector role                             transporter role
mechanical
vector of                               infectious agent
                                  419
infectious agent                        vector role
role
biological vector
                                        infectious agent
of infectious                     420
                                        vector role
agent role

infectious agent                        infectious agent
                                  421
vehicle role                            transporter role
biological
vehicle of                              infectious agent
                                  422
infectious agent                        vehicle role
role
                           infectious agent
fomite role          423
                           vehicle role

reservoir of
infectious agent     424 role
role
role of portal of
entry of
                     430 role
infectious
organism
role of portal of
exit of infectious   431 role
organism


disinfectant role    432 role




antiseptic role      433 role



primary
                     434 role
infection role


secondary
                     435 role
infection role
                   Natural Language Definition




A role borne by an organism in symbiosis (GO:0044403).




A symbiont role borne by an organism in virtue of the fact that
both symbionts derive a growth, survival, or fitness advantage.

A symbiont role borne by an organism by virtue of the fact that it
derives a growth, survival, or fitness advantage from symbiosis,
but the other symbiont is neither advantaged nor disadvantaged.




A symbiont role borne by an organism in virtue of the fact that it
derives a growth, survival, or fitness advantage from symbiosis
while the other symbiont's growth, survival, or fitness is reduced.




A role borne by an infectious agent when part of a colony
established in an extended organism.




A role borne by an object in virtue of the fact that it is sufficiently
close to an organism towards which it has the pathogenic
disposition to allow processes resulting in disorder to occur.




A role borne by an organism by virtue of the fact it provides an
environment supportive for the survival or reproduction of an
entity of another type.
A symbiont role borne by an organism in virtue of the fact that it
provides an environment supportive for the survival and
reproduction of its partner in symbiosis.
A role of host of symbiont borne by an organism in virtue of the
fact that its partner in symbiosis reaches developmental maturity
and/or reproduces sexually in the host.
A role of host of symbiont borne by an organism in virtue of the
fact that its partner in symbiosis utilizes the host to undergo a
developmental stage transition, and the host is required for
continuation of the partner's life cycle.
A role of host of symbiont borne by an organism in virtue of the
fact that its partner in symbiosis utilizes the host to undergo a
developmental stage transition, but the host is not required for
continuation of the partner's life cycle.
A role of host of symbiont borne by an organism in virtue of the
fact that its partner in symbiosis has the infectious disposition but
cannot be transmitted (TRANS:0000000) from the host to the
partner's definitive host.
A role of host of symbiont borne by an organism in virtue of the
fact that its partner in symbiosis derives from the host a growth,
survival, or fitness advantage while the host's growth, survival, or
fitness is reduced.
A role of host of parasite borne by an organism in virtue of the fact
that its partner in symbiosis has the infectious disposition.

A role of host of symbiont borne by an organism in virtue of the
fact that its partner in symbiosis has the pathogenic disposition.




A role borne by an object in virtue of the fact an infectious agent is
located in or on the object and it has the capability to transfer
(either actively or passively) the infectious agent from one location
to another.
An infectious agent transporter role that is borne by an organism
active in the transfer of an infectious agent to an organism of
another type and in which the agent is infectious
An infectious agent vector role borne by an organism by virtue of
the fact that the infectious agent does not multiply in or on the
vector.


An infectious agent vector role borne by an organism by virtue of
the fact that the infectious agent multiplies in or on the vector.

An infectious agent transporter role borne by an object by virtue of
the fact that the object is either not alive or is not a complete
organism.
An infectious agent vehicle role borne by an object by virtue of the
fact that the object is living or contains living cells other than those
that have the infectious disposition. Examples include blood,
serum, tissue, or fresh produce.
An infectious agent vehicle role borne by an object by virtue of the
fact that the entity is not alive.

A role borne by a material entity by virtue of the fact that it is a
habitat in which an infectious agent is persisting and multiplying
and from which the infectious agent can be transmitted.


A role borne by an anatomical entity (CARO:0000000) that serves
as the site through which an infectious agent enters a host.


A role borne by an anatomical entity (CARO:0000000) that serves
as the site through which infectious agent exits a host.

A role borne by a material entity that has the antimicrobial
disposition by virtue of the fact it is in contact with a non-living
object. The role is realized in the killing and/or growth inhibition of
microorganisms on the non-living object.
A role borne by a material entity that has the antimicrobial
disposition by virtue of the fact that it is in contact with an
anatomical entity of a living organism. The role is realized in the
killing and/or growth inhibition of microorganisms on the
anatomical entity.
A role borne by an infection by virtue of the fact that, at the time
the process of establishing the infection begins, there is no other
infection in the organism.
A role borne by an infection by virtue of the fact that 1) the
infection is composed of infectious organisms of type X, and 2) at
the time the process of establishing the infection begins, the host
already has an infection composed of organisms that are not of
type X.
      Term              Synonym      ID               is_a
pathogenic
                     pathogenicity        450 disposition
disposition




infectious                                      pathogenic
                                          452
disposition                                     disposition




                                                infectious
communicability                           623
                                                disposition




disposition to
form a non-                               622 disposition
parasitic colony




                   communicable
                   disease;
infectious disease                        436 disease
                   tranmissible
                   disease

opportunistic
                                                infectious
infectious                                406
                                                disposition
disposition


primary infectious                              infectious
                                          407
disposition                                     disposition



adhesion
                                          437 disposition
disposition
virulence factor
                                  425 disposition
disposition




                                        virulence factor
toxin disposition                 426
                                        disposition

exotoxin                              toxin of
                                  427
disposition                           disposition
enterotoxin                           exotoxin
                                  428
disposition                           disposition
endotoxin                               toxin of
                                  429
disposition                             disposition
cytotoxin                         584 pending


invasion
                                  438 disposition
disposition


antimicrobial       antibiotic
                                  439 disposition
disposition         disposition
antiviral                             antimicrobial
                                  440
disposition                           disposition
antifungal                            antimicrobial
                                  441
disposition                           disposition
antibacterial                         antimicrobial
                                  442
disposition                           disposition
antiparasitic
                                  443 disposition
disposition



immunocompeten
                                  618 disposition
ce



immunosuppressi
                                  619 disposition
ve disposition
protective
                                         444 disposition
resistance


                                               protective
resistance to drug drug resistance       445
                                               resistance

host resistance to                             protective
                                         446
infectious agent                               resistance


host genetic                                 host resistance
resistance to                            587 to infectious
infectious agent                             agent


                      protective             host resistance
immunity to
                      immunity to        448 to infectious
infectious agent
                      infectious agent       agent

passive immunity                               immunity to
                                         620
to infectious agent                            infectious agent

acquired              immune memory;
                                               immunity to
immunity to           adaptive
                                               infectious agent
infectious agent      immunity
                                         621
sterilizing
                                               immunity to
immunity to                              449
                                               infectious agent
infectious agent


collective
                                         455 disposition
disposition


collective
                                               collective
resistance                               588
                                               disposition
disposition

herd immunity to                             collective
infectious                               447 resistance
organism                                     disposition
invasive
                   451 disposition
disposition


zoonotic                 infectious
                   453
disposition              disposition

reverse zoonotic         infectious
                   454
disposition              disposition


communicable
                   591 deprecate
disposition
        Natural Language Definition
A disposition to initiate processes that result in
a disorder.




A pathogenic disposition that is the disposition
to be transmitted from one organism to another
and to establish a clinically abnormal colony in
the second organism.




An infectious disposition to be transmitted
directly from one organism to another of the
same time by horizontal transmission.




A disposition to colonize an organism and
participate in mutualism or commensalism with
that organism.




A disease whose physical basis is an infection.



An infectious disposition to establish a clinically
abnormal colony only in organisms whose
defenses are compromised.

An infectious disposition to establish a clinically
abnormal colony in organisms that have intact
defenses.


A disposition borne by a biological
macromolecule that is the disposition to
participate in a process of adherence to host.
A disposition of a protein or macromolecular
complex produced by a pathogen that is the
disposition to participate in processes that
improve survival of the pathogen in a host,
improve transmission of the pathogen to a
host, or cause pathological processes in a host.
A virulence factor disposition to cause I)
malfunction of cells, ii) damage to extracellular
matrix, or iii) damage of cells to a degree that
can result in cell death.
A toxin to damage cells or extracellular matrix
by a direct enzymatic process.
An exotoxin disposition to damage cells of the
host intestinal mucosa.
A toxin disposition that inheres in a protein or
protein complex that is released from a
pathogeni only upon cytolysis.

A disposition borne by a biological
macromolecule that is the disposition to
participate in processes that facilitate the
breach of host epithelial barriers or entry into
and survival in host cells.
A disposition to kill or inhibit the growth of
microorganisms.
An antimicrobial disposition to kill or inhibit the
growth of viruses.
An antimicrobial disposition to kill or inhibit the
growth of fungal organisms.
An antimicrobial disposition to kill or inhibit the
growth of bacteria.
A disposition to kill or inhibit the growth of
eukaryotic parasites.



A disposition that is the ability to mount a
normal immune response.



A disposition whose realization negatively
regulates an immune response.
A disposition that inheres in a material entity
by virtue of the fact that the entity has a part
(e.g. a gene product), which itself has a
disposition to mitigate the damaging effects of
entities of a certain type.
A protective resistance that mitigates the
damaging effects of a drug.
A protective resistance that inheres in an
organism and mitigates the damaging effects
on that organism of an infectious agent.


A host resistance to infectious agent that
inheres in an organism in virtue of its genetic
or epigenetic qualities.


A host resistance to infectious agent that
inheres in an organism in virtue of immune
system components in the extended organism.
An immunity to infectious agent that inheres in
an organism in virtue of antibodies not
produced by that organism.
An immunity to infectious agent that inheres in
an organism in virtue of lymphocytes and
lymphocyte receptors that came into being as a
result of a primary immune response.
An immunity to infectious agent that results in
elimination of the infectious agent from the
host.
A disposition that inheres in an object
aggregate in virtue of the individual
dispositions of the constituents of that
aggregate and that does not itself inhere in any
sub- or superaggregate.
A collective disposition the realization of which
mitigates the damaging effects of some entity
on members of the aggregate.
A collective resistance disposition that inheres
in an organism population in virtue of the fact
that a sufficient number of members of the
population have immunity to an infectious
agent.
A disposition borne by an infectious organism
that is the disposition to initiate processes that
result in penetration of the epithelial barriers of
an organism of another type.
An infectious disposition that is the   disposition
to be transmitted from an infected,     non-human
host to a human host.
An infectious disposition that is the   disposition
to be transmitted from an infected,     human host
to a non-human host.

An infectious disposition to be transmitted
directly from one human host to another.
       Term                 Synonym        ID     is_a                    Natural Language Definition
                                                                 A quality that inheres in an organism in virtue of
colonized quality                           459 quality
                                                                 a colony in or on the extended organism.
                                                                 A colonized quality that inheres in an organism
                                                  colonized
infected quality                            460                  in virtue of an infection in or on the extended
                                                  quality
                                                                 organism.
                                                                 A quality that inheres in an organism in virtue of
co-infected quality                         461 infected quality the fact that the organism has two infections
                                                                 composed of different types of agents.



immunodeficient         immunocompromise                         A quality that inheres in an organism in virtue of
                                            589 quality
quality                 d quality                                the fact that it has an immunodeficiency.



                                                                 A quality that inheres in an organism in virtue of
immunocompetent                                                  the fact that the organism has all canonical
                                            457 quality
quality                                                          immune system components and none are
                                                                 disordered.



                                                                 A quality that inheres in an infection in virtue of
extracellular                                                    the fact that the infectious agents that are part
                                            472 quality
quality of infection                                             of the infection persist in the extracellular space
                                                                 of the host.

                                                                 A quality that inheres in an infection in virtue of
intracellular quality
                                            473 quality          the fact that the infectious agents that are part
of infection
                                                                 of the infection persist inside host cells.
                                                                 A quality that inheres in an infection in virtue of
systemic quality of                                              the fact that the infectious agents that are part
                                            474 quality
infection                                                        of the infection are distributed throughout the
                                                                 host.
                                                                    A quality that inheres in an infection in virtue of
local quality of                                                    the fact that the infectious agents that are part
                                             475 quality
infection                                                           of the infection are limited to a relatively small
                                                                    area of the host's body.

                                                                    A local quality of infection that inheres in an
focal quality of                                 local quality of   infection in virtue of the fact that the infection is
                                             476
infection                                        infection          local but symptoms are observed in distant
                                                                    parts of the host's body.



                                                                    A quality that inheres in an infection in virtue of
chronic quality of   persistent quality of
                                             478 quality            the fact that the infection persists for an
infection            infection
                                                                    extended period of time.




symptomatic
                                             462 pending
quality




                                                                    A quality that inheres in an infection and is the
contagiousness                               458 quality            likelihood that infectious agents part of the
                                                                    infection will spread to other hosts.


                                                                    A quality that inheres in an infectious agent and
infectious agent
                                             463 quality            is the likelihood that the infectious agent will
transmissibility
                                                                    undergo a transmission process.

                                                                    A quality that inheres in an infectious agent and
                                                                    is the liklihood that the infectious disposition will
infectivity                                  464 quality
                                                                    be realized upon exposure of a susceptible
                                                                    organism.
                                             A quality that inheres in an infectious agent and
                                             is the degree to which realizations of the
virulence             466 quality
                                             infectious disease caused by the infectious
                                             agent become severe or fatal.


                                             A quality that inheres in an entity and is the
susceptibility        467 quality            degree to which it can be harmed by another
                                             entity of a certain type.

                                             A susceptibility that inheres in an organism and
susceptibility to
                      468 susceptibility     is the degree to which it can be harmed by an
infectious agent
                                             infectious agent of a certain type.
                                             A susceptibility that is the degree to which an
drug susceptibility   469 susceptibility     entity can be harmed or inhibited from surviving
                                             by a drug.
                                             A drug susceptibility that inheres in an
drug susceptibility         drug             infectious agent and is the degree to which the
                      470
of infectious agent         susceptibility   infectious agent can be harmed or inhibited
                                             from surviving by a drug.




                                             A quality that inheres in an organism population
                                             and is the number of realizations of an
infectious disease
                      479 quality            infectious disease of a certain type for which the
incidence
                                             infectious disease course begins during a
                                             specified period of time.


                                             A quality that inheres in an organism population
                                             and is the number of organisms in the
infection incidence   480 quality            population that become infected with an
                                             infectious agent of a certain type during a
                                             specified period of time.
                                                            A quality that inheres in an organism population
                                                            and is the infectious disease incidence divided
infectious disease
                      cumulative incidence                  by the number of members of the population in
incidence                                     481 quality
                      of infectious disease                 which the infectious disease course had not
proportion
                                                            begun at the beginning of the specified period of
                                                            time.
                                                            A quality that inheres in an organism population
                                                            and is the infection incidence divided by the
infection incidence cumulative incidence
                                              482 quality   number of members of the population that are
proportion          of infection
                                                            not infected at the beginning of the specified
                                                            period of time.
                                                            A quality that inheres in an organism population
infectious disease                                          and is the infectious disease incidence
                                              483 quality
incidence rate                                              proportion divided by the period of time over
                                                            which the incidence was measured.
                                                            A quality that inheres in an organism population
infection incidence                                         and is the incidence proportion of infection
                                              484 quality
rate                                                        divided by the period of time over which the
                                                            incidence was measured.
                                                            A quality that inheres in an organism population
infectious disease                                          and is the number of realizations of an
                                              485 quality
prevalence                                                  infectious disease of a certain type in the
                                                            population at a specified time.

                                                            A quality that inheres in an organism population
infection                                                   and is the number of organisms in the
                                              486 quality
prevalence                                                  population infected with an infectious agent of a
                                                            certain type at a specified time.

                                                            A quality that inheres in an organism population
                                                            and is the number of organisms in the
infectious disease                                          population who have, at any point during their
                                              487 quality
lifetime prevalence                                         lives, been bearers of an infectious disease of a
                                                            certain type and experienced realization of the
                                                            disease.
                                          A quality that inheres in an organism population
infectious                                and is the number of organisms in the
organism             488 quality          population that have antibody specific for an
seroprevalence                            infectious agetn of a certain type in their serum
                                          at a specified time.

                                          A quality that inheres in an organism population
infectious disease                        and is the proportion of deaths in the population
                     489 quality
mortality rate                            resulting from an infectious disease of a certain
                                          type over a specified period of time.

                                          A quality that inheres in an organism population
                                          by virtue of the fact that infections of the type
infectious disease                        that causes an infectious disease of a certain
                     490 quality
endemicity                                type are maintained in the population via intra-
                                          population transmission or by transmission from
                                          a local reservoir.

                                          An infectious disease endemicity quality that
                         infectious       inheres in an organism population by virtue of
infectious disease
                     493 disease          the fact that the infectious disease endemic
hyper-endemicity
                         endemicity       level for a disease of a certain type is
                                          persistently high in the population.

                                          A quality that inheres in an organism population
                         infectious
infectious disease                        and is the infectious disease prevalence that is
                     491 disease
endemic level                             typical for that organism population and type of
                         prevalence
                                          infectious disease.

                                          A quality that inheres in an organism population
                         infectious
infectious disease                        and is the infectious disease incidence rate that
                     492 disease
endemic rate                              is typical for that organism population and type
                         incidence rate
                                          of infectious disease.

                                          A quality that inheres in an organism population
                                          by virtue of the fact that infections of the
infectious disease
                     494 quality          infectious agent that causes a certain type of
sporadicicity
                                          infectious disease occur in the population with a
                                          fluctuating prevalence.
                                      A quality that inheres in an infectious agent and
infectious agent                      is the degree to which infections lead to
                   465 merge to 450
pathogenicity                         realizations of the corresponding infectious
                                      disease.
                 Comment




Individuals with the immunodeficient quality
are often referred to as immunodeficient or
immunocompromised. Their immune systems
have a reduced ability to fight infection.
The relative size of the infected area is
determined by the canonical anatomy of the
host type.


Focal infections result from the dissemination
of toxic products of the organisms comprising
the infection.

Infections with the chronic quality are often
referred to as chronic infections. Chronic
infections may underlie chronic infectious
disease courses but may also persist in the
absence of any disease realization.




Highly contagious infections, those with a
relatively high likelihood of spread, are
referred to as contagious and are those for
which spread is likely as a result of day-to-day
activities of the host.
The transmissibility quality varies with both
the type of organism being transmitted and
the type of organism to which transmission is
happening.

This quality is measured by the proportion of
exposed who become infected.
This quality is measured by the proportion of
clincally apparent cases that are severe or
fatal.


Low susceptibility is often referred to as
resistance. In this sense, resistance is a
quality.




Incidence is used as a measure of risk. Actual
measures of incidence are based only on
reported cases and usually specify a time
interval and geographic location. Other
constraints may include population
demographics. These constraints will vary
with the context of the incidence measure.



Incidence is used as a measure of risk.
Prevalence is sometimes defined as a
proportion with total population size in the
denominator.
Mortality rate is typically expressed in units of
deaths per 1000 individuals per year.



Infectious diseases that are typical or common
to a particular population are referred to as
endemic.



Hyper-endemic infectious diseases may have
high endemci levels only in certain seasons.
A hyper-endemic disease affects all age
groups equally.


Endemic level of infectious disease is
relational to previous prevalences of the
disease.




Sporadic quality of infectious disease is
relational to previous prevalence of the
disease.
This quality is measured by the proportion of
infected individuals who develop clinically
apparent disease.
        Term             Synonym   ID               is_a                        Natural Language Definition
biological material                                                A material entity composed primarily of amino acids,
                                    613 material entity
entity                                                             nucleic acids, carbohydrates, or lipids.
replicating biological                    biological material
                                    614                            A biological material entity that is capable of replication.
material entity                           entity

                                          replicating biological   A replicating biological material entity persisting in a
colony                              615
                                          material entity          site it has colonized.
pathogen                            528 object                     An object with the pathogenic disposition.

infectious agent                    596 pathogen                   A pathogen with the infectious disposition.


infectious organism                 527 infectious agent           An infectious agent that is an organism.
infectious agent                                                   A colony that is an infectious agent or a population of
                                    616 colony
colony                                                             infectious agents.

                                                                   A disorder that has as part a clinically abnormal
infection                           586 disorder                   infectious agent colony which causes the elevated risk
                                                                   associated with the disorder.


                                                                   An infection for which the infectious agent colony is
viremia                             505 infection
                                                                   composed of virus particles located in the blood.
                                                                   An infection for which the infectious agent colony is
bacteremia                          506 infection
                                                                   composed of bacteria located in the blood.
septicemia                          507 bacteremia                 A bacteremia in which the baceteria are replicating.
                                                                   A virus that is in its assembled state consisting of
virion                              508 object                     genomic material (DNA or RNA) surrounded by coating
                                                                   molecules.

organism population                 509 material entity            An aggregate of organisms.


infectious organism                                                An organism population whose members each have an
                                    513 organism population
population                                                         infectious disposition.
                      host
                      population;
                      host of                                 An organism population whose members have an
infected population                 511 organism population
                      infectious                              infection of a certain type.
                      agent
                      population

                                                              An infected population in whose members the infectious
diseased population                 512 infected population
                                                              disease caused by the infectious agent is being realized.


                      resistant
                      population;                             An organism population whose members have acquired
immune population                   592 organism population
                      recovered                               immunity to an infectious agent of certain type.
                      population

                                                              An organism population whose members are not
susceptible           at-risk
                                    514 organism population   infected with an infectious agent of a certain type and
population            population
                                                              who lack immunity to the infectious agent.
                                                              A disorder of an immune system component that
immunodeficiency                    617 disorder              prevents the realization of a critical function of an
                                                              immune system component.
                      normal
normal resident                                               An organism population whose members are
                      resident
microbiota                          515 organism population   particpating in non-parasitic symbiosis with a particular
                      microflora
population                                                    host.
                      population

configured
infectious organism                 516 deprecate
population

infectious disorder                 504 deprecate

biological object                                             A biological object or group of biological objects in close
                                    605 deprecate
colony                                                        spatial proximity.
                Comment




The term infectious agent refers to
infectious organisms and prion proteins.




By this definition, parts of the host can
be considered part of the infection.




The aggregate of organisms may be
delineated by spatio-temporal proximity
or by demographic criteria such as age.
Biological object is taken as a primitive
and refers to an organic object capable of
creating copies of itself.
        Term            Synonym    ID                 is_a                     Natural Language Definition
                                                                   A process in which an entity comes into being as a
production                              607 process
                                                                   result of the process.
                                                                   A production process in which the resulting entity is
replication                             608 production
                                                                   of the same type as another participant.
                                                                   A process by which a replicating biological material
colonization                            609 process
                                                                   entity establishes itself in a site.
colonization of                                                    A colonization process in which the colonized site is
                                        604 colonization
organism                                                           in an extended organism.
process of
establishing a                                colonization of      A colonization of organism process that results in a
                                        606
clinically abnormal                           organism             clinically abnormal colony.
colony
infectious disease                                                 A disease course that is the realization of an
                                        495 disease course
course                                                             infectious disease.
                                                                   An infectious disease course that begins soon after
acute infectious                              infectious disease
                                        477                        infection is established and progresses rapidly to
disease course                                course
                                                                   severe stages.
                      persistent
chronic infectious    infectious              infectious disease   An infectious disease course that unfolds over a long
                                        590
disease course        disease                 course               period of time.
                      course
long-term
nonprogressing                                chronic infectious   A chronic infectious disease course that does not
                                        496
infectious disease                            disease course       progress to severe stages for a long period of time.
course
                                                                   A process in which an infectious agent comes into
host exposure to
                                        594 process                physical contact with a potential host of the
infectious agent
                                                                   infectious agent.
                                                                   A process in which a potential host of an infectious
host exposure to                                                   agent is exposed to an environment in which the
environment with                        597 process                infectious agent is present and physical contact
infectious agent                                                   between the two can occur, but such contact is not
                                                                   planned.
host living with                            host exposure to
infected household                      598 environment with
contact                                     infectious agent
                                           host exposure to
host living in
                                       599 environment with
endemic area
                                           infectious agent
release of infectious                      host exposure to
human pathogen in                      600 environment with     accidental exposure
laboratory                                 infectious agent

host coming into                           host exposure to
contact with vector of                 601 environment with
infectious organism                        infectious agent

host exposure to                           host exposure to
substance that might                   602 environment with
have infectious agent                      infectious agent

immunization against                                            A process by which an organism acquires immunity
                                       497 process
infectious agent                                                to an infectious agent.

active immunization                        immunization         An immunization process that begins with exposure
against infectious       inoculation   498 against infectious   of an organism to antigen and results in immunity
agent                                      agent                against an infectious agent.
                                           active
                                                                An active immunization process that begins with
vaccination against                        immunization
                                       499                      exposure of an organism to a vaccine and results in
infectious agent                           against infectious
                                                                immunity against an infectious agent.
                                           agent
                                           active
                                                                An active immunization process that begins with
                                           immunization
variolation                            500                      exposure to smallpox in the form of a scab from a
                                           against infectious
                                                                pustule and results in immunity against smallpox.
                                           agent
                                                                An immunization process that begins with transfer to
passive immunization                       immunization
                                                                an organism of molecules not produced by that
against infectious                     501 against infectious
                                                                organism and that confer immunity against an
agent                                      agent
                                                                infectious agent.
                                             A process in which there is a relatively significant
                                             increase in the infectious disease incidence of a
infectious disease                           certain type of infectious disease, relative to the
                     502 process
epidemic                                     endemic level of realizations of that infectious
                                             disease, in an organism population located in a
                                             geographicaly connected region.

                                             A process in which multiple infectious disease
                                             epidemics of the same type of infectious disease
infectious disease
                     503 process             unfold over overlapping periods of time and affect
pandemic
                                             organism populations located in different geographic
                                             regions, including different countries and continents.
                                             A process that negatively regulates an immune
immunosuppression    610 process
                                             response.

                                          An immunosuppression process for which all
physiologic              immunosuppressio participants are immune system components and
                     611
immunosuppression        n                which unfolds as part of the natural self-regulation of
                                          an immune response.


pathologic                 immunosuppressio An immunosuppression process which arises as the
                     612
immunosuppression          n                result of a disorder.




process of                                   A process of establishing a clinically abnormal colony
establishing an      603 deprecate           that results in a biological object colony that is part
infection                                    of an infection.
           Term             Synonym   ID               is_a
transmission period                        593 temporal interval


incubation period                          519 temporal interval


period of communicability                  520 temporal interval

dormancy period                            521 temporal interval
latent period                              518 temporal interval
         Natural Language Definition
A continuous temporal interval during which a
transmission process occurs.
A continuous temporal interval beginning with
the extablishment of an infection and ending
with the onset of symptoms.
A continuous temporal interval during which
contagiousness inhering in the bearer of a host
role.
only viruses? Do we need dormancy also?
infected but not infectious, during which the infection is latent
        Term                Synonym          ID           is_a
host                                              531 organism
potential host of
                                                  595 organism
infectious agent
immunosuppressed
                                                  456 organism
organism
symbiont                                          522 organism

obligatory symbiont                               523 organism

mutualist                                         524 organism
commensal                                         525 organism
parasite                                          526 organism
opportunistic
                                                  529 organism
pathogen
primary pathogen                                  530   organism
definitive host         primary host              532   organism
intermediate host       secondary host            533   organism
paratenic host                                    534   organism
dead-end host           incidental host           535   organism
host of parasite                                  536   organism
host of infectious
                                                  537 organism
agent
host of pathogen                                  538 organism
carrier of infectious
                                                  539 organism
agent
vector of infectious
                                                  540 organism
organism
mechanical vector of
                                                  541 organism
infectious organism
biological vector of
                                                  542 organism
infectious organism
vehicle of infectious
                                                  543 organism
organism
fomite                                            544 organism
reservoir of infectious                               material
                                                  545
organism                                              entity
                        dead-end reservoir
end reservoir of                                        material
                        of infectious             546
infectious organism                                     entity
                        organism
                                                        cellular
virulence factor                                  547
                                                        component
                                                      cellular
invasion factor        invasin                    548
                                                      component
                                                      cellular
toxin of pathogen                                 549
                                                      component
                                                    cellular
exotoxin                                      550
                                                    component
                                                    cellular
enterotoxin                                   551
                                                    component
                                                    cellular
endotoxin                                     552
                                                    component
portal of entry of                                  material
                                              553
infectious agent                                    entity
portal of exit of                                   material
                                              554
infectious agent                                    entity
                                                    material
disinfectant                                  555
                                                    entity
                                                    material
antiseptic                                    556
                                                    entity
                      adhesin; adhesion             cellular
adhesion factor                               557
                      molecule                      component
                                                    material
antimicrobial                                 558
                                                    entity
                                                    material
antiviral                                     559
                                                    entity
                                                    material
antifungal                                    560
                                                    entity
                                                    material
antiparasitic                                 561
                                                    entity
                                                    material
antibiotic                                    562
                                                    entity
                                                    material
microbicide           microbicidal [entity]   563
                                                    entity
                                                    material
viricide                                      564
                                                    entity
                                                    material
microbistatic                                 565
                                                    entity
primary infection                             566 infection
secondary infection                           567 infection
                                                    infectious
zoonosis                                      568
                                                    disease



aymptomatic                                   569 quality



subclinical                                   570 quality
resistance quality             571 quality


chronic carrier of                   material
                               572
infectious agent                     entity




symptomatic host of
                               573 role
infectious agent




viral latency            575          disposition




                                   immunity to
innate immunity to
                               576 infectious
infectious agent
                                   organism
                                   immunity to
adaptive immunity to
                               577 infectious
infectious agent
                                   organism
                                   immunity to
humoral immunity to
                               578 infectious
infectious agent
                                   organism
cell-mediated                      immunity to
immunity to infectious         579 infectious
agent                              organism
                                   immunity to
passive immunity               580 infectious
                                   organism
antibiotic resistance          581 disposition
long-term non-                     material
                               582
progressor                         entity
emerging pathogen              583 organism
            Natural Language Definition
An organism bearing the host role.
An organism that has the capability to bear the host
of infectious agent role for an infectious agent of a
certain type.
An organism that is experiencing pathologic
immunosuppression.
An organism bearing the symbiont role.
An organism bearing the symbiont role and that can
only reach developmental maturity, replicate, or
persist by playing the symbiont role.
An organism bearing the mutualist role.
An organism bearing the commensal role.
An organism bearing the parasite role.
An organism bearing the opportunistic pathogen
role.
An organism bearing the primary pathogen role.
An organism bearing the definitive host role.
An organism bearing the intermediate host role.
An organism bearing the paratenic host role.
An organism bearing the dead-end host role.
An organism bearing the host of parasite role.
An organism bearing the host of infectious agent
role.
An organism bearing the host of pathogen role.
An organism bearing the carrier of infectious agent
role.
An organism bearing the vector of infectious
organism role.
An organism bearing the mechanical vector of
infectious organism role.
An organism bearing the biological vector of
infectious organism role.
An organism bearing the vehicle of infectious
organism role.
An bject bearing the fomite role.
A material entity bearing the reservoir of infectious
organism role.
A material entity bearing the end reservoir of
infectious organism role.
A protein or macromolecular complex produced by a
pathogen and that has the virulence factor
disposition.
A protein or macromolecular complex that has the
invasion disposition (IDO:0000438).
A protein or macromolecular complex bearing the
toxin of pathogen role.
A protein or macromolecular complex bearing the
exotoxin role.
A protein or macromolecular complex bearing the
enterotoxin role.
A protein or macromolecular complex bearing the
endotoxin role, in particular LPS.
An anatomical entity bearing the portal of entry of
infectious agent role.
An anatomical entity bearing the portal of exit of
infectious agent role.
A material entity bearing the disinfectant role.

A material entity bearing the antiseptic role.
A protein or macromolecular complex that has the
adhesion disposition (IDO:0000437).
A material entity bearing the antimicrobial
disposition.
A material entity bearing the antiviral disposition.

A material entity bearing the antifungal disposition.
A material entity bearing the antiparasitic
disposition.
A material entity bearing the antibiotic disposition.
A material entity bearing an antimicrobial disposition
that is realized in a process of killing
microorganisms.
A material entity bearing an antiviral disposition that
is realized in a process of killing viruses.
A material entity bearing an antimicrobial disposition
that is realized in a process of inhibiting the growth
of microorganisms.
An infection bearing the primary infection role.
An infection bearing the secondar infection role.
An infectious disease that has as its physical basis
an infection composed of microorganims that have
the zoonotic disposition.
A quality inhering in a bearer of the host role by
virtue of the fact that the host is infected but has no
signs or symptoms; has infection but lacks
symptoms, or disease is realzied by lakcs symptoms
A quality that inheres in an infection by virtue of the
fact that the host is asymptomatic.
A quality that inheres in a bearer by virtue of the
fact that the bearer has low susceptibility to some
entity.


carrier of infectious agent that has_quality chronic



A host of infectious agent role played by a material
entity by virtue of the fact that it has symptoms of
the infectious disease associated with the infectious
agent
A latent infection is a phase in certain viruses' life
cycles in which after initial infection, virus production
ceases; some proteins are being made that actively
suppress other genes of virus. So therefore not
dormant. Virus latency is not to be confused with
clinical latency during the incubation period when a
virus is not dormant

An immunity to infectious organism realized in an
innate immune response (GO:0045087).

An immunity to infectious organism realized in an
adaptive immune response (GO:0002250).

An immunity to infectious organism realized in a
humoral immune response (GO:0006959).

An immunity to infectious organism realized in an
immune response (GO:0006955) whose participants
are T cells or other cells of the immune system.

An immunity to infectious organism that results from
a passive immunization (IDO:0000066).

				
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